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Cited by 918Stroke Rehabilitation and RecoveryTranscranial Magnetic Stimulation StudiesBotulinum Toxin and Related Neurological Disorders

Rehabilitation of Motor Function after Stroke: A Multiple Systematic Review Focused on Techniques to Stimulate Upper Extremity Recovery

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Hatem, Samar M., Saussez, Geoffroy, della Faille, Margaux, Prist, Vincent, Zhang, Xue, Dispa, Delphine, Bleyenheuft, Yannick·2016·Frontiers in Human Neuroscience
DOI 10.3389/fnhum.2016.00442PMC PMC5020059
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Abstract

Stroke is one of the leading causes for disability worldwide. Motor function deficits due to stroke affect the patients' mobility, their limitation in daily life activities, their participation in society and their odds of returning to professional activities. All of these factors contribute to a low overall quality of life. Rehabilitation training is the most effective way to reduce motor impairments in stroke patients. This multiple systematic review focuses both on standard treatment methods and on innovating rehabilitation techniques used to promote upper extremity motor function in stroke patients. A total number of 5712 publications on stroke rehabilitation was systematically reviewed for relevance and quality with regards to upper extremity motor outcome. This procedure yielded 270 publications corresponding to the inclusion criteria of the systematic review. Recent technology-based interventions in stroke rehabilitation including non-invasive brain stimulation, robot-assisted training, and virtual reality immersion are addressed. Finally, a decisional tree based on evidence from the literature and characteristics of stroke patients is proposed. At present, the stroke rehabilitation field faces the challenge to tailor evidence-based treatment strategies to the needs of the individual stroke patient. Interventions can be combined in order to achieve the maximal motor function recovery for each patient. Though the efficacy of some interventions may be under debate, motor skill learning, and some new technological approaches give promising outcome prognosis in stroke motor rehabilitation.

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  • In a review by Hatem et al., robot-assisted devices and virtual reality were integrated as adjuvant therapies into stroke because of a lack of evidence even in mirror therapy.

    “In a review by Hatem et al. that evaluated the effects of various rehabilitation interventions on upper limb function after stroke, RDs and VR were integrated as adjuvant therapies into stroke because of a lack of evidence even in mirror therapy [6].”

    From High-Tech Home-Based Rehabilitation after Stroke: A Systematic Review and Meta-Analysis (2023) · cites this paper as [6]

    The robot-assisted therapy section (Supplementary Table 17) says there are insufficient arguments for integrating robot-assisted therapy into stroke rehabilitation. The virtual reality section (Supplementary Table 18) supports VR as an adjuvant therapy, but on the basis of sufficient evidence, not a lack of it. The mirror therapy section (Supplementary Table 9) likewise reports sufficient evidence supporting its integration. (LLM, conf=0.90)

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  • Several systematic reviews have evaluated the effect of new home-technologies on patient clinical outcomes, but positive results were not always guaranteed.

    “Although several systematic reviews have evaluated the effect of new home-technologies on patient clinical outcomes, positive results were not always guaranteed [6,7,8].”

    From High-Tech Home-Based Rehabilitation after Stroke: A Systematic Review and Meta-Analysis (2023) · cites this paper as [6]

    The Technology supported training sections (pages unavailable) review clinical outcomes of virtual reality and robot-assisted stroke rehabilitation and find that benefits are not assured: virtual reality alone was similar to standard treatment, while robot-assisted therapy was similar or inferior. The paper discusses these technologies in clinical settings, however, and the passages do not establish that the reviewed interventions were home technologies. (LLM, conf=0.86)

    Experimental — accuracy not yet measured

  • The results for RD are similar to existing review studies, but careful interpretation is necessary because of variable quality of traditional care in control groups.

    “Although these results are similar to the existing review studies [5,6], careful interpretation is necessary because of the variable quality of traditional care provided in the control groups.”

    From High-Tech Home-Based Rehabilitation after Stroke: A Systematic Review and Meta-Analysis (2023) · cites this paper as [6]

    The section on robot-assisted therapy for the paretic upper extremity (Supplementary Table 17; page unavailable) reviews prior studies and reports outcomes similar or inferior to standard rehabilitation, supporting the comparison with existing reviews. It does not say that interpretation requires caution because the quality of traditional care varied across control groups. (LLM, conf=0.79)

    Experimental — accuracy not yet measured

  • A limitation of the review by Hatem et al. was that it focused solely on upper limb function without focusing on the program delivery method or the effect on any other body part.

    “Another limitation of this review was that they focused solely on upper limb function without focusing on the program delivery method or the effect on any other body part.”

    From High-Tech Home-Based Rehabilitation after Stroke: A Systematic Review and Meta-Analysis (2023) · cites this paper as [6]

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Sorted by citations

Authors
Hatem, S. M., Saussez, G., della Faille, M., Prist, V., Zhang, X., Dispa, D., & Bleyenheuft, Y.
Affiliations
  • Vrije Universiteit Brussel (BE)
  • UCLouvain (BE)
  • KU Leuven (BE)
  • Cliniques Universitaires Saint-Luc (BE)
Corresponding author
Hatem, Samar M.
ORCID
Venue
Frontiers in Human Neuroscience
Publisher
Frontiers Media SA
Published
2016-09-13
Volume
10
Pages
442-442
ISSN
1662-5161 (ISSN-L)
DOI
10.3389/fnhum.2016.00442
PMC
PMC5020059
OpenAlex
W2517858288
Cited by
918
References
12
Citations by year
2026: 57 · 2025: 106 · 2024: 127 · 2023: 102 · 2022: 126 · 2021: 131 · 2020: 94 · 2019: 83 · 2018: 67 · 2017: 21 · 2016: 3 · 2014: 1
FWCI
7.35
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Human Neuroscience (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Digital Access to Libraries (submittedVersion, other-oa)
  • Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • VUBIR (Vrije Universiteit Brussel) (submittedVersion)
Funders
Fonds De La Recherche Scientifique - FNRS
Topics
  • Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
  • Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
  • Health Sciences › Medicine › Neurology › Botulinum Toxin and Related Neurological Disorders
Keywords
stroke rehabilitation, upper limb motor recovery, motor impairment, non-invasive brain stimulation, robot-assisted training, virtual reality, technology-based rehabilitation, motor skill learning, quality of life

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