The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Nanotheranostics ˗ Application and Further Development of Nanomedicine Strategies for Advanced Theranostics
Open accessAbstract
Nanotheranostics is to apply and further develop nanomedicine strategies for advanced theranostics. This review summarizes the various nanocarriers developed so far in the literature for nanotheranostics, which include polymer conjugations, dendrimers, micelles, liposomes, metal and inorganic nanoparticles, carbon nanotubes, and nanoparticles of biodegradable polymers for sustained, controlled and targeted co-delivery of diagnostic and therapeutic agents for better theranostic effects with fewer side effects. The theranostic nanomedicine can achieve systemic circulation, evade host defenses and deliver the drug and diagnostic agents at the targeted site to diagnose and treat the disease at cellular and molecular level. The therapeutic and diagnostic agents are formulated in nanomedicine as a single theranostic platform, which can then be further conjugated to biological ligand for targeting. Nanotheranostics can also promote stimuli-responsive release, synergetic and combinatory therapy, siRNA co-delivery, multimodality therapies, oral delivery, delivery across the blood-brain barrier as well as escape from intracellular autophagy. The fruition of nanotheranostics will be able to provide personalized therapy with bright prognosis, which makes even the fatal diseases curable or at least treatable at the earliest stage.
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Cites
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Cited by
Kamaly, N., Yameen, B., Wu, J., & Farokhzad, O. C. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00346 · Cited by 3,070
siRNA Delivery Strategies: A Comprehensive Review of Recent Developments
Tatiparti, K., Sau, S., Kashaw, S., & Iyer, A. (2017) · Nanomaterials · doi:10.3390/nano7040077 · Cited by 429
Skin cancer and new treatment perspectives: A review
Simões, M. C. F., Sousa, J. J. S., & Pais, A. A. C. C. (2015) · Cancer Letters · doi:10.1016/j.canlet.2014.11.001 · Cited by 414
Gut microbiota and cardiovascular disease: opportunities and challenges
Kazemian, N., Mahmoudi, M., Halperin, F., Wu, J. C., & Pakpour, S. (2020) · Microbiome · doi:10.1186/s40168-020-00821-0 · Cited by 384
Wang, D., Lee, M. M. S., Shan, G., Kwok, R. T. K., Lam, J. W. Y., Su, H., Cai, Y., & Tang, B. Z. (2018) · Advanced Materials · doi:10.1002/adma.201802105 · Cited by 365
Metadata
- Authors
- Muthu, M. S., Leong, D. T., Mei, L., & Feng, S.-S.
- Venue
- Theranostics
- Publisher
- Ivyspring International Publisher
- Published
- 2014
- Volume
- 4
- Issue
- 6
- Pages
- 660-677
- ISSN
- 1838-7640 (ISSN-L)
- OpenAlex
- W2108747405
- Cited by
- 603
- References
- 10
- FWCI
- 24.02
- Type
- journal article
- Language
- en
- Open access
- gold
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