Cited by 227Aging and Gerontology ResearchAging, Health, and DisabilityHealth disparities and outcomes

Paradoxical Trend for Improvement in Mental Health With Aging: A Community-Based Study of 1,546 Adults Aged 21–100 Years

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Thomas, Michael L., Kaufmann, Christopher N., Palmer, Barton W., Depp, Colin A., Martin, Averria Sirkin, Glorioso, Danielle K., Thompson, Wesley K., Jeste, Dilip V.·2016·The Journal of Clinical Psychiatry

Abstract

OBJECTIVE: Studies of aging usually focus on trajectories of physical and cognitive function, with far less emphasis on overall mental health, despite its impact on general health and mortality. This study examined linear and nonlinear trends of physical, cognitive, and mental health over the entire adult lifespan. METHODS: Cross-sectional data were obtained from 1,546 individuals aged 21-100 years, selected using random digit dialing for the Successful AGing Evaluation (SAGE) study, a structured multicohort investigation that included telephone interviews and in-home surveys of community-based adults without dementia. Data were collected from 1/26/2010 to 10/07/2011 targeting participants aged 50-100 years and from 6/25/2012 to 7/15/2013 targeting participants aged 21-100 years with an emphasis on adding younger individuals. Data included self-report measures of physical health, measures of both positive and negative attributes of mental health, and a phone interview-based measure of cognition. RESULTS: Comparison of age cohorts using polynomial regression suggested a possible accelerated deterioration in physical and cognitive functioning, averaging 1.5 to 2 standard deviations over the adult lifespan. In contrast, there appeared to be a linear improvement of about 1 standard deviation in various attributes of mental health over the same life period. CONCLUSIONS: These cross-sectional findings suggest the possibility of a linear improvement in mental health beginning in young adulthood rather than a U-shaped curve reported in some prior studies. Lifespan research combining psychosocial and biological markers may improve our understanding of resilience to mental disability in older age and lead to broad-based interventions promoting mental health in all age groups.

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  1. [55]George LK Life satisfaction in later life Generations: Journal of the American Society on Aging 1986

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Authors
Thomas, M. L., Kaufmann, C. N., Palmer, B. W., Depp, C. A., Martin, A. S., Glorioso, D. K., Thompson, W. K., & Jeste, D. V.
Affiliations
University of California San Diego (US)
Corresponding author
Jeste, Dilip V.
Venue
The Journal of Clinical Psychiatry
Published
2016-08-24
Volume
77
Issue
08
Pages
e1019-e1025
ISSN
0160-6689 (ISSN-L)
OpenAlex
W2516882969
Cited by
225
References
62
Citations by year
2026: 18 · 2025: 18 · 2024: 27 · 2023: 61 · 2022: 26 · 2021: 20 · 2020: 21 · 2019: 16 · 2018: 10 · 2017: 8
FWCI
19.77
Type
journal article
Language
en
Open access
Locations
  • The Journal of Clinical Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • University of California, San Diego
  • National Institute of Mental Health (K23MH102420, R01MH099987, R01MH094151, T32MH019934)
  • Sam and Rose Stein Institute for Research on Aging
Topics
  • Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Aging and Gerontology Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
  • Social Sciences › Health › Health disparities and outcomes
Keywords
mental health, aging, lifespan development, physical health, cognitive function, successful aging, resilience, older adults, early adulthood, U-shaped curve
MeSH terms
Adult, Age Factors, Aged, Aged, 80 and over, Aging, Cross-Sectional Studies, Health Status, Health Surveys, Humans, Mental Health, Middle Aged, Resilience, Psychological, Young Adult, Self Report

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