The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
DHA Effects in Brain Development and Function
Open accessAbstract
Docosahexaenoic acid (DHA) is a structural constituent of membranes specifically in the central nervous system. Its accumulation in the fetal brain takes place mainly during the last trimester of pregnancy and continues at very high rates up to the end of the second year of life. Since the endogenous formation of DHA seems to be relatively low, DHA intake may contribute to optimal conditions for brain development. We performed a narrative review on research on the associations between DHA levels and brain development and function throughout the lifespan. Data from cell and animal studies justify the indication of DHA in relation to brain function for neuronal cell growth and differentiation as well as in relation to neuronal signaling. Most data from human studies concern the contribution of DHA to optimal visual acuity development. Accumulating data indicate that DHA may have effects on the brain in infancy, and recent studies indicate that the effect of DHA may depend on gender and genotype of genes involved in the endogenous synthesis of DHA. While DHA levels may affect early development, potential effects are also increasingly recognized during childhood and adult life, suggesting a role of DHA in cognitive decline and in relation to major psychiatric disorders.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cross-national epidemiology of major depression and bipolar disorder
Weissman, M. M. (1996) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1996.03540040037030 · Cited by 2,302
Amminger, G. P., Schäfer, M. R., Papageorgiou, K., Klier, C. M., Cotton, S. M., Harrigan, S. M., Mackinnon, A., McGorry, P. D., & Berger, G. E. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.192 · Cited by 896
Makrides, M., Gibson, R. A., McPhee, A. J., Yelland, L., Quinlivan, J., Ryan, P., & DOMInO Investigative Team, A. T. (2010) · JAMA · doi:10.1001/jama.2010.1507 · Cited by 559
Bazan, N. G., Molina, M. F., & Gordon, W. C. (2011) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.012809.104635 · Cited by 441
Stonehouse, W., Conlon, C. A., Podd, J., Hill, S. R., Minihane, A. M., Haskell, C., & Kennedy, D. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.053371 · Cited by 252
Astarita, G., Jung, K.-M., Berchtold, N. C., Nguyen, V. Q., Gillen, D. L., Head, E., Cotman, C. W., & Piomelli, D. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012538 · Cited by 218
Cited by
Vitamin D and the athlete: current perspectives and new challenges
Owens, D. J., Allison, R., & Close, G. L. (2018) · Sports Medicine · doi:10.1007/s40279-017-0841-9 · Cited by 223
The clinical relevance of omega-3 fatty acids in the management of hypertriglyceridemia
Backes, J., Anzalone, D., Hilleman, D., & Catini, J. (2016) · Lipids in Health and Disease · doi:10.1186/s12944-016-0286-4 · Cited by 195
Microalgae as Sources of Omega-3 Polyunsaturated Fatty Acids: Biotechnological Aspects
Barta, D. G., Coman, V., & Vodnar, D. C. (2021) · Algal Research · doi:10.1016/j.algal.2021.102410 · Cited by 178
Clemens, V., von Hirschhausen, E., & Fegert, J. M. (2022) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-020-01615-3 · Cited by 147
Díaz, M., Mesa-Herrera, F., & Marín, R. (2021) · Antioxidants · doi:10.3390/antiox10060907 · Cited by 84
Metadata
- Authors
- Lauritzen, L., Brambilla, P., Mazzocchi, A., Harsløf, L., Ciappolino, V., & Agostoni, C.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2016-01-04
- Volume
- 8
- Issue
- 1
- Pages
- 6
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W2206567631
- Cited by
- 558
- References
- 6
- FWCI
- 38.98
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: DHA Effects in Brain Development and Function. https://app.cochat.ai/papers/10.3390/nu8010006
- The paper
- Lauritzen, L., Brambilla, P., Mazzocchi, A., Harsløf, L., Ciappolino, V., & Agostoni, C. (2016). DHA Effects in Brain Development and Function. Nutrients. https://doi.org/10.3390/nu8010006
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
