The mitochondrial permeability transition: Nexus of aging, disease and longevity

Rottenberg, Hagai, Hoek, Jan B.·2021·Cells

DOI 10.3390/cells10010079

Cites (320)

Items 201–299 of 299

Drp1 knockdown induces severe muscle atrophy and remodelling, mitochondrial dysfunction, autophagy impairment and denervation
Dulac, Maude, Leduc‐Gaudet, Jean‐Philippe, Reynaud, Olivier, Ayoub, Marie‐Belle, Guérin, Amanda, Finkelchtein, Michel, Hussain, Sabah NA, Gouspillou, Gilles · 2020 · The Journal of Physiology
Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity
Ma, Siming, Upneja, Akhil, Galecki, Andrzej, Tsai, Yi-Miau, Burant, Charles F, Raskind, Sasha, Zhang, Quanwei, Zhang, Zhengdong D, Seluanov, Andrei, Gorbunova, Vera et al. · 2016 · eLife
Resveratrol rescues cadmium-induced mitochondrial injury by enhancing transcriptional regulation of PGC-1α and SOD2 via the Sirt3/FoxO3a pathway in TCMK-1 cells
Beibei Fu, Jiamin Zhao, Wei Peng · 2017 · Biochemical and Biophysical Research Communications
Mitochondrial Complex I Inhibition by Metformin Limits Reperfusion Injury
Ahmed A. Mohsin, Qun Chen, Nanhu Quan, Thomas V. Rousselle, Michael W. Maceyka, Arun Samidurai, Jeremy Thompson, Ying Hu, Ji Li, Edward Joseph Lesnefsky · 2019 · Journal of Pharmacology and Experimental Therapeutics
The Mitochondrial Permeability Transition in Mitochondrial Disorders
Justina Šileikytė, Michael A. Forte · 2019 · Oxidative Medicine and Cellular Longevity
LRRK2 and α-Synuclein: Distinct or Synergistic Players in Parkinson’s Disease?
Darren M. O’Hara, Grishma N. Pawar, Suneil Kumar Kalia, Lorraine V. Kalia · 2020 · Frontiers in Neuroscience
Melatonin pretreatment enhances the therapeutic effects of exogenous mitochondria against hepatic ischemia–reperfusion injury in rats through suppression of mitochondrial permeability transition
Hong‐Hwa Chen, Yen‐Ta Chen, Chih‐Chao Yang, Kuan‐Hung Chen, Pei‐Hsun Sung, Hsin‐Ju Chiang, Chih‐Hung Chen, Sarah O. Chua, Sheng‐Ying Chung, Yi‐Ling Chen et al. · 2016 · Journal of Pineal Research
A 20/20 view of ANT function in mitochondrial biology and necrotic cell death
Bround, Michael J., Bers, Donald M., Molkentin, Jeffery D. · 2020 · Journal of Molecular and Cellular Cardiology
Two mechanisms by which ATP depletion potentiates induction of the mitochondrial permeability transition
Gabriella Simbula, Peter A. Glascott, S. Akita, Jan B. Hoek, J L Farber · 1997 · American Journal of Physiology-Cell Physiology
A mitochondrial delicacy: dynamin-related protein 1 and mitochondrial dynamics
Mason Breitzig, Matthew D. Alleyn, Richard F. Lockey, Narasaiah Kolliputi · 2018 · American Journal of Physiology-Cell Physiology
Aging is associated with a decline in Atg9b-mediated autophagosome formation and appearance of enlarged mitochondria in the heart
Liang, Wenjing, Moyzis, Alexandra G., Lampert, Mark A., Diao, Rachel Y., Najor, Rita H., Gustafsson, Åsa B. · 2020 · Aging Cell
Activation of transcription factor Nrf2 to counteract mitochondrial dysfunction in Parkinson's disease
Claudia Bento‐Pereira, Albena T. Dinkova‐Kostova · 2020 · Medicinal Research Reviews
Toward understanding genomic instability, mitochondrial dysfunction and aging
Fakouri, Nima B., Hou, Yujun, Demarest, Tyler G., Christiansen, Louise S., Okur, Mustafa N., Mohanty, Joy G., Croteau, Deborah L., Bohr, Vilhelm A. · 2019 · The FEBS Journal
Mitochondrial Perturbations Couple mTORC2 to Autophagy in C. elegans
Helena Aspernig, Thomas Heimbucher, Wenjing Qi, Dipak Gangurde, Sedric Curic, Yijian Yan, Erika Donner von Gromoff, Ralf Baumeister, Antje Thien · 2019 · Cell Reports
Aging shifts mitochondrial dynamics toward fission to promote germline stem cell loss.
Amartuvshin, Oyundari, Lin, Chi‐Hung, Hsu, Shao‐Chun, Kao, Shih‐Han, Chen, Alvin, Tang, Wei‐Chun, Chou, Han‐Lin, Chang, Dong‐Lin, Hsu, Yen‐Yang, Hsiao, Bai‐Shiou et al. · 2020 · Aging Cell
Oxidative Insults and Mitochondrial DNA Mutation Promote Enhanced Autophagy and Mitophagy Compromising Cell Viability in Pluripotent Cell Model of Mitochondrial Disease
Dar‐Shong Lin, Yu-Wen Huang, Che‐Sheng Ho, Pi‐Lien Hung, Mei‐Hsin Hsu, Tuan-Jen Wang, Tsu‐Yen Wu, Tsung‐Han Lee, Zo-Darr Huang, Po-Chun Chang et al. · 2019 · Cells
The role of the TOR pathway in mediating the link between nutrition and longevity
Lushchak, Oleh, Strilbytska, Olha, Piskovatska, Veronika, Storey, Kenneth B., Koliada, Alexander, Vaiserman, Alexander · 2017 · Mechanisms of Ageing and Development
NIM811, a cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models
Alessandra Zulian, E. Rizzo, Marco Schiavone, Elena Palma, Francesca Tagliavini, Bert Blaauw, Luciano Merlini, Nadir M. Maraldi, Patrizia Sabatelli, Paola Braghetta et al. · 2014 · Human Molecular Genetics
Exercise training induces respiratory substrate-specific decrease in Ca<sup>2+</sup>-induced permeability transition pore opening in heart mitochondria
Marcil, Mariannick, Bourduas, Karine, Ascah, Alexis, Burelle, Yan · 2006 · American Journal of Physiology-Heart and Circulatory Physiology
Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection
Carraro, Michela, Carrer, Andrea, Urbani, Andrea, Bernardi, Paolo · 2020 · Journal of Molecular and Cellular Cardiology
Restriction of mitochondrial calcium overload by mcu inactivation renders neuroprotective effect in Zebrafish models of Parkinson's disease
Smijin K. Soman, Michał A. Bazała, Marcus Keatinge, Oliver Bandmann, Jacek Kuźnicki · 2019 · Biology Open
Mechanisms of Autophagy in Metabolic Stress Response.
A. Gross, M. Graef · 2020 · Journal of Molecular Biology
Influence of aging on membrane permeability transition in brain mitochondria
Toman, Julia, Fiskum, Gary · 2011 · Journal of Bioenergetics and Biomembranes
Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming
Zhongfu Ying, Ge Xiang, Lingjun Zheng, Haite Tang, Lifan Duan, Xiaobing Lin, Qiuge Zhao, Keshi Chen, Yi Wu, Guangsuo Xing et al. · 2018 · Cell Metabolism
Dynamics of the mitochondrial permeability transition pore: Transient and permanent opening events
Boyman, Liron, Coleman, Andrew K., Zhao, Guiling, Wescott, Andrew P., Joca, Humberto C., Greiser, B. Maura, Karbowski, Mariusz, Ward, Chris W., Lederer, W.J. · 2019 · Archives of Biochemistry and Biophysics
The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production
Renata L. S. Gonçalves, Mark A. Watson, Hoi Shan Wong, Adam L. Orr, Martin D. Brand · 2019 · Redox Biology
Resveratrol Improves Bnip3-Related Mitophagy and Attenuates High-Fat-Induced Endothelial Dysfunction
Chen Li, Ying Tan, Jiandi Wu, Qinghui Ma, Shu-chang Bai, Zhangqing Xia, Xiaoliang Wan, Jianqiu Liang · 2020 · Frontiers in Cell and Developmental Biology
Endurance training reverts heart mitochondrial dysfunction.; permeability transition and apoptotic signaling in long-term severe hyperglycemia
Lumini-Oliveira, José, Magalhães, José, Pereira, Cláudia V., Moreira, Ana C., Oliveira, Paulo J., Ascensão, António · 2011 · Mitochondrion
A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling
Heide Christine Patterson, Carolin Gerbeth, Prathapan Thiru, F.‐Nora Vögtle, Marko Knoll, Aliakbar Shahsafaei, Kaitlin E. Samocha, Cher X. Huang, M. Michael Harden, Rui Song et al. · 2015 · Proceedings of the National Academy of Sciences
New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases
Fabio Di Lisa, Marco Giorgio, Péter Ferdinándy, Rainer Schulz · 2016 · British Journal of Pharmacology
Integrating the UPRmtinto the mitochondrial maintenance network
Christopher J. Fiorese, Cole M. Haynes · 2017 · Critical Reviews in Biochemistry and Molecular Biology
Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex II
Paavo Kôrge, Scott John, Guillaume Calmettes, James N. Weiss · 2017 · Journal of Biological Chemistry
Parkin, an E3 Ubiquitin Ligase, Plays an Essential Role in Mitochondrial Quality Control in Parkinson’s Disease
Xiaole Wang, Sitong Feng, Zhen‐Zhen Wang, Yu‐He Yuan, Nai‐Hong Chen, Yi Zhang · 2020 · Cellular and Molecular Neurobiology
3‐Nitropropionic acid induces autophagy by forming mitochondrial permeability transition pores rather than activatiing the mitochondrial fission pathway
María E. Solesio, Sara Sáez-Atiénzar, Joaquı́n Jordán, María Francisca Galindo · 2012 · British Journal of Pharmacology
Regulation of Ca2+ transport in brain mitochondria. I. The mechanism of spermine enhancement of Ca2+ uptake and retention
Rottenberg, Hagai, Marbach, Miriam · 1990 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability
Chuen‐Lin Huang, Chih-Chang Chao, Yi‐Chao Lee, Mei‐Kuang Lu, Jing‐Jy Cheng, Ying-Chen Yang, Vin-Chi Wang, Wen‐Chang Chang, Nai‐Kuei Huang · 2015 · Molecular Neurobiology
Agephagy – Adapting Autophagy for Health During Aging
Eleanor Rachel Stead, Jorge Iván Castillo-Quan, Victoria Eugenia Martinez-Miguel, Celia Lujan, Robin Ketteler, Kerri J. Kinghorn, Ivana Bjedov · 2019 · Frontiers in Cell and Developmental Biology
Dual dynamics of mitochondrial permeability transition pore opening
Benjamin Wacquier, Laurent Combettes, Geneviève Dupont · 2020 · Scientific Reports
Induction of the permeability transition pore in cells depleted of mitochondrial DNA
Ionica Masgras, Andrea Rasola, Paolo Bernardi · 2012 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Exercise enhances mitochondrial fission and mitophagy to improve myopathy following critical limb ischemia in elderly mice via the PGC1a/FNDC5/irisin pathway
Wuyang He, Peng Wang, Qingwei Chen, Chunqiu Li · 2020 · Skeletal Muscle
Volume changes in liver mitochondria.
Giovanni Felice AZZONE, Angelo Azzi · 1965 · Proceedings of the National Academy of Sciences
Changes in the mitochondrial permeability transition pore in aging and age-associated diseases
Giuseppe Paradies, Valeria Paradies, Francesca Maria Ruggiero, Giuseppe Petrosillo · 2012 · Mechanisms of Ageing and Development
Novel Insights into the Anti-Aging Role of Mitophagy
2018 · International Review of Cell and Molecular Biology
Effects of Physical Exercise on Autophagy and Apoptosis in Aged Brain: Human and Animal Studies
D. Andreotti, J. N. Silva, Amanda Midori Matumoto, A. Orellana, Paloma Segura De Mello, E. Kawamoto · 2020 · Frontiers in Nutrition
α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo
Victor S. Van Laar, Jianming Chen, Alevtina Zharikov, Qing Bai, Roberto Di Maio, April A. Dukes, Teresa G. Hastings, Simon C. Watkins, J. Timothy Greenamyre, Claudette M. St. Croix et al. · 2020 · Redox Biology
DNA damage responses in ageing
Paulo F. L. da Silva, Björn Schumacher · 2019 · Open Biology
Resveratrol protects cardiomyocytes against anoxia/reoxygenation via dephosphorylation of VDAC1 by Akt-GSK3 β pathway
Tian, Mengyuan, Xie, Yongyan, Meng, Yan, Ma, Wen, Tong, Zhihong, Yang, Xiaomei, Lai, Songqing, Zhou, Yue, He, Ming, Liao, Zhangping · 2019 · European Journal of Pharmacology
Melatonin preserves the transient mitochondrial permeability transition for protection during mitochondrial Ca2+stress in astrocyte
Mei‐Jie Jou · 2011 · Journal of Pineal Research
Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons
Macarena S. Arrázola, Eva Ramos‐Fernández, Pedro Cisternas, Daniela Ordenes, Nibaldo C. Inestrosa · 2017 · PLoS ONE
Dynamin-related protein 1 (Drp1) mediating mitophagy contributes to the pathophysiology of nervous system diseases and brain injury.
Qiong Wu, Cheng-Liang Luo, L. Tao · 2017 · Histology and Histopathology
Rapamycin Confers Neuroprotection Against Aging-Induced Oxidative Stress, Mitochondrial Dysfunction, and Neurodegeneration in Old Rats Through Activation of Autophagy
Abhishek Kumar Singh, Sandeep Singh, Vinay Tripathi, Akalabya Bissoyi, Geetika Garg, Syed Ibrahim Rizvi · 2018 · Rejuvenation Research
Multiple pathways for mitophagy: A neurodegenerative conundrum for Parkinson’s disease
Charleen T. Chu · 2018 · Neuroscience Letters
The P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration
Savino, Costanza, Pelicci, PierGiuseppe, Giorgio, Marco · 2013 · Oxidative Medicine and Cellular Longevity
Sirtuin 3 is required for the protective effect of Resveratrol on Manganese‐induced disruption of mitochondrial biogenesis in primary cultured neurons
Qian Sun, Run‐Run Kang, Kai‐Ge Chen · 2020 · Journal of Neurochemistry
NAD <sup>+</sup> : The convergence of DNA repair and mitophagy
Fang, Evandro F., Bohr, Vilhelm A. · 2017 · Autophagy
Genome instability: a conserved mechanism of ageing?
Jan Vijg, Xiao Dong, Brandon Milholland, Lei Zhang · 2017 · Essays in Biochemistry
Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition
Sergio L. Menezes‐Filho, Ignácio Amigo, Fernanda M. Prado, Natalie Chaves Cayuela, Márcia Kiyomi Koike, Isabella Fernanda Dantas Pinto, Sayuri Miyamoto, Edna Frasson de Souza Montero, Marisa Helena Gennari de Medeiros, Alicia Juliana Kowaltowski · 2017 · Free Radical Biology and Medicine
Metformin promotes mitophagy in mononuclear cells: a potential in vitro model for unraveling metformin's mechanism of action
Shipra Bhansali, Anil Bhansali, Veena Dhawan · 2019 · Annals of the New York Academy of Sciences
Synchronism in mitochondrial ROS flashes, membrane depolarization and calcium sparks in human carcinoma cells
Andrey V. Kuznetsov, Sabzali A. Javadov, Valdur A. Saks, Raimund Margreiter, Michael F. Grimm · 2017 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Current Progress of Mitochondrial Quality Control Pathways Underlying the Pathogenesis of Parkinson’s Disease
Xue Jiang, Tao Jin, Haining Zhang, Jing Miao, Xiuzhen Zhao, Yana Su, Ying Zhang · 2019 · Oxidative Medicine and Cellular Longevity
Maximizing Longevity and Healthspan: Multiple Approaches All Converging on Autophagy
Bareja, Akshay, Lee, David E., White, James P. · 2019 · Frontiers in Cell and Developmental Biology
PINK1-Parkin signaling in Parkinson’s disease: Lessons from Drosophila
Yuzuru Imai · 2020 · Neuroscience Research
The Ca2+-induced permeability transition pore is involved in Ca2+-induced mitochondrial oscillations
Yu. V. Evtodienko, Vera V. Teplova, Jahangir A. Khawaja, N-E. L. Saris · 1994 · Cell Calcium
Permeability Transition Pore-Mediated Mitochondrial Superoxide Flashes Regulate Cortical Neural Progenitor Differentiation
Hou, Yan, Mattson, Mark P., Cheng, Aiwu · 2013 · PLoS ONE
Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides
James J. Boslett, Moustafa Helal, Eduardo N. Chini, Jay Louis Zweier · 2018 · Journal of Molecular and Cellular Cardiology
Dependence of PINK1 accumulation on mitochondrial redox system
Feng Gao, Yan Zhang, Xiao‐Ou Hou, Zhouteng Tao, Haigang Ren, Guanghui Wang · 2020 · Aging Cell
Spermidine ameliorates liver ischaemia-reperfusion injury through the regulation of autophagy by the AMPK-mTOR-ULK1 signalling pathway
Liu, Hao, Dong, Jiayong, Song, Shaohua, Zhao, Yuanyu, Wang, Jiyuan, Fu, Zhiren, Yang, Jinghui · 2019 · Biochemical and Biophysical Research Communications
Compounds that extend longevity are protective in neurodegenerative diseases and provide a novel treatment strategy for these devastating disorders
Sonja K. Soo, Paige D. Rudich, Annika Traa, Namasthée Harris-Gauthier, Hazel J. Shields, Jeremy M. Van Raamsdonk · 2020 · Mechanisms of Ageing and Development
Mitochondrial Function, Dynamics, and Permeability Transition: A Complex Love Triangle as A Possible Target for the Treatment of Brain Aging and Alzheimer’s Disease
Carola Stockburger, Schamim H. Eckert, Gunter Peter Eckert, Kristina Friedland, Walter E. Müller · 2018 · Journal of Alzheimer s Disease
Dietary Restriction Augments Protection Against Induction of the Mitochondrial Permeability Transition
Bruce S. Kristal, Byung Pal Yu · 1998 · Free Radical Biology and Medicine
Autophagy-Sirt3 Axis Decelerates Hematopoietic Aging
Yixuan Fang, Ni A. An, Gaoyue Jiang, Lingjiang Zhu, Lei Li, Ruijin Zhao, Ye Yuan, Gaochuan Zhang, Xingyun Yao, Li Xu et al. · 2018 · Aging Cell
Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition
Andrea Guidarelli, Mara Fiorani, Liana Cerioni · 2017 · BioFactors
Autophagy, Aging, and Longevity
Li Luo, Zheng‐Hong Qin · 2019 · Advances in experimental medicine and biology
Exogenous spermine inhibits hypoxia/ischemia-induced myocardial apoptosis via regulation of mitochondrial permeability transition pore and associated pathways
Wei, Can, Li, Hongzhu, Wang, Yuehong, Peng, Xue, Shao, Hongjiang, Li, Hongxia, Bai, Shuzhi, Xu, Changqing · 2016 · Experimental Biology and Medicine
Proteostasis and ageing: insights from long‐lived mutant mice
William A. Sands, Melissa M. Page, Colin Selman · 2017 · The Journal of Physiology
Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III
Paavo Kôrge, Guillaume Calmettes, Scott John, James N. Weiss · 2017 · Journal of Biological Chemistry
Zn2+ and mPTP mediate resveratrol-induced myocardial protection from endoplasmic reticulum stress
He, Yifei, Fu, Yu, Xi, Mengyao, Zheng, Huan, Zhang, Yidong, Liu, Yulin, Zhao, Yang, Xi, Jinkun, He, Yonggui · 2020 · Metallomics
Differential Involvement of Mitochondrial Permeability Transition in Cytotoxicity of 1-Methyl-4-Phenylpyridinium and 6-Hydroxydopamine
Chung Soo Lee, Woo Jae Park, Hyun Hee Ko · 2006 · Molecular and Cellular Biochemistry
Manganese ions enhance mitochondrial H2O2 emission from Krebs cycle oxidoreductases by inducing permeability transition
Erik Bonke, Ilka Siebels, Klaus Zwicker, Stefan Dröse · 2016 · Free Radical Biology and Medicine
CoQ0-induced mitochondrial PTP opening triggers apoptosis via ROS-mediated VDAC1 upregulation in HL-60 leukemia cells and suppresses tumor growth in athymic nude mice/xenografted nude mice
You‐Cheng Hseu, Varadharajan Thiyagarajan, Ting‐Tsz Ou, Hsin‐Ling Yang · 2017 · Archives of Toxicology
Cyclophilin D Is Involved in the Regulation of Autophagy and Affects the Lifespan of P. anserina in Response to Mitochondrial Oxidative Stress
P. Kramer, Alexander T. Jung, Andréa Hamann, Heinz Dieter Osiewacz · 2016 · Frontiers in Genetics
Recent insights into the cellular and molecular determinants of aging
Linhao Ruan, Xi Zhang, Rong Li · 2018 · Journal of Cell Science
Poly-ADP-ribosylation signaling during DNA damage repair.
Barbara Golia, H. R. Singh, G. Timinszky · 2015 · Frontiers in Bioscience
Functional changes induced by caloric restriction in cardiac and skeletal muscle mitochondria
Julian D. C. Serna, Camille C. Caldeira da Silva, Alicia Juliana Kowaltowski · 2020 · Journal of Bioenergetics and Biomembranes
TORC2-SGK-1 signaling integrates external signals to regulate autophagic turnover of mitochondria via mtROS
Thomas Heimbucher, Wenjing Qi, Ralf Baumeister · 2020 · Autophagy
Exploiting the role of resveratrol in rat mitochondrial permeability transition
Zhang, Yue, Tian, Fangfang, Xiao, Qi, Hu, Yanjun, Li, Jiahan, Jiang, Fenglei, Liu, Yi · 2013 · The Journal of Membrane Biology
Mitochondrial aquaporin-8 is involved in SREBP-controlled hepatocyte cholesterol biosynthesis
Mauro Danielli, Julieta Marrone, Alejo M. Capiglioni, Raúl A. Marinelli · 2018 · Free Radical Biology and Medicine
The cyclophilin D/Drp1 axis regulates mitochondrial fission contributing to oxidative stress-induced mitochondrial dysfunctions in SH-SY5Y cells
Anqi Xiao, Xueqi Gan, Ruiqi Chen, Yanming Ren, Haiyang Yu, Chao You · 2016 · Biochemical and Biophysical Research Communications
Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway
J. Logan Bowling, Mary Catherine Skolfield, Wesley A. Riley, Andrew P. Nolin, Larissa C. Wolf, David E. Nelson · 2019 · BMC Molecular and Cell Biology
Modelling the p53/p66Shc Aging Pathway in the Shortest Living Vertebrate Nothobranchius Furzeri
Priami, Chiara, De Michele, Giulia, Cotelli, Franco, Cellerino, Alessandro, Giorgio, Marco, Pelicci, Pier Giuseppe, Migliaccio, Enrica · 2015 · Aging and Disease
Creatine Protects Against Cytosolic Calcium Dysregulation, Mitochondrial Depolarization and Increase of Reactive Oxygen Species Production in Rotenone-Induced Cell Death of Cerebellar Granule Neurons
Sofia Fortalezas, Dorinda Marques‐da‐Silva, Carlos Gutiérrez‐Merino · 2018 · Neurotoxicity Research
Recent advances in understanding the mechanisms determining longevity
Bayersdorf, Robert, Schumacher, Björn · 2019 · F1000Research
Permeability transition pore-dependent and PARP-mediated depletion of neuronal pyridine nucleotides during anoxia and glucose deprivation
Sibel Kahraman, Alex Siegel, Brian M. Polster, Gary M. Fiskum · 2014 · Journal of Bioenergetics and Biomembranes
Synthetic Ubiquinones Specifically Bind to Mitochondrial Voltage-Dependent Anion Channel 1 (VDAC1) in Saccharomyces cerevisiae Mitochondria
Masatoshi Murai, Ayaka Okuda, Takenori Yamamoto, Yasuo Shinohara, Hideto Miyoshi · 2017 · Biochemistry
AMPK mediates inhibition of electrolyte transport and NKCC1 activity by reactive oxygen species
Stephanie J. King, Michael Bunz, Alfred E. Chappell, Michael M. Scharl, Michael J. Docherty, Barbara Jung, Christian Y. Lytle, Declan F. McCole · 2019 · American Journal of Physiology-Gastrointestinal and Liver Physiology
The mitochondrial permeability transition pore: Is it formed by the ATP synthase.; adenine nucleotide translocators or both?
Baines, Christopher P., Gutiérrez-Aguilar, Manuel · 2020 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Dual role of polyamines in heart ischemia/reperfusion injury through regulation of mitochondrial permeability transition pore.
Huiying Chen, Xiaoli Jia, Shuqin Zhao · 2019 · PubMed
Dynamic modulation of autophagy: implications for aging and cancer
Liam D. Cassidy, Masashi Narita · 2020 · Molecular & Cellular Oncology
Genome instability: A conserved mechanism of aging?
Jan Vijg · 2017 · Experimental Gerontology