Diet-related complications according to the timing of enteral nutrition support in patients who recovered from out-of-hospital cardiac arrest: a propensity score matched analysis
Open accessAbstract
Background: A proper nutritional plan for resuscitated patients is important in intensive care; however, specific nutritional guidelines have not yet been established. This study aimed to determine the incidence of diet-related complications that were affected by the timing of enteral nutrition in resuscitated patients after cardiac arrest.Methods: This retrospective and 1:1 propensity score matching study involved patients who recovered after nontraumatic, out-of-hospital cardiac arrest at a tertiary hospital. Patients were divided into an early enteral nutrition support (ENS) group and a delayed enteral nutrition support (DNS) group according to the nutritional support time within 48 hours after admission. The incidence of major clinical complications was compared between the groups.Results: A total of 46 patients (ENS, 23; DNS, 23) were enrolled in the study. There were no differences in body mass index, comorbidity, and time of cardiopulmonary resuscitation between the two groups. There were 9 patients (ENS: 4, DNS: 5) with aspiration pneumonia; 4 patients (ENS: 2, DNS: 2) with regurgitation; one patient (ENS: 0, DNS: 1) with ileus; 21 patients (ENS: 10, DNS: 11) with fever; 13 patients (ENS: 8, DNS: 5) with hypoglycemia; and 20 patients (ENS: 11, DNS: 9) with hyperglycemia. The relative risk of each complication during post-resuscitation care was no different between groups.Conclusions: There was a similar incidence of diet-related complications during post cardiac arrest care according to the timing of enteral nutrition.
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Newer data demonstrated no difference in complications with early enteral nutrition (<48 hours) even during targeted temperature management.
“newer data demonstrated no difference in complications with early EN (<48 hours) even during targeted temperature management.19,174–177”
From Malnutrition and Cachexia in Inpatients With Acute Cardiac Conditions: A Scientific Statement From the American Heart Association (2026) · cites this paper as [174]
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- Authors
- Kim, G. W., Roh, Y.-I., Cha, K.-C., Hwang, S. O., Han, J. H., & Jung, W. J.
- Affiliations
- Yonsei University (KR)
- Corresponding author
- Jung, Woo Jin
- Venue
- Acute and Critical Care
- Published
- 2022-11-30
- Volume
- 37
- Issue
- 4
- Pages
- 610-617
- ISSN
- 2586-6052 (ISSN-L)
- 2586-6060
- PMC
- PMC9732188
- OpenAlex
- W4307331215
- Cited by
- 4
- References
- 27
- Citations by year
- 2026: 3 · 2024: 1
- FWCI
- 0.15
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Acute and Critical Care (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
- Health Sciences › Health Professions › Radiological and Ultrasound Technology › Family and Patient Care in Intensive Care Units
- Keywords
- out-of-hospital cardiac arrest, enteral nutrition, nutritional support timing, aspiration pneumonia, regurgitation, ileus, fever, hypoglycemia, hyperglycemia, post-resuscitation care, intensive care nutrition
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