2D and 3D Cell Cultures - a Comparison of Different Types of Cancer Cell Cultures

Matrix elasticity directs stem cell lineage specification

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The third dimension bridges the gap between cell culture and live tissue

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Exploring and Engineering the Cell Surface Interface

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Capturing complex 3D tissue physiology in vitro

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Geometric cues for directing the differentiation of mesenchymal stem cells

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Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

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Modeling Tissue Morphogenesis and Cancer in 3D

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Spheroid-based drug screen: Considerations and practical approach

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Socializing with the Neighbors

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Matrigel: Basement membrane matrix with biological activity

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Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

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Three-dimensional cell culture: the missing link in drug discovery

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Spherical Cancer Models in Tumor Biology

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Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer

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Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

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Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture

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Three-Dimensional Cell Culture Matrices: State of the Art

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Modelling glandular epithelial cancers in three-dimensional cultures

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Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

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Engineering tumors with 3D scaffolds

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β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

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Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds

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Tumor heterogeneity.

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The outgrowth of the nerve fiber as a mode of protoplasmic movement

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Co-culture systems and technologies: taking synthetic biology to the next level

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Three-dimensional tissue culture models in cancer biology

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Observations on the living developing nerve fiber

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Gene expression perturbation in vitro—A growing case for three-dimensional (3D) culture systems

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3D Cell Culture: A Review of Current Approaches and Techniques

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Tissue architecture: the ultimate regulator of breast epithelial function

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Biomaterials for stem cell differentiation

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Three‐dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo

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Hepatocyte behavior within three-dimensional porous alginate scaffolds

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3D cell culture opens new dimensions in cell-based assays

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Directing cell motions on micropatterned ratchets

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Three-dimensional culture of melanoma cells profoundly affects gene expression profile: A high density oligonucleotide array study

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Functional differentiation of hepatocyte-like spheroid structures from putative liver progenitor cells in three-dimensional peptide scaffolds

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An Integrated Computational/Experimental Model of Tumor Invasion

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A biomimetic hydrogel based on methacrylated dextran-graft-lysine and gelatin for 3D smooth muscle cell culture

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Patterning network structure to spatially control cellular remodeling and stem cell fate within 3-dimensional hydrogels

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Coculture of Human Mesenchymal Stem Cells and Articular Chondrocytes Reduces Hypertrophy and Enhances Functional Properties of Engineered Cartilage

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Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?

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Three-Dimensional (3D) Tumor Spheroid Invasion Assay

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Evaluation of Nanostructured Composite Collagen–Chitosan Matrices for Tissue Engineering

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Functional behavior of primary rat liver cells in a three-dimensional perfused microarray bioreactor

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Potential for Control of Signaling Pathways via Cell Size and Shape

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Advances in tissue engineering through stem cell-based co-culture

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Beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

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Enhanced Tumor Growth of Both Primary and Established Human and Murine Tumor Cells in Athymic Mice After Coinjection With Matrigel

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Three-Dimensional Cell Growth Confers Radioresistance by Chromatin Density Modification

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Models for prevention and treatment of cancer: Problems vs promises

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Nonadhesive Culture System as a Model of Rapid Sphere Formation with Cancer Stem Cell Properties

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Chondrogenic Differentiation of Human Embryonic Stem Cells: The Effect of the Micro-Environment

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Upregulation of the Viability of Nucleus Pulposus Cells by Bone Marrow-Derived Stromal Cells

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Co-culture in cartilage tissue engineering

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3D Models of Epithelial-Mesenchymal Transition in Breast Cancer Metastasis: High-Throughput Screening Assay Development, Validation, and Pilot Screen

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MicroRNA‐200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells

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New depths in cell behaviour: reactions of cells to nanotopography.

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Rapid ex vivo expansion of human umbilical cord hematopoietic progenitors using a novel culture system

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Micropatterns of Matrigel for three-dimensional epithelial cultures

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Silk as an innovative biomaterial for cancer therapy

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Implantable Three-Dimensional Salivary Spheroid Assemblies Demonstrate Fluid and Protein Secretory Responses to Neurotransmitters

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Cell Type and Culture Condition–Dependent Alternative Splicing in Human Breast Cancer Cells Revealed by Splicing-Sensitive Microarrays

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In vivo evaluation of hsp27 as an inhibitor of actin polymerization: Hsp27 limits actin stress fiber and focal adhesion formation after heat shock

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ADF/cofilin family proteins control formation of oriented actin-filament bundles in the cell body to trigger fibroblast polarization

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Lumen formation in three‐dimensional cultures of salivary acinar cells

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3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226

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The successes and limitations of preclinical studies in predicting the pharmacodynamics and safety of cell‐surface‐targeted biological agents in patients

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Orosphere assay: A method for propagation of head and neck cancer stem cells

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In vitro cardiomyogenic potential of human amniotic fluid stem cells

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A novel in vivo model for evaluating functional restoration of a tissue-engineered salivary gland

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Three-dimensional type I collagen gel system containing MG-63 osteoblasts-like cells as a model for studying local bone reaction caused by metastatic cancer cells.

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Dual targeting of EGFR and focal adhesion kinase in 3D grown HNSCC cell cultures

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Three-Dimensional (3D) Tumor Spheroid Invasion Assay

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Endothelial derived factors inhibit anoikis of head and neck cancer stem cells

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Three-dimensional co-culture facilitates the differentiation of embryonic stem cells into mature cardiomyocytes

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The Effect of Primary Cancer Cell Culture Models on the Results of Drug Chemosensitivity Assays: The Application of Perfusion Microbioreactor System as Cell Culture Vessel

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Enhanced chemoresistance of squamous carcinoma cells grown in 3D cryogenic electrospun scaffolds

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Evolution of cell-based reagent provision

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Three-dimensional culture promotes reconstitution of the tumor-specific hypoxic microenvironment under TGFβ stimulation

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Isolation of Mammary Epithelial Cells from Three-dimensional Mixed-cell Spheroid Co-culture

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Endothelial invasive response in a co-culture model with physically-induced osteodifferentiation

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Introduction to Animal Cell Culture

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Microprecision Delivery of Oligonucleotides in a 3D Tissue Model and Its Characterization Using Optical Imaging

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Isolation of Mammary Epithelial Cells from Three-dimensional Mixed-cell Spheroid Co-culture

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Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

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Is it time to start transitioning from 2D to 3D cell culture?

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Spheroids as a Type of Three-Dimensional Cell Cultures—Examples of Methods of Preparation and the Most Important Application

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3D Cell Culture Models as Recapitulators of the Tumor Microenvironment for the Screening of Anti-Cancer Drugs

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Could 3D models of cancer enhance drug screening?

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Organ-on-a-chip meets artificial intelligence in drug evaluation

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Three-Dimensional Cell Culture at the Frontiers of in Vitro Cancer Research: Present Perspectives

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Why 3D in vitro cancer models are the future of cancer research?

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Life is Three Dimensional—As In Vitro Cancer Cultures Should Be

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Current Perspectives on 2D and 3D Cell Culture Models in Cancer Research: Molecular Determinants of Tumor Biology and Therapeutic Response

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2D and 3D cell culture: Getting close to mimicking the tumor microenvironment in vitro

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