Current level of consensus on probiotic science-Report of an expert meeting-London, 23 November 2009
Open accessAbstract
The present paper summarizes the consensus views of a group of 9 European clinicians and scientists on the current state of scientific knowledge on probiotics, covering those areas where there is substantial evidence for beneficial effects and those where the evidence base is poor or inconsistent. There was general agreement that probiotic effects were species and often strain specific. The experts agreed that some probiotics were effective in reducing the incidence and duration of rotavirus diarrhoea in infants, antibiotic-associated diarrhoea in adults and, for certain probiotics, Clostridium difficile infections. Some probiotics are associated with symptomatic improvements in irritable bowel syndrome and alleviation of digestive discomfort. Probiotics can reduce the frequency and severity of necrotizing enterocolitis in premature infants and have been shown to regulate intestinal immunity. Several other clinical effects of probiotics, including their role in inflammatory bowel disease, atopic dermatitis, respiratory or genito-urinary infections or H.pylori adjuvant treatment were thought promising but inconsistent.
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The number of probiotic bacteria that guarantee a beneficial effect in humans is not standardized and is dependent on the tension and effect.
“The number of probiotic bacteria that guarantee a beneficial effect in humans is not standardized and is dependent on the tension and effect [55].”
From Probiotic and Antifungal Attributes of Lactic Acid Bacteria Isolates from Naturally Fermented Brazilian Table Olives (2022) · cites this paper as [55]
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- Authors
- Rowland, I. R., Capurso, L., Collins, K., Cummings, J., Delzenne, N., Goulet, O., Guarner, F., Marteau, P., & Meier, R.
- Affiliations
- University of Reading (GB)
- Ospedale San Filippo Neri (IT)
- University College Cork (IE)
- Ninewells Hospital (GB)
- UCLouvain (BE)
- Hôpital Necker-Enfants Malades (FR)
- Vall d'Hebron Hospital Universitari (ES)
- Hôpital Lariboisière (FR)
- Corresponding author
- Rowland, Ian R.
- Venue
- Gut Microbes
- Publisher
- Informa UK Limited
- Published
- 2010-11
- Volume
- 1
- Issue
- 6
- Pages
- 436-439
- ISSN
- 1949-0976 (ISSN-L)
- 1949-0984
- PMC
- PMC3056112
- OpenAlex
- W1772983474
- Cited by
- 109
- References
- 37
- Citations by year
- 2026: 2 · 2024: 6 · 2023: 4 · 2022: 5 · 2021: 8 · 2020: 12 · 2019: 8 · 2018: 6 · 2017: 8 · 2016: 8 · 2015: 6 · 2014: 9 · 2013: 8 · 2012: 13
- FWCI
- 13.25
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- Gut Microbes (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DIAL (Catholic University of Leuven) (submittedVersion, other-oa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- probiotics, strain-specific effects, antibiotic-associated diarrhea, Clostridium difficile infection, irritable bowel syndrome, necrotizing enterocolitis, preterm infants, intestinal immunity, inflammatory bowel disease, atopic dermatitis, Helicobacter pylori, respiratory infections, genitourinary infections, expert consensus
- MeSH terms
- Adult, Bacteria, Clostridium Infections, Diarrhea, Diet, Dyspepsia, Humans, Infant, Intestines, Rotavirus Infections, Incidence, Treatment Outcome, Immunity, Mucosal, Probiotics, Irritable Bowel Syndrome
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