Cited by 122Fatty Acid Research and HealthAdipose Tissue and MetabolismSeaweed-derived Bioactive Compounds

Effect of Medium-chain Triacylglycerols on Anti-obesity Effect of Fucoxanthin

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Maeda, Hayato, Hosokawa, Masashi, Sashima, Tokutake, Funayama, Katsura, Miyashita, Kazuo·2007·Journal of Oleo Science

Abstract

Dietary effects of medium-chain triacylglycerols (MCT) and fucoxanthin (Fc) on abdominal fat weight were determined using KK-Ay obese mouse. Experimental diet contained MCT(0.9%), Fc (0.1%), or MCT (0.9%) +Fc (0.1%). The abdominal fat weight of mice fed with Fc was significantly lower than that of mice fed with MCT. Uncoupling protein 1 (UCP1), a key molecule for metabolic thermogenesis, was clearly expressed in the white adipose tissue (WAT) of mice fed Fc, but little expression in that of the mice fed MCT. The anti-obesity effect of Fc was increased by mixing Fc with MCT. This increase would be due to the increase in the absorption rate of Fc by MCT.

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  1. Che, Man, Y.B.; Manaf, M.A. Medium-chain triacylglyc- erols in Nutraceutical and Specialty Lipids and Their Co-products. (Shahidi, F. ed.). Taylor & Fransis, Boca Roton, FL, pp. 27-56 (2006).

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Authors
Maeda, H., Hosokawa, M., Sashima, T., Funayama, K., & Miyashita, K.
Affiliations
  • Hokkaido University (JP)
  • Riken Vitamin Co., Ltd. (Japan) (JP)
Venue
Journal of Oleo Science
Published
2007
Volume
56
Issue
12
Pages
615-621
ISSN
  • 1341-8327 (ISSN-L)
  • 1345-8957
  • 1347-3352
OpenAlex
W1983741471
Cited by
122
References
21
Citations by year
2026: 2 · 2025: 3 · 2024: 5 · 2023: 6 · 2022: 5 · 2021: 8 · 2020: 11 · 2019: 6 · 2018: 11 · 2017: 10 · 2016: 7 · 2015: 8 · 2014: 11 · 2013: 5 · 2012: 4
FWCI
3.09
Type
journal article
Language
en
Open access
Locations
  • Journal of Oleo Science (publishedVersion)
  • PubMed (publishedVersion)
Funders
Ministry of Education, Culture, Sports, Science and Technology
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
  • Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Keywords
medium-chain triglycerides, fucoxanthin, anti-obesity, abdominal fat, UCP1, thermogenesis, white adipose tissue, dietary fat absorption
MeSH terms
Adipose Tissue, Animals, Dietary Fats, Female, Intestinal Absorption, Obesity, Triglycerides, Leptin, Xanthophylls, Abdominal Fat, Mice

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