Cited by 114Sleep and related disordersHeart Rate Variability and Autonomic ControlSleep and Wakefulness Research

Short-term stability of sleep and heart rate variability in good sleepers and patients with insomnia: for some measures, one night is enough

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Israel, Benjamin, Buysse, Daniel J., Krafty, Robert T., Begley, Amy, Miewald, Jean, Hall, Martica·2012·Sleep

Abstract

STUDY OBJECTIVES: Quantify the short-term stability of multiple indices of sleep and nocturnal physiology in good sleeper controls and primary insomnia patients. DESIGN: Intra-class correlation coefficients (ICC) were used to quantify the short-term stability of study outcomes. SETTING: Sleep laboratory. PARTICIPANTS: Fifty-four adults with primary insomnia (PI) and 22 good sleeper controls (GSC). MEASUREMENTS: Visually scored sleep outcomes included indices of sleep duration, continuity, and architecture. Quantitative EEG outcomes included power in the delta, theta, alpha, sigma, and beta bands during NREM sleep. Power spectral analysis was used to estimate high-frequency heart rate variability (HRV) and the ratio of low- to high-frequency HRV power during NREM and REM sleep. RESULTS: With the exception of percent stage 3+4 sleep; visually scored sleep outcomes did not exhibit short-term stability across study nights. Most QEEG outcomes demonstrated short-term stability in both groups. Although power in the beta band was stable in the PI group (ICC = 0.75), it tended to be less stable in GSCs (ICC = 0.55). Both measures of cardiac autonomic tone exhibited short-term stability in GSCs and PIs during NREM and REM sleep. CONCLUSIONS: Most QEEG bandwidths and HRV during sleep show high short-term stability in good sleepers and patients with insomnia alike. One night of data is, thus, sufficient to derive reliable estimates of these outcomes in studies focused on group differences or correlates of QEEG and/or HRV. In contrast, one night of data is unlikely to generate reliable estimates of PSG-assessed sleep duration, continuity or architecture, with the exception of slow wave sleep.

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Research works printed but not linked: 2

  1. Buckelmuller J, Landolt HP, Stassen HH, Achermann P. Trait-like indi- vidual differences in the human sleep EEG. Neuroscience 2006;138:351-6.
  2. Pardo Y, Merz CN, Paul-Labrador M, et al. Heart rate variability repro- ducibility and stability using commercially available equipment in coro- nary artery disease with daily life myocardial ischemia. Am J Cardiol 1996;78:866-70.

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Authors
Israel, B., Buysse, D. J., Krafty, R. T., Begley, A., Miewald, J., & Hall, M.
Affiliations
University of Pittsburgh (US)
Corresponding author
Hall, Martica
Venue
Sleep
Published
2012-09
Volume
35
Issue
9
Pages
1285-1291
ISSN
  • 0161-8105 (ISSN-L)
  • 1550-9109
OpenAlex
W1964973114
Cited by
114
References
75
Citations by year
2026: 8 · 2025: 9 · 2024: 9 · 2023: 7 · 2022: 8 · 2021: 11 · 2020: 5 · 2019: 8 · 2018: 5 · 2017: 4 · 2016: 14 · 2015: 13 · 2014: 8 · 2013: 5
FWCI
11.16
Type
journal article
Language
en
Open access
Locations
  • SLEEP (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (HL082610, HL104607)
  • National Heart, Lung, and Blood Institute (HL104607, HL082610, R01HL104607, T32HL082610)
  • National Institute of Mental Health (R01MH024652, MH024652, R37MH024652)
  • National Center for Research Resources (RR 000056, M01RR000056, UL1RR024153)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Keywords
primary insomnia, short-term stability, intra-class correlation, sleep architecture, sleep continuity, sleep duration, quantitative EEG, EEG spectral analysis, heart rate variability, cardiac autonomic tone, NREM sleep, REM sleep, slow-wave sleep, good sleepers
MeSH terms
Adult, Electroencephalography, Female, Heart Rate, Humans, Sleep Initiation and Maintenance Disorders, Male, Sleep, Sleep Stages, Polysomnography

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