Biological Significance of Ascorbic Acid (Vitamin C) in Human Health - A Review
Open accessAbstract
The recognition of vitamin C (Ascorbic acid) is associated with history of an unrelenting search for the cause of the ancient hemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential for the development and maintenance of connective tissues. It plays an important role in bone formation, wound healing and the maintenance of healthy gums. Vitamin C plays an important role in a number of metabolic functions including the activation of the B vitamin, folic acid, the conversion of cholesterol to bile acids and the conversion of the amino acid, tryptophan, to the neurotransmitter, serotonin. It is an antioxidant that protects body from free radicals` damages. It is used as therapeutic agent in many diseases and disorders. Vitamin C protects the immune system, reduces the severity of allergic reactions and helps fight off infections.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Vitamin C protects against damage from reactive oxygen species.
“Vitamin C is crucial for immune system function [1,2,3,4] and protects against damage from reactive oxygen species [5,6].”
From Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults (2025) · cites this paper as [5]
Adequate cell and tissue stores of vitamin C maintain resistance to infections.
“Consequently, adequate cell and tissue stores of vitamin C maintain resistance to infections [5].”
From Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults (2025) · cites this paper as [5]
Cites
Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance
Levine, M., Conry-Cantilena, C., Wang, Y., Welch, R. W., Washko, P. W., Dhariwal, K. R., Park, J. B., Lazarev, A., Graumlich, J. F., King, J., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.8.3704 · Cited by 1,325 · cited 2× · see citing works
“…severity of illnesses (Hemila, 1992). breast, cervix, colon, rectum, esophagus, larynx, lung, Gaby and Singh (1991) reports that in 1981, in one mouth, prostate and stomach (Levine, 1996; Block, study, when 1 g of vitamin C was given intravenously to 1992; Frei, 1994; Block, 1991; Jacobs, 1993).”
BackgroundVitamins E and C, beta-carotene, and other carotenoids as antioxidants
Sies, H., & Stahl, W. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.6.1315s · Cited by 1,075 · cited 2× · see citing works
“radicals released by the body in its fight against the Vitamin C has been shown to improve the effects of infection (Sies and Wilhelm, 1995).”
BackgroundThe Framingham Eye Study. I. Outline and major prevalence findings.
Kahn, H. A., Leibowitz, H., Ganley, J., Kini, M., Colton, T., Nickerson, R. S., & Dawber, T. (1977) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112428 · Cited by 821 · see citing works
Ascorbic acid protects against endogenous oxidative DNA damage in human sperm.
Fraga, C., Motchnik, P., Shigenaga, M., Helbock, H., Jacob, R., & Ames, B. (1991) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.88.24.11003 · Cited by 809 · see citing works
Davidson, S. (1969) · The American Journal of the Medical Sciences · doi:10.1097/00000441-196711000-00023 · Cited by 746 · see citing works
Estimation of available dietary iron.
Monsen, E., Hallberg, L., Layrisse, M., Hegsted, D., Cook, J., Mertz, W., & Finch, C. (1978) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/31.1.134 · Cited by 603 · see citing works
Ascorbic Acid Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease
Levine, G. N., Frei, B., Koulouris, S. N., Gerhard, M. D., Keaney, J. F., & Vita, J. A. (1996) · Circulation · doi:10.1161/01.cir.93.6.1107 · Cited by 582 · cited 4× · see citing works
“…severity of illnesses (Hemila, 1992). breast, cervix, colon, rectum, esophagus, larynx, lung, Gaby and Singh (1991) reports that in 1981, in one mouth, prostate and stomach (Levine, 1996; Block, study, when 1 g of vitamin C was given intravenously to 1992; Frei, 1994; Block, 1991; Jacobs, 1993).”
BackgroundInfluentialVitamin C Intake and Mortality among a Sample of the United States Population
Enstrom, J., Kanim, L., & Klein, M. A. (1992) · Epidemiology · doi:10.1097/00001648-199205000-00003 · Cited by 580 · cited 1× · see citing works
“(Enstrom, 1992).”
Antioxidant Vitamin C Improves Endothelial Dysfunction in Chronic Smokers
Heitzer, T., Just, H., & Mu¨nzel, T. (1996) · Circulation · doi:10.1161/01.cir.94.1.6 · Cited by 554 · cited 1× · see citing works
“…(white blood defense against free radicals, athletes who are doing cells) to the lining of blood vessels and thereby reduce intense training may benefit from the addition of the risk of atherosclerosis (Weber, 1996; Lehr, 1995; antioxidant supplements to their diets (Dekkers et al., Heitzer, 1996).”
BackgroundReactive oxygen species and antioxidant vitamins: Mechanisms of action
Frei, B. B. (1994) · The American Journal of Medicine · doi:10.1016/0002-9343(94)90292-5 · Cited by 529 · cited 2× · see citing works
“…severity of illnesses (Hemila, 1992). breast, cervix, colon, rectum, esophagus, larynx, lung, Gaby and Singh (1991) reports that in 1981, in one mouth, prostate and stomach (Levine, 1996; Block, study, when 1 g of vitamin C was given intravenously to 1992; Frei, 1994; Block, 1991; Jacobs, 1993).”
BackgroundThe data support a role for antioxidants in reducing cancer risk.
Block, G. (2009) · Nutrition reviews · doi:10.1111/j.1753-4887.1992.tb01329.x · Cited by 351 · see citing works
Ascorbic acid protects lipids in human plasma and low-density lipoprotein against oxidative damage.
Frei, B. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/54.6.1113s · Cited by 326 · cited 1× · see citing works
“Vitamin C may to help protect the body against Low Density Lipoprotein provide podiatrists with a supplemental or alternative (LDL) cholesterol (Frei, 1991).”
BackgroundVitamin C and risk of death from stroke and coronary heart disease in cohort of elderly people
Gale, C., Martyn, C., Winter, P., & Cooper, C. (1995) · British medical journal · doi:10.1136/bmj.310.6994.1563 · Cited by 316 · cited 1× · see citing works
“A against stroke and heart attack (Gale, 1995; Wood diet rich in antioxidants (Vitamin E and Vitamin C House et al., 1994; Sahyoun, 1996).”
BackgroundThe Role of Antioxidant Vitamins and Enzymes in the Prevention of Exercise-Induced Muscle Damage
Dekkers, J., van Doornen, L., & Kemper, H. C. G. (1996) · Sports Medicine · doi:10.2165/00007256-199621030-00005 · Cited by 314 · see citing works
Nutrient intake and cataract extraction in women: a prospective study.
Hankinson, S. E., Stampfer, M. J., Seddon, J. M., Colditz, G. A., ROSNER, B. A., Speizer, F. E., & Willett, W. C. (1992) · BMJ · doi:10.1136/bmj.305.6849.335 · Cited by 312 · cited 2× · see citing works
“9 (Hankinson, 1992), some very recent works has shown cells such as phagocytes and neutrophills (Kronhausen that open angle glaucoma can be reversed by et al.”
BackgroundNuclear cataract and myopia during hyperbaric oxygen therapy.
Palmquist, B. ‐., Philipson, B., & Barr, P. (1984) · British Journal of Ophthalmology · doi:10.1136/bjo.68.2.113 · Cited by 290 · see citing works
Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein.
Jialal, I., Vega, G., & Grundy, S. (1990) · Atherosclerosis · doi:10.1016/0021-9150(90)90039-l · Cited by 285 · see citing works
Epidemiologic evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention
Jacques, P. F., & Chylack, L. T. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/53.1.352s · Cited by 261 · cited 1× · see citing works
“If the decrease the likelihood of developing cataracts association between low SAA levels and all-cause (Jacques et al., 1988). mortality is causal, increasing the consumption of Vitamin C reduces elevated pressure in the eye due to ascorbic acid and thereby SAA levels, can decrease the glaucoma…”
BackgroundEffect of ascorbic acid supplementation on the sperm quality of smokers.
Dawson, E. B., Harris, W. A., Teter, M. C., & Powell, L. C. (1992) · Fertility and Sterility · doi:10.1016/s0015-0282(16)55456-9 · Cited by 246 · cited 1× · see citing works
“It prevents et al., 1991), improves sperm quality in smokers harmful genetic alterations with in cells and protects (Dawson et al., 1992) and is effective in treating sperm lymphocytes from mutations to the chromosomes (Gaby agglutination, a condition, which causes sperm to stick and Singh, 1991).…”
BackgroundRecommended dietary intakes (RDI) of vitamin K in humans
Ja, O. (1987) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/45.4.687 · Cited by 236 · see citing works
Selected micronutrient intake and the risk of colorectal cancer.
Ferraroni, M., la Vecchia, C., D'Avanzo, B., Negri, E., Franceschi, S., & Decarli, A. (1994) · British Journal of Cancer · doi:10.1038/bjc.1994.463 · Cited by 227 · cited 1× · see citing works
“Growth in colon cancer and a vitamin C intake of the unsupplemented control subjects were infected, more than 157 mg/d has been found to reduce the risk when exposed to E. coli challenge infection (Gross and of developing colon cancer by 50% (Ferraroni, 1994; Cherry, 1988).”
BackgroundMalins, D. C., Polissar, N. L., & Gunselman, S. J. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.6.2557 · Cited by 222 · cited 1× · see citing works
“Meanwhile a study of chickens showed that vitamin C (Malins, 1996).”
BackgroundSteady-state turnover and body pool of ascorbic acid in man.
Kallner, A., Hartmann, D., & Hornig, D. (1979) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/32.3.530 · Cited by 222 · see citing works
High-dose antioxidant supplements and cognitive function in community-dwelling elderly women
Grodstein, F., Chen, J., & Willett, W. C. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.4.975 · Cited by 214 · cited 1× · see citing works
“It's not surprising, then, that 10 years help to maintain better cognitive functions in these two nutrients can be effective partners in reducing women in their 70’s (Grodstein et al., 2003). the destructive process of lipid per-oxidation.”
BackgroundCarotenoids, vitamins C and E, and mortality in an elderly population.
Sahyoun, N. R., Jacques, P. F., & Russell, R. M. (1996) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a008957 · Cited by 212 · cited 2× · see citing works
“Since heart disease than do people with a daily intake of 60 oxidative damage is a suspected cause of cataracts, the mg/day or less (Sahyoun, 1996). addition of antioxidants to the diet may help prevent their One study has shown that low serum ascorbic acid occurrence.”
BackgroundWeber, C., Erl, W., Weber, K., & Weber, P. C. (1996) · Circulation · doi:10.1161/01.cir.93.8.1488 · Cited by 195 · cited 3× · see citing works
“Strenuous exercise increases the body's cells to damaged arteries (Rath, 1993; Weber, 1996; production of free radicals, which in turn can cause Lehr, 1995). muscle damage, which manifest as swollen or painful Supplementation with 2 g/day of vitamin C has been muscles.”
BackgroundAntioxidant status in persons with and without senile cataract.
Jacques, P., Chylack, L., Mcgandy, R., & Hartz, S. C. (1988) · A M A Archives of Ophthalmology · doi:10.1001/archopht.1988.01060130363022 · Cited by 193 · cited 1× · see citing works
“If the decrease the likelihood of developing cataracts association between low SAA levels and all-cause (Jacques et al., 1988). mortality is causal, increasing the consumption of Vitamin C reduces elevated pressure in the eye due to ascorbic acid and thereby SAA levels, can decrease the glaucoma…”
BackgroundAsthma, inhaled oxidants, and dietary antioxidants.
Hatch, G. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/61.3.625s · Cited by 192 · see citing works
Antioxidant Micronutrients and Immune Responses
Bendich, A. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb00144.x · Cited by 189 · cited 1× · see citing works
“A Californian study has concluded of electrons therefore it "can donate electrons to free that people who consume more than 750 mg/d of radicals such as hydroxyl and superoxide radicals and vitamin C reduce their risk of dying prematurely by 60% quench their reactivity" (Bendich, 1990).”
BackgroundHalliwell, B., Wasil, M., & Grootveld, M. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)81456-4 · Cited by 189 · cited 1× · see citing works
“Halliwell, 1987).”
Ascorbic acid supplementation in the treatment of pressure-sores.
Taylor, T., Rimmer, S., Day, B., Butcher, J., & Dymock, I. (1974) · The Lancet · doi:10.1016/s0140-6736(74)91874-1 · Cited by 161 · see citing works
Does diabetes mellitus increase the requirement for vitamin C?
Will, J. C., & Byers, T. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1996.tb03932.x · Cited by 156 · cited 3× · see citing works
“It also lowers accumulation of the sugar sorbitol (Will and Tyers, 1996), which can damage acid lowers blood histamine. eyes and kidneys.”
BackgroundHarakeh, S., Jariwalla, R., & Pauling, L. (1990) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.3109/13590849009097890 · Cited by 153 · cited 1×
“A daily intake of 250-1000 mg/d may be adequate for In laboratories, Vitamin C has been found to inhibit preventive purposes, but far larger quantities are HIV replication (Harakeh, 1990).”
BackgroundThe Effects of Ascorbic Acid Supplementation on the Absorption of Iron in Maize, Wheat and Soya
Sayers, M. H., Lynch, S. R., Jacobs, P., Charlton, R. W., Bothwell, T., Walker, R., & Mayet, F. (1973) · British Journal of Haematology · doi:10.1111/j.1365-2141.1973.tb05741.x · Cited by 146
Lunec, J., & Blake, D. (1985) · Free Radical Research Communications · doi:10.3109/10715768509056534 · Cited by 144 · see citing works
Hemilä, H. (1992) · British Journal Of Nutrition · doi:10.1079/bjn19920004 · Cited by 143 · see citing works
Micronutrients and Immune Functions
Chandra, R. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb00128.x · Cited by 136
Ascorbic acid-induced uricosuria. A consequency of megavitamin therapy.
Stein, H., Hasan, A., & Fox, I. (1976) · Annals of Internal Medicine · doi:10.7326/0003-4819-84-4-385 · Cited by 127 · cited 1× · see citing works
“Vitamin C also increases the urinary Vitamin C in doses of approximately 1g daily has shown excretion of uric acid (Stein, 1976).”
BackgroundTaylor, A., Jacques, P. F., Nadler, D. J., Morrow, F. D., Sulsky, S. I., & Shepard, D. (1991) · Current Eye Research · doi:10.3109/02713689109013869 · Cited by 124 · cited 1× · see citing works
“Low SAA antioxidant in the eyes (Taylor et al., 1991).”
Cataract: relationship between nutrition and oxidation.
Taylor, A. (1993) · Journal of the American College of Nutrition · doi:10.1080/07315724.1993.10718294 · Cited by 121 · cited 2× · see citing works
“levels have also been a risk factor for cancer death in of vitamin C appear to decrease with age (Taylor, 1993),”
BackgroundEffect of high dose vitamin C on urinary oxalate levels.
Wandzilak, T., D'Andre, S., Davis, P., & Williams, H. (1994) · Journal of Urology · doi:10.1016/s0022-5347(17)35100-5 · Cited by 118 · see citing works
Relation of Serum Ascorbic Acid to Mortality Among US Adults
Simon, J., Hudes, E., & Tice, J. (2001) · Journal of the American College of Nutrition · doi:10.1080/07315724.2001.10719040 · Cited by 117 · cited 2× · see citing works
“It must be risk of death among Americans with low ascorbic acid taken in large doses - often upto 20 grams daily - and is intakes (Joel et al., 2001).”
BackgroundLehr, H., Frei, B. B., Olofsson, A. M., Carew, T. E., & Arfors, K. ‐. (1995) · Circulation · doi:10.1161/01.cir.91.5.1525 · Cited by 116 · cited 2× · see citing works
“Strenuous exercise increases the body's cells to damaged arteries (Rath, 1993; Weber, 1996; production of free radicals, which in turn can cause Lehr, 1995). muscle damage, which manifest as swollen or painful Supplementation with 2 g/day of vitamin C has been muscles.”
BackgroundSome behavioral effects of ascorbic acid deficiency.
Kinsman, R., & Hood, J. (1971) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/24.4.455 · Cited by 109 · cited 1× · see citing works
“Neurotic disturbances consisting of hypochondriasis, hysteria and depression followed by decreased psychomotor performances have been reported in ascorbic acid deficiency (Kinsman and Hood, 1971).”
BackgroundVitamin C intake and susceptibility to the common cold
Hemilä, H. (1997) · British Journal of Nutrition · doi:10.1017/s0007114500002889 · Cited by 108 · cited 1× · see citing works
“The mechanism for this effect is unclear quantitatively meaningful only in specific groups of hence further confirmatory studies are indicated. subjects and is not very large (Hemila, 1997).”
BackgroundCunningham, J., Ellis, S. L., Mcveigh, K., Levine, R., & Calles-Escandón, J. (1991) · Metabolism: Clinical and Experimental · doi:10.1016/0026-0495(91)90165-s · Cited by 102 · cited 1× · see citing works
“It has helped to alleviate pancreatitis, or an inflammation of the Role of vitamin C in the various body disorders: It has been reported that diabetic individual have low levels of vitamin C in the plasma and in the white blood cells (Cunningham et al., 1991), which constitute our immune defense.”
BackgroundRelationship between ascorbic acid and male fertility.
Dawson, E. B., Harris, W. A., & Powell, L. C. (1990) · World Review of Nutrition and Dietetics · doi:10.1159/000417532 · Cited by 98 · cited 1× · see citing works
“One gram of Vitamin C, Vitamin C prevents free radical damage in the lungs and taken daily, helps to increase fertility in men who have may even help to protect the central nervous system problems with sperm agglutination (Dason et al., 1990). from such damage (Kronhausen et al., 1989a).”
BackgroundAnderson, R., & Lukey, P. T. (1987) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1987.tb23764.x · Cited by 92 · see citing works
Wittes, R. E. (1985) · New England Journal of Medicine · doi:10.1056/nejm198501173120310 · Cited by 85 · see citing works
Influence of ascorbic acid supplementation on copper status in young adult men.
Finley, E. B., & Cerklewski, F. L. (1983) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/37.4.553 · Cited by 77 · cited 1× · see citing works
“High levels of vitamin C interfere with copper absorption (Finley and Cerklewski, 1983).”
BackgroundActive transport of L-ascorbic acid in the human ileum.
Stevenson, N. R. (1974) · Gastroenterology · doi:10.1016/s0016-5085(19)32749-0 · Cited by 73 · cited 1× · see citing works
“While gastrointestinal absorption is through an efficient and an active sodium dependent, energy-requiring and carrier-mediated transport mechanism (Stevenson, 1974).”
BackgroundVitamin C in the treatment of acquired immune deficiency syndrome (AIDS).
Cathcart, R. (1984) · Medical Hypotheses · doi:10.1016/0306-9877(84)90149-x · Cited by 61 · cited 1× · see citing works
“An adequate intake of vitamin C is surely the supplement for HIV patients, as it may help with disease best and most cost effective health insurance available resistance and overall well being (Cathcart, 1984). today.”
BackgroundPotential clinical applications for high-dose nutritional antioxidants.
Crary, E., & McCarty, M. (1984) · Medical Hypotheses · doi:10.1016/0306-9877(84)90132-4 · Cited by 48 · cited 1× · see citing works
“As a constituent of retinopathy (Crary and McCarty, 1984; Sinclair et al., collagen, vitamin C may contribute to immune defense 1992).”
BackgroundVITAMIN C, THE COMMON COLD, AND THE FLU
Barley, S. (1978) · doi:10.2307/4445899 · Cited by 42 · cited 1×
“In 1976, he proposed even higher doses, in his book "Vitamin C, the Common Cold and the Flu" (Pauling, 1976).”
BackgroundPossible prevention of postangioplasty restenosis by ascorbic acid.
Tomoda, H., Yoshitake, M., Morimoto, K., & Aoki, N. (1996) · American Journal of Cardiology · doi:10.1016/s0002-9149(96)00613-3 · Cited by 40 · cited 2× · see citing works
“supplementing with ascorbic acid (500 mg/day) Cataracts are extremely common and happen with most (Tomoda, 1996).”
BackgroundGeber, W., Lefkowitz, S., & Hung, C. (1975) · Pharmacology · doi:10.1159/000136908 · Cited by 36 · see citing works
Vitamin C influence on localized adjuvant arthritis.
Davis, R., Rosenthal, K., Cesario, L., & Rouw, G. (1990) · Journal of the American Podiatric Medical Association (Print) · doi:10.7547/87507315-80-8-414 · Cited by 26
Effect of ascorbic acid on the disease caused by Escherichia coli challenge infection.
Gross, W., Jones, D., & Cherry, J. (1988) · Avian diseases · doi:10.2307/1590904 · Cited by 21
Vitamin Intake and Health: A Scientific Review
Glade, M. (1991) · JAMA · doi:10.1001/jama.1991.03470130139050 · Cited by 19 · see citing works
Sherman, C. (1994) · Physician and sportsmedicine · doi:10.1080/00913847.1994.11710449 · Cited by 19 · cited 1×
“…the blood from rheumatoid arthritis patients are helps thin the blood and protects it against oxidation and extremely low and that vitamin C may protect against works in close synergism with vitamin E (Rath, 1993; further damage to inflamed joints (Lunec, 1985; Whitaker, 1985; Trout et al., 1991).”
BackgroundVitamin C prophylaxis for posttransfusion hepatitis: lack of effect in a controlled trial.
Knodell, R., Tate, M. A., Akl, B. F., & Wilson, J. (1981) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/34.1.20 · Cited by 16 · cited 3×
“On the average, vitamin C produces greater reducing risk of hepatitis infection (Knodell et al., 1981). benefit for children than for adults.”
BackgroundInfluentialDiet, Nutrition, and Cancer Research: An Overview
Jacobs, M. M. (1993) · doi:10.1097/00017285-199305000-00004 · Cited by 12 · cited 1×
“…severity of illnesses (Hemila, 1992). breast, cervix, colon, rectum, esophagus, larynx, lung, Gaby and Singh (1991) reports that in 1981, in one mouth, prostate and stomach (Levine, 1996; Block, study, when 1 g of vitamin C was given intravenously to 1992; Frei, 1994; Block, 1991; Jacobs, 1993).”
BackgroundNicholas, D. (1945) · Nature · doi:10.1038/155433b0 · Cited by 10
Axelrod, D. R. (1985) · JAMA · doi:10.1001/jama.1985.03360100058010 · Cited by 9 · cited 1× · see citing works
“There incidence of urinary tract infection (UTI) (Axelrod, 1985). appears to be a modest benefit in reducing duration of cold symptoms from ingestion of relatively high doses of RDA of vitamin C: Vitamin C is truly a wonder nutrient vitamin C.”
BackgroundRecommendations for antioxidants: how much evidence is enough?
Voelker, R. A. (1994) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.1994.03510390012005 · Cited by 6
Inhibitory effect of high dose ascorbic acid on inflammatory edema
Spillert, C., Spillert, K. R., Hollinshead, M., & Lazaro, E. (1989) · Agents and Actions · doi:10.1007/bf01972834 · Cited by 4 · cited 2×
“Vitamin C also protects us by but not before the injury successfully suppressed preventing the development of nitrosamines, the canceredema (Spillert, 1989). causing chemicals that stem from the nitrates contained As an antioxidant, vitamin C can rejuvenate vitamin E, in many foods (Gaby and Singh,…”
BackgroundRuskin, S. (1947) · The American Journal of Digestive Diseases · doi:10.1007/bf03001346 · Cited by 4 · cited 1×
“Vitamin C supplementation (2 g/d) also 1996). effectively reverses the vasomotor dysfunction often Vitamin C acting as an antioxidant is helpful in the found in patients with atherosclerosis (Levine, 1996). treatment of asthma ( Ruskin, 1947).”
BackgroundWoodhouse, P., & Khaw, K. (1994) · doi:10.1093/ageing/23.suppl_2.p5-a · Cited by 4
Goldin (1977) · doi:10.1002/1097-0142(197711)40:5+
Flagged first, then by citations
25 of the 94 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Bioactive Compounds and Health-Promoting Properties of Berry Fruits: A Review
Szajdek, A., & Borowska, E. (2008) · Plant foods for human nutrition · doi:10.1007/s11130-008-0097-5 · Cited by 643 · see citing works
“It is involved in the process of detoxification of air pollutants, such as ozone, NO2 and free radicals of cigarette smoke [ 112 ].”
BackgroundEpidermal enzymatic biosensors for sweat vitamin C: Toward personalized nutrition
Sempionatto, J. R., Khorshed, A. A., Ahmed, A., De Loyola e Silva, A. N., Barfidokht, A., Yin, L., Goud, K. Y., Mohamed, M. A., Bailey, E., May, J., et al. (2020) · ACS Sensors · doi:10.1021/acssensors.0c00604 · Cited by 256 · see citing works
Shen, J., Griffiths, P. T., Campbell, S. J., Utinger, B., Kalberer, M., & Paulson, S. (2021) · Scientific Reports · doi:10.1038/s41598-021-86477-8 · Cited by 228 · see citing works
Utility of antioxidants during assisted reproductive techniques: an evidence based review
Agarwal, A., Durairajanayagam, D., & du Plessis, S. (2014) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-12-112 · Cited by 227 · see citing works
“It is unstable, easily oxidized and perishable in high temperatures [153].”
Oxidative Stress and Male Infertility: The Protective Role of Antioxidants
Kaltsas, A. (2023) · Medicina · doi:10.3390/medicina59101769 · Cited by 221 · see citing works
The role of wild fruits and vegetables in delivering a balanced and healthy diet.
Bvenura, C., & Sivakumar, D. (2017) · Food Research International · doi:10.1016/j.foodres.2017.06.046 · Cited by 204 · see citing works
Male Infertility: The Effect of Natural Antioxidants and Phytocompounds on Seminal Oxidative Stress
Adewoyin, M., Ibrahim, M., Ramli, R., Isa, M., Alewi, N. A. M., Rafa, A. A. A., & Anuar, M. N. N. (2017) · Diseases · doi:10.3390/diseases5010009 · Cited by 197 · see citing works
“It helps in the metabolic processes of folic acid, tyrosine and tryptophan [68].”
BackgroundA Comprehensive Review on Nutritional Value, Medicinal Uses, and Processing of Banana
Ranjha, M. M. A. N., Irfan, S., Nadeem, M., & Mahmood, S. (2022) · Food Reviews International · doi:10.1080/87559129.2020.1725890 · Cited by 176 · see citing works
“Ascorbic acid also helps in reduction of severe allergic reactions, fighting the infections, and most importantly in the proper regulation and functioning of the immune system.([25])”
BackgroundFetoui, H., Makni, M., Garoui, E., & Zeghal, N. (2010) · Experimental and Toxicological Pathology · doi:10.1016/j.etp.2009.08.004 · Cited by 173 · see citing works
Lithium toxicity in plants: Reasons, mechanisms and remediation possibilities - A review.
Shahzad, B., Tanveer, M., Hassan, W., Shah, A. N., Anjum, S., Cheema, S., & Ali, I. (2016) · Plant physiology and biochemistry : PPB · doi:10.1016/j.plaphy.2016.05.034 · Cited by 168 · see citing works
“It is also known as vitamin C and is involved in the biosynthesis of neurotransmitters and collagen (Iqbal et al., 2004).”
BackgroundMelon (Cucumis melo L.) by-products: Potential food ingredients for novel functional foods?
Silva, M. A., Albuquerque, T. G., Alves, R. C., Oliveira, M. B. P. P., & Costa, H. S. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.07.005 · Cited by 161 · see citing works
Review on nanomaterials-enabled electrochemical sensors for ascorbic acid detection.
Dhara, K., & Debiprosad, R. M. (2019) · Analytical Biochemistry · doi:10.1016/j.ab.2019.113415 · Cited by 138 · see citing works
Determination and identification of organic acids in wine samples. Problems and challenges
Robles, A. D., Fabjanowicz, M., Chmiel, T., & Płotka‐Wasylka, J. (2019) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2019.115630 · Cited by 148 · see citing works
Is lithium biologically an important or toxic element to living organisms? An overview
Shahzad, B., Mughal, M., Tanveer, M., Gupta, D., & Abbas, G. (2016) · Environmental science and pollution research international · doi:10.1007/s11356-016-7898-0 · Cited by 120 · see citing works
Novel curcumin ascorbic acid cocrystal for improved solubility
Pantwalawalkar, J., More, H., Bhange, D., Patil, U., & Jadhav, N. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.102233 · Cited by 85 · see citing works
Latocha, P., Lata, B., & Stasiak, A. (2015) · Journal of Functional Foods · doi:10.1016/j.jff.2015.09.024 · Cited by 82 · see citing works
Ademiluyi, A., Oboh, G., Aragbaiye, F. P., Oyeleye, S. I., & Ogunsuyi, O. (2015) · Journal of Taibah University Medical Sciences · doi:10.1016/j.jtumed.2014.11.005 · Cited by 75 · see citing works
El-Demerdash, F., Yousef, M., & Zoheir, M. (2005) · Food and Chemical Toxicology · doi:10.1016/j.fct.2005.05.017 · Cited by 74
Kalinowska, M., Hawrylak-Nowak, B., & Szymańska, M. (2013) · Biological Trace Element Research · doi:10.1007/s12011-013-9606-y · Cited by 67
“It is commonly known as vitamin C— a water-soluble vitamin important for humans and animals that is involved in the biosynthesis of neurotransmitters, collagen and carnitine [10].”
Güney, G., Kutlu, H. M., & Genç, L. (2014) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/j.colsurfb.2014.05.008 · Cited by 63
El‐Nakhel, C., Pannico, A., Graziani, G., Kyriacou, M. C., Giordano, M., Ritieni, A., Pascale, S. D., & Rouphael, Y. (2020) · Antioxidants · doi:10.3390/antiox9040300 · Cited by 72 · see citing works
“Furthermore, ascorbic acid can revitalize other antioxidant compounds like α-tocopheroxyl and β-carotene radical cations from their radical species [36], and can rejuvenate vitamin E [37].”
BackgroundHepatoprotective Influence of Vitamin C on Thioacetamide-induced Liver Cirrhosis in Wistar Male Rats
Al-Attar, A. M. (2011) · Journal of Pharmacology and Toxicology · doi:10.3923/jpt.2011.218.233 · Cited by 50 · see citing works
Bioactive Compounds and Aroma Profile of Some Lamiaceae Edible Flowers
Marchioni, I., Najar, B., Ruffoni, B., Copetta, A., Pistelli, L., & Pistelli, L. (2020) · Plants · doi:10.3390/plants9060691 · Cited by 84 · see citing works
“This molecule plays a relevant role in the development and maintenance of connective tissues, in bone formation and wound healing [65].”
BackgroundRaji, Y. R., Oyeyemi, W., Shittu, S., & Bolarinwa, A. (2011) · doi:10.4314/njps.v26i1 · Cited by 60
Godlewska, K., Pacyga, P., Najda, A., & Michalak, I. (2023) · Molecules · doi:10.3390/molecules28145572 · Cited by 72 · see citing works
“In view of the fact that this vitamin is not synthesized by the human body, it has to be provided with diet [62].”
BackgroundNanostructured Metal Oxide-Based Electrochemical Biosensors in Medical Diagnosis
Keles, G., Ataman, E. S., Taskin, S. B., Polatoğlu, I., & Kurbanoğlu, S. (2024) · Biosensors · doi:10.3390/bios14050238 · Cited by 58 · see citing works
Bioactive components of onion (Allium cepa L.) — a Review
Bystrická, J., Musilová, J., Vollmannová, A., Timoracká, M., & Kavalcová, P. (2013) · doi:10.1556/aalim.42.2013.1.2 · Cited by 57
The Role of Vitamins in Autism Spectrum Disorder: What Do We Know?
Bjørklund, G., Waly, M. I., Al-Farsi, Y. M., Saad, K., Dadar, M., Rahman, M. M., Elhoufey, A. A., Chirumbolo, S., Jóźwik-Pruska, J., & Kałużna‐Czaplińska, J. (2019) · Journal of Molecular Neuroscience · doi:10.1007/s12031-018-1237-5 · Cited by 70 · see citing works
Ambali, S., Idris, S., Onukak, C., Shittu, M., & Ayo, J. (2010) · Toxicology and industrial health · doi:10.1177/0748233710373086 · Cited by 54 · see citing works
“Besides, vitamin C plays an essential role in the formation of norepinephrine from dopamine (Iqbal et al., 2004), which eventually increases the availability of norepinephrine essential in the successful performance of beam walk task.”
BackgroundAntioxidant Role of Ascorbic Acid and His Protective Effects on Chronic Diseases
Barrita, J. L. S., & Sánchez, M. D. S. S. (2013) · InTech eBooks · doi:10.5772/52181 · Cited by 53 · see citing works
Fabrication of Coaxial Wet‐Spun Graphene–Chitosan Biofibers
Mirabedini, A., Foroughi, J., Thompson, B., & Wallace, G. (2016) · Advanced Engineering Materials · doi:10.1002/adem.201500201 · Cited by 50 · see citing works
Zhang, J., Gao, N., Shu, C., Cheng, S., Sun, X., Chang-jiang, L., Xin, G., Li, B., & Tian, J. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.689038 · Cited by 48 · see citing works
From in planta Function to Vitamin-Rich Food Crops: The ACE of Biofortification
Strobbe, S., Lepeleire, J. D., & Straeten, D. V. D. (2018) · Frontiers in Plant Science · doi:10.3389/fpls.2018.01862 · Cited by 53 · see citing works
“In addition, ascorbate is known to ameliorate iron uptake in humans (Iqbal et al., 2004).”
BackgroundInfluentialHemotoxicity Induced by Chronic Chlorpyrifos Exposure in Wistar Rats: Mitigating Effect of Vitamin C
Ambali, S., Ayo, J., Esievo, K., & Ojo, S. (2011) · Veterinary Medicine International · doi:10.4061/2011/945439 · Cited by 47
Al-Rejaie, S., Abuohashish, H., Alkhamees, O., Aleisa, A., & AlRoujayee, A. (2012) · Lipids in Health and Disease · doi:10.1186/1476-511x-11-41 · Cited by 46
Matteo, A. D., Simeone, G. D. R., Cirillo, A., Rao, M. A., & Vaio, C. D. (2020) · Scientia Horticulturae · doi:10.1016/j.scienta.2020.109741 · Cited by 52 · see citing works
Biochemistry of Fat Soluble Vitamins, Sources, Biochemical Functions and Toxicity
Rafeeq, H., Ahmad, S., Tareen, M. B. K., Shahzad, K. A., Bashir, A., Jabeen, R., Tariq, S., & Shehzadi, I. (2020) · Haya The Saudi Journal of Life Sciences · doi:10.36348/sjls.2020.v05i09.007 · Cited by 51 · see citing works
“For the modulation of certain bloodcoagulation proteins or the control of calcium binding in bones and other tissues, the human body requires vitamin K [6].”
BackgroundProbiotic Viability, Physicochemical and Sensory Properties of Probiotic Pineapple Juice
Adebayo-Tayo, B., & Akpeji, S. (2016) · Fermentation · doi:10.3390/fermentation2040020 · Cited by 45 · see citing works
TFOS Lifestyle: Impact of nutrition on the ocular surface
Markoulli, M. P., Ahmad, S., Arcot, J., Arita, R., Benitez-del-Castillo, J., Caffery, B. E., Downie, L. E., Edwards, K. P., Flanagan, J., Labétoulle, M., et al. (2023) · The Ocular Surface · doi:10.1016/j.jtos.2023.04.003 · Cited by 53 · see citing works
Narayanan, S. N., Kumar, R. S., Paval, J., & Nayak, S. (2010) · Bratislava Medical Journal · doi:10.1007/bf03657363 · Cited by 43 · see citing works
Antidiabetic and Antioxidant Activity of Jackfruit ( Artocarpus Heterophyllus ) Extract
Biworo, A., Tanjung, E., & Suhartono, E. (2014) · doi:10.12720/jomb.4.4.318-323 · Cited by 42
“It is an unstable, easily oxidized acid and can be destroyed by oxygen, alkali and high temperature [34].”
BackgroundPlasma Vitamin C Concentrations and Cognitive Function: A Cross-Sectional Study
Travica, N., Ried, K., Sali, A., Hudson, I. L., Scholey, A. B., & Pipingas, A. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00072 · Cited by 48 · see citing works
Mamede, A. C., Pires, A. S., Abrantes, A. M., Tavares, S. D., Gonçalves, A. C., Casalta‐Lopes, J., Sarmento‐Ribeiro, A. B., Maia, J. M., & Botelho, M. F. (2012) · Nutrition and Cancer · doi:10.1080/01635581.2012.713539 · Cited by 38 · see citing works
“Of the 3 possible routes, the intravenous was ideal due to much higher plasma concentrations of vitamin C obtained (6,32).”
BackgroundSusa, F., & Pisano, R. (2023) · Processes · doi:10.3390/pr11113167 · Cited by 41 · see citing works
Joy, M., & Chakraborty, K. (2017) · doi:10.1080/10498850.2015.1092486 · Cited by 37
“It, furthermore, helps the body assimilate to iron and calcium, assists in wound recovery, and helps cerebrum capacity (Iqbal et al., 2004).”
BackgroundChauhan, N., Dahiya, T., & Pundir, C. (2010) · doi:10.1016/j.molcatb.2010.07.007 · Cited by 37
Vega‐Gálvez, A., Rodríguez, A., & Stucken, K. (2020) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.10621 · Cited by 44 · see citing works
L-Ascorbic acid (vitamin C) supplementation to optimize health and reproduction in cattle
Ranjan, R., Ranjan, A., Dhaliwal, G. S., & Patra, R. (2012) · Veterinary Quarterly · doi:10.1080/01652176.2012.734640 · Cited by 36
“Vitamin C circulates freely in plasma, leukocytes, and red blood cells and enters into all tissues and body fluids in human beings (Iqbal et al. 2004).”
BackgroundAntioxidant potential of Moringa leaves for improvement of milk and serum quality of Aardi goats
Al-Juhaimi, F., Alsawmahi, O. N., Abdoun, K., Ghafoor, K., & Babiker, E. E. (2020) · doi:10.1016/j.sajb.2019.03.022 · Cited by 35
“The experimental diets showed significant effects on both milk and serum vitamin C content, especially in goats fed with MOD, where vitamin C can be absorbed and circulates freely in plasma to enter into all tissues and body fluids (Iqbal et al., 2004).”
BackgroundAntibacterial effect of pineapple (Ananas comosus) extract towards Staphylococcus aureus
Yong, K.-L.-O., Satari, M., & Dewi, W. (2018) · Padjadjaran Journal of Dentistry · doi:10.24198/pjd.vol30no1.16099 · Cited by 34 · see citing works
Repositioning Vitamin C as a Promising Option to Alleviate Complications associated with COVID-19
Farjana, M., Moni, A., Sohag, A. A. M., Hasan, A., Hannan, M. A., Hossain, M. G., & Uddin, M. J. (2020) · Infection and Chemotherapy · doi:10.3947/ic.2020.52.4.461 · Cited by 35 · see citing works
“Beyond these, vitamin C was found to be effective against a range of COVID-19 comorbidities, including diabetes [9], hypertension [10], cardiovascular diseases [11], kidney infections [12], cancer [13], and microbial infections [14].”
BackgroundRobles, A., Fabjanowicz, M., Płotka-Wasylka, J., & Konieczka, P. (2019) · Molecules · doi:10.3390/molecules24234376 · Cited by 33
“Moreover, there is a lack of knowledge regarding the beneficial effects of the consumption of foods rich in these compounds, with the exception of ascorbic acid, which has a high antioxidant power [4].”
BackgroundJayathunge, K. G. L. R., Stratakos, A., Delgado-Pando, G., & Koidis, A. (2019) · Journal of food processing and preservation · doi:10.1111/jfpp.13901 · Cited by 33
Mani, D., Sharma, B., Kumar, C., & Balak, S. (2012) · Proceedings of the National Academy of Sciences India Section B Biological Sciences · doi:10.1007/s40011-012-0057-6 · Cited by 37 · see citing works
Xu, D.-P., Qi, S., Chen, Y., Yin, M., Zhang, L., Ge, K., Wei, X.-X., Tian, X., Wang, P., Li, M., et al. (2021) · Chemical Physics Letters · doi:10.1016/j.cplett.2021.138749 · Cited by 32 · see citing works
Lu, M., Li, B., Guan, L., Li, K., & Lin, Y.-Q. (2019) · ACS Sustainable Chemistry and Engineering · doi:10.1021/acssuschemeng.9b03095 · Cited by 32
Tidak ada perbedaan respon imun perokok berat dan perokok ringan karena asupan mikronutrien
Sugeng, M. W., Adriani, M., & Wirjatmadi, B. (2014) · Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) · doi:10.14710/jgi.2.1 · Cited by 31 · see citing works
Princwill-Ogbonna, I., Ogbonna, P., & Ogujiofor, I. (2019) · Journal of Applied Sciences and Environmental Management · doi:10.4314/jasem.v23i1.11 · Cited by 30 · see citing works
“Ascorbic acid (vitamin C) as an antioxidant helps to prevent cell damage caused by free radicals in the body, thus, reducing the rate of aging and development of heart disease, cancer and arthritis as well as optimizes the body’s immune function and enhances wound healing (Iqbal et al., 2004).”
BackgroundMohajer, S., Taha, R. M., Ramli, R., & Mohajer, M. (2016) · Industrial Crops and Products · doi:10.1016/j.indcrop.2016.09.045 · Cited by 36 · see citing works
Stanescu, C. M., Chiscop, I., Mihalache, D., Boev, M., Tamaş, C., & Stoleriu, G. (2025) · Molecules · doi:10.3390/molecules30173568 · Cited by 37 · see citing works
“It promotes wound healing by favorably influencing the inflammatory, proliferative, and remodeling phases, as well as boosting extracellular matrix formation, which is essential for tissue regeneration [16].”
Spectroscopic properties of Vitamin C: A theoretical work
Ahmed, L., & Omer, R. (2020) · Cumhuriyet Science Journal · doi:10.17776/csj.762184 · Cited by 29 · see citing works
PHYTO-NUTRITIONAL PROFILES OF BROOM WEED (SIDA ACUTA) LEAF EXTRACT
Shittu, M., & Alagbe, J. (2020) · International Journal on Integrated Education · doi:10.31149/ijie.v3i11.845 · Cited by 29
“[29] vitamin C is essential for the development and maintenance of connective tissues.”
BackgroundBaschieri, A., Amorati, R., Benelli, T., Mazzocchetti, L., d’Angelo, E., & Valgimigli, L. (2019) · Antioxidants · doi:10.3390/antiox8020030 · Cited by 29
“Ascorbic acid is essential to the biosynthesis of collagen and other biomolecules, and it also protects from several chronic diseases including neurodegenerative conditions, heart disease, eye disease, and can serve as an adjuvant in the treatment of cancer [8,9].”
BackgroundLeón, E., Iwasaki, K., Komaki, M., Kojima, T., & Ishikawa, I. (2007) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2007.00977.x · Cited by 28 · see citing works
Vitamin C fortification: need and recent trends in encapsulation technologies
Maurya, V. K., Shakya, A., McClements, D. J., Srinivasan, R., Bashir, K., Ramesh, T., Lee, J., & Sathiyamoorthi, E. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1229243 · Cited by 35 · see citing works
Cendrowski, A., Studnicki, M., & Kalisz, S. (2024) · Applied Sciences · doi:10.3390/app14020691 · Cited by 26 · see citing works
“In general, Vitamin C is a natural antioxidant that primarily exists in and is available in its reduced form as L-ascorbic acid and its oxidized form as L-dehydroascorbic acid [55].”
BackgroundWang, L.-B., Ma, M., Zhang, S., Wu, Z., Li, J., Luo, W., Guo, L., Lin, W., & Zhang, S.-L. (2021) · Scientia Horticulturae · doi:10.1016/j.scienta.2021.110178 · Cited by 26
Kwiecińska-Piróg, J., Skowron, K., Bogiel, T., Białucha, A., Przekwas, J., & Gospodarek-Komkowska, E. (2019) · Antibiotics · doi:10.3390/antibiotics8030116 · Cited by 26
Health-promoting properties of Corchorus leaves: A review
Kumari, N., Choudhary, S. B., Sharma, H. K., Singh, B. K., & Kumar, A. A. (2018) · Journal of Herbal Medicine · doi:10.1016/j.hermed.2018.10.005 · Cited by 30 · see citing works
Musa, A., & Ogbadoyi, E. (2012) · doi:10.3923/ajb.2012.63.79 · Cited by 26
Beigoli, S., Behrouz, S., Memarzia, A., Ghasemi, S. Z., Boskabady, M., Marefati, N., Kianian, F., Khazdair, M., El-Seedi, H. R., & Boskabady, M. (2021) · Evidence-Based Complementary and Alternative Medicine · doi:10.1155/2021/5554259 · Cited by 25 · see citing works
“(is water-soluble vitamin is reversible for the entire redox system [43, 44].”
BackgroundGraphene and Natural Products: A Review of Antioxidant Properties in Graphene Oxide Reduction
dos Santos, F. K. F., Pereira, A. A. M., Nunes, A. L., Fonseca, C. J. N., Isidorio, D., Araújo, F. D. A., Oliveira, P. H. A., & da Veiga, V. D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105182 · Cited by 24
“It can also present another activity, in which the molecule donates electrons to radicals and which will stabilize through resonance, preventing such radicals from reacting with oxygen or other molecules to form more reactive radicals [50].”
BackgroundAryal, K., & Jeong, H. (2019) · Chemical Physics Letters · doi:10.1016/j.cplett.2019.06.032 · Cited by 24
Evaluation of in vitro Antioxidant Activities of Lemon Juice for Safety Assessment
Hajimahmoo, M., Aliabadipo, M., Moghaddam, G., Sadeghi, N., Oveisi, M., & Jannat, B. (2012) · doi:10.3923/ajft.2012.708.714 · Cited by 24
Sun, P., Li, D.-F., Dong, B., Qiao, S., Ma, X., & Chen, X. (2009) · doi:10.1016/j.foodchem.2008.08.018 · Cited by 24
Aryal, K. P., & Jeong, H. K. (2020) · Chemical Physics Letters · doi:10.1016/j.cplett.2020.137881 · Cited by 23
Yield and fruit quality of sweet pepper depending on foliar application of calcium
Buczkowska, H., Michałojć, Z., & Nurzyńska-Wierdak, R. (2016) · doi:10.3906/tar-1501-56 · Cited by 23
“L-ascorbic acid is one of the most important nutrients of pepper due to its wide biological activity in the human body (Iqbal et al., 2004; Hacişevki, 2009).”
BackgroundIkram, M., Mizuno, R., Putri, S., & Fukusaki, E. (2021) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2021.08.008 · Cited by 22
Zhang, J., Tian, J.-L., Gao, N.-X., Gong, E.-S., Xin, G., Liu, C.-J., Si, X., Sun, X.-Y., & Li, B. (2021) · Food Science & Nutrition · doi:10.1002/fsn3.2525 · Cited by 22
“In this study, the vitamin C content of kiwi berries ranged from 54.32 to 93.94 mg/100 g FW, which was higher than that of orange (51 mg/100 g FW), strawberry (29– 48 mg/100 g FW) (Iqbal et al., 2004), and traditional kiwifruit (Ewa BaranowskaWójcik, 2019).”
BackgroundInfluentialAryal, K. P., & Jeong, H. K. (2021) · Chemical Physics Letters · doi:10.1016/j.cplett.2021.138405 · Cited by 29 · see citing works
Musa, A., & Ogbadoyi, E. (2012) · doi:10.4172/2155-9600.1000140 · Cited by 22
Gubanska, I., Kucińska‐Lipka, J., & Janik, H. (2019) · Polymer Degradation and Stability · doi:10.1016/j.polymdegradstab.2019.02.025 · Cited by 21 · see citing works
Addy, P. S., Bhattacharya, A., Mandal, S. M., & Basak, A. (2014) · RSC Advances · doi:10.1039/c4ra07499h · Cited by 29 · see citing works
Loguercio, L. F., Thesing, A., Noremberg, B. S., Lopes, B. V., Maron, G. K., Machado, G., Pope, M. A., & Carreño, N. L. V. (2022) · ChemElectroChem · doi:10.1002/celc.202200334 · Cited by 19 · see citing works
Banavath, R., Srivastava, R., & Bhargava, P. (2022) · Electrochimica Acta · doi:10.1016/j.electacta.2022.140335 · Cited by 20 · see citing works
Milošević, M., Paunović, M. G., Matić, M., Ognjanović, B., & Saicic, Z. (2017) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2017.09.016 · Cited by 20
Ismail, T. A., Soliman, M. M., NASSAN, M. A., & Mohamed, D. I. (2015) · Journal of Food and Nutrition Research · doi:10.12691/jfnr-3-2-1 · Cited by 20 · see citing works
Patil, R., Gholave, A., Jadhav, J., Yadav, S., & Bapat, V. (2014) · Genetic Resources and Crop Evolution · doi:10.1007/s10722-014-0164-8 · Cited by 20
“Vitamin C has many health effective functions by preventing disorders like diabetes, cataracts, stroke heart diseases, cancer etc. (Iqbal et al. 2004).”
BackgroundAl-Shmgani, H. S., Moate, R. M., MACNAUGHTON, P. D., Sneyd, J. R., & Moody, A. J. (2013) · FEBS Journal · doi:10.1111/febs.12413 · Cited by 17 · see citing works
Micronutrients and Breast Cancer Progression: A Systematic Review
Cuenca-Micó, O., & Aceves, C. (2020) · Nutrients · doi:10.3390/nu12123613 · Cited by 20 · see citing works
Could vitamin C and zinc chloride protect the germ cells against sodium arsenite?
Altoé, L., Reis, I., Gomes, M., Dolder, H., & Pirovani, J. C. M. (2016) · Human & Experimental Toxicology · doi:10.1177/0960327116679714 · Cited by 16 · see citing works
Kolaviron and L-Ascorbic Acid Attenuate Chlorambucil-Induced Testicular Oxidative Stress in Rats
Olayinka, E. T., & Ore, A. (2014) · Journal of Toxicology · doi:10.1155/2014/587015 · Cited by 18
Fruit crops improvement using CRISPR/Cas9 system
Kaur, N., Awasthi, P., & Tiwari, S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818140-9.00012-x · Cited by 22 · see citing works
Hfaiedh, N., Murat, J., & Elfeki, A. (2012) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2012.04.002 · Cited by 17
A study on the effect of natural products against the transmission of B.1.1.529 Omicron
Alkafaas, S. S., Abdallah, A. M., Hussien, A. M., Bedair, H., Abdo, M., Ghosh, S. B., Elkafas, S. S., Apollon, W., Saki, M., Loutfy, S. A., et al. (2023) · Virology Journal · doi:10.1186/s12985-023-02160-6 · Cited by 20 · see citing works
Gil, K., Nowicka, P., Wojdyło, A., Serreli, G., Deiana, M., & Tuberoso, C. (2023) · Antioxidants · doi:10.3390/antiox12040805 · Cited by 16
“[69], ascorbic acid is an antioxidant that protects humans from oxidative stress damage.”
BackgroundEgbuniwe, I. C., Ayo, J., Kawu, M., & Mohammed, A. (2018) · Journal of Applied Animal Welfare Science · doi:10.1080/10888705.2018.1426000 · Cited by 16
Modulation of mutagen-induced genotoxicity by vitamin C and medicinal plants in Allium cepa L.
Asita, A. O., Moramang, S., Rants’o, T., & Magama, S. (2017) · Caryologia · doi:10.1080/00087114.2017.1311166 · Cited by 16 · see citing works
“Vitamin C (ascorbic acid; AA) is a water soluble antioxidant which is found in variable quantities in fruits, vegetables and medicinal plants (Szeto et al. 2002; Iqbal et al. 2004; Ogunlesi et al. 2010).”
BackgroundNatural Bioactive Compounds from Fruits and Vegetables as Health Promoters: Part 2
Silva, L. R. D. D., Silva, B., Nunes, A. R., Mg, A., Oliveira, P., Silva, L. R., Silva, B., Duarte, A., Carvalho, C., Miguel, G., et al. (2016) · doi:10.2174/97816810823941160101 · Cited by 16
Teepoo, S., Chumsaeng, P., Jongjinako, S., Chantu, K., & Nolykad, W. (2012) · doi:10.3923/jas.2012.568.574 · Cited by 16
- Authors
- Iqbal, K., Khan, A., & Khan Khattak, M. M. A.
- Venue
- Pakistan Journal of Nutrition
- Publisher
- Science Insights
- Published
- 2003-12-15
- Volume
- 3
- Issue
- 1
- Pages
- 5-13
- ISSN
- 1680-5194 (ISSN-L)
- 1994-7984
- OpenAlex
- W2111933236
- Cited by
- 270
- References
- 94
- Citations by year
- 2026: 5 · 2025: 11 · 2024: 23 · 2023: 20 · 2022: 18 · 2021: 23 · 2020: 21 · 2019: 25 · 2018: 15 · 2017: 7 · 2016: 20 · 2015: 19 · 2014: 21 · 2013: 9 · 2012: 13
- FWCI
- 0.29
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Pakistan Journal of Nutrition (publishedVersion, cc-by)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Keywords
- vitamin C, scurvy, connective tissue, bone formation, wound healing, gingival health, folic acid, bile acid synthesis, antioxidants, free radicals, immune system, allergy, infection
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
