Cited by 10Medicinal Plants and NeuroprotectionAlzheimer's disease research and treatmentsGinkgo biloba and Cashew Applications

Korean Red Pine (Pinus densiflora) Bark Extract Attenuates Aβ-Induced Cognitive Impairment by Regulating Cholinergic Dysfunction and Neuroinflammation

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Go, Min Ji, Kim, Jong Min, Kang, Jin Yong, Park, Seon Kyeong, Lee, Chang Jun, Kim, Min Ji, Lee, Hyo Rim, Kim, Tae Yoon +3 more·2022·Journal of Microbiology and Biotechnology

Abstract

Min Ji Go, Jong Min Kim, Jin Yong Kang, Seon Kyeong Park, Chang Jun Lee, Min Ji Kim, Hyo Rim Lee, Tae Yoon Kim, Seung Gyum Joo, Dae-Ok Kim, and Ho Jin Heo. J. Microbiol. Biotechnol. 2022;32:1154-67. https://doi.org/10.4014/jmb.2207.07015

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Crossref · 10.4014/jmb.2207.07015

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  • Pinus densiflora extract (15-30 mg/kg) improved cognitive function and reduced AChE activity, while increasing antioxidant levels, reducing neuroinflammation, and enhancing mitochondrial activity in amyloid beta-treated ICR mice.

    “Pinus densiflora extract (15–30 mg/kg) improved cognitive function and reduced AChE activity, while increasing antioxidant levels, reducing neuroinflammation, and enhancing mitochondrial activity in Aβ-treated ICR mice [79].”

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Research works printed but not linked: 1

  1. [18]Kraeuter A-K Guest PC Sarnyai Z 2019 Pre-clinical models 105 111 Springer Berlin, Heidelberg

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Authors
Go, M. J., Kim, J. M., Kang, J. Y., Park, S. K., Lee, C. J., Kim, M. J., Lee, H. R., Kim, T. Y., Joo, S. G., Kim, D.-O., & Heo, H. J.
Affiliations
  • Gyeongsang National University (KR)
  • Kyung Hee University (KR)
Venue
Journal of Microbiology and Biotechnology
Published
2022-08-02
Volume
32
Issue
9
Pages
1154-1167
ISSN
  • 1017-7825 (ISSN-L)
  • 1738-8872
OpenAlex
W4293535893
Cited by
9
References
81
Citations by year
2026: 1 · 2025: 1 · 2024: 1 · 2023: 6
FWCI
2.09
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Journal of Microbiology and Biotechnology (publishedVersion)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
Ministry of Agriculture, Food and Rural Affairs of Korea (202103560001)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Health Sciences › Medicine › Complementary and alternative medicine › Ginkgo biloba and Cashew Applications
Keywords
Korean red pine, Pinus densiflora, bark extract, amyloid-beta, cognitive impairment, cholinergic dysfunction, neuroinflammation, Alzheimer's disease
MeSH terms
NF-KappaB Inhibitor alpha, Neuroinflammatory Diseases, Acetylcholine, Acetylcholinesterase, Adenosine Triphosphate, Animals, Antioxidants, Choline O-Acetyltransferase, Glutathione, Malondialdehyde, Plant Extracts, Superoxide Dismutase, Tumor Necrosis Factor-alpha, Amyloid beta-Peptides, Synaptophysin, Reactive Oxygen Species, Oxidative Stress, Cholinergic Agents, Neuroprotective Agents, Brain-Derived Neurotrophic Factor, Plant Bark, Pinus, bcl-2-Associated X Protein, Mice, Republic of Korea, Cognitive Dysfunction

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