The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications
Open accessAbstract
A modification and inducing endothelial cell inflammatory response as well as atherosclerotic plaque formation. Decreased expression of METTL14 can inhibit endothelial inflammation and atherosclerosis development. Therefore, METTL14 may serve as a potential target for the clinical treatment of atherosclerosis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
Dominissini, D., Moshitch-Moshkovitz, S., Schwartz, S., Salmon-Divon, M., Ungar, L., Osenberg, S., Cesarkas, K., Jacob-Hirsch, J., Amariglio, N., Kupiec, M., et al. (2012) · Nature · doi:10.1038/nature11112 · Cited by 4,884
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
Meyer, K. D., Saletore, Y., Zumbo, P., Elemento, O., Mason, C. E., & Jaffrey, S. R. (2012) · Cell · doi:10.1016/j.cell.2012.05.003 · Cited by 4,223
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
Wang, X., Zhao, B. S., Roundtree, I. A., Lu, Z., Han, D., Ma, H., Weng, X., Chen, K., Shi, H., & He, C. (2015) · Cell · doi:10.1016/j.cell.2015.05.014 · Cited by 3,483
Self-citationEndothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
Gimbrone, M. A., & García-Cardeña, G. (2016) · Circulation Research · doi:10.1161/circresaha.115.306301 · Cited by 3,476
Dynamic RNA Modifications in Gene Expression Regulation
Roundtree, I. A., Evans, M. E., Pan, T., & He, C. (2017) · Cell · doi:10.1016/j.cell.2017.05.045 · Cited by 3,399
Post-transcriptional gene regulation by mRNA modifications
Zhao, B. S., Roundtree, I. A., & He, C. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.132 · Cited by 2,420
Gene expression regulation mediated through reversible m6A RNA methylation
Fu, Y., Dominissini, D., Rechavi, G., & He, C. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3724 · Cited by 1,935
Zhang, S., Zhao, B. S., Zhou, A., Lin, K., Zheng, S., Lu, Z., Chen, Y., Sulman, E. P., Xie, K., Bögler, O., et al. (2017) · Cancer Cell · doi:10.1016/j.ccell.2017.02.013 · Cited by 1,459
Métivier, R., Penot, G., Hübner, M. R., Reid, G., Brand, H., Koš, M., & Gannon, F. (2003) · Cell · doi:10.1016/s0092-8674(03)00934-6 · Cited by 1,431
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
Wang, P., Doxtader, K. A., & Nam, Y. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.05.041 · Cited by 1,246
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
Paik, J.-H., Kollipara, R., Chu, G., Ji, H., Xiao, Y., Ding, Z., Miao, L., Tothova, Z., Horner, J. W., Carrasco, D. R., et al. (2007) · Cell · doi:10.1016/j.cell.2006.12.029 · Cited by 1,032
Weng, H., Huang, H., Wu, H., Qin, X., Zhao, B. S., Dong, L., Shi, H., Skibbe, J., Shen, C., Hu, C., et al. (2018) · Cell Stem Cell · doi:10.1016/j.stem.2017.11.016 · Cited by 968
Self-citationRNA N6-methyladenosine methylation in post-transcriptional gene expression regulation
Yue, Y., Liu, J., & He, C. (2015) · Genes & Development · doi:10.1101/gad.262766.115 · Cited by 922
Ma, J., Yang, F., Zhou, C., Liu, F., Yuan, J., Wang, F., Wang, T., Xu, Q., Zhou, W., & Sun, S. (2017) · Hepatology · doi:10.1002/hep.28885 · Cited by 912
Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
Yoon, K.-J., Ringeling, F. R., Vissers, C., Jacob, F., Pokrass, M., Jimenez-Cyrus, D., Su, Y., Kim, N.-S., Zhu, Y., Zheng, L., et al. (2017) · Cell · doi:10.1016/j.cell.2017.09.003 · Cited by 749
Han, J., Wang, J.-Z., Yang, X., Yu, H., Zhou, R., Lu, H.-C., Yuan, W.-B., Lu, J.-C., Zhou, Z.-J., Lu, Q., et al. (2019) · Molecular Cancer · doi:10.1186/s12943-019-1036-9 · Cited by 709
Detecting RNA modifications in the epitranscriptome: predict and validate
Helm, M., & Motorin, Y. (2017) · Nature Reviews Genetics · doi:10.1038/nrg.2016.169 · Cited by 635
FTO-Dependent N 6 -Methyladenosine Regulates Cardiac Function During Remodeling and Repair
Mathiyalagan, P., Adamiak, M., Mayourian, J., Sassi, Y., Liang, Y., Agarwal, N., Jha, D., Zhang, S., Kohlbrenner, E., Chepurko, E., et al. (2019) · Circulation · doi:10.1161/circulationaha.118.033794 · Cited by 598
O’Brien, K. D., McDonald, T. O., Chait, A., Allen, M. D., & Alpers, C. E. (1996) · Circulation · doi:10.1161/01.cir.93.4.672 · Cited by 573
Tang, C., Klukovich, R., Peng, H., Wang, Z., Yu, T., Zhang, Y., Zheng, H., Klungland, A., & Yan, W. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1717794115 · Cited by 539
Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization
Potente, M., Urbich, C., Sasaki, K.-I., Hofmann, W. K., Heeschen, C., Aicher, A., Kollipara, R., DePinho, R. A., Zeiher, A. M., & Dimmeler, S. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23126 · Cited by 531
Structural insights into the molecular mechanism of the m6A writer complex
Śledź, P., & Jinek, M. (2016) · eLife · doi:10.7554/elife.18434 · Cited by 528
The Role of Monocytes in Angiogenesis and Atherosclerosis
Jaipersad, A. S., Lip, G. Y. H., Silverman, S., & Shantsila, E. (2014) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.09.019 · Cited by 451
Interactions, localization, and phosphorylation of the m6A generating METTL3–METTL14–WTAP complex
Schöller, E., Weichmann, F., Treiber, T., Ringle, S., Treiber, N., Flatley, A., Feederle, R., Bruckmann, A., & Meister, G. (2018) · RNA · doi:10.1261/rna.064063.117 · Cited by 439
Selectins: lectins that initiate cell adhesion under flow
McEver, R. P. (2002) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(02)00367-8 · Cited by 413
Endothelial-Dependent Mechanisms of Leukocyte Recruitment to the Vascular Wall
Rao, R. M., Yang, L., Garcia-Cardena, G., & Luscinskas, F. W. (2007) · Circulation Research · doi:10.1161/circresaha.107.151860b · Cited by 394
Abnormal Angiogenesis in Foxo1 (Fkhr)-deficient Mice
Furuyama, T., Kitayama, K., Shimoda, Y., Ogawa, M., Sone, K., Yoshida-Araki, K., Hisatsune, H., Nishikawa, S.-I., Nakayama, K., Nakayama, K., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m314214200 · Cited by 340
Emerging Roles of RNA Modification: m6A and U-Tail
Lee, M., Kim, B., & Kim, V. N. (2014) · Cell · doi:10.1016/j.cell.2014.08.005 · Cited by 335
Analysis of translation using polysome profiling
Chassé, H., Boulben, S., Costache, V., Cormier, P., & Morales, J. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw907 · Cited by 202
Ogg1 -Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis
Tumurkhuu, G., Shimada, K., Dagvadorj, J., Crother, T. R., Zhang, W., Luthringer, D., Gottlieb, R. A., Chen, S., & Arditi, M. (2016) · Circulation Research · doi:10.1161/circresaha.116.308362 · Cited by 181
Self-citationTsuchiya, K., Tanaka, J., Shuiqing, Y., Welch, C. L., DePinho, R. A., Tabas, I., Tall, A. R., Goldberg, I. J., & Accili, D. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.01.018 · Cited by 179
FOXOs and Sirtuins in Vascular Growth, Maintenance, and Aging
Oellerich, M. F., & Potente, M. (2012) · Circulation Research · doi:10.1161/circresaha.111.246488 · Cited by 161
Akhtar, S., Hartmann, P., Karshovska, E., Rinderknecht, F.-A. B., Subramanian, P., Gremse, F., Grommes, J., Jacobs, M. J. H. M., Kiessling, F. M., Weber, C., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05886 · Cited by 157
Endothelial Dysfunction, Hemodynamic Forces, and Atherosclerosis
Gimbrone, M. A. (1999) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1615903 · Cited by 142
EBV epitranscriptome reprogramming by METTL14 is critical for viral-associated tumorigenesis
Lang, F., Singh, R. K., Pei, Y., Zhang, S., Sun, K., & Robertson, E. S. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007796 · Cited by 121
Tumurkhuu, G., Dagvadorj, J., Porritt, R. A., Crother, T. R., Shimada, K., Tarling, E. J., Erbay, E., Arditi, M., & Chen, S. (2018) · Cell Metabolism · doi:10.1016/j.cmet.2018.05.027 · Cited by 93
Deficiency of the NR4A Orphan Nuclear Receptor NOR1 Decreases Monocyte Adhesion and Atherosclerosis
Zhao, Y., Howatt, D. A., Gizard, F., Nomiyama, T., Findeisen, H. M., Heywood, E. B., Jones, K. L., Conneely, O. M., Daugherty, A., & Bruemmer, D. (2010) · Circulation Research · doi:10.1161/circresaha.110.222083 · Cited by 89
Mettl14 is required for mouse postimplantation development by facilitating epiblast maturation
Meng, T., Lu, X., Guo, L., Hou, G.-M., Ma, X., Li, Q., Huang, L., Fan, L., Zhao, Z., Ou, X., et al. (2018) · The FASEB Journal · doi:10.1096/fj.201800719r · Cited by 89
Csiszár, A., Smith, K. E., Labinskyy, N., Orosz, Z. Z., Rivera, A., & Ungvari, Z. I. (2007) · The FASEB Journal · doi:10.1096/fasebj.21.5.a450-a · Cited by 84
ALKBHs-facilitated RNA modifications and de-modifications
Alemu, E. A., He, C., & Klungland, A. (2016) · DNA repair · doi:10.1016/j.dnarep.2016.05.026 · Cited by 71
Xu, Y., Yuan, X. D., Wu, J. J., Chen, R. Y., Xia, L., Zhang, M., Han, C., & Mou, S. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.29258 · Cited by 68
Forkhead factor FoxO1 is essential for placental morphogenesis in the developing embryo
Ferdous, A., Morris, J. A., Abedin, M. J., Collins, S. C., Richardson, J. A., & Hill, J. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1107341108 · Cited by 60
FOXO1 Regulates Dendritic Cell Activity through ICAM-1 and CCR7
Dong, G., Wang, Y., Xiao, W., Pacios, S., Xu, F., Tian, C., Xiao, E., Choi, Y., & Graves, D. T. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1401754 · Cited by 59
Self-citationLee, J., Chen, H., Pullikotil, P., & Quon, M. J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.180661 · Cited by 51
Wang, Y., Wang, R., Yao, B., Hu, T. H., Zhao, L., Liu, Y., Cui, X., Cheng, L., Song, W., Huang, S., et al. (2019) · Science China Life Sciences · doi:10.1007/s11427-019-9826-7 · Cited by 35
Self-citationPKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis
Liu, S., Lai, L., Zuo, Q., Dai, F., Wu, L., Wang, Y., Zhou, Q., Liu, J., Liu, J., Li, L., et al. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.02.007 · Cited by 34
Self-citationBaymaz, H. I., Spruijt, C. G., & Vermeulen, M. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-1142-4_15 · Cited by 31
Menghini, R., Casagrande, V., Cardellini, M., Ballanti, M., Davato, F., Cardolini, I., Stoehr, R., Fabrizi, M., Morelli, M., Anemona, L., et al. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.07.026 · Cited by 28
Jian, R., Yang, M., & Xu, F. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28937 · Cited by 18
Cited by
Potential Therapeutic Targeting of lncRNAs in Cholesterol Homeostasis
Ye, W.-C., Huang, S.-F., Hou, L.-J., Long, H.-J., Yin, K., Hu, C. Y., & Zhao, G.-J. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.688546 · Cited by 19
Insights into the molecular underpinning of type 2 diabetes complications
Singh, A., Bocher, O., & Zeggini, E. (2025) · Human Molecular Genetics · doi:10.1093/hmg/ddae203 · Cited by 10
Metadata
- Authors
- Jian, D., Wang, Y., Jian, L., Tang, H., Rao, L., Chen, K., Jia, Z., Zhang, W., Liu, Y., Chen, X., Shen, X., Gao, C., Wang, S., & Li, M.
- Venue
- Theranostics
- Publisher
- Ivyspring International Publisher
- Published
- 2020
- Volume
- 10
- Issue
- 20
- Pages
- 8939-8956
- ISSN
- 1838-7640 (ISSN-L)
- OpenAlex
- W3043902187
- Cited by
- 281
- References
- 49
- FWCI
- 9.96
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.