Insomnia disorder
Abstract
Insomnia disorder affects a large proportion of the population on a situational, recurrent or chronic basis and is among the most common complaints in medical practice. The disorder is predominantly characterized by dissatisfaction with sleep duration or quality and difficulties initiating or maintaining sleep, along with substantial distress and impairments of daytime functioning. It can present as the chief complaint or, more often, co-occurs with other medical or psychiatric disorders, such as pain and depression. Persistent insomnia has been linked with adverse long-term health outcomes, including diminished quality of life and physical and psychological morbidity. Despite its high prevalence and burden, the aetiology and pathophysiology of insomnia is poorly understood. In the past decade, important changes in classification and diagnostic paradigms have instigated a move from a purely symptom-based conceptualization to the recognition of insomnia as a disorder in its own right. These changes have been paralleled by key advances in therapy, with generic pharmacological and psychological interventions being increasingly replaced by approaches that have sleep-specific and insomnia-specific therapeutic targets. Psychological and pharmacological therapies effectively reduce the time it takes to fall asleep and the time spent awake after sleep onset, and produce a modest increase in total sleep time; these are outcomes that correlate with improvements in daytime functioning. Despite this progress, several challenges remain, including the need to improve our knowledge of the mechanisms that underlie insomnia and to develop more cost-effective, efficient and accessible therapies.
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In general populations, 10-15% of adults have at least one nighttime sleep-related and one daytime fatigue-related symptom of insomnia.
“the consensus from those studies is that 30–36% of adults report having at least one nighttime sleep-related symptom of insomnia, while 10–15% of the population has at least one nighttime sleep-related and one daytime fatigue-related symptom of insomnia [26,37].”
From The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review (2024) · cites this paper as [26]
In general populations, 30-36% of adults report at least one nighttime sleep-related symptom of insomnia.
“the consensus from those studies is that 30–36% of adults report having at least one nighttime sleep-related symptom of insomnia, while 10–15% of the population has at least one nighttime sleep-related and one daytime fatigue-related symptom of insomnia [26,37].”
From The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review (2024) · cites this paper as [26]
The prevalence of poor sleep quality in firefighters is typically higher than the general population of the area.
“Thus, the prevalence of poor sleep quality ranges depending on the assessment and the working schedule of the firefighters but is typically higher than the general population of the area [10,11,26,45].”
From The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review (2024) · cites this paper as [26]
There is a strong amount of evidence linking insomnia as a risk factor for depression.
“There is a strong amount of evidence linking insomnia as a risk factor for depression [26].”
From The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review (2024) · cites this paper as [26]
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Jespersen, K. V., Stevner, A. B. A., Fernandes, H. M., Sørensen, S. D., Someren, E. J. W. V., Kringelbach, M. L., & Vuust, P. (2019) · Journal of Sleep Research · doi:10.1111/jsr.12901 · Cited by 44 · see citing works
Harvey, A. G., Dong, L., Bélanger, L., & Morin, C. M. (2017) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000244 · Cited by 43 · see citing works
Self-citationWei, Y., Ramautar, J. R., Colombo, M. A., Lindert, B. H. W. T., & Someren, E. J. W. V. (2018) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00395 · Cited by 43 · see citing works
Barateau, L., Pizza, F., Chenini, S., Peter‐Derex, L., & Dauvilliers, Y. A. (2023) · Revue Neurologique · doi:10.1016/j.neurol.2023.08.001 · Cited by 42 · see citing works
The heritability of insomnia: Systematic review and meta-analysis of twin studies
Madrid‐Valero, J. J., Rubio‐Aparicio, M., Gregory, A. M., Sánchez‐Meca, J., & Ordoñana, J. R. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101437 · Cited by 42 · see citing works
- Authors
- Morin, C. M., Drake, C. L., Harvey, A. G., Krystal, A. D., Manber, R., Riemann, D., & Spiegelhalder, K.
- Affiliations
- Université Laval (CA)
- Henry Ford Hospital (US)
- University of California, Berkeley (US)
- Duke University (US)
- Stanford Medicine (US)
- University of Freiburg (DE)
- Corresponding author
- Morin, Charles M.
- ORCID
- Venue
- Nature Reviews Disease Primers
- Published
- 2015-09-03
- Volume
- 1
- Issue
- 1
- Pages
- 15026-15026
- ISSN
- 2056-676X (ISSN-L)
- OpenAlex
- W4211107190
- Cited by
- 746
- References
- 191
- Citations by year
- 2026: 72 · 2025: 120 · 2024: 111 · 2023: 119 · 2022: 97 · 2021: 75 · 2020: 65 · 2019: 34 · 2018: 20 · 2017: 23 · 2016: 6 · 2015: 4
- FWCI
- 2.28
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Nature Reviews Disease Primers (publishedVersion)
- PubMed (publishedVersion)
- Corpus Université Laval (Université Laval) (submittedVersion)
- Funders
- Canadian Institutes of Health Research (MOP42504)
- National Institute of Mental Health (R01MH091053, R01MH105513)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- insomnia, sleep onset insomnia, sleep maintenance insomnia, insomnia classification, insomnia pathophysiology, insomnia treatment, pharmacotherapy, psychotherapy, quality of life, comorbid depression, chronic insomnia
- MeSH terms
- Activities of Daily Living, Depression, Humans, Sleep Initiation and Maintenance Disorders, Pain, Quality of Life, Stress, Psychological
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