Antioxidant marine products in cancer chemoprevention
Abstract
SIGNIFICANCE: Oxidative stress resulting from excessive reactive oxygen/nitrogen/electrophilic species (ROS/RNS/RES) can lead to diseases such as cancer. The health benefits of dietary fruits and vegetables with antioxidant potential have received a great deal of attention. On the other hand, marine botanicals have been less well characterized and still remain as terra incognita. RECENT ADVANCES: In some parts of the world, appreciable quantities of seaweeds are consumed on a daily basis. Along with current globalization, cuisines using seaweeds are now being used throughout the world, sometimes considered as healthy delicacies. Thus, it is relevant to explore the medicinal and pharmacological properties of seaweeds, as well as the health ramifications of this dietary practice. CRITICAL ISSUES: We currently review the antioxidant potential of seaweed components such as sulfated polysaccharides, phenolic compounds (phlorotannins and bromophenols), and fucoxanthins. In addition to seaweeds, the chemistry and antioxidant activities of some marine fungi and bacteria are described. Since antioxidants are considered promising cancer chemopreventive agents, the in vitro, in vivo, and clinical aspects of antioxidant marine products are presented, and potential implications are discussed. FUTURE DIRECTIONS: Although some data suggest that health benefits are derived from the consumption of marine natural products, further epidemiological or clinical studies are needed to strengthen these observations. In addition, many studies have demonstrated the antioxidant effects of seaweeds with in vitro models, but further characterization of bioavailability is necessary to suggest the significance of these responses. It is also important to define the safety of some seaweeds containing inorganic arsenics.
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All these activities are usually associated with anticancer and cancer preventive properties.
“All these activities are usually associated with anticancer and cancer preventive properties.”
From Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects (2013) · cites this paper as [122]
Oxidative stress can lead to cancer and some antioxidant marine products proved to be chemopreventive antitumor agents.
“For example, it is known that oxidative stress can lead to cancer and some antioxidant marine products proved to be chemopreventive antitumor agents [122].”
From Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects (2013) · cites this paper as [122]
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- Authors
- Park, E.-J., & Pezzuto, J. M.
- Affiliations
- University of Hawaii at Hilo (US)
- Venue
- Antioxidants & Redox Signaling
- Publisher
- SAGE Publications
- Published
- 2013-07-10
- Volume
- 19
- Issue
- 2
- Pages
- 115-138
- ISSN
- 1523-0864 (ISSN-L)
- 1557-7716
- OpenAlex
- W1987618687
- Cited by
- 49
- References
- 152
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 6 · 2020: 4 · 2019: 6 · 2017: 6 · 2016: 6 · 2015: 4 · 2014: 4 · 2013: 3
- FWCI
- 0.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Antioxidants and Redox Signaling (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Echinoderm biology and ecology
- Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
- Keywords
- seaweed, antioxidant activity, chemoprevention, oxidative stress, sulfated polysaccharides, phlorotannins, bromophenols, fucoxanthin, marine fungi, marine bacteria, reactive oxygen species, reactive nitrogen species, inorganic arsenic, bioavailability
- MeSH terms
- Animals, Antioxidants, Biological Factors, Humans, Neoplasms, Anticarcinogenic Agents, Oxidative Stress, Chemoprevention, Aquatic Organisms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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