From the Quantum Approximate Optimization Algorithm to a Quantum Alternating Operator Ansatz
Open accessAbstract
The next few years will be exciting as prototype universal quantum processors emerge, enabling the implementation of a wider variety of algorithms. Of particular interest are quantum heuristics, which require experimentation on quantum hardware for their evaluation and which have the potential to significantly expand the breadth of applications for which quantum computers have an established advantage. A leading candidate is Farhi et al.’s quantum approximate optimization algorithm, which alternates between applying a cost function based Hamiltonian and a mixing Hamiltonian. Here, we extend this framework to allow alternation between more general families of operators. The essence of this extension, the quantum alternating operator ansatz, is the consideration of general parameterized families of unitaries rather than only those corresponding to the time evolution under a fixed local Hamiltonian for a time specified by the parameter. This ansatz supports the representation of a larger, and potentially more useful, set of states than the original formulation, with potential long-term impact on a broad array of application areas. For cases that call for mixing only within a desired subspace, refocusing on unitaries rather than Hamiltonians enables more efficiently implementable mixers than was possible in the original framework. Such mixers are particularly useful for optimization problems with hard constraints that must always be satisfied, defining a feasible subspace, and soft constraints whose violation we wish to minimize. More efficient implementation enables earlier experimental exploration of an alternating operator approach, in the spirit of the quantum approximate optimization algorithm, to a wide variety of approximate optimization, exact optimization, and sampling problems. In addition to introducing the quantum alternating operator ansatz, we lay out design criteria for mixing operators, detail mappings for eight problems, and provide a compendium with brief descriptions of mappings for a diverse array of problems.
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Ansatz adaptations can occur as a byproduct, as in the Quantum Alternating Operator Ansatz where the primary goal is to find a mixing Hamiltonian that ensures staying in the feasible subspace.
“Besides the mentioned ansatz search, as the driving force behind ansatz adaptation, there is also the possibility of having these adaptations as a byproduct, like it happens, e.g., within the Quantum Alternating Operator Ansatz where the primary goal is to find a mixing Hamiltonian that ensures to stay in the feasible subspace [11, 58, 95, 112, 116, 117, 120, 127].”
From Quantum Combinatorial Optimization in the NISQ Era: A Systematic Mapping Study (2024) · cites this paper as [58]
The Introduction and Conclusions describe designing mixing operators that keep evolution within the feasible subspace, supporting that part of the claim. But the paper presents its extension of the ansatz as an explicit aim, not a byproduct, and says its mixers need not arise from a fixed mixing Hamiltonian. The indexed passages provide section labels but no page numbers. (LLM, conf=0.86)
Experimental — accuracy not yet measuredHadfield et al. propose the Quantum Alternating Operator Ansatz where the problem-agnostic mixing Hamiltonian of the original QAOA is replaced by a mixing Hamiltonian that enforces constraints and ensures transitions between all pairs of feasible states.
“Hadfield et al. [58] propose the Quantum Alternating Operator Ansatz where the problem-agnostic mixing Hamiltonian of the original QAOA is replaced by a mixing Hamiltonian that enforces constraints and ensures that transitions between all pairs of feasible states are provided.”
From Quantum Combinatorial Optimization in the NISQ Era: A Systematic Mapping Study (2024) · cites this paper as [58]
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measuredDownsides of the Quantum Alternating Operator Ansatz are the resulting deep quantum circuits and the complexity of the mixer design.
“Downsides of the proposed approach are the resulting deep quantum circuits and the complexity of the mixer design.”
From Quantum Combinatorial Optimization in the NISQ Era: A Systematic Mapping Study (2024) · cites this paper as [58]
The Conclusions (page unavailable) discuss trade-offs between mixer-design complexity, gate complexity, and QAOA circuit depth. That supports these as potential implementation challenges, but not the unqualified claim that the ansatz results in deep circuits: the paper also describes mixer constructions that reduce depth. (LLM, conf=0.84)
Experimental — accuracy not yet measuredThe parameterized quantum circuits often utilize multi-controlled operations to encode constraints into the ansatz.
“However, the parameterized quantum circuits often utilize multi-controlled operations to encode constraints into the ansatz, e.g., the Quantum Alternating Operator Ansatz [58].”
From Quantum Combinatorial Optimization in the NISQ Era: A Systematic Mapping Study (2024) · cites this paper as [58]
The Quantum Alternating Operator Ansatz algorithm overcomes the limitation of unconstrained algorithms by using a parameterized circuit that limits the quantum evolution to a constraint-preserving subspace.
“The Quantum Alternating Operator Ansatz algorithm22 overcomes this limitation by using a parameterized circuit which limits the quantum evolution to a constraint-preserving subspace.”
From Constrained quantum optimization for extractive summarization on a trapped-ion quantum computer (2022) · cites this paper as [22]
Hybrid quantum-classical algorithms provide ways to use noisy intermediate-scale quantum computers for practical applications.
“Hybrid quantum-classical algorithms, such as the variational quantum eigensolver 2,3 (VQE) and the quantum approximate optimization algorithm 4,5 (QAOA), provide ways to use NISQ computers for practical applications.”
From A generative modeling approach for benchmarking and training shallow quantum circuits (2019) · cites this paper as [5]
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Variational quantum algorithms
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“As discussed in Section II B, the UCC ansatz for VQE of the quantum alternating operator ansatz [22, 23] for optimization are problem-inspired ansatze which are usually trainable even when randomly initialized.”
BackgroundMethodNoisy intermediate-scale quantum algorithms
Bharti, K., Cervera-Lierta, A., Kyaw, T. H., Haug, T., Alperin-Lea, S., Anand, A., Degroote, M., Heimonen, H., Kottmann, J. S., Menke, T., et al. (2022) · Reviews of Modern Physics · doi:10.1103/revmodphys.94.015004 · Cited by 1,726 · see citing works
Cost function dependent barren plateaus in shallow parametrized quantum circuits
Cerezo, M., Sone, A., Volkoff, T., Cincio, L., & Coles, P. J. (2021) · Nature Communications · doi:10.1038/s41467-021-21728-w · Cited by 1,047 · see citing works
Noise-induced barren plateaus in variational quantum algorithms
Wang, S., Fontana, E., Cerezo, M., Sharma, K., Sone, A., Cincio, L., & Coles, P. J. (2021) · Nature Communications · doi:10.1038/s41467-021-27045-6 · Cited by 773 · see citing works
Connecting Ansatz Expressibility to Gradient Magnitudes and Barren Plateaus
Holmes, Z., Sharma, K., Cerezo, M., & Coles, P. J. (2022) · PRX Quantum · doi:10.1103/prxquantum.3.010313 · Cited by 570 · see citing works
Quantum approximate optimization of non-planar graph problems on a planar superconducting processor
Harrigan, M. P., Sung, K. J., Neeley, M., Satzinger, K. J., Arute, F., Arya, K., Atalaya, J., Bardin, J. C., Barends, R., Boixo, S., et al. (2021) · Nature Physics · doi:10.1038/s41567-020-01105-y · Cited by 564 · see citing works
Self-citationA generative modeling approach for benchmarking and training shallow quantum circuits
Benedetti, M., Garcia-Pintos, D., Perdomo, O., Leyton-Ortega, V., Nam, Y., & Perdomo-Ortiz, A. (2019) · npj Quantum Information · doi:10.1038/s41534-019-0157-8 · Cited by 379 · see citing works
Quantum approximate optimization algorithm for MaxCut: A fermionic view
Wang, Z., Hadfield, S., Jiang, Z., & Rieffel, E. G. (2018) · Physical Review A · doi:10.1103/physreva.97.022304 · Cited by 353 · see citing works
Self-citationQAOA for Max-Cut requires hundreds of qubits for quantum speed-up
Guerreschi, G. G., & Matsuura, A. Y. (2019) · Scientific Reports · doi:10.1038/s41598-019-43176-9 · Cited by 337 · see citing works
Layerwise learning for quantum neural networks
Skolik, A., McClean, J. R., Mohseni, M., van der Smagt, P., & Leib, M. (2021) · Quantum Machine Intelligence · doi:10.1007/s42484-020-00036-4 · Cited by 324 · see citing works
Warm-starting quantum optimization
Egger, D. J., Mareček, J., & Woerner, S. (2021) · Quantum · doi:10.22331/q-2021-06-17-479 · Cited by 269 · see citing works
Reverse quantum annealing approach to portfolio optimization problems
Venturelli, D., & Kondratyev, A. (2019) · Quantum Machine Intelligence · doi:10.1007/s42484-019-00001-w · Cited by 233 · see citing works
Self-citationThe prospects of quantum computing in computational molecular biology
Outeiral, C., Strahm, M., Shi, J., Morris, G. M., Benjamin, S. C., & Deane, C. M. (2021) · WIREs Computational Molecular Science · doi:10.1002/wcms.1481 · Cited by 232 · see citing works
Wang, Z., Rubin, N. C., Dominy, J. M., & Rieffel, E. G. (2020) · Physical Review A · doi:10.1103/physreva.101.012320 · Cited by 190 · see citing works
Self-citationDesigning metamaterials with quantum annealing and factorization machines
Kitai, K., Guo, J., Ju, S., Tanaka, S., Tsuda, K., Shiomi, J., & Tamura, R. (2020) · Physical Review Research · doi:10.1103/physrevresearch.2.013319 · Cited by 181 · see citing works
Challenges and opportunities in quantum optimization
Abbas, A., Ambainis, A., Augustino, B., Bärtschi, A., Buhrman, H., Coffrin, C., Cortiana, G., Dunjko, V., Egger, D. J., Elmegreen, B. G., et al. (2024) · Nature Reviews Physics · doi:10.1038/s42254-024-00770-9 · Cited by 201 · see citing works
“The quantum alternating operator ansatz 79,80 generalizes the QAOA to much wider classes of problems and encodings, in particular to problems with hard constraints.”
Self-citationResource-efficient quantum algorithm for protein folding
Robert, A., Barkoutsos, P. K., Woerner, S., & Tavernelli, I. (2021) · npj Quantum Information · doi:10.1038/s41534-021-00368-4 · Cited by 201 · see citing works
Avoiding local minima in variational quantum eigensolvers with the natural gradient optimizer
Wierichs, D., Gogolin, C., & Kastoryano, M. (2020) · Physical Review Research · doi:10.1103/physrevresearch.2.043246 · Cited by 172 · see citing works
Formulating and Solving Routing Problems on Quantum Computers
Harwood, S., Gambella, C., Trenev, D., Simonetto, A., Bernal Neira, D., & Greenberg, D. (2021) · IEEE Transactions on Quantum Engineering · doi:10.1109/tqe.2021.3049230 · Cited by 145 · see citing works
Large gradients via correlation in random parameterized quantum circuits
Volkoff, T., & Coles, P. J. (2021) · Quantum Science and Technology · doi:10.1088/2058-9565/abd891 · Cited by 143 · see citing works
Benchmarking the quantum approximate optimization algorithm
Willsch, M., Willsch, D., Jin, F., De Raedt, H., & Michielsen, K. (2020) · Quantum Information Processing · doi:10.1007/s11128-020-02692-8 · Cited by 128 · see citing works
Deterministic Preparation of Dicke States
Bärtschi, A., & Eidenbenz, S. (2019) · Lecture Notes in Computer Science · doi:10.1007/978-3-030-25027-0_9 · Cited by 127 · see citing works
Grover Mixers for QAOA: Shifting Complexity from Mixer Design to State Preparation
Bartschi, A., & Eidenbenz, S. (2020) · 2020 IEEE International Conference on Quantum Computing and Engineering (QCE) · doi:10.1109/qce49297.2020.00020 · Cited by 122 · see citing works
Benchmarking the performance of portfolio optimization with QAOA
Brandhofer, S., Braun, D., Dehn, V., Hellstern, G., Hüls, M., Ji, Y., Polian, I., Bhatia, A. S., & Wellens, T. (2022) · Quantum Information Processing · doi:10.1007/s11128-022-03766-5 · Cited by 106 · see citing works
Optimal layout synthesis for quantum computing
Tan, B., & Cong, J. (2020) · Proceedings of the 39th International Conference on Computer-Aided Design · doi:10.1145/3400302.3415620 · Cited by 126 · see citing works
Universal variational quantum computation
Biamonte, J. (2021) · Physical Review A · doi:10.1103/physreva.103.l030401 · Cited by 102 · see citing works
Biology and medicine in the landscape of quantum advantages
Cordier, B. A., Sawaya, N. P. D., Guerreschi, G. G., & McWeeney, S. K. (2022) · Journal of The Royal Society Interface · doi:10.1098/rsif.2022.0541 · Cited by 87 · see citing works
Quantum-optimal-control-inspired ansatz for variational quantum algorithms
Choquette, A., Di Paolo, A., Barkoutsos, P. K., Sénéchal, D., Tavernelli, I., & Blais, A. (2021) · Physical Review Research · doi:10.1103/physrevresearch.3.023092 · Cited by 86 · see citing works
Classical variational simulation of the Quantum Approximate Optimization Algorithm
Medvidović, M., & Carleo, G. (2021) · npj Quantum Information · doi:10.1038/s41534-021-00440-z · Cited by 79 · see citing works
Layer VQE: A Variational Approach for Combinatorial Optimization on Noisy Quantum Computers
Liu, X., Angone, A., Shaydulin, R., Safro, I., Alexeev, Y., & Cincio, L. (2022) · IEEE Transactions on Quantum Engineering · doi:10.1109/tqe.2021.3140190 · Cited by 78 · see citing works
Minimizing Estimation Runtime on Noisy Quantum Computers
Wang, G., Koh, D. E., Johnson, P. D., & Cao, Y. (2021) · PRX Quantum · doi:10.1103/prxquantum.2.010346 · Cited by 77 · see citing works
Optimizing quantum heuristics with meta-learning
Wilson, M., Stromswold, R., Wudarski, F., Hadfield, S., Tubman, N. M., & Rieffel, E. G. (2021) · Quantum Machine Intelligence · doi:10.1007/s42484-020-00022-w · Cited by 79 · see citing works
Self-citationTransferability of optimal QAOA parameters between random graphs
Galda, A., Liu, X., Lykov, D., Alexeev, Y., & Safro, I. (2021) · 2021 IEEE International Conference on Quantum Computing and Engineering (QCE) · doi:10.1109/qce52317.2021.00034 · Cited by 72 · see citing works
Constrained quantum optimization for extractive summarization on a trapped-ion quantum computer
Niroula, P., Shaydulin, R., Yalovetzky, R., Minssen, P., Herman, D., Hu, S., & Pistoia, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-20853-w · Cited by 59 · see citing works
Variational learning of Grover's quantum search algorithm
Morales, M. E. S., Tlyachev, T., & Biamonte, J. (2018) · Physical Review A · doi:10.1103/physreva.98.062333 · Cited by 57 · see citing works
Characterizing local noise in QAOA circuits
Marshall, J., Wudarski, F., Hadfield, S., & Hogg, T. (2020) · IOP SciNotes · doi:10.1088/2633-1357/abb0d7 · Cited by 61 · see citing works
Self-citationEfficient Encoding of the Weighted MAX $$k$$-CUT on a Quantum Computer Using QAOA
Fuchs, F. G., Kolden, H. Ø., Aase, N. H., & Sartor, G. (2021) · SN Computer Science · doi:10.1007/s42979-020-00437-z · Cited by 56 · see citing works
Recent Advances in Quantum Computing for Drug Discovery and Development
Wang, P.-H., Chen, J.-H., Yang, Y.-Y., Lee, C., & Tseng, Y. J. (2023) · IEEE Nanotechnology Magazine · doi:10.1109/mnano.2023.3249499 · Cited by 58 · see citing works
Quantum Annealing vs. QAOA: 127 Qubit Higher-Order Ising Problems on NISQ Computers
Pelofske, E., Bärtschi, A., & Eidenbenz, S. (2023) · Lecture Notes in Computer Science · doi:10.1007/978-3-031-32041-5_13 · Cited by 47 · see citing works
Quantum Algorithms for Mixed Binary Optimization Applied to Transaction Settlement
Braine, L., Egger, D. J., Glick, J., & Woerner, S. (2021) · IEEE Transactions on Quantum Engineering · doi:10.1109/tqe.2021.3063635 · Cited by 51 · see citing works
Dalyac, C., Henriet, L., Jeandel, E., Lechner, W., Perdrix, S., Porcheron, M., & Veshchezerova, M. (2021) · EPJ Quantum Technology · doi:10.1140/epjqt/s40507-021-00100-3 · Cited by 46 · see citing works
Quantum Approximation for Wireless Scheduling
Choi, J., Oh, S., & Kim, J. (2020) · Applied Sciences · doi:10.3390/app10207116 · Cited by 44 · see citing works
Parameter Setting in Quantum Approximate Optimization of Weighted Problems
Sureshbabu, S. H., Herman, D., Shaydulin, R., Basso, J., Chakrabarti, S., Sun, Y., & Pistoia, M. (2024) · Quantum · doi:10.22331/q-2024-01-18-1231 · Cited by 41 · see citing works
The Useful Quantum Computing Techniques for Artificial Intelligence Engineers
Choi, J., Oh, S., & Kim, J. (2020) · 2020 International Conference on Information Networking (ICOIN) · doi:10.1109/icoin48656.2020.9016555 · Cited by 39 · see citing works
Exploiting Symmetry Reduces the Cost of Training QAOA
Shaydulin, R., & Wild, S. M. (2021) · IEEE Transactions on Quantum Engineering · doi:10.1109/tqe.2021.3066275 · Cited by 39 · see citing works
Peptide conformational sampling using the Quantum Approximate Optimization Algorithm
Boulebnane, S., Lucas, X., Meyder, A., Adaszewski, S., & Montanaro, A. (2023) · npj Quantum Information · doi:10.1038/s41534-023-00733-5 · Cited by 32 · see citing works
Toward Quantum Gate-Model Heuristics for Real-World Planning Problems
Stollenwerk, T., Hadfield, S., & Wang, Z. (2020) · IEEE Transactions on Quantum Engineering · doi:10.1109/tqe.2020.3030609 · Cited by 29 · see citing works
Self-citationError mitigation with Clifford quantum-circuit data
Czarnik, P., Arrasmith, A., Coles, P. J., & Cincio, L. (2021) · Quantum · doi:10.22331/q-2021-11-26-592 · Cited by 27 · see citing works
Quantum Combinatorial Optimization in the NISQ Era: A Systematic Mapping Study
Gemeinhardt, F., Garmendia, A., Wimmer, M., Weder, B., & Leymann, F. (2024) · ACM Computing Surveys · doi:10.1145/3620668 · Cited by 22 · see citing works
“Hadfield et al. [58] propose the Quantum Alternating Operator Ansatz where the problem-agnostic mixing Hamiltonian of the original QAOA is replaced by a mixing Hamiltonian that enforces constraints and ensures that transitions between all pairs of feasible states are provided.”
BackgroundMethodInfluentialEnergy-Efficient Cluster Head Selection via Quantum Approximate Optimization
Choi, J., Oh, S., & Kim, J. (2020) · Electronics · doi:10.3390/electronics9101669 · Cited by 20 · see citing works
QED driven QAOA for network-flow optimization
Zhang, Y., Zhang, R., & Potter, A. C. (2021) · Quantum · doi:10.22331/q-2021-07-27-510 · Cited by 19 · see citing works
High-Round QAOA for MAX $k$-SAT on Trapped Ion NISQ Devices
Pelofske, E., Bärtschi, A., Golden, J., & Eidenbenz, S. (2023) · 2023 IEEE International Conference on Quantum Computing and Engineering (QCE) · doi:10.1109/qce57702.2023.00064 · Cited by 15 · see citing works
The Quantum Alternating Operator Ansatz for Satisfiability Problems
Golden, J., Bärtschi, A., O'Malley, D., & Eidenbenz, S. (2023) · 2023 IEEE International Conference on Quantum Computing and Engineering (QCE) · doi:10.1109/qce57702.2023.00042 · Cited by 13 · see citing works
“Combinatorial optimization is widely viewed to be a promising application domain for quantum computing, and the Quantum Approximate Optimization Algorithm [5] and its generalization the Quantum Alternate Operator Ansatz [9] – both abbreviated as QAOA – are the most prominent algorithms for this application.”
BackgroundImproving Quantum Approximate Optimization by Noise-Directed Adaptive Remapping
Maciejewski, F. B., Biamonte, J., Hadfield, S., & Venturelli, D. (2025) · Quantum · doi:10.22331/q-2025-11-06-1906 · Cited by 10 · see citing works
Self-citationChukwu, U., Dridi, R., Berwald, J., Booth, M., Dawson, J., Le, D., Wainger, M., & Reinhardt, S. P. (2020) · 2020 IEEE High Performance Extreme Computing Conference (HPEC) · doi:10.1109/hpec43674.2020.9286230 · Cited by 9 · see citing works
- Authors
- Hadfield, S., Wang, Z., O’Gorman, B., Rieffel, E. G., Venturelli, D., & Biswas, R.
- Affiliations
- Ames Research Center (US)
- Corresponding author
- Hadfield, Stuart
- Venue
- Algorithms
- Publisher
- MDPI AG
- Published
- 2019-02-12
- Volume
- 12
- Issue
- 2
- Pages
- 34
- ISSN
- 1999-4893 (ISSN-L)
- OpenAlex
- W2754868542
- Cited by
- 772
- References
- 94
- Citations by year
- 2026: 92 · 2025: 130 · 2024: 149 · 2023: 124 · 2022: 94 · 2021: 103 · 2020: 49 · 2019: 22 · 2018: 7 · 2017: 2
- FWCI
- 30.80
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Algorithms (publishedVersion, cc-by)
- arXiv (Cornell University) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- arXiv (Cornell University)
- Funders
- National Aeronautics and Space Administration (NNX12AK33A)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Quantum Computing Algorithms and Architecture
- Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Quantum many-body systems
- Physical Sciences › Computer Science › Artificial Intelligence › Metaheuristic Optimization Algorithms Research
- Keywords
- quantum approximate optimization algorithm, Quantum Alternating Operator Ansatz, mixing operators, hard and soft constraints, combinatorial optimization, quantum annealing, problem mapping
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