Chiral Drugs. An Overview

Role of Pharmacokinetics and Metabolism in Drug Discovery and Development

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The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias

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Enantioselective Aspects of Drug Action and Disposition: Therapeutic Pitfalls

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Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: An overview

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Stereochemistry in Drug Action

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The importance of stereoselective determination of drugs in the clinical laboratory

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Bioanalysis of drugs by liquid-phase microextraction coupled to separation techniques

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Mechanism of action of barbiturates.

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The specification of asymmetric configuration in organic chemistry

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Chiral Separations By Liquid Chromatography And Related Technologies

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Free Radicals, Antioxidants in Disease and Health

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Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods

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Adsorptive separation on metal–organic frameworks in the liquid phase

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Carbon Nanotubes: Applications in Pharmacy and Medicine

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Pharmacologically active compounds in the environment and their chirality

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Applications of bacterial cellulose in food, cosmetics and drug delivery

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The development of ruthenium( ii ) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications

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Chiral Graphene Quantum Dots

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Geometric deep learning on molecular representations

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Nanophotonic Approaches for Chirality Sensing

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Chiral AIEgens – Chiral recognition, CPL materials and other chiral applications

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Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury

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Chiral carbon dots: synthesis, optical properties, and emerging applications

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Global risk of pharmaceutical contamination from highly populated developing countries

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Lateral chirality-sorting optical forces

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Chirality of New Drug Approvals (2013–2022): Trends and Perspectives

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Enantiospecific Optical Enhancement of Chiral Sensing and Separation with Dielectric Metasurfaces

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The Role of Plasmon-Generated Near Fields for Enhanced Circular Dichroism Spectroscopy

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Ketamine as an antidepressant: Overview of its mechanisms of action and potential predictive biomarkers

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Enhanced Chiral Sensing with Dielectric Nanoresonators

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Applications of OR/ECD/VCD to the structure elucidation of natural products

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D‐Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection

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Chiral Supraparticles for Controllable Nanomedicine

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Metallogels: Availability, Applicability, and Advanceability

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Expedited mapping of the ligandable proteome using fully functionalized enantiomeric probe pairs

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High Quality Factor Dielectric Metasurfaces for Ultraviolet Circular Dichroism Spectroscopy

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Chiral Separations

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Self-assembly of AIEgens

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Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers

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Chirality-assisted lateral momentum transfer for bidirectional enantioselective separation

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Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods

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Chiral Seeded Growth of Gold Nanorods Into Fourfold Twisted Nanoparticles with Plasmonic Optical Activity

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Accessible Superchiral Near-Fields Driven by Tailored Electric and Magnetic Resonances in All-Dielectric Nanostructures

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Polarization control in an X-ray free-electron laser

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Circular Dichroism Studies on Plasmonic Nanostructures

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All-Optical Chirality-Sensitive Sorting via Reversible Lateral Forces in Interference Fields

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Chiral assembly of organic luminogens with aggregation-induced emission

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Controlled partial interpenetration in metal–organic frameworks

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Chirality Transfer from Sub‐Nanometer Biochemical Molecules to Sub‐Micrometer Plasmonic Metastructures: Physiochemical Mechanisms, Biosensing, and Bioimaging Opportunities

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Chiral plasmonic nanostructures: recent advances in their synthesis and applications

Wu, W., & Pauly, M. (2021) · Materials Advances · doi:10.1039/d1ma00915j · Cited by 152

Chiral Switch: Between Therapeutical Benefit and Marketing Strategy

Hancu, G., & Modroiu, A. (2022) · Pharmaceuticals · doi:10.3390/ph15020240 · Cited by 140

Enhancing Enantioselective Absorption Using Dielectric Nanospheres

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Imaging in-vivo tau pathology in Alzheimer’s disease with THK5317 PET in a multimodal paradigm

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Solid membranes for chiral separation: A review

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A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination

Zhu, S., Niljianskul, N., & Buchwald, S. L. (2016) · Nature Chemistry · doi:10.1038/nchem.2418 · Cited by 126

Ultrasound experiments on acoustical activity in chiral mechanical metamaterials

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An emerging class of hyperbolic lattice exhibiting tunable elastic properties and impact absorption through chiral twisting

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An Enantioselective e‐Nose: An Array of Nanoporous Homochiral MOF Films for Stereospecific Sensing of Chiral Odors

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Stereodynamic Strategies to Induce and Enrich Chirality of Atropisomers at a Late Stage

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Circular dichroism induced by Fano resonances in planar chiral oligomers

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Advances and applications of chiral resolution in pharmaceutical field

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Hot Electron Generation and Cathodoluminescence Nanoscopy of Chiral Split Ring Resonators

Fang, Y., Verre, R., Shao, L., et al. (2016) · Nano Letters · doi:10.1021/acs.nanolett.6b02154 · Cited by 112

Chiral pharmaceuticals: Environment sources, potential human health impacts, remediation technologies and future perspective

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Multimodal Role of Amino Acids in Microbial Control and Drug Development

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Chiral Mesostructured Inorganic Materials with Optical Chiral Response

Duan, Y., & Che, S. (2022) · Advanced Materials · doi:10.1002/adma.202205088 · Cited by 112

Advances in Recombinant Lipases: Production, Engineering, Immobilization and Application in the Pharmaceutical Industry

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Enantioselective Recognition of Ammonium Carbamates in a Chiral Metal–Organic Framework

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Enantiomeric Recognition and Separation by Chiral Nanoparticles

Gogoi, A., Mazumder, N., Konwer, S., Ranawat, H. M., Chen, N., & Zhuo, G. (2019) · Molecules · doi:10.3390/molecules24061007 · Cited by 103

Chiral Nanoceramics

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The significance of chirality in contemporary drug discovery-a mini review

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Racemic drug resolution: a comprehensive guide

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Field detection devices for screening the quality of medicines: a systematic review

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Achiral, Helicity Preserving, and Resonant Structures for Enhanced Sensing of Chiral Molecules

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Deep Generative Models in De Novo Drug Molecule Generation

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Recent Advances in 1,2,4‐Triazole Scaffolds as Antiviral Agents

El‐Sebaey, S. A. (2020) · ChemistrySelect · doi:10.1002/slct.202002830 · Cited by 98

Chiral Macrocycles for Enantioselective Recognition

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Substrate-Specificity of Candida rugosa Lipase and Its Industrial Application

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Experimental and Theoretical Observation of Photothermal Chirality in Gold Nanoparticle Helicoids

Miandashti, A. R., Khorashad, L. K., Kordesch, M. E., et al. (2020) · ACS Nano · doi:10.1021/acsnano.9b09062 · Cited by 92

Using chiral liquid chromatography quadrupole time-of-flight mass spectrometry for the analysis of pharmaceuticals and illicit drugs in surface and wastewater at the enantiomeric level

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Chiral Drug Analysis in Forensic Chemistry: An Overview

Ribeiro, C. M. R., dos Santos, C. R. M., Gonçalves, V., Ramos, A., Afonso, C., & Tiritan, M. E. (2018) · Molecules · doi:10.3390/molecules23020262 · Cited by 89

Enantioselective activity of usnic acid: a comprehensive review and future perspectives

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Unveiling the Hidden Performance of Whole Cells in the Asymmetric Bioreduction of Aryl‐containing Ketones in Aqueous Deep Eutectic Solvents

Vitale, P., Abbinante, V. M., Perna, F. M., Salomone, A., Cardellicchio, C., & Capriati, V. (2016) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.201601064 · Cited by 87

Long- and short-ranged chiral interactions in DNA-assembled plasmonic chains

Martens, K., Binkowski, F., Nguyen, L., Hu, L., Govorov, A. O., Burger, S., & Liedl, T. (2021) · Nature Communications · doi:10.1038/s41467-021-22289-8 · Cited by 85

Advances of Vibrational Circular Dichroism (VCD) in bioanalytical chemistry. A review

Kurouski, D. (2017) · Analytica Chimica Acta · doi:10.1016/j.aca.2017.08.014 · Cited by 85

Enantioselective Synthesis of Secondary β-Trifluoromethyl Alcohols via Catalytic Asymmetric Reductive Trifluoroalkylation and Diastereoselective Reduction

Wu, B., Xu, J., Bian, K., et al. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c01422 · Cited by 85

Chirality sorting using two-wave-interference–induced lateral optical force

Chen, H., Liang, C., Liu, S., & Lin, Z. (2016) · Physical Review A · doi:10.1103/physreva.93.053833 · Cited by 83

Synthesis of Both Enantiomers of Nine‐Membered CF 3 ‐Substituted Heterocycles Using a Single Chiral Ligand: Palladium‐Catalyzed Decarboxylative Ring Expansion with Kinetic Resolution

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Recent Advances in Organocatalytic Asymmetric Michael Addition Reactions to α, β‐Unsaturated Nitroolefins

Das, T., Mohapatra, S., Mishra, N. P., et al. (2021) · ChemistrySelect · doi:10.1002/slct.202100679 · Cited by 82

Demystifying racemic natural products in the homochiral world

Bitchagno, G. T. M., Nchiozem‐Ngnitedem, V., Melchert, D., et al. (2022) · Nature Reviews Chemistry · doi:10.1038/s41570-022-00431-4 · Cited by 82

Enantioselectivity of mass spectrometry: Challenges and promises

Awad, H., & El‐Aneed, A. (2013) · Mass Spectrometry Reviews · doi:10.1002/mas.21379 · Cited by 82

From stroke to neurodegenerative diseases: The multi-target neuroprotective effects of 3-n-butylphthalide and its derivatives

Huang, L., Wang, S., Ma, F., Zhang, Y., Peng, Y., Xing, C., Feng, Y., Wang, X., & Peng, Y. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.08.007 · Cited by 80

Transition metal catalyzed asymmetric multicomponent reactions of unsaturated compounds using organoboron reagents

Das, K. K., Manna, S., & Panda, S. (2020) · Chemical Communications · doi:10.1039/d0cc06460b · Cited by 81

Lateral sorting of chiral nanoparticles using Fano-enhanced chiral force in visible region

Cao, T., & Qiu, Y. (2017) · Nanoscale · doi:10.1039/c7nr05464e · Cited by 78

Fluorescence-Detected Circular Dichroism of a Chiral Molecular Monolayer with Dielectric Metasurfaces

Solomon, M. L., Abendroth, J. M., Poulikakos, L. V., Hu, J., & Dionne, J. A. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c07140 · Cited by 79

Selective Orientation of Chiral Molecules by Laser Fields with Twisted Polarization

Tutunnikov, I., Gershnabel, E., Gold, S., et al. (2018) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.7b03416 · Cited by 76

Bottom-Up Engineering of Responsive Hydrogel Materials for Molecular Detection and Biosensing

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The molecularly imprinted polymer essentials: curation of anticancer, ophthalmic, and projected gene therapy drug delivery systems

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Chip-Based High-Performance Liquid Chromatography for High-Speed Enantioseparations

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Cofactor F420: an expanded view of its distribution, biosynthesis and roles in bacteria and archaea

Grinter, R., & Greening, C. (2021) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuab021 · Cited by 78

Catalytic Enantioselective Flow Processes with Solid‐Supported Chiral Catalysts

Rodríguez‐Escrich, C., & Pericàs, M. À. (2018) · The Chemical Record · doi:10.1002/tcr.201800097 · Cited by 73

A Chiral Emissive Conjugated Corral for High‐Affinity and Highly Enantioselective Recognition in Water

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Optical sorting of small chiral particles by tightly focused vector beams

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Catalytic Asymmetric Synthesis of Chiral Caged Hydrocarbons as Arenes Bioisosteres

Yang, X.-C., Wang, J., Xiao, Y., & Feng, J. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202505803 · Cited by 73

Biomimetic photonic materials derived from chitin and chitosan

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Enlightening dynamic functions in molecular systems by intrinsically chiral light-driven molecular motors

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