The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Potential Anti-Atherosclerotic Properties of Astaxanthin
Open accessAbstract
Astaxanthin is a naturally occurring red carotenoid pigment classified as a xanthophyll, found in microalgae and seafood such as salmon, trout, and shrimp. This review focuses on astaxanthin as a bioactive compound and outlines the evidence associated with its potential role in the prevention of atherosclerosis. Astaxanthin has a unique molecular structure that is responsible for its powerful antioxidant activities by quenching singlet oxygen and scavenging free radicals. Astaxanthin has been reported to inhibit low-density lipoprotein (LDL) oxidation and to increase high-density lipoprotein (HDL)-cholesterol and adiponectin levels in clinical studies. Accumulating evidence suggests that astaxanthin could exert preventive actions against atherosclerotic cardiovascular disease (CVD) via its potential to improve oxidative stress, inflammation, lipid metabolism, and glucose metabolism. In addition to identifying mechanisms of astaxanthin bioactivity by basic research, much more epidemiological and clinical evidence linking reduced CVD risk with dietary astaxanthin intake is needed.
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Increased oxidative stress in obesity and its impact on metabolic syndrome
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., & Shimomura, I. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21625 · Cited by 5,508
Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., et al. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6943 · Cited by 3,999
Haematococcus astaxanthin: applications for human health and nutrition
Guerin, M., Huntley, M. E., & Olaizola, M. (2003) · Trends in Biotechnology · doi:10.1016/s0167-7799(03)00078-7 · Cited by 1,495
Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae
Yuan, J., Peng, J., Yin, K., & Wang, J. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201000414 · Cited by 649
Boden, G., Duan, X., Homko, C., Molina, E. J., Song, W., Perez, O., Cheung, P., & Merali, S. (2008) · Diabetes · doi:10.2337/db08-0604 · Cited by 468
Abidov, M., Ramazanov, Z., Seifulla, R., & Grachev, S. (2010) · Diabetes, Obesity and Metabolism · doi:10.1111/j.1463-1326.2009.01132.x · Cited by 278
Yoshida, H., Yanai, H., Ito, K., Tomono, Y., Koikeda, T., Tsukahara, H., & Tada, N. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.10.012 · Cited by 269
Self-citationEffects of astaxanthin in obese mice fed a high-fat diet
IKEUCHI, M., KOYAMA, T., TAKAHASHI, J., & YAZAWA, K. (2007) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.60521 · Cited by 222
OKADA, Y., ISHIKURA, M., & MAOKA, T. (2009) · Bioscience, Biotechnology, and Biochemistry · doi:10.1271/bbb.90078 · Cited by 94 · cited 2×
“It is also noteworthy that the bioavailability of astaxanthin is decreased in smokers by approximately 40% [8].”
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Cited by
Yanai, H., & Yoshida, H. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20051190 · Cited by 468
Self-citationIndustrial potential of carotenoid pigments from microalgae: Current trends and future prospects
Ambati, R. R., Gogisetty, D., Aswathanarayana, R. G., Ravi, S., Bikkina, P. N., Bo, L., & Yuepeng, S. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1432561 · Cited by 372
Trends in use, pharmacology, and clinical applications of emerging herbal nutraceuticals
Williamson, E. M., Liu, X., & Izzo, A. A. (2020) · British Journal of Pharmacology · doi:10.1111/bph.14943 · Cited by 304
Lipids from Microalgae for Cosmetic Applications
De Luca, M., Pappalardo, I., Limongi, A. R., Viviano, E., Radice, R. P., Todisco, S., Martelli, G., Infantino, V., & Vassallo, A. (2021) · Cosmetics · doi:10.3390/cosmetics8020052 · Cited by 147
Preventive effect of dietary astaxanthin on UVA-induced skin photoaging in hairless mice
Komatsu, T., Sasaki, S., Manabe, Y., Hirata, T., & Sugawara, T. (2017) · PLOS ONE · doi:10.1371/journal.pone.0171178 · Cited by 109
Metadata
- Authors
- Kishimoto, Y., Yoshida, H., & Kondo, K.
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2016-02-05
- Volume
- 14
- Issue
- 2
- Pages
- 35
- ISSN
- 1660-3397 (ISSN-L)
- OpenAlex
- W2254236096
- Cited by
- 221
- References
- 9
- FWCI
- 9.20
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
