DNA methylation in metabolic disorders

Epigenetic programming by maternal behavior

Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177

Global and societal implications of the diabetes epidemic

Zimmet, P., Alberti, K. G. M. M., & Shaw, J. (2001) · Nature · doi:10.1038/414782a · Cited by 5,883

Human DNA methylomes at base resolution show widespread epigenomic differences

Lister, R., Pelizzola, M., Dowen, R. H., Hawkins, R. D., Hon, G., Tonti-Filippini, J., Nery, J. R., Lee, L., Ye, Z., Ngo, Q.-M., et al. (2009) · Nature · doi:10.1038/nature08514 · Cited by 4,673

Epigenetic differences arise during the lifetime of monozygotic twins

Fraga, M. F., Ballestar, E., Paz, M. F., Ropero, S., Setien, F., Ballestar, M. L., Heine-Suñer, D., Cigudosa, J. C., Urioste, M., Benitez, J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500398102 · Cited by 3,602

Perceptions of epigenetics

Bird, A. (2007) · Nature · doi:10.1038/nature05913 · Cited by 3,011

Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility

Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005) · Science · doi:10.1126/science.1108190 · Cited by 2,563

Epigenetic inheritance at the agouti locus in the mouse

Morgan, H. D., Sutherland, H. G. E., Martin, D. I. K., & Whitelaw, E. (1999) · Nature Genetics · doi:10.1038/15490 · Cited by 1,476

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

Ng, S.-F., Lin, R. C. Y., Laybutt, D. R., Barres, R., Owens, J. A., & Morris, M. J. (2010) · Nature · doi:10.1038/nature09491 · Cited by 1,327

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a

Ramsahoye, B. H., Biniszkiewicz, D., Lyko, F., Clark, V. H., Bird, A. P., & Jaenisch, R. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.10.5237 · Cited by 1,012

Cyclical DNA methylation of a transcriptionally active promoter

Métivier, R., Gallais, R., Tiffoche, C., Péron, C. L., Jurkowska, R., Carmouche, R. P., Ibberson, D., Baráth, P., Demay, F., Reid, G., et al. (2008) · Nature · doi:10.1038/nature06544 · Cited by 942

Genome-wide methylation profiles reveal quantitative views of human aging rates

Hannum, G., Guinney, J., Zhao, L., Zhang, L., Hughes, G., Sadda, S., Klotzle, B., Bibikova, M., Fan, J.-B., Gao, Y., et al. (2013) · Molecular Cell · doi:10.1016/j.molcel.2012.10.016 · Cited by 4,270

Impact of obesity on male fertility, sperm function and molecular composition

Palmer, N. O., Bakos, H. W., Fullston, T., & Lane, M. (2012) · Spermatogenesis · doi:10.4161/spmg.21362 · Cited by 403

The Circadian Syndrome: is the Metabolic Syndrome and much more!

Zimmet, P., Alberti, K. G. M. M., Stern, N., Bilu, C., El‐Osta, A., Einat, H., & Kronfeld‐Schor, N. (2019) · Journal of Internal Medicine · doi:10.1111/joim.12924 · Cited by 387

Paternal obesity is associated with IGF2hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort

Soubry, A., Schildkraut, J. M., Murtha, A. P., Wang, F. M., Huang, Z., Bernal, A. J., Kurtzberg, J., Jirtle, R. L., Murphy, S. K., & Hoyo, C. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-29 · Cited by 364

The Osteological Paradox 20 Years Later: Past Perspectives, Future Directions

DeWitte, S. N., & Stojanowski, C. M. (2015) · Journal of Archaeological Research · doi:10.1007/s10814-015-9084-1 · Cited by 348

Epigenomics, gestational programming and risk of metabolic syndrome

Desai, M., Jellyman, J. K., & Ross, M. G. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.13 · Cited by 289

Molecular genetics of human obesity: A comprehensive review

Singh, R. K., Kumar, P., & Mahalingam, K. (2017) · Comptes Rendus Biologies · doi:10.1016/j.crvi.2016.11.007 · Cited by 272

Dietary and Gut Microbiota Polyamines in Obesity- and Age-Related Diseases

Ramos-Molina, B., Queipo-Ortuño, M. I., Lambertos, A., Tinahones, F. J., & Peñafiel, R. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00024 · Cited by 226

Physical activity in the prevention of human diseases: role of epigenetic modifications

Grazioli, E., Dimauro, I., Mercatelli, N., Wang, G., Pitsiladis, Y. P., Luigi, L. D., & Caporossi, D. (2017) · BMC Genomics · doi:10.1186/s12864-017-4193-5 · Cited by 197

Minireview: Epigenetic Programming of Diabetes and Obesity: Animal Models

Seki, Y., Williams, L., Vuguin, P. M., & Charron, M. J. (2012) · Endocrinology · doi:10.1210/en.2011-1805 · Cited by 179

Considering Maternal Dietary Modulators for Epigenetic Regulation and Programming of the Fetal Epigenome

Chango, A., & Pogribny, I. (2015) · Nutrients · doi:10.3390/nu7042748 · Cited by 144

Deleterious effects of obesity upon the hormonal and molecular mechanisms controlling spermatogenesis and male fertility

Davidson, L. M., Millar, K., Jones, C., Fatum, M., & Coward, K. (2015) · Human Fertility · doi:10.3109/14647273.2015.1070438 · Cited by 138

Epigenetic regulation on gene expression induced by physical exercise.

Ntanasis‐Stathopoulos, I., Tzanninis, J. G., Philippou, Α., & Koutsilieris, M. (2013) · PubMed · Cited by 134

Epigenetic control of gene regulation during development and disease: A view from the retina

Corso‐Díaz, X., Jaeger, C., Chaitankar, V., & Swaroop, A. (2018) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2018.03.002 · Cited by 130

Epigenetic programming of obesity and diabetes by in utero exposure to gestational diabetes mellitus

Ruchat, S.-M., Hivert, M., & Bouchard, L. (2013) · Nutrition Reviews · doi:10.1111/nure.12057 · Cited by 135

Dietary Intervention Modifies DNA Methylation Age Assessed by the Epigenetic Clock

Sae‐Lee, C., Corsi, S., Barrow, T. M., Kuhnle, G. G. C., Bollati, V., Mathers, J. C., & Byun, H. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201800092 · Cited by 121

Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

Klughammer, J., Romanovskaia, D., Nemc, A., Posautz, A., Seid, C. A., Schuster, L. C., Keinath, M. C., Ramos, J. S. L., Kosack, L., Evankow, A. M., et al. (2023) · Nature Communications · doi:10.1038/s41467-022-34828-y · Cited by 131

Impact of Consuming Extra-Virgin Olive Oil or Nuts within a Mediterranean Diet on DNA Methylation in Peripheral White Blood Cells within the PREDIMED-Navarra Randomized Controlled Trial: A Role for Dietary Lipids

Arpón, A., Milagro, F. I., Razquín, C., Corella, D., Estruch, R., Fitó, M., Martí, A., Martínez‐González, M. Á., Ros, E., Salas‐Salvadó, J., et al. (2017) · Nutrients · doi:10.3390/nu10010015 · Cited by 122

The effect of exercise on skeletal muscle glucose uptake in type 2 diabetes: An epigenetic perspective

dos Santos, J. M., Moreli, M. L., Tewari, S., & Benite‐Ribeiro, S. A. (2015) · Metabolism · doi:10.1016/j.metabol.2015.09.013 · Cited by 108

Exercise and the Regulation of Adipose Tissue Metabolism

Tsiloulis, T., & Watt, M. J. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.06.016 · Cited by 103

Dissecting the Interplay Mechanism between Epigenetics and Gut Microbiota: Health Maintenance and Disease Prevention

Wu, Y., Wang, C., Wan, J., Yao, H., & Yuan, C. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22136933 · Cited by 88

Exercise training alters the genomic response to acute exercise in human adipose tissue

Fabre, O., Ingerslev, L., Garde, C., Donkin, I., Simar, D., & Barrès, R. (2018) · Epigenomics · doi:10.2217/epi-2018-0039 · Cited by 71

Effects of obesity and diabetes on the epigenetic modification of mammalian gametes

Ou, X., Zhu, C., & Sun, S. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27847 · Cited by 78

Metabolic syndrome components are associated with DNA hypomethylation

Luttmer, R., Spijkerman, A. M. W., Kok, R. M., Jakobs, C., Blom, H. J., Serné, E. H., Dekker, J. M., & Smulders, Y. M. (2012) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2012.06.001 · Cited by 76

Obese father’s metabolic state, adiposity, and reproductive capacity indicate son’s reproductive health

McPherson, N. O., Fullston, T., Bakos, H. W., Setchell, B. P., & Lane, M. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.12.007 · Cited by 74

MicroRNAs-Dependent Regulation of PPARs in Metabolic Diseases and Cancers

Portius, D., Sobolewski, C., & Foti, M. (2017) · PPAR Research · doi:10.1155/2017/7058424 · Cited by 72

Short-Term Intensified Cycle Training Alters Acute and Chronic Responses of PGC1α and Cytochrome C Oxidase IV to Exercise in Human Skeletal Muscle

Stepto, N. K., Benziane, B., Wadley, G. D., Chibalin, A., Canny, B. J., Eynon, N., & McConell, G. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0053080 · Cited by 72

Dietary Modifications, Weight Loss, and Changes in Metabolic Markers Affect Global DNA Methylation in Hispanic, African American, and Afro-Caribbean Breast Cancer Survivors,

Delgado‐Cruzata, L., Zhang, W., McDonald, J. A., Tsai, W. Y., Valdovinos, C., Falci, L., Wang, Q., Crew, K. D., Santella, R. M., Hershman, D. L., et al. (2015) · Journal of Nutrition · doi:10.3945/jn.114.202853 · Cited by 69

The effect of fucoxanthin rich power on the lipid metabolism in rats with a high fat diet

Ha, A. W., & Kim, W. K. (2013) · Nutrition Research and Practice · doi:10.4162/nrp.2013.7.4.287 · Cited by 65

Cellular and Molecular Pathophysiology of Gestational Diabetes

Torres‐Torres, J., Monroy-Muñoz, I. E., Duran, J. P., Solis‐Paredes, J. M., Camacho‐Martinez, Z. A., Baca, D., y Sosa, S. E., Martinez-Portilla, R. J., Rojas‐Zepeda, L., Borboa-Olivares, H. J., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252111641 · Cited by 77

Epigenetics and Cellular Metabolism

Xu, W., Wang, F., Yu, Z., & Xin, F. (2016) · Genetics & Epigenetics · doi:10.4137/geg.s32160 · Cited by 69

Gene–Lifestyle Interactions in Obesity

van Vliet‐Ostaptchouk, J. V., Snieder, H., & Lagou, V. (2012) · Current Nutrition Reports · doi:10.1007/s13668-012-0022-2 · Cited by 64

Amino Acids and the Early Mammalian Embryo: Origin, Fate, Function and Life-Long Legacy

Leese, H. J., McKeegan, P. J., & Sturmey, R. G. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18189874 · Cited by 60

DNA methylation provides insight into intergenerational risk for preterm birth in African Americans

Parets, S. E., Conneely, K. N., Kilaru, V., Menon, R., & Smith, A. K. (2015) · Epigenetics · doi:10.1080/15592294.2015.1062964 · Cited by 57

Guidelines for pre-analytical conditions for assessing the methylation of circulating cell-free DNA

Kerachian, M. A., Azghandi, M., Mozaffari‐Jovin, S., & Thierry, A. R. (2021) · Clinical Epigenetics · doi:10.1186/s13148-021-01182-7 · Cited by 61

Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis

Keller, M., Kralisch, S., Rohde, K., Schleinitz, D., Dietrich, A., Schön, M., Gärtner, D., Lohmann, T., Dressler, M., Tönjes, A., et al. (2014) · Diabetologia · doi:10.1007/s00125-014-3356-z · Cited by 46

Gene Expression and DNA Methylation of PPARGC1A in Muscle and Adipose Tissue From Adult Offspring of Women With Diabetes in Pregnancy

Kelstrup, L., Hjort, L., Houshmand‐Oeregaard, A. S., Clausen, T. D., Hansen, N. S., Broholm, C., Borch‐Johnsen, L., Mathiesen, E. R., Vaag, A. A., & Damm, P. (2016) · Diabetes · doi:10.2337/db16-0227 · Cited by 57

DNA methylation landscapes in the pathogenesis of type 2 diabetes mellitus

Zhou, Z. G., Sun, B., Li, X., & Zhu, C. (2018) · Nutrition & Metabolism · doi:10.1186/s12986-018-0283-x · Cited by 56

DNA Methylation and Type 2 Diabetes: Novel Biomarkers for Risk Assessment?

Raciti, G. A., Desiderio, A., Longo, M., Leone, A., Zatterale, F., Prevenzano, I., Miele, C., Napoli, R., & Bèguinot, F. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111652 · Cited by 56

DNA methylation in neurodegenerative disorders: a missing link between genome and environment?

Iraola‐Guzmán, S., Estivill, X., & Rabionet, R. (2011) · Clinical Genetics · doi:10.1111/j.1399-0004.2011.01673.x · Cited by 52

Metabolic syndrome: molecular mechanisms and therapeutic interventions

Zheng, L., Zeng, A., Liu, L., Tian, W., Wang, R., Zhang, L., Hua, H., & Zhao, J. (2025) · Molecular Biomedicine · doi:10.1186/s43556-025-00303-5 · Cited by 48

The Potential Use of DNA Methylation Biomarkers to Identify Risk and Progression of Type 2 Diabetes

Gillberg, L., & Ling, C. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00043 · Cited by 46

The role of epigenetics in hypothalamic energy balance control: implications for obesity

Obri, A., & Claret, M. (2019) · Cell Stress · doi:10.15698/cst2019.07.191 · Cited by 46

DNA Methylation in Cancer: Epigenetic View of Dietary and Lifestyle Factors

Maleknia, M., Ahmadirad, N., Golab, F., Katebi, Y., & Ketabforoush, A. H. M. E. (2023) · Epigenetics Insights · doi:10.1177/25168657231199893 · Cited by 43

Energy, evolution, and human diseases: an overview

Roth, J., Szulc, A. L., & Danoff, A. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.001909 · Cited by 40

Epigenome-wide methylation differences in a group of lean and obese women – A HUNT Study

Kvaløy, K., Page, C. M., & Holmen, T. L. (2018) · Scientific Reports · doi:10.1038/s41598-018-34003-8 · Cited by 39

Impact of parental exercise on epigenetic modifications inherited by offspring: A systematic review

Axsom, J., & Libonati, J. R. (2019) · Physiological Reports · doi:10.14814/phy2.14287 · Cited by 37

Pathways to Aging: The Mitochondrion at the Intersection of Biological and Psychosocial Sciences

Picard, M. A. (2011) · Journal of Aging Research · doi:10.4061/2011/814096 · Cited by 36

Programming of metabolic effects in C57BL/6JxFVB mice by in utero and lactational exposure to perfluorooctanoic acid

van Esterik, J. C. J., Sales, L. B., Dollé, M. E. T., Håkansson, H., Herlin, M., Legler, J., & van der Ven, L. T. M. (2015) · Archives of Toxicology · doi:10.1007/s00204-015-1488-7 · Cited by 35

Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies

Liang, K. X. (2024) · Mitochondrion · doi:10.1016/j.mito.2024.101850 · Cited by 34

Cafeteria diet differentially alters the expression of feeding-related genes through DNA methylation mechanisms in individual hypothalamic nuclei

Lazzarino, G. P., Andreoli, M. F., Rossetti, M. F., Stoker, C., Tschopp, M. V., Luque, E. H., & Ramos, J. G. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.05.005 · Cited by 32

Association of theMTHFR1298A>C (rs1801131) polymorphism with speed and strength sports in Russian and Polish athletes

Zarębska, A., Ahmetov, I. I., Sawczyn, S., Shadrina, A. S., Kaczmarczyk, M., Ficek, K., Maciejewska, A., Sawczuk, M., Leońska‐Duniec, A., Klocek, T., et al. (2013) · Journal of Sports Sciences · doi:10.1080/02640414.2013.825731 · Cited by 32

Toward Precision in Nutrition Therapy

Stoppe, C., Hill, A., Christopher, K. B., & Kristof, A. S. (2024) · Critical Care Medicine · doi:10.1097/ccm.0000000000006537 · Cited by 33

Regulation of MDA-MB-231 cell proliferation by GSK-3β involves epigenetic modifications under high glucose conditions

Gupta, C., Kaur, J., & Tikoo, K. (2014) · Experimental Cell Research · doi:10.1016/j.yexcr.2014.03.019 · Cited by 31

Linoleic and α-linolenic fatty acid consumption over three generations exert cumulative regulation of hepatic expression of genes related to lipid metabolism

Jacometo, C. B., Schmitt, E., Pfeifer, L. F. M., Schneider, A., Bado, F., da Rosa, F. T., Halfen, S., Pino, F. A. B. D., Loor, J. J., Corrêa, M. N., et al. (2014) · Genes & Nutrition · doi:10.1007/s12263-014-0405-7 · Cited by 31

Maternal Western diet increases adiposity even in male offspring of obesity-resistant rat dams: early endocrine risk markers

Frihauf, J. B., Fekete, É. M., Nagy, T. R., Levin, B. E., & Zorrilla, E. P. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00023.2016 · Cited by 32

An epigenetic map of age-associated autosomal loci in northern European families at high risk for the metabolic syndrome

Ali, O., Cerjak, D., Kent, J. W., James, R. G., Blangero, J., Carless, M. A., & Zhang, Y. (2015) · Clinical Epigenetics · doi:10.1186/s13148-015-0048-6 · Cited by 32

Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in prostate cancer patients with excess adiposity—a pilot study

Cheng, Y. F., Monteiro, C., Matos, A., You, J., Fraga, A. M., Pereira, C., Catalán, V., Rodrı́guez, A., Gómez‐Ambrosi, J., Frühbeck, G., et al. (2018) · Clinical Epigenetics · doi:10.1186/s13148-018-0490-3 · Cited by 29

S-Adenosylmethionine-dependent Protein Methylation Is Required for Expression of Selenoprotein P and Gluconeogenic Enzymes in HepG2 Human Hepatocytes

Jackson, M. I., Cao, J., Zeng, H., Uthus, E. O., & Combs, G. F. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.412932 · Cited by 28

Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome

Bucher-Johannessen, C., Page, C. M., Haugen, T. B., Wojewodzic, M. W., Fosså, S. D., Grotmol, T., Haugnes, H. S., & Rounge, T. B. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0764-4 · Cited by 28

Relationship between expression and methylation of obesity-related genes in children

Davé, V. A., Yousefi, P., Huen, K., Volberg, V., & Holland, N. (2015) · Mutagenesis · doi:10.1093/mutage/geu089 · Cited by 26

Electroacupuncture Mimics Exercise-Induced Changes in Skeletal Muscle Gene Expression in Women With Polycystic Ovary Syndrome

Benrick, A., Pillon, N. J., Nilsson, E., Lindgren, E., Krook, A., Ling, C., & Stener‐Victorin, E. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa165 · Cited by 26

The link between hypothalamic epigenetic modifications and long-term feeding control

Benite‐Ribeiro, S. A., Putt, D. A., Soares-Filho, M. C., & dos Santos, J. M. (2016) · Appetite · doi:10.1016/j.appet.2016.08.111 · Cited by 25

Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements

Allum, F., Hedman, Å. K., Shao, X., Cheung, W., Vijay, J., Guénard, F., Kwan, T., Simon, M.-M., Ge, B., de Moura, C. S., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09184-z · Cited by 26

Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients

Chuang, H., Wang, J., Lee, I., Sheu, W. H., & Tan, T. (2016) · Oncotarget · doi:10.18632/oncotarget.7686 · Cited by 23

Comparison of visceral adipose tissue DNA methylation and gene expression profiles in female adolescents with obesity

Barberio, M. D., Nadler, E. P., Sevilla, S., Lu, R., Harmon, B. T., & Hubal, M. J. (2019) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-019-0494-y · Cited by 23

Integration of parallel metabolomics and transcriptomics reveals metabolic patterns in porcine oocytes during maturation

Gao, M., Chen, M., Chen, Q., Zhu, S., Wang, H., Yang, W., Wang, X., Wang, Q., & Gu, L. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1131256 · Cited by 22

Liver DNA methylation analysis in adult female C57BL/6JxFVB mice following perinatal exposure to bisphenol A

van Esterik, J. C. J., Vitins, A. P., Hodemaekers, H. M., Kamstra, J. H., Legler, J., Pennings, J. L. A., Steegenga, W. T., Lute, C., Jelı́nek, J., Issa, J. J., et al. (2014) · Toxicology Letters · doi:10.1016/j.toxlet.2014.10.021 · Cited by 22

Associations between DNA methylation and BMI vary by metabolic health status: a potential link to disparate cardiovascular outcomes

Do, W. L., Nguyen, S., Yao, J., Guo, X., Whitsel, E. A., Demerath, E. W., Rotter, J. I., Rich, S. S., Lange, L. A., Ding, J., et al. (2021) · Clinical Epigenetics · doi:10.1186/s13148-021-01194-3 · Cited by 18

Epigenetics Lights Up the Obesity Field

Martí, A., & Ordovás, J. M. (2011) · Obesity Facts · doi:10.1159/000329847 · Cited by 22

Methylation changes in the peripheral blood of filipinos with type 2 diabetes suggest spurious transcription initiation at TXNIP

Albao, D. S., la Paz, E. M. C., Mercado, M. E., Lirio, A., Mariano, M. C., Kim, S., Yangco, A., Melegrito, J., Wad-asen, K., Gauran, I. I., et al. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz262 · Cited by 19

The Future of Livestock Management: A Review of Real-Time Portable Sequencing Applied to Livestock

Lamb, H. J., Hayes, B. J., Nguyen, L. T., & Ross, E. M. (2020) · Genes · doi:10.3390/genes11121478 · Cited by 21

Maternal Metabolic Health, Lifestyle, and Environment—Understanding How Epigenetics Drives Future Offspring Health

Schwartz, S. S., & Amrom, D. (2023) · Current Diabetes Reviews · doi:10.2174/1573399818666220422085016 · Cited by 20

Liver saturated fat content associates with hepatic DNA methylation in obese individuals

Sehgal, R., Perfilyev, A., Männistö, V., Ågren, J., Nilsson, E., Käkelä, P., Ling, C., de Mello, V. D., & Pihlajamäki, J. (2023) · Clinical Epigenetics · doi:10.1186/s13148-023-01431-x · Cited by 21

Hypermethylation of Cox5a Promoter Is Associated with Mitochondrial Dysfunction in Skeletal Muscle of High Fat Diet-Induced Insulin Resistant Rats

Gong, Y., Liu, Y.-Y., Li, J., Su, L., Yu, S., Zhu, X., Cao, X., & Xiao, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113784 · Cited by 20

Investigation into the promoter DNA methylation of three genes (CAMK1D, CRY2 and CALM2) in the peripheral blood of patients with type 2 diabetes

Cheng, J. R., TANG, L., Hong, Q., Ye, H., Xu, X., Xu, L., Bu, S., Wang, Q., Dai, D., Jiang, D., et al. (2014) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2014.1766 · Cited by 20

Young children’s family history of stuttering and their articulation, language and attentional abilities: An exploratory study

Choi, D., Conture, E. G., Tumanova, V., Clark, C. E., Walden, T. A., & Jones, R. M. (2017) · Journal of Communication Disorders · doi:10.1016/j.jcomdis.2017.11.002 · Cited by 20

Cafeteria diet induces progressive changes in hypothalamic mechanisms involved in food intake control at different feeding periods in female rats

Lazzarino, G. P., Acutain, M. F., Canesini, G., Andreoli, M. F., & Ramos, J. G. (2019) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2019.110542 · Cited by 19

PPARγ and MyoD are differentially regulated by myostatin in adipose-derived stem cells and muscle satellite cells

Zhang, F., Deng, B., Wen, J., Chen, K., Liu, W., Ye, S., Huang, H., Jiang, S., & Xiong, Y. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.01.120 · Cited by 18

Maternal cholesterol levels during gestation: boon or bane for the offspring?

Jayalekshmi, V. S., & Ramachandran, S. (2020) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-020-03916-2 · Cited by 19

‘Omics’‐driven discoveries in prevention and treatment of type 2 diabetes

Gjesing, A. P., & Pedersen, O. B. (2012) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2012.02678.x · Cited by 18

The role of maternal DNA methylation in pregnancies complicated by gestational diabetes

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Braun, K. V. E., Voortman, T., Jong, J. C. K., Jaddoe, V. W. V., Albert Hofman, D., Franco, O. H., & van den Hooven, E. H. (2015) · Journal of Nutrition · doi:10.3945/jn.115.216283 · Cited by 17

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