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Antibacterial and Antioxidant Activity of Essential Oil Terpenes against Pathogenic and Spoilage-Forming Bacteria and Cell Structure-Activity Relationships Evaluated by SEM Microscopy
Open accessAbstract
The antibacterial activity and antioxidant effect of the compounds α-terpineol, linalool, eucalyptol and α-pinene obtained from essential oils (EOs), against pathogenic and spoilage forming bacteria were determined. The antibacterial activities of these compounds were observed in vitro on four Gram-negative and three Gram-positive strains. S. putrefaciens was the most resistant bacteria to all tested components, with MIC values of 2% or higher, whereas E. coli O157:H7 was the most sensitive strain among the tested bacteria. Eucalyptol extended the lag phase of S. Typhimurium, E. coli O157:H7 and S. aureus at the concentrations of 0.7%, 0.6% and 1%, respectively. In vitro cell growth experiments showed the tested compounds had toxic effects on all bacterial species with different level of potency. Synergistic and additive effects were observed at least one dose pair of combination against S. Typhimurium, E. coli O157:H7 and S. aureus, however antagonistic effects were not found in these combinations. The results of this first study are encouraging for further investigations on mechanisms of antimicrobial activity of these EO components.
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“The potential effect of EO on rumen fermentation and methanogenesis is mainly mediated by their antimicrobial activities owing to their interaction with cell membranes of microbes (by disrupting membrane stability of lipid bilayer).”
From Phytogenic Additives Can Modulate Rumen Microbiome to Mediate Fermentation Kinetics and Methanogenesis Through Exploiting Diet–Microbe Interaction (2020) · cites this paper as [232]
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“They are most effective against gram +ve bacteria and possess almost no activity against gram –ve (because of their hydrophilic bilayer) except thymol and carvacrol (232).”
From Phytogenic Additives Can Modulate Rumen Microbiome to Mediate Fermentation Kinetics and Methanogenesis Through Exploiting Diet–Microbe Interaction (2020) · cites this paper as [232]
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Metadata
- Authors
- Zengin, H., & Baysal, A.
- Affiliations
- Izmir Institute of Technology (TR)
- Department of Food Engineering, Izmir Institute of Technology, Urla, Izmir 35437, Turkey
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2014-11-03
- Volume
- 19
- Issue
- 11
- Pages
- 17773-17798
- ISSN
- 1420-3049 (ISSN-L)
- PMC
- PMC6272013
- OpenAlex
- W1966480046
- Cited by
- 519
- References
- 65
- Citations by year
- 2026: 31 · 2025: 54 · 2024: 56 · 2023: 59 · 2022: 50 · 2021: 43 · 2020: 72 · 2019: 55 · 2018: 42 · 2017: 30 · 2016: 19 · 2015: 8
- FWCI
- 27.24
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Molecules (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- IYTE GCRIS Database (Izmir Institute of Technology) (submittedVersion, other-oa)
- İYTE (İZMİR YÜKSEK TEKNOLOJİ ENSTİTÜSÜ) (submittedVersion, other-oa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antimicrobial agents and applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Insect Pest Control Strategies
- Keywords
- antibacterial activity, antioxidant activity, α-terpineol, linalool, 1,8-cineole, α-pinene, pathogenic bacteria, synergistic and additive effects, Salmonella typhimurium, Escherichia coli O157:H7, Staphylococcus aureus, minimum inhibitory concentration, bacterial growth inhibition
- MeSH terms
- Eucalyptol, Acyclic Monoterpenes, Cyclohexane Monoterpenes, Bicyclic Monoterpenes, Anti-Bacterial Agents, Antioxidants, Bacteria, Cyclohexanols, Microscopy, Electron, Scanning, Oils, Volatile, Structure-Activity Relationship, Terpenes, Monoterpenes, Cyclohexenes
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