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Cited by 54

The DOI matches its Crossref record; 181 of the 181 references it cites were found in a registry or an index.

Lipid Droplets as Signaling Platforms Linking Metabolic and Cellular Functions

Arrese, Estela L., Saudale, Fredy Z., Soulages, Jose L.·2014·Lipid Insights
DOI 10.4137/lpi.s11128PMC PMC4161058
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Abstract

The main cells of the adipose tissue of animals, adipocytes, are characterized by the presence of large cytosolic lipid droplets (LDs) that store triglyceride (TG) and cholesterol. However, most cells have LDs and the ability to store lipids. LDs have a well-known central role in storage and provision of fatty acids and cholesterol. However, the complexity of the regulation of lipid metabolism on the surface of the LDs is still a matter of intense study. Beyond this role, a number of recent studies have suggested that LDs have major functions in other cellular processes, such as protein storage and degradation, infection, and immunity. Thus, our perception of LDs has been radically transformed from simple globules of fat to highly dynamic organelles of unexpected complexity. Here, we compiled some recent evidence supporting the emerging view that LDs act as platforms connecting a number of relevant metabolic and cellular functions.

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Research works printed but not linked: 5

  1. Ding Y., 2012, Chin J Biochem Biophys., 44, 394
  2. 10.1194/jlr.R700014-JLR200 · DOI · Paper page
  3. Yu Y.V., 2011, BMC Cell Biol., 12
  4. Hooper C., 2010, BMC Biol., 8
  5. D'Avila H., 2012, Mediators Inflamm., 2012

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Metadata

Authors
Arrese, E. L., Saudale, F. Z., & Soulages, J. L.
Affiliations
Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK, USA.
Venue
Lipid Insights
Publisher
SAGE Publications
Published
2014-01
Volume
7
ISSN
1178-6353
DOI
10.4137/lpi.s11128
PMC
PMC4161058
Cited by
54
References
181
Language
en
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)

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