The IRF family of transcription factors: Inception, impact and implications in oncogenesis

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

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Papillomaviruses and cancer: from basic studies to clinical application

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IRF-7 is the master regulator of type-I interferon-dependent immune responses

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IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

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IRF Family of Transcription Factors as Regulators of Host Defense

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Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

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Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

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Inflammation meets cancer, with NF-κB as the matchmaker

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Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction

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The IRF Family Transcription Factors in Immunity and Oncogenesis

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Analysis of differentially expressed genes and the promoters in bovine endometrium throughout estrus cycle and early pregnancy

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TNFα mediated ceramide generation triggers cisplatin induced apoptosis in B16F10 melanoma in a PKCδ independent manner

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DIVERSITY in binding, regulation, and evolution revealed from high-throughput ChIP

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LSD1 Cooperates with Noncanonical NF-κB Signaling to Regulate Marginal Zone B Cell Development

Haines, R. R., Scharer, C. D., Lobby, J. L., & Boss, J. M. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900654 · Cited by 19

Functional Analysis of IRF1 Reveals its Role in the Activation of the Type I IFN Pathway in Golden Pompano, Trachinotus ovatus (Linnaeus 1758)

Zhu, K.-C., Zhang, N., Liu, B.-S., Guo, L. J., Guo, H., Jiang, S., & Zhang, D. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072652 · Cited by 19

Epigenetic priming of immune/inflammatory pathways activation and abnormal activity of cell cycle pathway in a perinatal model of white matter injury

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Interferon regulatory factor 2 plays a positive role in interferon gamma expression in golden pompano, Trachinotus ovatus (Linnaeus 1758)

Zhu, K.-C., Liu, B.-S., Zhang, N., Guo, H., Guo, L. J., Jiang, S., & Zhang, D. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.12.006 · Cited by 18

Functional characterization of interferon regulatory factor 5 and its role in the innate antiviral immune response

Ai, K., Luo, K., Xia, L., Gao, W., Hu, W., Qi, Z., & Xu, Q. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.10.042 · Cited by 17

microRNA-144/451 decreases dendritic cell bioactivity via targeting interferon-regulatory factor 5 to limit DSS-induced colitis

Lin, Z., Xie, X., Gu, M. J., Chen, Q., Lu, G., Jia, X., Xiao, W., Zhang, J., Yu, D., & Gong, W. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.928593 · Cited by 17

The molecular mechanism of dsDNA sensing through the cGAS-STING pathway

Shinde, O., & Li, P. (2024) · Advances in immunology · doi:10.1016/bs.ai.2024.02.003 · Cited by 16

Identification, characterization and expression in response to Aeromonas hydrophila challenge of five interferon regulatory factors in Megalobrama amblycephala

Zhan, F., Jakovlić, I., & Wang, W. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.10.037 · Cited by 17

XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7

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MicroRNA-301a (miR-301a) is induced in hepatocellular carcinoma (HCC) and down- regulates the expression of interferon regulatory factor-1

Dong, K., Du, Q., Cui, X., Wan, P., Kaltenmeier, C., Luo, J., Yan, B., Yan, Y., & Geller, D. A. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.01.034 · Cited by 16

Up-Regulation of Interferon Regulatory Factor 3 Involves in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats

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Stimulator of interferon gene (STING) and interferon regulatory factor (IRF) are crucial for shrimp antiviral defense against WSSV infection

Amparyup, P., Charoensapsri, W., Soponpong, S., Jearaphunt, M., Wongpanya, R., & Tassanakajon, A. (2021) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2021.08.016 · Cited by 15

IRF2 enhances RANKL-induced osteoclast differentiation via regulating NF-κB/NFATc1 signaling

Kim, I., Kim, J. H., Kim, K., Seong, S., Lee, K., & Kim, N. (2021) · BMB Reports · doi:10.5483/bmbrep.2021.54.9.070 · Cited by 15

The Role of Interferon Regulatory Factors in Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis

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Digital analysis and epigenetic regulation of the signature of rejection in colorectal cancer

Koelzer, V. H., Sokol, L., Zahnd, S., Christe, L., Dawson, H., Berger, M. D., Inderbitzin, D., Zlobec, I., & Lugli, A. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1288330 · Cited by 15

Characterization and expression analysis of the interferon regulatory factor (IRF) gene family in zig-zag eel (Mastacembelus armatus) against Aeromonas veronii infection

Han, C., Huang, W., Peng, S., Zhou, J., Zhan, H., Li, W., Gong, J., & Li, Q. (2022) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2022.104622 · Cited by 15

Knockdown of IRF6 Attenuates Hydrogen Dioxide-Induced Oxidative Stress via Inhibiting Mitochondrial Dysfunction in HT22 Cells

Guo, X., Chen, B., Lv, J.-M., Lei, Q., Pan, Y., & Yang, Q. (2015) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-015-0301-8 · Cited by 15

Global characterization and expression analysis of interferon regulatory factors in response to Aeromonas hydrophila challenge in Chinese soft-shelled turtle (Pelodiscus sinensis)

Liu, T., Han, Y., Chen, S., & Zhao, H. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.07.013 · Cited by 14

CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity

House, I. G., Derrick, E. B., Sek, K., Chen, A. X. Y., Li, J., Lai, J., Todd, K. L., Munoz, I., Michie, J., Chan, C. W., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113014 · Cited by 15

Identification and characterization of the lamprey IRF gene

Pang, Y., Liu, S., Zheng, Z., Liu, X., & Li, Q. (2015) · Immunology Letters · doi:10.1016/j.imlet.2015.02.006 · Cited by 14

Functional characterization of interferon regulatory factor 2 and its role in the transcription of interferon a3 in golden pompano Trachinotus ovatus (Linnaeus 1758)

Zhu, K.-C., Guo, H., Zhang, N., Guo, L. J., Liu, B.-S., Jiang, S., & Zhang, D. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.07.045 · Cited by 14

Acetylation of interferon regulatory factor‐5 suppresses androgen receptor and downregulates expression of Sox2

Acidereli, H., Turut, F. A., & Çevik, Ö. D. (2021) · Cell Biochemistry and Function · doi:10.1002/cbf.3633 · Cited by 13

Metastatic Lesions with and without Interleukin-18–Dependent Genes in Advanced-Stage Melanoma Patients

Crende, O., Sabatino, M., Valcárcel, M., Carrascal, T., Riestra, P., López‐Guerrero, J. A., Nagore, E., Mandruzzato, S., Wang, E., Marincola, F. M., et al. (2013) · American Journal Of Pathology · doi:10.1016/j.ajpath.2013.03.026 · Cited by 13

A systems-based framework to computationally describe putative transcription factors and signaling pathways regulating glycan biosynthesis

Groth, T., Gunawan, R., & Neelamegham, S. (2021) · Beilstein Journal of Organic Chemistry · doi:10.3762/bjoc.17.119 · Cited by 13

MicroRNAs in the Regulation of RIG-I-like Receptor Signaling Pathway: Possible Strategy for Viral Infection and Cancer

Chen, D., Ji, Q., Liu, J., Cheng, F., Zheng, J., Ma, Y., He, Y., Zhang, J., & Song, T. (2023) · Biomolecules · doi:10.3390/biom13091344 · Cited by 15

Interferon regulatory factors: Where to stand in transplantation

Assadiasl, S., Shahi, A., Salehi, S., Afzali, S., & Amirzargar, A. (2018) · Transplant Immunology · doi:10.1016/j.trim.2018.10.001 · Cited by 13

Identification and characterization of IRF9 from black carp Mylopharyngodon piceus

Lu, X., Liu, J., Yan, J., Wu, H., & Feng, H. (2019) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2019.103528 · Cited by 13

Functional characterization of IRF8 regulation of type II IFN in golden pompano (Trachinotus ovatus)

Zhu, K.-C., Guo, H., Zhang, N., Liu, B.-S., Guo, L. J., Jiang, S., & Zhang, D. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.08.060 · Cited by 12

Anisodamine Enhances Macrophage M2 Polarization through Suppressing G9a-Mediated Interferon Regulatory Factor 4 Silencing to Alleviate Lipopolysaccharide-Induced Acute Lung Injury

Zhang, Y., Song, D., Peng, Z., Wang, R., Li, K., Ren, H. G., Sun, X., Du, N., & Tang, S. (2022) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.121.001019 · Cited by 12

The regulatory mechanisms of IRF7 mediated by the type I IFN signalling pathway against Streptococcus iniae in yellowfin seabream, Acanthopagrus latus (Hottuyn, 1782)

Guo, H., He, H.-X., Liu, B.-S., Zhang, N., Zhu, K.-C., & Zhang, D. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125635 · Cited by 12

Prognostic value of IRF-2 expression in colorectal cancer

Mei, Z., Wang, G., Liang, Z., Cui, A., Xu, A., Liu, Y., Liu, C., Yang, Y., & Cui, L. (2017) · Oncotarget · doi:10.18632/oncotarget.17163 · Cited by 12

IFNAR1 Is a Predictor for Overall Survival in Colorectal Cancer and Its mRNA Expression Correlated With IRF7 But Not TLR9

Chang, L., Fan, C., Tseng, W., Chein, H., Hsieh, T.-Y., Chen, J., Hwang, C., & Hua, C. (2014) · Medicine · doi:10.1097/md.0000000000000349 · Cited by 12

Characterization of the IRF2 proteins isolated from the deep-sea mussel Bathymodiolus platifrons and the shallow-water mussel Modiolus modiolus

Huang, B., Meng, J., Yang, M., Xu, F., Li, X., Li, L., & Zhang, G. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.01.015 · Cited by 11

Assessment of histone tail modifications and transcriptional profiling during colon cancer progression reveals a global decrease in H3K4me3 activity

Triff, K., McLean, M. W., Konganti, K., Pang, J., Callaway, E. S., Zhou, B., Ivanov, I. V., & Chapkin, R. S. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.03.009 · Cited by 11

Index and biological spectrum of accessible DNA elements in the human genomePreprint

Meuleman, W. R. A., Muratov, A., Rynes, E., Halow, J. M., Lee, K., Bates, D., Diegel, M., Dunn, D., Neri, F. J., Teodosiadis, A., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/822510 · Cited by 12

A Comprehensive Analysis of Interferon Regulatory Factor Expression: Correlation with Immune Cell Infiltration and Patient Prognosis in Endometrial Carcinoma

Lu, X., Li, R., Ying, Y., & Zhang, W. (2022) · BioMed Research International · doi:10.1155/2022/7948898 · Cited by 10

Key role of interferon regulatory factor 1 (IRF-1) in regulating liver disease: progress and outlook

Chen, T., Li, S., Deng, D., Zhang, W., Zhang, J., & Shen, Z. (2024) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b2300159 · Cited by 10

DFF-ChIP: a method to detect and quantify complex interactions between RNA polymerase II, transcription factors, and chromatin

Spector, B. M., Santana, J. F., Pufall, M. A., & Price, D. H. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae760 · Cited by 10

IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas

Tong, S., Ye, L., Xu, Y., Sun, Q., Gao, L., Cai, J., Ye, Z., Tian, D., & Chen, Q. (2022) · Translational Oncology · doi:10.1016/j.tranon.2022.101544 · Cited by 10

Scallop interferon regulatory factor 1 interacts with myeloid differentiation primary response protein 88 and is crucial for antiviral innate immunity

Liu, W., Li, F., Ma, J., Chen, J., Huang, B., Li, L., Fan, N., Wang, X., Zheng, Y., Wang, X., et al. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.09.248 · Cited by 10

Nuclear import of IRF11 via the importin α/β pathway is essential for its antiviral activity

Li, W., Zhao, G., Jiao, Z., Xiang, C., Liang, Y., Huang, W., Nie, P., & Huang, B. (2023) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2023.104649 · Cited by 10

IRF5 regulates unique subset of genes in dendritic cells during West Nile virus infection

Chow, K. T., Driscoll, C. B., Loo, Y., Knoll, M. L., & Gale, M. (2018) · Journal of Leukocyte Biology · doi:10.1002/jlb.ma0318-136rrr · Cited by 10

IKKε-like plays an important role in the innate immune signaling of the Pacific oyster (Crassostrea gigas)

Huang, B., Tang, X., Zhang, L., Li, L., Wang, W., Liu, M., & Zhang, G. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.07.074 · Cited by 10

Functional characterization of goose IRF1 in IFN induction and anti-NDV infection

Lin, Z., Wang, J., Zhang, N., Yi, J., Wang, Z., Ma, J., Wang, H., Yan, Y., Qian, K., Sun, J., et al. (2022) · Veterinary Research · doi:10.1186/s13567-022-01046-9 · Cited by 10

Central IRF4/5 Signaling Are Critical for Microglial Activation and Impact on Stroke Outcomes

Ngwa, C., Mamun, A. A., Qi, S., Sharmeen, R., Conesa, M. P. B., Ganesh, B. P., Manwani, B., & Liu, F. (2023) · Translational Stroke Research · doi:10.1007/s12975-023-01172-2 · Cited by 11

Coevolution of HTLV-1-HBZ, Tax, and proviral load with host IRF-1 and CCNA-2 in HAM/TSP patients

Saffari, M., Rahimzada, M., Mirhosseini, A., Ghezeldasht, S. A., Valizadeh, N., Moshfegh, M., Moradi, M.-T., & Rezaee, S. A. (2022) · Infection Genetics and Evolution · doi:10.1016/j.meegid.2022.105337 · Cited by 9

The IRF transcription factor family in type I interferon-mediated antiviral immunity and associated diseases

Yanai, H., & Taniguchi, T. (2026) · Immunity & Inflammation · doi:10.1007/s44466-025-00019-9 · Cited by 9

Functional domains and amino acid residues of Japanese eel IRF1, AjIRF1, regulate its nuclear import and IFN/Mx promoter activation

Li, W., Ling, L., Wang, Z., Liang, Y., Huang, W., Nie, P., & Huang, B. (2020) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2020.103923 · Cited by 9

A molluscan IRF interacts with IKKα/β family protein and modulates NF-κB and MAPK activity

Ma, J., Chen, J., Cui, J., Liu, W., Qu, Y., Lu, X., Wang, A., Huang, B., & Wang, X. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.128319 · Cited by 9

Surgical Strikes on Host Defenses: Role of the Viral Protease Activity in Innate Immune Antagonism

Chin, C. V., & Saeed, M. (2022) · Pathogens · doi:10.3390/pathogens11050522 · Cited by 8

KMT2D Loss Promotes Head and Neck Squamous Carcinoma Through Enhancer Reprogramming and Modulation of Immune MicroenvironmentPreprint

Callahan, S. C., Divenko, M., Barrodia, P., Singh, A. K., Arslan, E., Liu, Z., Yang, J., Anvar, N. E., Amit, M., Xie, T., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.09.21.461314 · Cited by 9

Transcriptomic response of lumpfish (Cyclopterus lumpus) head kidney to viral mimic, with a focus on the interferon regulatory factor family

Emam, M., Kumar, S., Eslamloo, K., Caballero‐Solares, A., Hall, J. R., Xue, X., Paradis, H., Gendron, R. L., Santander, J., & Rise, M. L. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1439465 · Cited by 8

Phototherapy Restores Deficient Type I IFN Production and Enhances Antitumor Responses in Mycosis Fungoides

Yu, Z., Vieyra-Garcia, P. A., Benezeder, T., Crouch, J. D., Kim, I. R., O’Malley, J. T., Devlin, P. M., Gehad, A. E., Zhan, Q., Gudjonsson, J. E., et al. (2023) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2023.06.212 · Cited by 8

Capsaicin Enhances Temozolomide-Resistant Glioblastoma Cells’ Chemosensitivity and Ferroptosis through FHOD1/IRF2 Downregulation

Hacıoğlu, C. (2024) · Journal of Food Biochemistry · doi:10.1155/2024/8464817 · Cited by 8

Radiogenomics-Based Risk Prediction of Glioblastoma Multiforme with Clinical Relevance

Qian, X., Tan, H., Liu, X., Zhao, W., Chan, M. D., Kim, P., & Zhou, X. (2024) · Genes · doi:10.3390/genes15060718 · Cited by 9

IRF4 expression is low in Philadelphia negative myeloproliferative neoplasms and is associated with a worse prognosis

Cumbo, C., Tarantini, F., Anelli, L., Zagaria, A., Redavid, I., Minervini, C. F., Coccaro, N., Tota, G., Ricco, A., Parciante, E., et al. (2021) · Experimental Hematology and Oncology · doi:10.1186/s40164-021-00253-y · Cited by 8

Interferon Regulatory Factor Family Genes: At the Crossroads between Immunity and Head and Neck Squamous Carcinoma

Liu, S., & Wang, Z. (2022) · Disease Markers · doi:10.1155/2022/2561673 · Cited by 8

Apolipoprotein L1 is transcriptionally regulated by SP1, IRF1 and IRF2 in hepatoma cells

Wang, D., Yu, Z., He, Z., Liao, J., Shen, X., Zhu, P., Chen, W., Lin, X., & Xu, S. (2020) · FEBS Letters · doi:10.1002/1873-3468.13887 · Cited by 8

IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas

Sarı, G., Dhatchinamoorthy, K., Orellano, L. A. A., Ferreira, L. M., Brehm, M. A., & Rock, K. L. (2024) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-03187-5 · Cited by 7

A new transcription factor ATG10S activates IFNL2 transcription by binding at an IRF1 site in HepG2 cells

Zhang, M., Zhao, Q., & Zhang, J. (2020) · Autophagy · doi:10.1080/15548627.2020.1719681 · Cited by 7

Expression of interferon regulatory factors (IRF-1 and IRF-2) during radiation-induced damage and regeneration of bone marrow by transplantation in mouse

Ahamad, N., & Rath, P. C. (2018) · Molecular Biology Reports · doi:10.1007/s11033-018-4508-x · Cited by 7

Knockout of IRF3 and IRF7 genes by CRISPR/Cas9 technology enhances porcine virus replication in the swine testicular (ST) cell line

Sun, X., Wang, J., Mou, C., Shi, K., Bao, W., & Chen, Z. (2023) · Biotechnology Journal · doi:10.1002/biot.202300389 · Cited by 6

The involvement of interferon regulatory factor 8 in regulating the proliferation of haemocytes in oyster Crassostrea gigas

Yu, Z. Y., Qiao, X., Yu, S., Gu, X., Jin, Y., Tang, C., Niu, J., Wang, L., & Song, L. (2024) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2024.105172 · Cited by 6

Functional characterization of irf3 against viral hemorrhagic septicemia virus infection using a CRISPR/Cas9-mediated zebrafish knockout model

Sellaththurai, S. R., Jung, S., Nadarajapillai, K., Kim, M., & Lee, J. (2024) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2024.105208 · Cited by 6

Type I Interferon Activates PD-1 Expression through Activation of the STAT1-IRF2 Pathway in Myeloid Cells

Liang, L., Yang, Y., Deng, K., Wu, Y., Li, Y., Bai, L., Wang, Y., & Lu, C. (2024) · Cells · doi:10.3390/cells13131163 · Cited by 6

Structural and expression analysis of golden pompano Trachinotus ovatus IRF5 and its role in regulation of type I IFN

Zhu, K.-C., Guo, H., Zhang, N., Liu, B.-S., Guo, L. J., Jiang, S., & Zhang, D. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.12.058 · Cited by 6

The molecular basis for the development of adult T‐cell leukemia/lymphoma in patients with an IRF4K59R mutation

Sundararaj, S., Seneviratne, S., Williams, S. J., Enders, A., & Casarotto, M. G. (2021) · Protein Science · doi:10.1002/pro.4260 · Cited by 5

Interferon Regulatory Factors Functioned as Activators of the Interferon Pathway in the Scallop Chlamys farreri

Hu, N., Lian, S., Zhu, X., Chen, X., Sun, F., Zhang, L., Wang, S., Bao, Z., & Hu, J. (2022) · Frontiers in Marine Science · doi:10.3389/fmars.2022.865707 · Cited by 6

Aged Callus Skeletal Stem/Progenitor Cells Contain an Inflammatory Osteogenic Population With Increased IRF and NF-κB Pathways and Reduced Osteogenic Potential

Lin, X., Zhang, H., Liu, J., Wu, C., McDavid, A., Boyce, B. F., & Xing, L. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.806528 · Cited by 6

CfIRF8-like interacts with the TBK1/IKKε family protein and regulates host antiviral innate immunity

Li, F., Liu, W., Chen, J., Huang, B., Zheng, Y., Ma, J., Cai, S., Li, L., Liu, F., Wang, X., et al. (2022) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2022.108497 · Cited by 6

Interferon Regulatory Factor 4 (IRF4) Plays a Key Role in Osteoblast Differentiation of Postmenopausal Osteoporosis

Wu, X., Yang, C., Chen, X., Shan, Z., & Wu, X. (2024) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2903115 · Cited by 6

Association of interferon regulatory factor 4 gene polymorphisms rs12203592 and rs872071 with skin cancer and haematological malignancies susceptibility: a meta-analysis of 19 case–control studies

Wang, S., Yan, Q., Chen, P., Zhao, P., & Gu, A. (2014) · BMC Cancer · doi:10.1186/1471-2407-14-410 · Cited by 6

Disrupted cooperation between transcription factors across diverse cancer types

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Recombinant human interferon regulatory factor-1 (IRF-1) protein expression and solubilisation study in Escherichia coli

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Integrative analysis of AR‐mediated transcriptional regulatory network reveals IRF1 as an inhibitor of prostate cancer progression

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Characterization of Red Sea Bream (Pagrus major) Interferon Regulatory Factor 5 and 6 Genes and Their Expression in Response to RSIV Infection

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Correlative analysis of transcriptome and proteome in Penaeus vannamei reveals key signaling pathways are involved in IFN-like antiviral regulation mediated by interferon regulatory factor (PvIRF)

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Comprehensive network modeling approaches unravel dynamic enhancer-promoter interactions across neural differentiation

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Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

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Single cell transcriptomics identifies distinct choroid cell populations involved in visually guided eye growth

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Cyproheptadine, an epigenetic modifier, exhibits anti-tumor activity by reversing the epigenetic silencing of IRF6 in urothelial carcinoma

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Penaeus monodon Interferon Regulatory Factor (PmIRF) Activates IFNs and Antimicrobial Peptide Expression via a STING-Dependent DNA Sensing Pathway

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The Innate Immune System and Fever under Redox Control: A Narrative Review

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The characterization of a novel IRF8-like homolog and its role in the immune modulation of the sea urchin Strongylocentrotus intermedius

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The Dynamically Evolving Cell States and Ecosystem from Benign Nevi to Melanoma

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Macrophage defects

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Identification of Immune-Related Genes for Risk Stratification in Multiple Myeloma Based on Whole Bone Marrow Gene Expression Profiling

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Potentially functional genetic variants in interferon regulatory factor family genes are associated with colorectal cancer survival

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Double-Hit Lymphoma Demonstrating t(6;14;18)(p25;q32;q21), Suggesting Two Independent Dual-Hit Translocations, MYC/BCL-2 and IRF4/BCL-2

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Anti-virus effects of interferon regulatory factors (IRFs) identified in ascidian Ciona savignyi

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IRF-7: an Antiviral Factor and Beyond

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Cloning and characterizing of the murine IRF-3 gene promoter region

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The Role of Epigenetics in Cervical Cancer

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Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-κB

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Evolutionary and functional conservation of IRF7 in the Tibetan frog Nanorana parkeri

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Crystal Structures of DNA-bound Fish IRF10 and IRF11 Reveal the Determinants of IFN Regulation

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Uncovering selection pressures on the IRF gene family in bats’ immune system

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Regulation of immunity and oncogenesis by the IRF transcription factor family

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The interferon regulatory factors and oncogenesis

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The IRF Family Transcription Factors in Immunity and Oncogenesis

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Genetic and Epigenetic Regulation of Interferon Regulatory Factor Expression: Implications in Human Malignancies

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