Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity

Central nervous system control of food intake

Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451

A Potential Decline in Life Expectancy in the United States in the 21st Century

Olshansky, S. J., Passaro, D. J., Hershow, R. C., Layden, J., Carnes, B. A., Brody, J., Hayflick, L., Butler, R. N., Allison, D. B., & Ludwig, D. S. (2005) · New England Journal of Medicine · doi:10.1056/nejmsr043743 · Cited by 2,612

Long-term mortality after gastric bypass surgery

Adams, T. D., Gress, R. E., Smith, S. C., Halverson, R. C., Simper, S. C., Rosamond, W. D., LaMonte, M. J., Stroup, A. M., & Hunt, S. C. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa066603 · Cited by 2,572

Gut hormone PYY3-36 physiologically inhibits food intake

Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., Wren, A. M., Brynes, A. E., Low, M. J., Ghatei, M. A., et al. (2002) · Nature · doi:10.1038/nature00887 · Cited by 2,351

The human orbitofrontal cortex: linking reward to hedonic experience

Kringelbach, M. L. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1747 · Cited by 2,180

A role for glucagon-like peptide-1 in the central regulation of feeding

Turton, M. D., O'Shea, D., Gunn, I., Beak, S. A., Edwards, C. M. B., Meeran, K., Choi, S. J., Taylor, G. M., Heath, M. M., Lambert, P. D., et al. (1996) · Nature · doi:10.1038/379069a0 · Cited by 1,950

A Potential Decline in Life Expectancy in the United States in the 21st Century

Olshansky, S. J., Passaro, D. J., Hershow, R. C., Layden, J. E., Carnes, B. A., Brody, J. A., Hayflick, L., Butler, R. N., Allison, D. B., & Ludwig, D. S. (2005) · Obstetrical & Gynecological Survey · doi:10.1097/01.ogx.0000167407.83915.e7 · Cited by 1,947

Glucagon-like peptide-1 7–36: a physiological incretin in man

Kreymann, B., Ghatei, M. A., Williams, G., & Bloom, S. R. (1987) · The Lancet · doi:10.1016/s0140-6736(87)91194-9 · Cited by 1,928

Brain Lesions, Obesity, and Other Disturbances in Mice Treated with Monosodium Glutamate

Olney, J. (1969) · Science · doi:10.1126/science.164.3880.719 · Cited by 1,885

Inhibition of Food Intake in Obese Subjects by Peptide YY 3–36

Batterham, R. L., Cohen, M. A., Ellis, S. M., Le Roux, C. W., Withers, D. J., Frost, G. S., Ghatei, M. A., & Bloom, S. R. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030204 · Cited by 1,604

A comprehensive insight into the effect of glutamine supplementation on metabolic variables in diabetes mellitus: a systematic review

Vayghan, H. J., Varshosaz, P., Hajizadeh‐Sharafabad, F., Razmi, H., Amirpour, M., Tavakoli‐Rouzbehani, O. M., Alizadeh, M., & Maleki, V. (2020) · Nutrition & Metabolism · doi:10.1186/s12986-020-00503-6 · Cited by 44

Supplementation of Lactobacillus plantarum Improves Markers of Metabolic Dysfunction Induced by a High Fat Diet

Martinic, A., Barouei, J., Bendiks, Z., Mishchuk, D. O., Heeney, D. D., Martin, R. J., Marco, M. L., & Slupsky, C. M. (2018) · Journal of Proteome Research · doi:10.1021/acs.jproteome.8b00282 · Cited by 42

Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis

Milliken, B. T., Elfers, C., Chepurny, O. G., Chichura, K. S., Sweet, I. R., Borner, T., Hayes, M. R., Jonghe, B. C. D., Holz, G. G., Roth, C. L., et al. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.0c01783 · Cited by 39

Advances in the mechanism of metformin with wide-ranging effects on regulation of the intestinal microbiota

Wang, Y., Jia, X., & Cong, B. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1396031 · Cited by 42

Low carbohydrate ketogenic therapy as a metabolic treatment for binge eating and ultraprocessed food addiction

Sethi, S., Sinha, A., & Gearhardt, A. N. (2020) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000571 · Cited by 36

Adipose and non-adipose perspectives of plant derived natural compounds for mitigation of obesity

Borah, A. K., Sharma, P., Singh, A., Kalita, K. J., Saha, S., & Borah, J. C. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114410 · Cited by 35

Identification, expression analysis, and functional characterization of peptide YY in chickens (Gallus gallus domesticus)

Aoki, K., Kondo, M., Okuda, M., Saneyasu, T., Honda, K., & Kamisoyama, H. (2016) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2016.04.021 · Cited by 35

Changes in appetite-regulating hormones following food intake are associated with changes in reported appetite and a measure of hedonic eating in girls and young women with anorexia nervosa

Mancuso, C., Izquierdo, A. M., Slattery, M. J., Becker, K. R., Plessow, F., Thomas, J. J., Eddy, K. T., Lawson, E. A., & Misra, M. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.104556 · Cited by 41

Bariatric surgery – time to replace with GLP-1?

Webb, D., Abrahamsson, N., Sundbom, M., & Hellström, P. M. (2017) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365521.2017.1293154 · Cited by 38

Can We Selectively Reduce Appetite for Energy-Dense Foods? An Overview of Pharmacological Strategies for Modification of Food Preference Behavior

Bojanowska, E., & Ciosek, J. (2015) · Current Neuropharmacology · doi:10.2174/1570159x14666151109103147 · Cited by 35

Influencia multisensorial sobre la conducta alimentaria: ingesta hedónica

de Eguilaz, M. H. R., Aldabe, B. M. D. M., Almiron‐Roig, E., Pérez-Díez, S., San-Cristóbal, R., Navas‐Carretero, S., & Martínez, J. A. (2017) · Endocrinología Diabetes y Nutrición · doi:10.1016/j.endinu.2017.09.008 · Cited by 34

Pharmacology of dipeptidyl peptidase-4 inhibitors and its use in the management of metabolic syndrome: a comprehensive review on drug repositioning

Rameshrad, M., Razavi, B. M., Ferns, G. A. A., & Hosseinzadeh, H. (2019) · DARU Journal of Pharmaceutical Sciences · doi:10.1007/s40199-019-00238-7 · Cited by 34

Anhedonia induced by high-fat diet in mice depends on gut microbiota and leptin

Hassan, A. M., Mancano, G., Kashofer, K., Liebisch, G., Farzi, A., Zenz, G., Claus, S. P., & Holzer, P. D. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2020.1751508 · Cited by 36

Nutritional Ketosis as a Potential Treatment for Alcohol Use Disorder

Mahajan, V. R., Elvig, S. K., Vendruscolo, L. F., Koob, G. F., Darcey, V. L., King, M. T., Kranzler, H. R., Volkow, N. D., & Wiers, C. E. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.781668 · Cited by 34

Resistant Maltodextrin and Metabolic Syndrome: A Review

Astina, J., & Sapwarobol, S. (2018) · Journal of the American College of Nutrition · doi:10.1080/07315724.2018.1523028 · Cited by 33

Gene variants in Eating Disorders. Focus on Anorexia Nervosa Bulimia Nervosa and Binge-eating Disorder

Donato, K., Ceccarini, M. R., Dhuli, K., Bonetti, G., Medori, M. C., Marceddu, G., Precone, V., Xhufi, S., Bushati, M., Bozo, D., et al. (2022) · Journal of preventive medicine and hygiene · doi:10.15167/2421-4248/jpmh2022.63.2s3.2772 · Cited by 32

Duodenal and ileal glucose infusions differentially alter gastrointestinal peptides, appetite response, and food intake: a tube feeding study

Poppitt, S. D., Shin, H. S., McGill, A., Budgett, S. C., Lo, K., Pahl, M. C., Duxfield, J., Lane, M. R., & Ingram, J. R. (2017) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.117.157248 · Cited by 32

Effects of carbohydrate restriction on postprandial glucose metabolism, β-cell function, gut hormone secretion, and satiety in patients with Type 2 diabetes

Skytte, M. J., Samkani, A., Astrup, A. V., Frystyk, J., Rehfeld, J. F., Holst, J. J., Madsbad, S., Burling, K., Fenger, M., Thomsen, M. N., et al. (2020) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00165.2020 · Cited by 43

Changes in levels of peripheral hormones controlling appetite are inconsistent with hyperphagia in leptin-deficient subjects

Saeed, S., Bech, P., Hafeez, T., Alam, R., Falchi, M., Ghatei, M. A., Bloom, S. R., Arslan, M., & Froguel, P. (2013) · Endocrine · doi:10.1007/s12020-013-0009-9 · Cited by 32

Anorexigenic postprandial responses of PYY and GLP1 to slow ice cream consumption: preservation in obese adolescents, but not in obese adults

Rigamonti, A. E., Agosti, F., Compri, E., Giunta, M., Marazzi, N., Müller, E. E., Cella, S. G., & Sartório, A. (2012) · European Journal of Endocrinology · doi:10.1530/eje-12-0867 · Cited by 32

The role of polydextrose in body weight control and glucose regulation

Canfora, E. E., & Blaak, E. E. (2015) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000184 · Cited by 32

Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

Albrechtsen, N. J. W., Kuhre, R. E., Deacon, C. F., & Holst, J. J. (2013) · Expert Review of Endocrinology & Metabolism · doi:10.1586/17446651.2014.862152 · Cited by 32

Multisensory influence on eating behavior: Hedonic consumption

de Eguilaz, M. H. R., Aldabe, B. M. D. M., Almiron‐Roig, E., Pérez-Díez, S., San-Cristóbal, R., Navas‐Carretero, S., & Martínez, J. A. (2018) · Endocrinología Diabetes y Nutrición (English ed ) · doi:10.1016/j.endien.2018.03.003 · Cited by 32

Precision nutrition in the context of bariatric surgery

Aguas‐Ayesa, M., Yárnoz‐Esquíroz, P., Olazarán, L., Gómez‐Ambrosi, J., & Frühbeck, G. (2023) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-023-09794-5 · Cited by 31

Efficacy and Safety of Sipjeondaebo‐Tang for Anorexia in Patients with Cancer: A Pilot, Randomized, Double‐Blind, Placebo‐Controlled Trial

Cheon, C., Yoo, J., Yoo, H., Cho, C.-K., Kang, S., Kim, M., Jang, B.-H., Shin, Y. C., & Ko, S. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/8780325 · Cited by 31

Unraveling the Connections: Eating Issues, Microbiome, and Gastrointestinal Symptoms in Autism Spectrum Disorder

Tomaszek, N., Urbaniak, A. D., Bałdyga, D., Chwesiuk, K., Modzelewski, S., & Waszkiewicz, N. (2025) · Nutrients · doi:10.3390/nu17030486 · Cited by 30

Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity

Lear, S., Pflimlin, E., Zhou, Z., Huang, D., Weng, S., Nguyen-Tran, V. T. B., Joseph, S. B., Roller, S. G., Peterson, S., Li, J., et al. (2020) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.0c00740 · Cited by 29

Amelioration of obesity in high-fat diet-fed mice by chestnut starch modified by amylosucrase from Deinococcus geothermalis

Lee, E., Lee, B., Shin, D., Lim, M.-Y., Chung, W., Park, C., Baik, M., Nam, Y., & Seo, D. (2017) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2017.09.019 · Cited by 31

The role of the autonomic nervous system in polycystic ovary syndrome

Yu, Y., Chen, T., Zheng, Z., Jia, F., Liao, Y., Ren, Y., Liu, X., & Liu, Y. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1295061 · Cited by 32

Circadian clock-gastrointestinal peptide interaction in peripheral tissues and the brain

Landgraf, D., Neumann, A.-M., & Oster, H. (2017) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2017.10.007 · Cited by 26

The Effects of Kisspeptin on Brain Response to Food Images and Psychometric Parameters of Appetite in Healthy Men

Yang, L. Y., Demetriou, L., Wall, M. B., Mills, E., Wing, V. C., Thurston, L., Schaufelberger, C. N., Owen, B. M., Abbara, A., Rabiner, E. A., et al. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa746 · Cited by 26

Short-Chain Fatty Acid Production and Functional Aspects on Host Metabolism

Tungland, B. C. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-814649-1.00002-8 · Cited by 29

Gut microbiota and type 2 diabetes mellitus: a focus on the gut-brain axis

Pan, Y., Bu, T., Deng, X., Jia, J., & Yuan, G. (2024) · Endocrine · doi:10.1007/s12020-023-03640-z · Cited by 28

Glucose-lowering therapies in type 2 diabetes: Opportunities and challenges for peptides

Bailey, C. J. (2018) · Peptides · doi:10.1016/j.peptides.2017.11.012 · Cited by 23

Half-Life Extending Modifications of Peptide YY3–36 Direct Receptor-Mediated Internalization

Bech, E. M., Kaiser, A., Bellmann‐Sickert, K., Bohr, S. S.-R., Sørensen, K. K., Elster, L., Hatzakis, N. S., Pedersen, S. L., Beck‐Sickinger, A. G., & Jensen, K. J. (2019) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.9b00554 · Cited by 23

Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

Kamakura, R., Raza, G. S., Prasannan, A., Walkowiak, J., & Herzig, K. (2020) · Peptides · doi:10.1016/j.peptides.2020.170419 · Cited by 23

Identification and Validation of Nutrient State-Dependent Serum Protein Mediators of Human CD4+ T Cell Responsiveness

Han, K., Singh, K., Rodman, M. J., Hassanzadeh, S., Baumer, Y., Huffstutler, R. D., Chen, J., Candia, J., Cheung, F., Stagliano, K. E., et al. (2021) · Nutrients · doi:10.3390/nu13051492 · Cited by 22

Orthostatic intolerance and autonomic dysfunction following bariatric surgery: A retrospective study and review of the literature

Ponnusamy, V., Owens, A. P., Purkayastha, S., Iodice, V., & Mathias, C. J. (2016) · Autonomic Neuroscience · doi:10.1016/j.autneu.2016.05.003 · Cited by 23

Effect of Short Chain Fatty Acids on Age-Related Disorders

Fernandes, M. F., de Oliveira, S., Portovedo, M., Rodrigues, P. B., & Vinolo, M. A. R. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-42667-5_4 · Cited by 22

Synthetic small molecule GLP-1 secretagogues prepared by means of a three-component indole annulation strategy

Chepurny, O. G., Leech, C. A., Tomanik, M., DiPoto, M. C., Li, H., Han, X., Meng, Q., Cooney, R. N., Wu, J. Y.-C., & Holz, G. G. (2016) · Scientific Reports · doi:10.1038/srep28934 · Cited by 21

Adjustment of Whey:Casein Ratio from 20:80 to 60:40 in Milk Formulation Affects Food Intake and Brainstem and Hypothalamic Neuronal Activation and Gene Expression in Laboratory Mice

Wood, E. L., Christian, D. G., Arafat, M., McColl, L. K., Prosser, C. G., Carpenter, E. A., Levine, A. S., Klockars, A., & Olszewski, P. K. (2021) · Foods · doi:10.3390/foods10030658 · Cited by 21

The impacts and mechanisms of dietary proteins on glucose homeostasis and food intake: a pivotal role of gut hormones

Zhang, M., Zhu, L., Wu, G., Zhang, H., Wang, X., & Qi, X. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2023.2256400 · Cited by 21

The neurotoxicity of acrylamide in ultra-processed foods: interventions of polysaccharides through the microbiota–gut–brain axis

Cai, C., Song, Z., Xu, X., Yang, X., Wei, S., Chen, F., Dong, X., Zhang, X., & Zhu, Y. (2024) · Food & Function · doi:10.1039/d4fo03002h · Cited by 20

Wx/ae Double-Mutant Brown Rice Prevents the Rise in Plasma Lipid and Glucose Levels in Mice

Matsumoto, K., MAEKAWA, M., Nakaya, M., Takemitsu, H., Satoh, H., & Kitamura, S. (2012) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.120501 · Cited by 18

Nonclassical Islet Peptides: Pancreatic and Extrapancreatic Actions

English, A. R., & Irwin, N. (2019) · Clinical Medicine Insights Endocrinology and Diabetes · doi:10.1177/1179551419888871 · Cited by 19

Dietary corn resistant starch regulates intestinal morphology and barrier functions by activating the Notch signaling pathway of broilers

Zhang, Y., Liu, Y., Li, J., Xing, T., Jiang, Y., Zhang, L., & Gao, F. (2020) · Asian-Australasian Journal of Animal Sciences · doi:10.5713/ajas.19.0967 · Cited by 19

Innovative Applications of Pectin in Lipid Management: Mechanisms, Modifications, Synergies, Nanocarrier Systems, and Safety Considerations

Song, H., Chen, F., Cao, Y., Wang, F., Wang, L., Xiong, L. H., & Shen, X. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c06586 · Cited by 19

Effect of branched-chain amino acids on food intake and indicators of hunger and satiety- a narrative summary

Lueders, B., Kanney, B. C., Krone, M. J., Gannon, N. P., & Vaughan, R. A. (2022) · Human Nutrition & Metabolism · doi:10.1016/j.hnm.2022.200168 · Cited by 18

The Effect of Exercise Intensity on Gastric Emptying Rate, Appetite and Gut Derived Hormone Responses after Consuming a Standardised Semi-Solid Meal in Healthy Males

Mattin, L. R., Yau, A. M. W., McIver, V. J., James, L. J., & Evans, G. H. (2018) · Nutrients · doi:10.3390/nu10060787 · Cited by 18

A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans

Sun, E. W. L., Iepsen, E. W., Pezos, N., Lumsden, A. L., Martin, A. M., Schober, G., Isaacs, N. J., Rayner, C. K., Nguyen, N. Q., de Fontgalland, D., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.04.014 · Cited by 18

Liraglutide for the Treatment of Weight Regain After Bariatric Surgery: A Systematic Review and Meta-analysis

de Moraes, F. C. A., Morbach, V., Sano, V. K. T., Fernandes, L. R., Kreuz, M., & Kelly, F. A. (2024) · Obesity Surgery · doi:10.1007/s11695-024-07384-1 · Cited by 19

Effect of PANDER in βTC6-cell lipoapoptosis and the protective role of exendin-4

Xiang, J.-N., Chen, D., & Yang, L. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.04.065 · Cited by 17

Mixed Meal and Intravenous L-Arginine Tests Both Stimulate Incretin Release Across Glucose Tolerance in Man: Lack of Correlation with β Cell Function

Ruetten, H., Gebauer, M., Raymond, R. H., Calle, R. A., Cobelli, C., Ghosh, A., Robertson, R. P., Shankar, S. S., Staten, M. A., Stefanovski, D., et al. (2018) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2018.0022 · Cited by 17

Variability of Length of Small Intestine in Indian Population and Its Correlation with Type 2 Diabetes Mellitus and Obesity

Purandare, A., Phalgune, D. S., & Shah, S. S. (2019) · Obesity Surgery · doi:10.1007/s11695-019-03921-5 · Cited by 17

Rational Development of Stable PYY3–36 Peptide Y2 Receptor Agonists

Poulsen, C., Pedersen, M. Ø., Wahlund, P., Sjölander, A., Thomsen, J. K., Conde‐Frieboes, K. W., Paulsson, J. F., Wulff, B. S., & Østergaard, S. (2021) · Pharmaceutical Research · doi:10.1007/s11095-021-03077-x · Cited by 17

Extrusion cooking of cassava-soy flour with 200 g/kg wheat bran promotes slower oral processing during consumption of the instant porridge and higher derived satiety

Oladiran, D. A., Emmambux, M. N., & de Kock, H. L. (2018) · LWT · doi:10.1016/j.lwt.2018.07.068 · Cited by 16

Difficulties in Translating Appetite Sensations Effect of Turmeric-Based Beverage When Given Prior to Isoenergetic Medium- or High-Fat Meals in Healthy Subjects

Zanzer, Y. C., Batista, Â. G., Dougkas, A., Tovar, J., Granfeldt, Y. E., & Östman, E. M. (2019) · Nutrients · doi:10.3390/nu11040736 · Cited by 16

The combined administration of EGCG and caffeine induces not only suppression of fat accumulation but also anorexigenic action in mice

Liu, L., & Sayama, K. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.05.030 · Cited by 15

Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus

Dascălu, A. M., Stoian, A. P., Popa‐Cherecheanu, A., Şerban, D., Costea, D. O., Tudosie, M. S., Stana, D., Tănăsescu, D., Sabău, A. D., Gangura, G. A., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10163736 · Cited by 18

Satiety, glycemic profiles, total antioxidant capacity, and postprandial glycemic responses to different sugars in healthy Malaysian adults

Azlan, A., Ebadi, S., Yusof, B. N. M., Othman, N. M. H., Kannar, D., Sultana, S., & Mahmood, Z. (2021) · Nutrition · doi:10.1016/j.nut.2021.111551 · Cited by 15

GPR84 in physiology—Many functions in many tissues

Aktar, R., Rondinelli, S., & Peiris, M. (2023) · British Journal of Pharmacology · doi:10.1111/bph.16206 · Cited by 17

Crosstalk between adipose tissue and the microbiota-gut-brain axis in metabolic diseases

Yu, Z.-W., Wang, Y., Yu, Z. H., Lu, M., & Xu, B. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.68786 · Cited by 15

Post-prandial anorexigenic gut peptide, appetite and glucometabolic responses at different eating rates in obese patients undergoing laparoscopic sleeve gastrectomy

Rigamonti, A. E., Bini, S., Rocco, M. C., Giardini, V., Massimini, D., Crippa, M. G., Saluzzi, A., Casati, M., Marazzi, N., Perotti, M., et al. (2016) · Endocrine · doi:10.1007/s12020-016-0933-6 · Cited by 14

Pituitary disease in pediatric brain tumor survivors

Howell, J. C., & Rose, S. R. (2019) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2019.1620599 · Cited by 14

GI inflammation Increases Sodium-Glucose Cotransporter Sglt1

Park, J., Lee, I., Kim, K., Kim, Y., An, E.-J., & Jang, H.-J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102537 · Cited by 14

Gastrointestinal Peptides During Chronic Gastric Electrical Stimulation in Patients With Intractable Vomiting

Méleine, M., Melchior, C., Prinz, P., Penfornis, A., Coffin, B., Stengel, A., Ducrotte, P. R., & Gourcerol, G. (2017) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12645 · Cited by 13

Inorganic mesoporous particles for controlled α-linolenic acid delivery to stimulate GLP-1 secretion in vitro

Kamakura, R., Kovalainen, M., Riikonen, J., Nissinen, T., Raza, G. S., Walkowiak, J., Lehto, V., & Herzig, K. (2019) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2019.09.009 · Cited by 13

Gut sensing of dietary amino acids, peptides and proteins, and feed-intake regulation in pigs

Muller, M., Ryoo, M. C.-K., & Roura, E. (2021) · Animal Production Science · doi:10.1071/an21185 · Cited by 13

Yacon-based product improves intestinal hypertrophy and modulates the production of glucagon-like peptide-1 in postmenopausal experimental model

Martins, J. D. F. L., Silva, T. G. D. S. E., Paula, H. A. D. A., Rafael, V. D. C., Sartori, S. S. R., & Ferreira, C. L. D. L. F. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120245 · Cited by 13

The Microbiota-gut-brain axis: Clinical Applications In Obesity and Type 2 Diabetes

Moser, B., Milligan, M. A., & Dao, M. C. (2022) · Revista de investigaci�n Cl�nica · doi:10.24875/ric.22000197 · Cited by 14

Type 2 Diabetes Control in a Nonobese Rat Model Using Sleeve Gastrectomy with Duodenal–Jejunal Bypass (SGDJB)

Sun, D., Liu, S., Zhang, G., Chen, W., Yan, Z., & Hu, S. (2012) · Obesity Surgery · doi:10.1007/s11695-012-0744-7 · Cited by 13

A Simple Food-Diverting Operation for Type 2 Diabetes Treatment. Preliminary Results in Humans with BMI 28–32 kg/m2

Melissas, J., ErenTaskin, H., Peirasmakis, D., Dimitriadis, E., Papadakis, M., Zengin, S. Ü., Yumuk, V., & Taşkın, M. (2016) · Obesity Surgery · doi:10.1007/s11695-016-2251-8 · Cited by 15

Photoperiodic changes in adiposity increase sensitivity of female Siberian hamsters to systemic VGF derived peptide TLQP-21

Lisci, C., Lewis, J. E., Daniel, Z. C. T. R., Stevenson, T. J., Monnier, C., Marshall, H. J., Fowler, M. J., Ebling, F. J. P., Ferri, G., Cocco, C., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0221517 · Cited by 13

Interrupting Prolonged Sitting with Intermittent Walking Increases Postprandial Gut Hormone Responses

Chen, Y., Walhin, J., Hengist, A., Gonzalez, J. T., Betts, J. A., & Thompson, D. (2022) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002903 · Cited by 13

Ghrelin, acylated ghrelin, leptin and PYY-3 levels in hyperemesis gravidarum

Albayrak, M., Karatas, A., Demiraran, Y., Erman, H., Topuz, S., Bıyık, İ., Uzun, H., & Erkan, M. (2013) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2013.766699 · Cited by 13

The role of bariatric surgery in the treatment of type 2 diabetes mellitus

Leong, W. B., & Taheri, S. (2012) · The Journal of the Royal College of Physicians of Edinburgh · doi:10.4997/jrcpe.2012.301 · Cited by 14

Peptide YY in Type 2 Diabetes: A Complementary Gut Hormone with Therapeutic Potential Beyond GLP-1

Nguyen, N. T. H., & Park, J. (2025) · Nutrients · doi:10.3390/nu17213468 · Cited by 12

Hypoabsorption in Bariatric Surgery: Is the Benefit Worth the Risk?

Abedalqader, T., Jawhar, N., Gajjar, A., Portela, R. C., Perrotta, G., Ghazal, N. E., Laplante, S. J., & Ghanem, O. M. (2025) · Medicina · doi:10.3390/medicina61030398 · Cited by 13

Fibres as functional foods and the effects on gut hormones: The example of β-glucans in a single arm pilot study

Baldassano, S., Accardi, G., Aiello, A., Buscemi, S., Miceli, G. D., Galimberti, D., Candore, G., Ruisi, P., Caruso, C., & Vasto, S. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.05.059 · Cited by 12

Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats

Johnson, M. L., Saffrey, M. J., & Taylor, V. (2017) · Peptides · doi:10.1016/j.peptides.2017.02.010 · Cited by 12

Investigation of Newly Diagnosed Drug‐Naive Patients with Systemic Autoimmune Diseases Revealed the Cleaved Peptide Tyrosine Tyrosine (PYY 3‐36) as a Specific Plasma Biomarker of Rheumatoid Arthritis

Balog, J. Á., Kemény, Á., Puskás, L. G., Burcsár, S., Balog, A., & Szebeni, G. J. (2021) · Mediators of Inflammation · doi:10.1155/2021/5523582 · Cited by 12

Does the ileal brake mechanism contribute to sustained weight loss after bariatric surgery?

Barreto, S. G., Soenen, S., Chisholm, J. A., Chapman, I. M., & Kow, L. (2017) · ANZ Journal of Surgery · doi:10.1111/ans.14062 · Cited by 13

Effects of multiple cycles of weight loss and regain on the body weight regulatory system in rats

Rosenbaum, J. L., Frayo, R. S., Melhorn, S. J., Cummings, D. E., & Schur, E. A. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00110.2019 · Cited by 13

Plasma dipeptidyl peptidase IV activity and measures of body composition in apparently healthy people

Neidert, L. E., Wainright, K. S., Zheng, C., Babu, J. R., & Kluess, H. A. (2016) · Heliyon · doi:10.1016/j.heliyon.2016.e00097 · Cited by 11

The serine protease, dipeptidyl peptidase IV as a myokine: dietary protein and exercise mimetics as a stimulus for transcription and release

Neidert, L. E., Mobley, C. B., Kephart, W. C., Roberts, M. D., & Kluess, H. A. (2016) · Physiological Reports · doi:10.14814/phy2.12827 · Cited by 11

Relationship between peptide YY, cholecystokinin and fermentation products in fasted, re-fed and ad libitum fed broiler chickens

Melo‐Durán, D., González‐Ortiz, G., Solà‐Oriol, D., Martínez-Mora, M., Pérez, J. F., & Bedford, M. R. (2018) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2018.11.007 · Cited by 11

Novel approaches to anti-obesity drug discovery with gut hormones over the past 10 years

Rose, F., Bloom, S. R., & Tan, T. (2019) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2019.1646243 · Cited by 11

Intestinal Dysbiosis and Development of Cardiometabolic Disorders in Childhood Cancer Survivors: A Critical Review

Morel, S., DELVIN, E. E., Marcil, V., & Levy, E. H. (2020) · Antioxidants and Redox Signaling · doi:10.1089/ars.2020.8102 · Cited by 11

Generation and characterisation of C-terminally stabilised PYY molecules with potential in vivo NPYR2 activity

Lafferty, R. A., Tanday, N., Flatt, P. R., & Irwin, N. (2020) · Metabolism · doi:10.1016/j.metabol.2020.154339 · Cited by 11

Unexpectedly increased anorexigenic postprandial responses of PYY and GLP ‐1 to fast ice cream consumption in adult patients with P rader‐ W illi syndrome

Rigamonti, A. E., Bini, S., Grugni, G., Agosti, F., Col, A. D., Mallone, M., Cella, S. G., & Sartório, A. (2013) · Clinical Endocrinology · doi:10.1111/cen.12395 · Cited by 11

Vertical sleeve gastrectomy improves liver and hypothalamic functions in obese mice

Li, P.-X., Rao, Z., Laing, B. T., Bunner, W., Landry, T., Prete, A., Yuan, Y., Zhang, Z., & Hu, H. (2019) · Journal of Endocrinology · doi:10.1530/joe-18-0658 · Cited by 11

Synbiotic as an adjunctive agent can be useful in the management of hyperglycemia in adults: An umbrella review and meta-research of meta-analysis studies

Musazadeh, V., Faghfouri, A. H., Kavyani, Z., & Dehghan, P. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105355 · Cited by 10

Anti-Obesity Mechanisms of Plant and Fungal Polysaccharides: The Impact of Structural Diversity

Fang, G., Li, B., Zhu, L., Chen, L., Xiao, J., & Chen, J. (2025) · Biomolecules · doi:10.3390/biom15081140 · Cited by 9

Diets enriched with finely ground wheat bran alter digesta passage rate and composition of the gut microbiome in sows

Wang, Z., Wang, W., Xu, S., Ding, J., Zeng, X., Hu, L., & Wang, F. (2022) · Animal nutrition · doi:10.1016/j.aninu.2022.08.012 · Cited by 10

Effect of the ingestion of the palm oil and glutamine in serum levels of GLP-1, PYY and glycemia in diabetes mellitus type 2 patients submitted to metabolic surgery

Takeuti, T. D., Terra, G. A., da Silva, A. A., Júnior, J. A. T., da SILVA, L. M., & Crema, E. (2014) · ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) · doi:10.1590/s0102-6720201400s100013 · Cited by 9

Genes Downregulated in Endometriosis Are Located Near the Known Imprinting Genes

Kobayashi, H., Higashiura, Y., Koike, N., Akasaka, J., Uekuri, C., Iwai, K., Niiro, E., Morioka, S., & Yamada, Y. (2014) · Reproductive Sciences · doi:10.1177/1933719114526473 · Cited by 10

The Intricate Relationship between Circadian Rhythms and Gastrointestinal Peptides in Obesity

Ribeiro, F. M., Arnaldo, L., P. Milhomem, L., S. Aguiar, S., & Franco, O. L. (2025) · Peptides · doi:10.1016/j.peptides.2025.171356 · Cited by 9

Smart control lipid-based nanocarriers for fine-tuning gut hormone secretion

Xu, Y., Michalowski, C. B., Koehler, J. A., Darwish, T., Guccio, N., Alcaino, C., Domingues, I., Zhang, W., Marotti, V., Hul, M. V., et al. (2024) · Science Advances · doi:10.1126/sciadv.adq9909 · Cited by 9

Effects of varying the inter-meal interval on relationships between antral area, gut hormones and energy intake following a nutrient drink in healthy lean humans

Little, T. J., Luscombe‐Marsh, N. D., Gentilcore, D., Brook, E. J., & Feinle‐Bisset, C. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.05.040 · Cited by 9

Postprandial effects of a polyphenolic grape extract (PGE) supplement on appetite and food intake: a randomised dose-comparison trial

Shin, H.-S., Kindleysides, S., Yip, W. C. Y., Budgett, S. C., Ingram, J. R., & Poppitt, S. D. (2015) · Nutrition Journal · doi:10.1186/s12937-015-0085-1 · Cited by 9

review Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity

Silva, A. D., & Bloom, S. R. (2013)

Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass

le Roux, C. W., Welbourn, R., Werling, M., Osborne, A., Kokkinos, A., Laurenius, A., Lönroth, H., Fändriks, L., Ghatei, M. A., Bloom, S. R., et al. (2007) · Annals of Surgery · doi:10.1097/sla.0b013e3180caa3e3 · Cited by 741

A medical bypass. Can the manipulation of gut hormone levels replicate the favourable effects on energy and glucose homeostasis seen following gastric bypass surgery?

Troke, R. (2016) · doi:10.25560/47922

Gut Hormones as Peripheral Anti Obesity Targets

Small, C. J., & Bloom, S. R. (2004) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1568007043336950 · Cited by 50

Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

Svane, M. S., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Nielsen, S., Kristiansen, V. B., Toräng, S., Wewer Albrechtsen, N. J., Rehfeld, J. F., Hartmann, B., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.121 · Cited by 185