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Potential Health Benefit of Garlic Based on Human Intervention Studies: A Brief Overview
Open accessAbstract
Garlic is a polyphenolic and organosulfur enriched nutraceutical spice consumed since ancient times. Garlic and its secondary metabolites have shown excellent health-promoting and disease-preventing effects on many human common diseases, such as cancer, cardiovascular and metabolic disorders, blood pressure, and diabetes, through its antioxidant, anti-inflammatory, and lipid-lowering properties, as demonstrated in several in vitro, in vivo, and clinical studies. The present review aims to provide a comprehensive overview on the consumption of garlic, garlic preparation, garlic extract, and garlic extract-derived bioactive constituents on oxidative stress, inflammation, cancer, cardiovascular and metabolic disorders, skin, bone, and other common diseases. Among the 83 human interventional trials considered, the consumption of garlic has been reported to modulate multiple biomarkers of different diseases; in addition, its combination with drugs or other food matrices has been shown to be safe and to prolong their therapeutic effects. The rapid metabolism and poor bioavailability that have limited the therapeutic use of garlic in the last years are also discussed.
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“Mainly contained in onion and garlic, they have shown to exert beneficial effects against cardiovascular diseases, cancer, aging, inflammation, OS, and infection, among the others [202,203].”
From The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence (2022) · cites this paper as [202]
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“Alliin, allicin, allyl sulphides, allylcysteines and other sulphur-containing compounds have long been known for their antioxidant properties [202].”
From The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence (2022) · cites this paper as [202]
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1 retracted
Aalami-Harandi, R., Karamali, M., & Asemi, Z. (2014) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2014.977248 · Cited by 49
RetractedGlobal aetiology and epidemiology of type 2 diabetes mellitus and its complications
Zheng, Y., Ley, S. H., & Hu, F. B. (2018) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2017.151 · Cited by 5,697
Cancer treatment and survivorship statistics, 2019
Miller, K. D., Nogueira, L., Mariotto, A. B., Rowland, J. H., Yabroff, K. R., Alfano, C. M., Jemal, A., Kramer, J. L., & Siegel, R. L. (2019) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21565 · Cited by 4,366
Siti, H. N., Kamisah, Y., & Jaarin, K. (2015) · Vascular Pharmacology · doi:10.1016/j.vph.2015.03.005 · Cited by 925
Samson, S. L., & Garber, A. J. (2014) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2013.09.009 · Cited by 828
Ma, J.-L., Zhang, L., Brown, L. M., Li, W., Shen, L., Pan, K., Liu, W., Hu, Y., Han, Z.-X., Crystal-Mansour, S., et al. (2012) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djs003 · Cited by 460
You, W., Brown, L. M., Zhang, L., Li, J., Jin, M., Chang, Y.-S., Ma, J., Pan, K., Liu, W., Hu, Y., et al. (2006) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djj264 · Cited by 443
Effect of Garlic on Total Serum Cholesterol
Warshafsky, S., Kamer, R. S., & Sivak, S. L. (1993) · Annals of Internal Medicine · doi:10.7326/0003-4819-119-7_part_1-199310010-00009 · Cited by 372
Health Benefits of Culinary Herbs and Spices
Jiang, T. A. (2019) · Journal of AOAC International · doi:10.5740/jaoacint.18-0418 · Cited by 353
A meta-analysis of the effect of garlic on blood pressure
Silagy, C., & Neil, H. A. W. (1994) · Journal of Hypertension · doi:10.1097/00004872-199404000-00017 · Cited by 340
Black garlic: A critical review of its production, bioactivity, and application
Kimura, S., Tung, Y., Pan, M., Su, N., Lai, Y., & Cheng, K. (2016) · Journal of Food and Drug Analysis · doi:10.1016/j.jfda.2016.11.003 · Cited by 311
Our Time: A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke)
Smith, S. C., Collins, A., Ferrari, R., Holmes, D. R., Løgstrup, S., McGhie, D. V., Ralston, J., Sacco, R. L., Stam, H. C. G., Taubert, K. A., et al. (2012) · Circulation · doi:10.1161/cir.0b013e318267e99f · Cited by 306
Garlic Shows Promise for Improving Some Cardiovascular Risk Factors
Ackermann, R. T., Mulrow, C. D., Ramirez, G., Gardner, C. D., Morbidoni, L., & Lawrence, V. A. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.6.813 · Cited by 295
Steiner, M., Khan, A., Holbert, D., & Lin, R. (1996) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/64.6.866 · Cited by 283
Lawson, L. D., Ransom, D. K., & Hughes, B. G. (1992) · Thrombosis Research · doi:10.1016/0049-3848(92)90234-2 · Cited by 271
Freeman, F., & Kodera, Y. (1995) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00057a004 · Cited by 247
Li, W., Zhang, J., Ma, J., Li, Z., Zhang, L., Zhang, Y., Guo, Y., Zhou, T., Li, J., Shen, L., et al. (2019) · BMJ · doi:10.1136/bmj.l5016 · Cited by 242
Self-citationAged garlic extract reduces blood pressure in hypertensives: a dose–response trial
Ried, K., Frank, O. R., & Stocks, N. P. (2012) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2012.178 · Cited by 240
Magder, S. A. (2018) · Critical Care · doi:10.1186/s13054-018-2171-1 · Cited by 234
Composition, stability, and bioavailability of garlic products used in a clinical trial
Lawson, L. D., & Gardner, C. D. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf050536+ · Cited by 227
Ried, K. (2016) · Journal of Nutrition · doi:10.3945/jn.114.202192 · Cited by 225
Strawberry anthocyanin and its association with postprandial inflammation and insulin
Edirisinghe, I., Banaszewski, K., Cappozzo, J. C., Krishnankutty, S., Ellis, C. L., Tadapaneni, R. K., Kappagoda, C. T., & Burton‐Freeman, B. M. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511001176 · Cited by 218
Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods
Lawson, L. D., & Hunsaker, S. M. (2018) · Nutrients · doi:10.3390/nu10070812 · Cited by 207
Gu, C., Howell, K. S., Dunshea, F. R., & Suleria, H. A. R. (2019) · Antioxidants · doi:10.3390/antiox8090405 · Cited by 200
Intralesional Immunotherapy of Warts With Mumps, Candida, and Trichophyton Skin Test Antigens
Horn, T. D., Johnson, S. M., Helm, R. M., & Roberson, P. K. (2005) · Archives of Dermatology · doi:10.1001/archderm.141.5.589 · Cited by 193
Rana, S. V., Pal, R., Vaiphei, K., Sharma, S. K., & Ola, R. P. (2011) · Nutrition Research Reviews · doi:10.1017/s0954422410000338 · Cited by 191
Gorinstein, S., Hanna Leontowicz, A., Maria Leontowicz, A., Namieśnik, J., Najman, K., Drzewiecki, J., Cvikrová, M., Martincová, O., Katrich, E., & Trakhtenberg, S. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf800038h · Cited by 184
Extracts from the history and medical properties of garlic
Petrovska, B., & Cekovska, S. (2010) · Pharmacognosy Reviews/Bioinformatics Trends/Pharmacognosy review · doi:10.4103/0973-7847.65321 · Cited by 183
Fenwick, G. R., Hanley, A. B., & Whitaker, J. R. (1985) · C R C Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398509527417 · Cited by 167
Pharmacokinetics of the Garlic CompoundS-Allylcysteine
Nagae, S., Ushijima, M., Hatono, S., Imai, J., Kasuga, S., Matsuura, H., Itakura, Y., & Higashi, Y. (1994) · Planta Medica · doi:10.1055/s-2006-959461 · Cited by 165
Ishikawa, H., Saeki, T., Otani, T., Suzuki, T., Shimozuma, K., Nishino, H., Fukuda, S., & Morimoto, K. (2006) · Journal of Nutrition · doi:10.1093/jn/136.3.816s · Cited by 151
Aged garlic extract improves endothelial function in men with coronary artery disease
Williams, M. J. A., Sutherland, W. H. F., McCormick, M. P., Yeoman, D. J., & de Jong, S. A. (2005) · Phytotherapy Research · doi:10.1002/ptr.1663 · Cited by 142
Smyth, A. R., Cifelli, P., Ortori, C. A., Righetti, K., Lewis, S., Erskine, P., Holland, E. D., Givskov, M., Williams, P. M., Cámara, M., et al. (2010) · Pediatric Pulmonology · doi:10.1002/ppul.21193 · Cited by 141
On the effect of garlic on plasma lipids and lipoproteins in mild hypercholesterolaemia
Simons, L. A., Balasubramaniam, S., von Konigsmark, M., Parfitt, A., Simons, J., & Peters, W. L. (1995) · Atherosclerosis · doi:10.1016/0021-9150(94)05449-s · Cited by 141
Padiya, R., Chowdhury, D., Borkar, R. M., Srinivas, R., Bhadra, M. P., & Banerjee, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094228 · Cited by 140
Our Time: A Call to Save Preventable Death From Cardiovascular Disease (Heart Disease and Stroke)
Smith, S. C., Collins, A., Ferrari, R., Holmes, D. R., Løgstrup, S., McGhie, D. V., Ralston, J., Sacco, R. L., Stam, H. C. G., Taubert, K. A., et al. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.08.962 · Cited by 140
Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients
Kojuri, J., Vosoughi, A. R., & Akrami, M. (2007) · Lipids in Health and Disease · doi:10.1186/1476-511x-6-5 · Cited by 133
Ashraf, R., Khan, R. A., & Ashraf, I. (2011) · PubMed · Cited by 132
Aged Garlic Extract Modifies Human Immunity
Percival, S. S. (2016) · Journal of Nutrition · doi:10.3945/jn.115.210427 · Cited by 132
Aged Garlic Extract May Be Safe for Patients on Warfarin Therapy
Macan, H. R., Uykimpang, R., Alconcel, M., Takasu, J., Razon, R. L., Amagase, H., & Niihara, Y. (2006) · Journal of Nutrition · doi:10.1093/jn/136.3.793s · Cited by 131
Effects of garlic on dyslipidemia in patients with type 2 diabetes mellitus.
Ashraf, R., Aamir, K., Shaikh, A. R., & Ahmed, T. (2005) · PubMed · Cited by 127
Kim, J. Y., & Kwon, O. (2008) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26142 · Cited by 123
Ried, K., Travica, N., & Sali, A. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2018.00122 · Cited by 120
Sobenin, I. A., Nedosugova, L. V., Filatova, L. V., Balabolkin, M. I., Gorchakova, T. V., & Orekhov, A. N. (2008) · Acta Diabetologica · doi:10.1007/s00592-007-0011-x · Cited by 119
Nantz, M. P., Rowe, C. A., Muller, C. E., Creasy, R. A., Stanilka, J. M., & Percival, S. S. (2012) · Clinical Nutrition · doi:10.1016/j.clnu.2011.11.019 · Cited by 117
Atkin, M., Laight, D. W., & Cummings, M. H. (2016) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2016.01.003 · Cited by 115
Sobenin, I. A., Pryanishnikov, V. V., Kunnova, L. M., Rabinovich, Y. A., Martirosyan, D. M., & Orekhov, A. N. (2010) · Lipids in Health and Disease · doi:10.1186/1476-511x-9-119 · Cited by 114
An intervention study to prevent gastric cancer by micro-selenium and large dose of allitridum.
Li, H., Li, H., Wang, Y., Xu, H.-X., Fan, W.-T., Wang, M., Sun, P., & Xie, X. (2004) · PubMed · Cited by 114
Leonarduzzi, G., Gamba, P., Gargiulo, S., Biasi, F., & Poli, G. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.09.031 · Cited by 113
Effects of garlic polysaccharide on alcoholic liver fibrosis and intestinal microflora in mice
Wang, Y., Guan, M., Zhao, X., & Li, X. (2018) · Pharmaceutical Biology · doi:10.1080/13880209.2018.1479868 · Cited by 110
Diretto, G., Rubio‐Moraga, Á., Argandoña, J., Castillo, P., Gómez‐Gómez, L., & Ahrazem, O. (2017) · Molecules · doi:10.3390/molecules22081359 · Cited by 108
Xu, C., Mathews, A., Rodrigues, C., Eudy, B. J., Rowe, C. A., O'Donoughue, A., & Percival, S. S. (2018) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2017.11.010 · Cited by 108
Kong, F., Lee, B. H., & Wei, K. (2019) · Molecules · doi:10.3390/molecules24020275 · Cited by 107
Jung, E., Park, S.-H., Choi, E., Ryu, B.-H., Park, B., Kim, D. S., Kim, Y.-G., & Chae, S. (2014) · Nutrition · doi:10.1016/j.nut.2014.02.014 · Cited by 104
In vivo metabolism of diallyl disulphide in the rat: identification of two new metabolites
Germain, E., Auger, J., Giniès, C., Siess, M. H., & Teyssier, C. (2002) · Xenobiotica · doi:10.1080/0049825021000017902 · Cited by 103
Dziri, S., Hassen, I. E., Fatnassi, S., M’Rabet, Y., Casabianca, H., Hanchi, B., & Hosni, K. (2012) · Journal of Functional Foods · doi:10.1016/j.jff.2012.01.010 · Cited by 102
Does Garlic Reduce Risk of Colorectal Cancer? A Systematic Review , ,3
Ngo, S. N. T., Williams, D. B., Cobiac, L., & Head, R. J. (2007) · Journal of Nutrition · doi:10.1093/jn/137.10.2264 · Cited by 100
Antimicrobial and antioxidant properties of various Greek garlic genotypes
Petropoulos, S. A., Fernandes, Â. S. F., Barros, L., Ćirić, A., Sokóvić, M., & Ferreira, I. C. F. R. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2017.10.078 · Cited by 96
Bakhshi, M., Taheri, J. B., Shabestari, S. B., Tanik, A., & Pahlevan, R. (2011) · Gerodontology · doi:10.1111/j.1741-2358.2011.00544.x · Cited by 94
Turner, B., Mølgaard, C., & Marckmann, P. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041255 · Cited by 94
Allium vegetables and stomach cancer risk in China.
Setiawan, V. W., Yu, G. P., Lu, Q., Lu, M.-L., Yu, S., Mu, L., Zhang, J., Kurtz, R. C., Cai, L., Hsieh, C., et al. (2005) · PubMed · Cited by 87
Self-citationAllicin disrupts the cell's electrochemical potential and induces apoptosis in yeast
Gruhlke, M. C. H., Portz, D., Stitz, M., Anwar, A., Schneider, T. L., Jacob, C., Schlaich, N. L., & Slusarenko, A. J. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.09.019 · Cited by 82
Effect of aged garlic extract on wound healing: A new frontier in wound management
Ejaz, S., Chekarova, I., Cho, J. W., Lee, S. Y., Ashraf, S., & Lim, C. W. (2009) · Drug and Chemical Toxicology · doi:10.1080/01480540902862236 · Cited by 82
The Global Burden of Diabetes: An Overview
Herman, W. H. (2016) · Springer eBooks · doi:10.1007/978-3-319-41559-8_1 · Cited by 82
Intralesional tuberculin for treatment of refractory warts
Kuş, S., Ergun, T., Gün, D., & Akin, O. (2005) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2004.01176.x · Cited by 81
Shabani, E., Sayemiri, K., & Mohammadpour, M. (2018) · Primary care diabetes · doi:10.1016/j.pcd.2018.07.007 · Cited by 77
Zeng, T., Guo, F., Zhang, C., Song, F., Zhao, X., & Xie, K. (2012) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.5557 · Cited by 75
Dehghani, S., Alipoor, E., Salimzadeh, A., Yaseri, M., Hosseini, M., Feinle‐Bisset, C., & Hosseinzadeh‐Attar, M. J. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.04.060 · Cited by 74
Johnson, S. M., & Horn, T. D. (2004) · PubMed · Cited by 71
Gómez-Arbeláez, D., Lahera, V., Oubiña, P., Valero‐Muñoz, M., Heras, N. D. L., Rodríguez, Y. A., Garcia, R. G., Camacho, P. A., & López-Jaramillo, P. A. (2013) · Mediators of Inflammation · doi:10.1155/2013/285795 · Cited by 70
Jiang, X., Zhu, X., Xu, H., Zhao, Z., Li, S., Li, S.-Z., Cai, J.-H., & Cao, J. (2017) · Acta Pharmacologica Sinica · doi:10.1038/aps.2016.176 · Cited by 70
Effect of Raw Crushed Garlic ( Allium sativum L.) on Components of Metabolic Syndrome
Choudhary, P. R., Jani, R. D., & Sharma, M. S. (2017) · Journal of Dietary Supplements · doi:10.1080/19390211.2017.1358233 · Cited by 69
Gao, X., Chen, Y., Chen, Z., Xue, Z., Jia, Y., Guo, Q., Ma, Q., Zhang, M., & Chen, H. (2019) · Food & Function · doi:10.1039/c9fo00236g · Cited by 69
Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects
van Doorn, M. B., Santo, S. M. E., Meijer, P., Kamerling, I. M., Schoemaker, R. C., Dirsch, V., Vollmar, A., Haffner, T., Gebhardt, R., Cohen, A. F., et al. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/84.6.1324 · Cited by 68
Matsumoto, S., Nakanishi, R., Li, D., Alani, A., Rezaeian, P., Prabhu, S., Abraham, J., Fahmy, M. A., Dailing, C., Flores, F. R., et al. (2016) · Journal of Nutrition · doi:10.3945/jn.114.202424 · Cited by 65
Anti-Atherosclerotic Effects of a Phytoestrogen-Rich Herbal Preparation in Postmenopausal Women
Myasoedova, V. A., Kirichenko, T. V., Melnichenko, A. А., Orekhova, V. A., Ravani, A. L., Poggio, P., Sobenin, I. A., Bobryshev, Y. V., & Orekhov, A. N. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17081318 · Cited by 65
Mechanisms of angiogenesis: Role of hydrogen sulphide
Wang, M., Cai, W., & Zhu, Y. (2010) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2010.05371.x · Cited by 62
Serrano, A., Ros, G., & Nieto, G. (2018) · Medicines · doi:10.3390/medicines5030076 · Cited by 62
Zuniga, K. E., Parma, D. L., Muñoz, E., Spaniol, M., Wargovich, M. J., & Ramírez, A. G. (2018) · Breast Cancer Research and Treatment · doi:10.1007/s10549-018-4982-9 · Cited by 59
Jin, Z.-Y., Wu, M., Han, R., Zhang, X., Wang, X.-S., Liu, A., Zhou, J., Lu, Q., Zhang, Z., & Zhao, J. (2013) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-13-0015 · Cited by 58
Melino, S., Leo, S., & Papajani, V. T. (2019) · Nutrients · doi:10.3390/nu11071581 · Cited by 58
Berginc, K., Milisav, I., & Kristl, A. (2010) · Drug Metabolism and Pharmacokinetics · doi:10.2133/dmpk.dmpk-10-rg-053 · Cited by 55
Charron, C. S., Dawson, H. D., Albaugh, G. P., Solverson, P. M., Vinyard, B. T., Solano-Aguilar, G. I., Molokin, A., & Novotny, J. A. (2015) · Journal of Nutrition · doi:10.3945/jn.115.215392 · Cited by 53
Antileishmanial and Immunomodulatory Activity of Allium sativum (Garlic)
Foroutan, M., Tappeh, K. H., & Khademvatan, S. (2015) · Journal of Evidence-Based Complementary & Alternative Medicine · doi:10.1177/2156587215623126 · Cited by 53
Szulińska, M., Kręgielska-Narożna, M., Świątek, J., Styś, P., Kuźnar-Kamińska, B., Jakubowski, H., Walkowiak, J., & Bogdański, P. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.03.131 · Cited by 53
Sahebkar, A., Serban, C., Ursoniu, S., & Banach, M. (2016) · Nutrition · doi:10.1016/j.nut.2015.06.009 · Cited by 52
Kiesel, V. A., & Stan, S. D. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.01.184 · Cited by 50
Nakasone, Y., Nakamura, Y., Yamamoto, T., & Yamaguchi, H. (2012) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2012.819 · Cited by 47
Aged garlic and cancer: A systematic review
Azadbakht, L., Miraghajani, M. S., Rafie, N., Hajianfar, H., & Larijani, B. A. (2018) · International Journal of Preventive Medicine · doi:10.4103/ijpvm.ijpvm_437_17 · Cited by 45
Zare, E., Alirezaei, A., Bakhtiyari, M., & Mansouri, A. (2019) · BMC Nephrology · doi:10.1186/s12882-019-1204-6 · Cited by 45
Anti-cancer activities of S-allylmercaptocysteine from aged garlic
Lv, Y., So, K., Wong, N.-K., & Xiao, J. (2019) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(19)30008-1 · Cited by 44
Kim, H.-N., Kang, S. G., Roh, Y. K., Choi, M.-K., & Song, S.-W. (2016) · European Journal of Nutrition · doi:10.1007/s00394-016-1318-6 · Cited by 44
Soleimani, D., Paknahad, Z., Askari, G., Iraj, B., & Feizi, A. (2016) · Advanced Biomedical Research · doi:10.4103/2277-9175.174962 · Cited by 43
Mofrad, M. D., Milajerdi, A., Koohdani, F., Surkan, P. J., & Azadbakht, L. (2019) · Journal of Nutrition · doi:10.1093/jn/nxy310 · Cited by 43
Moosavian, S. P., Arab, A., Paknahad, Z., & Moradi, S. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2020.102385 · Cited by 41
Effects of garlic oil on platelet aggregation: A double blind placebo controlled crossover study
Wojcikowski, K., Myers, S. P., & Brooks, L. O. (2007) · Platelets · doi:10.1080/09537100600800636 · Cited by 38
Orekhov, A. N. (2013) · Current Pharmaceutical Design · doi:10.2174/1381612811319330011 · Cited by 38
A mini review: garlic extract and vascular diseases
Zhu, Y., Anand, R., Geng, X., & Ding, Y. (2018) · Neurological Research · doi:10.1080/01616412.2018.1451269 · Cited by 38
Wlosinska, M., Nilsson, A., Hlebowicz, J., Malmsjö, M., Fakhro, M., & Lindstedt, S. (2019) · International Wound Journal · doi:10.1111/iwj.13220 · Cited by 36
McCrea, C. E., West, S. G., Kris‐Etherton, P. M., Lambert, J. D., Gaugler, T. L., Teeter, D. L., Sauder, K. A., Gu, Y., Glisan, S. L., & Skulas‐Ray, A. C. (2015) · Journal of Translational Medicine · doi:10.1186/s12967-014-0360-5 · Cited by 35
Liang, J., Li, H. R., Chen, Y., Zhang, C., Chen, D. G., Liang, Z. C., Shi, Y. Q., Zhang, L. L., Xin, L., & Zhao, D. B. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.03.024 · Cited by 35
Effects of garlic on blood glucose levels and HbA1c in patients with type 2 diabetes mellitus
Ashraf, R., Phil, M., Khan, R. A., & Ashraf, I. (2011) · Journal of Medicinal Plants Research · doi:10.5897/jmpr.9000523 · Cited by 33
Thakur, S., & Habib, R. (2017) · International Journal of Clinical Pediatric Dentistry · doi:10.5005/jp-journals-10005-1442 · Cited by 33
Zhang, S., Gu, Y., Wang, L., Zhang, Q., Liu, L., Lu, M. M., Meng, G., Yao, Z., Wu, H., Xia, Y., et al. (2019) · European Journal of Endocrinology · doi:10.1530/eje-19-0179 · Cited by 32
Lee, G.-Y., Lee, J. J., & Lee, S.-M. (2015) · Nutrition and Cancer · doi:10.1080/01635581.2015.1073754 · Cited by 31
Salimzadeh, A., Alipoor, E., Dehghani, S., Yaseri, M., Hosseini, M., Feinle‐Bisset, C., & Hosseinzadeh‐Attar, M. J. (2018) · International Journal of Clinical Practice · doi:10.1111/ijcp.13208 · Cited by 31
Gail, M. H., & You, W. (2006) · Journal of Nutrition · doi:10.1093/jn/136.3.813s · Cited by 30
Wu, X., Shi, J. C., Fang, W., Guo, X., Zhang, L., Liu, Y., & Li, Z. (2019) · Asia-Pacific Journal of Clinical Oncology · doi:10.1111/ajco.13133 · Cited by 30
Ohtani, M., & Nishimura, T. (2019) · Biomedical Reports · doi:10.3892/br.2019.1269 · Cited by 30
Mozaffari–Khosravi, H., Hesabgar, H.-A.-S., Owlia, M. B., Hadinedoushan, H., Barzegar, K., & Fllahzadeh, M. H. (2012) · Journal of Dietary Supplements · doi:10.3109/19390211.2012.726703 · Cited by 28
Garlic intake lowers fasting blood glucose: meta-analysis of randomized controlled trials.
Hou, L.-Q., Liu, Y.-H., & Zhang, Y. (2015) · PubMed · doi:10.6133/apjcn.2015.24.4.15 · Cited by 28
Mahdavi‐Roshan, M. (2017) · The Anatolian Journal of Cardiology · doi:10.14744/anatoljcardiol.2017.7669 · Cited by 28
Zeb, F., Safdar, M., Fatima, S., Khan, S., Alam, S., Muhammad, M., Ayesha, S., Habib, F., & Shakoor, H. (2018) · Pakistan Journal of Pharmaceutical Sciences · doi:10.36721/pjps/31/5/05.08.2018/4861/1935-1941 · Cited by 28
Comparison of the therapeutic effects of Garcin® and fluconazole on Candida vaginitis
Ebrahimy, F., Dolatian, M., Moatar, F., & Majd, H. A. (2015) · Singapore Medical Journal · doi:10.11622/smedj.2015153 · Cited by 27
Watson, C. J., Grando, D., Fairley, C. K., Chondros, P., Garland, S. M., Myers, S. P., & Pirotta, M. V. (2013) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.12518 · Cited by 27
Parham, M., Bagherzadeh, M., Asghari, M., Akbari, H., Hosseini, Z., Rafiee, M., & Vafaeimanesh, J. (2020) · Europe PMC (PubMed Central) · doi:10.22088/cjim.11.1.12 · Cited by 27
Ahmadian, F., Mozaffari–Khosravi, H., Azaraein, M. H., Faraji, R., & Reza, J. Z. (2017) · Electronic physician · doi:10.19082/5670 · Cited by 25
Lu, J., Cheng, B., Meng, Z., Fang, B., Li, T., Sun, M.-C., Liu, M., & Guan, S. (2018) · Life Sciences · doi:10.1016/j.lfs.2017.12.040 · Cited by 24
Dietary Patterns and Whole Plant Foods in Aging and Disease
Dreher, M. L. (2018) · Springer eBooks · doi:10.1007/978-3-319-59180-3 · Cited by 24
Ghorbani, A., Zarvandi, M., & Rakhshandeh, H. (2019) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530319666190206213420 · Cited by 24
Effects Of Raw Garlic (Allium Sativum ) On Hyperglycemia In Patients With Type 2 Diabetes Mellitus
Mirunalini, S., Krishnaveni, M., & Ambily, V. R. (2011) · Cited by 23
Zeb, I., Ahmadi, N., Flores, F. R., & Budoff, M. J. (2017) · Coronary Artery Disease · doi:10.1097/mca.0000000000000587 · Cited by 23
Andrianova, I. V., Sobenin, I. A., Середа, Е. В., Бородина, Л. И., & Студеникин, М. Я. (2003) · PubMed · Cited by 22
Said, M. M., Watson, C., & Grando, D. (2020) · Scientific Reports · doi:10.1038/s41598-020-60178-0 · Cited by 22
Kim, H.-N., Kang, S. G., Roh, Y. K., Choi, M.-K., & Song, S.-W. (2017) · European Journal of Nutrition · doi:10.1007/s00394-016-1362-2 · Cited by 21
Gökalp, F. (2018) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.22215 · Cited by 20
Gatt, M. E., Strahilevitz, J., Sharon, N. A., Lavie, D., Goldschmidt, N., Kalish, Y., Gural, A., & Paltiel, O. (2015) · Integrative Cancer Therapies · doi:10.1177/1534735415588928 · Cited by 19
Sujithra, K., Srinivasan, S., Indumathi, D., & Vinothkumar, V. (2018) · Toxicology Mechanisms and Methods · doi:10.1080/15376516.2018.1534297 · Cited by 19
Kenawy, S., Mohammed, G. F., Younes, S., & Elakhras, A. (2014) · Dermatologic Therapy · doi:10.1111/dth.12136 · Cited by 18
BACH1 mediates the antioxidant properties of aged garlic extract (Review)
Tsuneyoshi, T. (2019) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2019.8380 · Cited by 18
Serrano, H. D. A., Mariezcurrena-Berasain, M. A., Castillo, A. D. C. G., Valladares-Carranza, B., Pliego, A. B., Talavera-Rojas, M., Anele, U. Y., Salem, A. Z. M., & Rivas-Cáceres, R. R. (2020) · Microbial Pathogenesis · doi:10.1016/j.micpath.2020.104028 · Cited by 16
Panjeshahin, A., Mollahosseini, M., Panbehkar‐Jouybari, M., Kaviani, M., Mirzavandi, F., & Hosseinzadeh, M. (2020) · Phytotherapy Research · doi:10.1002/ptr.6659 · Cited by 16
Can garlic reduce risk of cancer?
Rivlin, R. S. (2008) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.27181 · Cited by 15
Kundaković, T., Milenković, M., Zlatković, S., Nikolić, V. D., Nikolić, G. S., & Binić, I. (2012) · Forschende Komplementärmedizin / Research in Complementary Medicine · doi:10.1159/000335786 · Cited by 13
Wang, Y., Zhang, L., Moslehi, R., Ma, J., Pan, K., Zhou, T., Liu, W., Brown, L. M., Hu, Y., Pee, D., et al. (2008) · Journal of Nutrition · doi:10.3945/jn.108.091389 · Cited by 13
Direct anti-atherosclerotic therapy
Orekhov, A. N. (2013) · Cited by 13
The effect of garlic powder on human urinary cytokine excretion.
Alma, E., Eken, A., Erçil, H., Yelsel, K., & Dağlıoğlu, N. (2014) · Urology journal./Urology jornal. · Cited by 11
Shafiekhani, M., Faridi, P., Kojuri, J., & Namazi, S. (2016) · PubMed Central · Cited by 11
Khoobkhahi, N., Delavar, R., & Nayebifar, S. (2019) · Science & Sports · doi:10.1016/j.scispo.2019.05.007 · Cited by 10
Lee, M. H., Kim, Y. M., & Kim, S. G. (2012) · International Journal of Clinical Pharmacology and Therapeutics · doi:10.5414/cp201746 · Cited by 9
Memon, A. R., Ghanghro, A. B., Shaikh, I. A., Qazi, N., Ghanghro, I. H., & Shaikh, U. (2018) · Journal of Liaquat University of Medical & Health Sciences · doi:10.22442/jlumhs.181720559 · Cited by 8
Antioxidant and antibacterial potentials of Aloe vera juice extract against wound isolates.
Ranjani, M., Rajan, S., & Brindha, P. (2010) · Journal of Pure and Applied Microbiology · Cited by 6
Samdani, A. J., Samreen, S., Choudhary, M. I., & Rahman, A. (2012) · Anti-Infective Agents · doi:10.2174/2211362611208020111 · Cited by 6
Impact of garlic tablets on nosocomial infections in hospitalized patients in intensive care units
Madineh, H., Yadollahi, F., Yadollahi, F., Mofrad, E. P., & Kabiri, M. (2017) · Electronic physician · doi:10.19082/4064 · Cited by 6
Garlic Extract as a Novel Addition to Antikeloid Armamentarium: An Untested Hypothesis
Feily, A., Namazi, M. R., Pazyar, N., Saboktakin, M., & Saboktakin, M. (2009) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2009.0255 · Cited by 5
Flagged first, then by citations
10 of the 156 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Londhe, 2011, Role of garlic (Allium sativum) in various diseases: An overview, Angiogenesis, 12, 13
- Varma, 2011, Potential clinical benefits of garlic (Allium sativum), J. Environ. Res. Dev., 5, 652
Cited by
Sorted by citations
Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials
Parham, S., Kharazi, A. Z., Bakhsheshi‐Rad, H. R., Nur, H., Ismail, A. F., Sharif, S., Ramakrishna, S., & Berto, F. (2020) · Antioxidants · doi:10.3390/antiox9121309 · Cited by 535
Anticancer potential of garlic and its bioactive constituents: A systematic and comprehensive review
Greef, D. D., Barton, E. M., Sandberg, E. N., Croley, C. R., Pumarol, J., Wong, T. L., Das, N., & Bishayee, A. (2020) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.11.020 · Cited by 170
Association between Oral Cancer and Diet: An Update
Rodríguez-Molinero, J., Migueláñez-Medrán, B. D. C., Puente-Gutiérrez, C., Delgado-Somolinos, E., Carreras‐Presas, C. M., Fernández-Farhall, J., & López‐Sánchez, A. F. (2021) · Nutrients · doi:10.3390/nu13041299 · Cited by 171
The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence
Varesi, A., Chirumbolo, S., Campagnoli, L. I. M., Pierella, E., Piccini, G. B., Carrara, A., Ricevuti, G., Scassellati, C., Bonvicini, C., & Pascale, A. (2022) · Antioxidants · doi:10.3390/antiox11071224 · Cited by 145
The role of natural antioxidants in cisplatin-induced hepatotoxicity
Rashid, N. A., Halim, S. A. S. A., Teoh, S. L., Budin, S. B., Hussan, F., Ridzuan, N. R. A., & Jalil, N. A. A. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112328 · Cited by 147
Metadata
- Authors
- Ansary, J., Forbes-Hernández, T. Y., Gil, E., Cianciosi, D., Zhang, J., Elexpuru-Zabaleta, M., Simal-Gandara, J., Giampieri, F., & Battino, M.
- Affiliations
- Marche Polytechnic University (IT)
- Universidade de Vigo (ES)
- Nutrition and Food Science Group, Department of Biochemistry, Genetics and Immunology, Faculty of Biology, University of Vigo, 36310 Vigo, Spain
- Dipartimento di Scienze Cliniche e Molecolari, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy
- Nutrition and Bromatology Group, Department of Analytical and Food Chemistry, Faculty of Science, University of Vigo, Ourense Campus, E-32004 Ourense, Spain
- Jiangsu University (CN)
- Corresponding author
- Giampieri, Francesca
- Battino, Maurizio
- ORCID
- Venue
- Antioxidants
- Publisher
- MDPI AG
- Published
- 2020-07-15
- Volume
- 9
- Issue
- 7
- Pages
- 619
- ISSN
- 2076-3921 (ISSN-L)
- PMC
- PMC7402177
- OpenAlex
- W3042652083
- Cited by
- 217
- References
- 156
- Citations by year
- 2026: 30 · 2025: 32 · 2024: 45 · 2023: 47 · 2022: 29 · 2021: 28 · 2020: 4
- FWCI
- 2.28
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Antioxidants (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Università Politecnica delle Marche (Università Politecnica delle Marche) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Investigo repository of University of Vigo (University of Vigo) (submittedVersion, other-oa)
- UNICA IRIS Institutional Research Information System (University of Cagliari) (submittedVersion, other-oa)
- Investigo Institutional repository of UVigo (Universidade de Vigo) (submittedVersion, cc-by)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Garlic and Onion Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics, phytochemicals, and oxidative stress
- Physical Sciences › Chemistry › Organic Chemistry › Chemical synthesis and alkaloids
- Keywords
- garlic, organosulfur compounds, polyphenols, nutraceuticals, garlic extract, oxidative stress, inflammation, cancer prevention, cardiovascular disease, metabolic disorders, diabetes mellitus, blood pressure, skin health, bone health, bioavailability, drug interactions, human intervention studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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