Aging and the human gut microbiota—from correlation to causality

Structure, function and diversity of the healthy human microbiome

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Enterotypes of the human gut microbiome

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Changes of Intestinal Functions in Liver Cirrhosis

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Linking long-term dietary patterns with gut microbial enterotypes

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Gut microbiota in health and disease

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Gut microbiota composition correlates with diet and health in the elderly

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The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age

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Composition, variability, and temporal stability of the intestinal microbiota of the elderly

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Through Ageing, and Beyond: Gut Microbiota and Inflammatory Status in Seniors and Centenarians

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The Application of Ecological Theory Toward an Understanding of the Human Microbiome

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Intestinal Microbiota Is Influenced by Gender and Body Mass Index

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Human genetic variation and the gut microbiome in disease

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Gut microbiota: A player in aging and a target for anti-aging intervention

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The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists

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Inflamm-ageing: the role of inflammation in age-dependent cardiovascular disease

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Trimethylamine‐N‐oxide promotes brain aging and cognitive impairment in mice

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Dysfunction of the neurovascular unit in ischemic stroke and neurodegenerative diseases: An aging effect

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Lactobacillus and Bifidobacterium Improves Physiological Function and Cognitive Ability in Aged Mice by the Regulation of Gut Microbiota

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Gut microbiota changes in the extreme decades of human life: a focus on centenarians

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Characteristics of gut microbiota in people with obesity

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Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals

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Biological aging and the human gut microbiota

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On the Importance of the Microbiome and Pathobiome in Coral Health and Disease

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Differences in the gut Firmicutes to Bacteroidetes ratio across age groups in healthy Ukrainian population

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Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia

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Sex Differences in the Gut Microbiota as Potential Determinants of Gender Predisposition to Disease

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Consumption of Two Healthy Dietary Patterns Restored Microbiota Dysbiosis in Obese Patients With Metabolic Dysfunction

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Probiotics and gastrointestinal conditions: An overview of evidence from the Cochrane Collaboration

Parker, E. A. D., Roy, T., D’Adamo, C. R., & Wieland, L. S. (2017) · Nutrition · doi:10.1016/j.nut.2017.06.024 · Cited by 152

Gut Microbial Changes, Interactions, and Their Implications on Human Lifecycle: An Ageing Perspective

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Aging and sarcopenia associate with specific interactions between gut microbes, serum biomarkers and host physiology in rats

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The potential of insects as food sources – a review

de Carvalho, N. M., Madureira, A. R., & Pintado, M. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1703170 · Cited by 126

Gut microbiota and old age: Modulating factors and interventions for healthy longevity

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Aging effects on intestinal homeostasis associated with expansion and dysfunction of intestinal epithelial stem cells

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The role of the gut microbiota on animal model reproducibility

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Fermented Foods and Beverages in Human Diet and Their Influence on Gut Microbiota and Health

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Identification of Cartilage Microbial DNA Signatures and Associations With Knee and Hip Osteoarthritis

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Unlocking the Potential of the Human Microbiome for Identifying Disease Diagnostic Biomarkers

Hajjo, R., Sabbah, D. A., & Bawab, A. Q. A. (2022) · Diagnostics · doi:10.3390/diagnostics12071742 · Cited by 105

Gut microbiota and allogeneic transplantation

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Microbiome Changes during Tuberculosis and Antituberculous Therapy

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Changes in the gut microbial communities following addition of walnuts to the diet

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A great-ape view of the gut microbiome

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MVP: a microbe–phage interaction database

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How Microbiomes Affect Skin Aging: The Updated Evidence and Current Perspectives

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Gut Microbiota Disorder, Gut Epithelial and Blood–Brain Barrier Dysfunctions in Etiopathogenesis of Dementia: Molecular Mechanisms and Signaling Pathways

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Primate microbiomes over time: Longitudinal answers to standing questions in microbiome research

Björk, J. R., Dasari, M. R., Grieneisen, L., & Archie, E. A. (2019) · American Journal of Primatology · doi:10.1002/ajp.22970 · Cited by 76

Gut microbiota from high-risk men who have sex with men drive immune activation in gnotobiotic mice and in vitro HIV infection

Li, S. X., Sen, S., Schneider, J. M., Xiong, K.-N., Nusbacher, N. M., Moreno-Huizar, N., Shaffer, M., Armstrong, A. J. S., Severs, E., Kuhn, K. A., et al. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007611 · Cited by 74

Host and microbiota metabolic signals in aging and longevity

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Interactions between gut microbiota and skeletal muscle

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Minimizing confounders and increasing data quality in murine models for studies of the gut microbiome

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Genetic Pathways of Aging and Their Relevance in the Dog as a Natural Model of Human Aging

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Microbiomarkers in inflammatory bowel diseases: caveats come with caviar

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Letrozole treatment of adult female mice results in a similar reproductive phenotype but distinct changes in metabolism and the gut microbiome compared to pubertal mice

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Magnesium in joint health and osteoarthritis

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Exploring the microbiome in health and disease

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Offspring Microbiomes Differ Across Breeding Sites in a Panmictic Species

Gillingham, M. A. F., Béchet, A., Cézilly, F., Wilhelm, K., Rendón‐Martos, M., Borghesi, F., Nissardi, S., Baccetti, N., Azafzaf, H., Menke, S., et al. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00035 · Cited by 53

Long-term effects of antimicrobial drugs on the composition of the human gut microbiota

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Pseudomonas spp. as models for plant-microbe interactions

Sitaraman, R. (2015) · Frontiers in Plant Science · doi:10.3389/fpls.2015.00787 · Cited by 52

Age-Related Differences in the Gut Microbiome of Rhesus Macaques

Adriansjach, J., Baum, S. T., Lefkowitz, E. J., Pol, W. J. V. D., Buford, T. W., & Colman, R. J. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa048 · Cited by 52

Age-related analysis of the gut microbiome in a purebred dog colony

Mizukami, K., Uchiyama, J., Igarashi, H., Murakami, H., Osumi, T., Shima, A., Ishiahra, G., Nasukawa, T., Une, Y., & Sakaguchi, M. (2019) · FEMS Microbiology Letters · doi:10.1093/femsle/fnz095 · Cited by 53

Microorganisms as scaffolds of host individuality: an eco-immunity account of the holobiont

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16S rRNA sequence embeddings: Meaningful numeric feature representations of nucleotide sequences that are convenient for downstream analyses

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Alterations in bacterial communities, SCFA and biomarkers in an elderly HIV-positive and HIV-negative population in western Mexico

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Serine Deficiency Exacerbates Inflammation and Oxidative Stress via Microbiota-Gut-Brain Axis in D-Galactose-Induced Aging Mice

Wang, F., Zhou, H., Deng, L., Wang, L., Chen, J., & Zhou, X. (2020) · Mediators of Inflammation · doi:10.1155/2020/5821428 · Cited by 42

Gut Microbiota: Critical Controller and Intervention Target in Brain Aging and Cognitive Impairment

Li, H., Ni, J., & Qing, H. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.671142 · Cited by 44

Age-related changes in microbial composition and function in cynomolgus macaques

Duan, J., Yin, B., Li, W., Chai, T., Liang, W., Huang, Y., Tan, X., Zheng, P., Wu, J., Li, Y., et al. (2019) · Aging · doi:10.18632/aging.102541 · Cited by 42

Ileal antimicrobial peptide expression is dysregulated in old age

Tremblay, S., Côté, N. M. L., Grenier, G., Duclos-Lasnier, G., Fortier, L., Ilangumaran, S., & Menéndez, A. (2017) · Immunity & Ageing · doi:10.1186/s12979-017-0101-8 · Cited by 41

Association between Dysbiosis in the Gut Microbiota of Primary Osteoporosis Patients and Bone Loss

Waldbaum, J., Xhumari, J., Akinsuyi, O., Arjmandi, B. H., Anton, S. D., & Roesch, L. F. W. (2023) · Aging and Disease · doi:10.14336/ad.2023.0425 · Cited by 44

Physiological regulation of the heat shock response by glutamine: implications for chronic low-grade inflammatory diseases in age-related conditions

Leite, J. S. M., Cruzat, V. F., Krause, M. D. S., & de Bittencourt, P. I. H. (2016) · Nutrire · doi:10.1186/s41110-016-0021-y · Cited by 41

Is there a link between aging and microbiome diversity in exceptional mammalian longevity?

Hughes, G. M., Leech, J., Puechmaille, S. J., Lopez, J. V., & Teeling, E. C. (2018) · PeerJ · doi:10.7717/peerj.4174 · Cited by 43

Risk factors for esophageal cancer: emphasis on infectious agents

El-Zimaity, H. M. T., Pilato, V. D., Ringressi, M. N., Brčić, I., Rajendra, S., Langer, R., Dislich, B., Tripathi, M., Guindi, M. M., & Riddell, R. H. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13858 · Cited by 40

The differential diagnosis of Helicobacter pylori negative gastritis

El-Zimaity, H. M. T., Choi, W., Lauwers, G. Y., & Riddell, R. H. (2018) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-018-2454-6 · Cited by 42

Influence of Altered Gut Microbiota Composition on Aging and Aging-Related Diseases

Choi, J., Hur, T., & Hong, Y. (2018) · Journal of Lifestyle Medicine · doi:10.15280/jlm.2018.8.1.1 · Cited by 40

Ageing with HIV

McGettrick, P., Barco, E. Á., & Mallon, P. W. G. (2018) · Healthcare · doi:10.3390/healthcare6010017 · Cited by 41

Evidence for the Contribution of Gut Microbiota to Age-Related Anabolic Resistance

Watson, M. D., Cross, B. L., & Grosicki, G. J. (2021) · Nutrients · doi:10.3390/nu13020706 · Cited by 41

HIV and aging

Desai, S. N., & LANDAY, A. L. (2017) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000433 · Cited by 38

Metagenomic Analysis of the Gut Microbiome Reveals Enrichment of Menaquinones (Vitamin K2) Pathway in Diabetes Mellitus

Dash, N. R., & Al Bataineh, M. T. (2021) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2019.0202 · Cited by 37

Potential effects of rapeseed peptide Maillard reaction products on aging-related disorder attenuation and gut microbiota modulation in d -galactose induced aging mice

He, S., Zhang, Z., Sun, H., Zhu, Y., Cao, X., Ye, Y., Wang, J., & Cao, Y. (2019) · Food & Function · doi:10.1039/c9fo00791a · Cited by 36

Promotion of Healthy Aging Through the Nexus of Gut Microbiota and Dietary Phytochemicals

Beaver, L. M., Jamieson, P. E., Wong, C. P., Hosseinikia, M., Stevens, J. F., & Ho, E. (2025) · Advances in Nutrition · doi:10.1016/j.advnut.2025.100376 · Cited by 34

Origination, change, and modulation of geriatric disease-related gut microbiota during life

Rajoka, M. S. R., Zhao, H., Li, N., Lu, Y. P., Lian, Z., Shao, D., Jin, M., Li, Q., Zhao, L., & Shi, J. (2018) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-9264-2 · Cited by 32

Potential anti-aging effects of fermented wheat germ in aging mice

Zhao, Y., Liao, A., Liu, N., Huang, J., Lv, X., Yang, C., Chen, W., Hou, Y., Ma, L., & Hui, M. (2021) · Food Bioscience · doi:10.1016/j.fbio.2021.101182 · Cited by 30

Therapeutic Antiaging Strategies

Mishra, S. K., Balendra, V., Esposto, J., Obaid, A. A., Maccioni, R. B., Jha, N. K., Perry, G. L., Moustafa, M., Al-Shehri, M., Singh, M. P., et al. (2022) · Biomedicines · doi:10.3390/biomedicines10102515 · Cited by 34

Pathobiological Relationship of Excessive Dietary Intake of Choline/L-Carnitine: A TMAO Precursor-Associated Aggravation in Heart Failure in Sarcopenic Patients

Bin-Jumah, M. N., Gilani, S. J., Hosawi, S. B. I., Al-Abbasi, F. A., Zeyadi, M., Imam, S. S., Alshehri, S., Ghoneim, M. M., Nadeem, M. S., & Kazmi, I. A. (2021) · Nutrients · doi:10.3390/nu13103453 · Cited by 28

Differences in the gut microbiota between young and elderly persons in Korea

Lee, S. Y., Lee, D. Y., Kang, H. J., Kang, J. H., Cho, M. G., Jang, H. W., Kim, B., & Hur, S. J. (2021) · Nutrition Research · doi:10.1016/j.nutres.2020.12.013 · Cited by 27

Sex-specific differences in intestinal microbiota associated with cardiovascular diseases

García-Fernández, H., Larriva, A. P. A.-D., López-Moreno, J., Gutierrez-Mariscal, F. M., Romero‐Cabrera, J. L., Molina‐Abril, H., Torres-Peña, J. D., Rodríguez-Cano, D., Malagón, M. M., Ordovás, J. M., et al. (2024) · Biology of Sex Differences · doi:10.1186/s13293-024-00582-7 · Cited by 27

Biomolecular Mechanisms of Autoimmune Diseases and Their Relationship with the Resident Microbiota: Friend or Foe?

Topi, S., Bottalico, L., Charitos, I. A., Colella, M., Domenico, M. D., Palmirotta, R., & Santacroce, L. (2022) · Pathophysiology · doi:10.3390/pathophysiology29030041 · Cited by 26

Life-long microbiome rejuvenation improves intestinal barrier function and inflammaging in mice

Sommer, F., Bernardes, J. P., Best, L., Sommer, N., Hamm, J., Messner, B., López-Agudelo, V. A., Fazio, A., Μαρίνος, Γ., Kadibalban, A. S., et al. (2025) · Microbiome · doi:10.1186/s40168-025-02089-8 · Cited by 26

Efficacy of a Synbiotic Containing Lactobacillus paracasei DKGF1 and Opuntia humifusa in Elderly Patients with Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial

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