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Enhanced recovery after surgery (ERAS) protocols: Time to change practice?
Open accessAbstract
Radical cystectomy with pelvic lymph node dissection remains the standard treatment for patients with muscle invasive bladder cancer. Despite improvements in surgical technique, anesthesia and perioperative care, radical cystectomy is still associated with greater morbidity and prolonged in-patient stay after surgery than other urological procedures. Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery after surgical procedures by maintaining preoperative organ function and reducing the profound stress response following surgery. The key elements of ERAS protocols include preoperative counselling, optimization of nutrition, standardized analgesic and anesthetic regimens and early mobilization. Despite the significant body of evidence indicating that ERAS protocols lead to improved outcomes, they challenge traditional surgical doctrine, and as a result their implementation has been slow.The present article discusses particular aspects of ERAS protocols which represent fundamental shifts in surgical practice, including perioperative nutrition, management of postoperative ileus and the use of mechanical bowel preparation.
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Cites
Intensive insulin therapy in critically ill patients.
Van den Berghe, G., Wouters, P., Weekers, F., Verwaest, C., Bruyninckx, F., Schetz, M., Vlasselaers, D., Ferdinande, P., Lauwers, P., & Bouillon, R. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011300 · Cited by 9,977
Multimodal approach to control postoperative pathophysiology and rehabilitation
Kehlet, H. (1997) · British Journal of Anaesthesia · doi:10.1093/bja/78.5.606 · Cited by 2,827
The stress response to trauma and surgery
Desborough, J. P. (2000) · British Journal of Anaesthesia · doi:10.1093/bja/85.1.109 · Cited by 2,296
Multimodal strategies to improve surgical outcome
Kehlet, H., & Wilmore, D. W. (2002) · The American Journal of Surgery · doi:10.1016/s0002-9610(02)00866-8 · Cited by 1,863
Fearon, K. C. H., Ljungqvist, O., Von Meyenfeldt, M., Revhaug, A., Dejong, C. H. C., Lassen, K., Nygren, J., Hausel, J., Soop, M., Andersen, J., et al. (2005) · Clinical Nutrition · doi:10.1016/j.clnu.2005.02.002 · Cited by 1,693
Anaesthesia, surgery, and challenges in postoperative recovery
Kehlet, H., & Dahl, J. B. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14966-5 · Cited by 1,446
Shabsigh, A., Korets, R., Vora, K. C., Brooks, C. M., Cronin, A. M., Savage, C., Raj, G., Bochner, B. H., Dalbagni, G., Herr, H. W., et al. (2009) · European Urology · doi:10.1016/j.eururo.2008.07.031 · Cited by 1,400
ESPEN Guidelines on Enteral Nutrition: Surgery including Organ Transplantation
Weimann, A., Braga, M., Harsanyi, L., Laviano, A., Ljungqvist, O., Soeters, P., Jauch, K. W., Kemen, M., Hiesmayr, J. M., Horbach, T., et al. (2006) · Clinical Nutrition · doi:10.1016/j.clnu.2006.01.015 · Cited by 1,119
Lassen, K. (2009) · Archives of Surgery · doi:10.1001/archsurg.2009.170 · Cited by 1,096
Lewis, S. J., Egger, M., Sylvester, P. A., & Thomas, S. (2001) · BMJ · doi:10.1136/bmj.323.7316.773 · Cited by 858
Management of patients in fast track surgery
Wilmore, D. W., & Kehlet, H. (2001) · BMJ · doi:10.1136/bmj.322.7284.473 · Cited by 796
Preoperative fasting for adults to prevent perioperative complications
Brady, M. C., Kinn, S., Stuart, P., & Ness, V. (2003) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004423 · Cited by 694
Systematic review of enhanced recovery programmes in colonic surgery
Fast Track Multimodal Management Versus Standard Care (LAFA) study group, Enhanced Recovery After Surgery (ERAS) group, Wind, J., Polle, S. W., Fung Kon Jin, P. H. P., Dejong, C. H. C., von Meyenfeldt, M. F., Ubbink, D. T., Gouma, D. J., & Bemelman, W. A. (2006) · British Journal of Surgery · doi:10.1002/bjs.5384 · Cited by 681
Hospital stay of 2 days after open sigmoidectomy with a multimodal rehabilitation programme
Kehlet, H., & Mogensen, T. (1999) · Journal of British Surgery · doi:10.1046/j.1365-2168.1999.01023.x · Cited by 577
Insulin resistance: a marker of surgical stress
Thorell, A., Nygren, J., & Ljungqvist, O. (1999) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/00075197-199901000-00012 · Cited by 552
A Carbohydrate-Rich Drink Reduces Preoperative Discomfort in Elective Surgery Patients
Hausel, J., Nygren, J., Lagerkranser, M., Hellström, P. M., Hammarqvist, F., Almström, C., Lindh, A., Thorell, A., & Ljungqvist, O. (2001) · Anesthesia & Analgesia · doi:10.1097/00000539-200111000-00063 · Cited by 536
A protocol is not enough to implement an enhanced recovery programme for colorectal resection
Maessen, J., Dejong, C. H. C., Hausel, J., Nygren, J., Lassen, K., Andersen, J., Kessels, A. G. H., Revhaug, A., Kehlet, H., Ljungqvist, O., et al. (2007) · British Journal of Surgery · doi:10.1002/bjs.5468 · Cited by 533
Mechanisms and Treatment of Postoperative Ileus
Luckey, A. (2003) · Archives of Surgery · doi:10.1001/archsurg.138.2.206 · Cited by 478
Intensive Insulin Therapy in Critically Ill Patients
(2002) · New England Journal of Medicine · doi:10.1056/nejm200205163462016 · Cited by 454
Lewis, S. J., Andersen, H. K., & Thomas, S. (2009) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-008-0592-x · Cited by 453
Radical Cystectomy for Carcinoma of the Bladder: Critical Evaluation of the Results in 1,026 Cases
Ghoneim, M. A., El-Mekresh, M. M., El-Baz, M. A., Elattar, I. A., & Ashamallah, A. (1997) · The Journal of Urology · doi:10.1016/s0022-5347(01)64487-2 · Cited by 447
Andersen, H. K., Lewis, S. J., & Thomas, S. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004080.pub2 · Cited by 369
Slim, K., Vicaut, E., Launay-Savary, M.-V., Contant, C., & Chipponi, J. (2009) · Annals of Surgery · doi:10.1097/sla.0b013e318193425a · Cited by 365
King, P. M., Blazeby, J. M., Ewings, P., Franks, P. J., Longman, R. J., Kendrick, A. H., Kipling, R. M., & Kennedy, R. H. (2006) · Journal of British Surgery · doi:10.1002/bjs.5216 · Cited by 356
Pre‐operative oral carbohydrate loading in colorectal surgery: a randomized controlled trial
Noblett, S. E., Watson, D. S., Huong, H., Davison, B., Hainsworth, P. J., & Horgan, A. F. (2006) · Colorectal Disease · doi:10.1111/j.1463-1318.2006.00965.x · Cited by 352
Mechanical bowel preparation for elective colorectal surgery: a multicentre randomised trial
Contant, C. M., Hop, W. C., van 't Sant, H. P., Oostvogel, H. J., Smeets, H. J., Stassen, L. P., Neijenhuis, P. A., Idenburg, F. J., Dijkhuis, C. M., Heres, P., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61905-9 · Cited by 326
Preoperative oral carbohydrate administration reduces postoperative insulin resistance
Nygren, J., Soop, M., Thorell, A., Efendic, S., Nair, K. S., & Ljungqvist, O. (1998) · Clinical Nutrition · doi:10.1016/s0261-5614(98)80307-5 · Cited by 313
Mechanical Bowel Preparation for Elective Colorectal Surgery: A Meta-analysis
Bucher, P. (2004) · Archives of Surgery · doi:10.1001/archsurg.139.12.1359 · Cited by 301
Eskicioglu, C., Forbes, S. S., Aarts, M.-A., Okrainec, A., & McLeod, R. S. (2009) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-009-0927-2 · Cited by 294
Perioperative nutritional support: a randomised clinical trial
Von Meyenfeldt, M. F., Meijerink, W. J. H. J., Rouflart, M. M. J., Builmaassen, M. T. H. J., & Soeters, P. B. (1992) · Clinical Nutrition · doi:10.1016/0261-5614(92)90026-m · Cited by 279
Fast-track vs standard care in colorectal surgery: a meta-analysis update
Gouvas, N., Tan, E., Windsor, A., Xynos, E., & Tekkis, P. P. (2009) · International Journal of Colorectal Disease · doi:10.1007/s00384-009-0703-5 · Cited by 273
Multimodal Approach to Control Postoperative Pathophysiology and Rehabilitation
KEHLET, H. (1998) · Survey of Anesthesiology · doi:10.1097/00132586-199808000-00048 · Cited by 253
Gregg, J. R., Cookson, M. S., Phillips, S., Salem, S., Chang, S. S., Clark, P. E., Davis, R., Stimson, C. J., Aghazadeh, M., Smith, J. A., et al. (2011) · Journal of Urology · doi:10.1016/j.juro.2010.09.021 · Cited by 247
Miettinen, P. J. R., Laitinen, S. T., Mäkelä, J. T., & Pääkkönen, M. E. (2000) · Diseases of the Colon & Rectum · doi:10.1007/bf02235585 · Cited by 234
Svanfeldt, M., Thorell, A., Hausel, J., Soop, M., Rooyackers, O., Nygren, J., & Ljungqvist, O. (2007) · British Journal of Surgery · doi:10.1002/bjs.5919 · Cited by 219
Gum Chewing Enhances Early Recovery from Postoperative Ileus After Laparoscopic Colectomy1
Asao, T., Kuwano, H., Nakamura, J.-I., Morinaga, N., Hirayama, I., & Ide, M. (2002) · Journal of the American College of Surgeons · doi:10.1016/s1072-7515(02)01179-1 · Cited by 218
Preoperative fasting for preventing perioperative complications in children
Brady, M. C., Kinn, S., Ness, V., O'Rourke, K., Randhawa, N., & Stuart, P. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005285.pub2 · Cited by 210
Implementation of ERAS and how to overcome the barriers
Kahokehr, A., Sammour, T., Zargar-Shoshtari, K., Thompson, L., & Hill, A. G. (2009) · International Journal of Surgery · doi:10.1016/j.ijsu.2008.11.004 · Cited by 207
Introduction of an enhanced recovery protocol for radical cystectomy
Arumainayagam, N., McGrath, J., Jefferson, K. P., & Gillatt, D. A. (2008) · BJU International · doi:10.1111/j.1464-410x.2007.07319.x · Cited by 190
Enhanced Recovery After Surgery: The Future of Improving Surgical Care
Varadhan, K. K., Lobo, D. N., & Ljungqvist, O. (2010) · Critical Care Clinics · doi:10.1016/j.ccc.2010.04.003 · Cited by 187
Soop, M., Carlson, G. L., Hopkinson, J., Clarke, S., Thorell, A., Nygren, J., & Ljungqvist, O. (2004) · British Journal of Surgery · doi:10.1002/bjs.4642 · Cited by 177
Acute Pain Induces Insulin Resistance in Humans
Greisen, J., Juhl, C. B., Grøfte, T., Vilstrup, H., Jensen, T. S., & Schmitz, O. (2001) · Anesthesiology · doi:10.1097/00000542-200109000-00007 · Cited by 176
Preoperative oral carbohydrate nutrition: an update
Nygren, J., Thorell, A., & Ljungqvist, O. (2001) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/00075197-200107000-00002 · Cited by 173
Fast Track Program in Patients Undergoing Radical Cystectomy: Results in 362 Consecutive Patients
Pruthi, R. S., Nielsen, M., Smith, A., Nix, J., Schultz, H., & Wallen, E. M. (2010) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2009.09.026 · Cited by 169
Implementation of a Fast-Track Perioperative Care Program: What Are the Difficulties?
Polle, S. W., Wind, J., Fuhring, J. W., Hofland, J., Gouma, D. J., & Bemelman, W. A. (2007) · Digestive Surgery · doi:10.1159/000108327 · Cited by 165
Gum Chewing Reduces Ileus After Elective Open Sigmoid Colectomy
Schuster, R. (2006) · Archives of Surgery · doi:10.1001/archsurg.141.2.174 · Cited by 161
Oldman, G. (1999) · Medical Entomology and Zoology · Cited by 158
Gum chewing reduces postoperative ileus? A systematic review and meta-analysis
Noble, E. J., Harris, R., Hosie, K. B., Thomas, S. J., & Lewis, S. J. (2009) · International Journal of Surgery · doi:10.1016/j.ijsu.2009.01.006 · Cited by 156
Uchida, I., ASOH, T., Shirasaka, C., & Tsuji, H. (1988) · British journal of surgery · doi:10.1002/bjs.1800750618 · Cited by 145
Fitzgerald, J. E. F., & Ahmed, I. (2009) · World Journal of Surgery · doi:10.1007/s00268-009-0104-5 · Cited by 144
Bowel Preparation Is Associated With Spillage of Bowel Contents in Colorectal Surgery
Mahajna, A., Krausz, M. M., Rosin, D., Shabtai, M., Hershko, D., Ayalon, A., & Zmora, O. (2005) · Diseases of the Colon & Rectum · doi:10.1007/s10350-005-0073-1 · Cited by 134
Preoperative oral carbohydrate treatment attenuates endogenous glucose release 3 days after surgery
Soop, M., Nygren, J., Thorell, A., Weidenhielm, L. R. A., Lundberg, M., Hammarqvist, F., & Ljungqvist, O. H. (2004) · Clinical Nutrition · doi:10.1016/j.clnu.2003.12.007 · Cited by 133
Quah, H. M., Samad, A., Neathey, A. J., Hay, D. J., & Maw, A. (2005) · Colorectal Disease · doi:10.1111/j.1463-1318.2005.00884.x · Cited by 120
The effect of pre-operative glucose loading on postoperative nitrogen metabolism
Crowe, P. J., Dennison, A. R., & Royle, G. T. (1984) · British journal of surgery · doi:10.1002/bjs.1800710828 · Cited by 113
Matros, E., Rocha, F. G., Zinner, M. J., et al. (2006) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2006.02.009 · Cited by 110
One-Day Admission for Lung Lobectomy: An Incidental Result of a Clinical Pathway
Tovar, E. A., Roethe, R. A., Weissig, M. D., et al. (1998) · The Annals of Thoracic Surgery · doi:10.1016/s0003-4975(97)01381-7 · Cited by 106
Infrarenal aortic surgery with a 3-day hospital stay: A report on success with a clinical pathway
Podore, P. C., & Throop, E. B. (1999) · Journal of Vascular Surgery · doi:10.1016/s0741-5214(99)70204-1 · Cited by 99
Purkayastha, S., Tilney, H. S., Darzi, A. W., & Tekkis, P. P. (2008) · Archives of Surgery · doi:10.1001/archsurg.143.8.788 · Cited by 96
Correia, M. I., Caiaffa, W. T., da Silva, A. L., & Waitzberg, D. L. (2001) · PubMed · Cited by 85
Donat, S. M., Slaton, J. W., Pisters, L. L., & Swanson, D. A. (1999) · The Journal of Urology · doi:10.1016/s0022-5347(05)68175-x · Cited by 76
Gum-chewing stimulates bowel motility after surgery for colorectal cancer.
Hirayama, I., Suzuki, M., Ide, M., Asao, T., & Kuwano, H. (2006) · PubMed · Cited by 75
The impact of early nutrition on metabolic response and postoperative ileus
Correia, M. I. T. D., & da Silva, R. G. (2004) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/00075197-200409000-00011 · Cited by 70
Preoperative fasting for preventing perioperative complications in children
Brady, M., Kinn, S., O’Rourke, K., Randhawa, N., & Stuart, P. (2005) · doi:10.1002/14651858.cd005285 · Cited by 61
Perceptions of the Application of Fast-Track Surgical Principles by General Surgeons
Walter, C. J., Smith, A., & Guillou, P. J. (2006) · Annals of The Royal College of Surgeons of England · doi:10.1308/003588406x94940 · Cited by 55
Osland, E., Yunus, R. M., Khan, S., & Memon, M. A. (2009) · Journal of Gastrointestinal Surgery · doi:10.1007/s11605-009-0846-2 · Cited by 52
Parnaby, C. N., MacDonald, A. J., & Jenkins, J. T. (2009) · International Journal of Colorectal Disease · doi:10.1007/s00384-009-0661-y · Cited by 45
Changes in body composition, muscle function and energy expenditure after radical cystectomy
Mathur, S., Plank, L. D., Hill, A. G., Rice, M. A., & Hill, A. G. (2007) · British Journal of Urology · doi:10.1111/j.1464-410x.2007.07337.x · Cited by 44
Improvement of an Enhanced Recovery Protocol for Radical Cystectomy
Koupparis, A. J., Dunn, J., Gillatt, D. A., et al. (2010) · British Journal of Medical and Surgical Urology · doi:10.1016/j.bjmsu.2010.02.007 · Cited by 28
Self-citationKim, H. J., Yoon, Y. M., & Park, K. N. (1994) · Journal of Korean Medical Science · doi:10.3346/jkms.1994.9.5.388 · Cited by 18
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Metadata
- Authors
- Melnyk, M., Casey, R. G., Black, P., & Koupparis, A. J.
- Venue
- Canadian Urological Association Journal
- Published
- 2011-10-01
- Volume
- 5
- Issue
- 5
- Pages
- 342-348
- ISSN
- 1911-6470 (ISSN-L)
- 1920-1214
- OpenAlex
- W2105963978
- Cited by
- 384
- References
- 69
- FWCI
- 5.42
- Type
- journal article
- Language
- en
- Open access
- diamond
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