Cited by 399Antibiotic Resistance in BacteriaMicrobial Natural Products and BiosynthesisSynthesis of β-Lactam Compounds

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Naturally-occurring beta-lactamase inhibitors with antibacterial activity

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BROWN, A. G., BUTTERWORTH, D., COLE, M., HANSCOMB, G., HOOD, J. D., READING, C., ROLINSON, G. N.·1976·The Journal of Antibiotics

DOI 10.7164/antibiotics.29.668

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Clavulanic acid, a novel β-lactam isolated from Streptomyces clavuligerus; X-ray crystal structure analysis
Howarth, T. T., BROWN, A. G., & King, T. J. (1976) · Journal of the Chemical Society Chemical Communications · doi:10.1039/c3976000266b · Cited by 162
Self-citation
STUDIES ON PENICILLINASE INHIBITORS PRODUCED BY MICROORGANISMS
Hata, T., Ōmura, S., IWAI, Y., Ohno, H., Takeshima, H., & YAMAGUCHI, N. (1972) · The Journal of Antibiotics · doi:10.7164/antibiotics.25.473 · Cited by 28

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HOWARTH, T. T.; A. G. BROWN & T. J. KING: Clavulanic acid, a novel (3-lactam antibiotic isolated from Streptomyces clavuligerus. J.C.S. Chem. Comm. 1976 in press
MIYAMURA, S. & H. OCHIAI: Inhibitors of 9- lactamases from Gram-negative bacilli. Proc. 8th Internat. Congr. Chemotherapy, Athens. pp. 218~223, 1973

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Authors: BROWN, A. G., BUTTERWORTH, D., COLE, M., HANSCOMB, G., HOOD, J. D., READING, C., & ROLINSON, G. N.
ORCID: BROWN, A. G.
Venue: The Journal of Antibiotics
Publisher: Japan Antibiotics Research Association
Published: 1976
Volume: 29
Issue: 6
Pages: 668-669
ISSN: 0021-8820 (ISSN-L)
1881-1469
DOI: 10.7164/antibiotics.29.668
OpenAlex: W2000168862
Cited by: 399
References: 2
Citations by year: 2026: 7 · 2025: 9 · 2024: 3 · 2023: 8 · 2022: 6 · 2021: 9 · 2020: 5 · 2019: 13 · 2018: 7 · 2017: 6 · 2016: 7 · 2015: 8 · 2014: 8 · 2013: 6 · 2012: 7
FWCI: 3.87
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: The Journal of Antibiotics (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Microbial Natural Products and Biosynthesis
Physical Sciences › Chemistry › Organic Chemistry › Synthesis of β-Lactam Compounds
Keywords: beta-lactamase inhibitors, natural products, antibacterial activity, beta-lactam antibiotics, enzyme inhibition
MeSH terms: Amidohydrolases, Anti-Bacterial Agents, Bacteria, Enterobacteriaceae, Streptomyces, beta-Lactams, beta-Lactamase Inhibitors

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Naturally-occurring beta-lactamase inhibitors with antibacterial activity

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