Williams, Robert W.

Mitonuclear protein imbalance as a conserved longevity mechanism

Houtkooper, R. H., Mouchiroud, L., Ryu, D., Moullan, N., Katsyuba, E., Knott, G., Williams, R. W., & Auwerx, J. (2013) · Nature

Genetics, Aging, and Longevity in Model OrganismsMitochondrial Function and Pathology

Cited by 1,035

Common genetic variants influence human subcortical brain structures

Initiative, T. A. D. N., Hibar, D. P., The CHARGE Consortium, EPIGEN, IMAGEN, SYS, Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., et al. (2015) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 858

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

Quirós, P. M., Prado, M. A., Zamboni, N., D’Amico, D., Williams, R. W., Finley, D., Gygi, S. P., & Auwerx, J. (2017) · Journal of Cell Biology

Endoplasmic Reticulum Stress and DiseaseMitochondrial Function and Pathology

Cited by 832

Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

Chesler, E. J., Lu, L., Shou, S., Qu, Y., Gu, J., Wang, J., Hsu, H. C., Mountz, J. D., Baldwin, N. E., Langston, M. A., et al. (2005) · Nature Genetics

Genetic Mapping and Diversity in Plants and AnimalsGenetic Associations and Epidemiology

Cited by 719

The Control of Neuron Number

Williams, R. W., & Herrup, K. (1988) · Annual Review of Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 585

Building pangenome graphs

Garrison, E., Guarracino, A., Heumos, S., Villani, F., Bao, Z., Tattini, L., Hagmann, J., Vorbrugg, S., Marco-Sola, S., Kubica, C., et al. (2024) · Nature Methods

Genomics and Phylogenetic StudiesGenome Rearrangement Algorithms

Cited by 277

Strain Differences in Stress Responsivity Are Associated with Divergent Amygdala Gene Expression and Glutamate-Mediated Neuronal Excitability

Mozhui, K., Karlsson, R.-M., Kash, T. L., Ihne, J., Norcross, M., Patel, S., Farrell, M. R., Hill, E. E., Graybeal, C., Martin, K. P., et al. (2010) · The Journal of Neuroscience

Stress Responses and CortisolNeuroscience and Neuropharmacology Research

Cited by 226

Metabolic networks of longevity

Houtkooper, R. H., Williams, R. W., & Auwerx, J. (2010) · Cell

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 217

Reproducibility and replicability of rodent phenotyping in preclinical studies

Kafkafi, N., Agassi, J., Chesler, E. J., Crabbe, J. C., Crusio, W. E., Eilam, D., Gerlai, R., Golani, I., Gomez-Marin, A., Heller, R., et al. (2018) · Neuroscience & Biobehavioral Reviews

Animal testing and alternativesResearch Data Management Practices

Cited by 215

A novel cytoarchitectonic area induced experimentally within the primate visual cortex.

Rakic, P., Suñer, I., & Williams, R. W. (1991) · Proceedings of the National Academy of Sciences

Visual perception and processing mechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 208

A platform for experimental precision medicine: The extended BXD mouse family

Ashbrook, D. G., Arends, D., Prins, P., Mulligan, M. K., Roy, S., Williams, E. G., Lutz, C. M., Valenzuela, A., Bohl, C. J., Ingels, J. F., et al. (2021) · Cell Systems

Genetic Mapping and Diversity in Plants and AnimalsGenetic Associations and Epidemiology

Cited by 171

Variation in mouse basolateral amygdala volume is associated with differences in stress reactivity and fear learning

Yang, R. J., Mozhui, K., Karlsson, R.-M., Cameron, H. A., Williams, R. W., & Holmes, A. (2008) · Neuropsychopharmacology

Memory and Neural MechanismsStress Responses and Cortisol

Cited by 143

DNA methylation networks underlying mammalian traits

Haghani, A., Li, C. Z., Robeck, T. R., Zhang, J., Lu, A. T., Ablaeva, J., Acosta-Rodríguez, V. A., Adams, D. M., Alagaili, A. N., Almunia, J., et al. (2023) · Science

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 128

Elimination of neurons from the rhesus monkey's lateral geniculate nucleus during development

Williams, R. W., & Rakic, P. (1988) · Journal of Comparative Neurology

Neurogenesis and neuroplasticity mechanismsVisual perception and processing mechanisms

Cited by 124

Genetic architecture supports mosaic brain evolution and independent brain-body size regulation

Hager, R., Lu, L., Rosen, G. D., & Williams, R. W. (2012) · Nature Communications

Morphological variations and asymmetryAnimal Behavior and Reproduction

Cited by 108

Functionally Enigmatic Genes: A Case Study of the Brain Ignorome

Pandey, A. K., Lu, L., Wang, X., Homayouni, R., & Williams, R. W. (2014) · PLoS ONE

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 90

A natural mutator allele shapes mutation spectrum variation in mice

Sasani, T. A., Ashbrook, D. G., Beichman, A. C., Lu, L., Palmer, A. A., Williams, R. W., Pritchard, J. K., & Harris, K. (2022) · Nature

DNA Repair MechanismsEvolution and Genetic Dynamics

Cited by 64

IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy

Pan, L., Cho, K.-S., Wei, X., Xu, F., Lennikov, A., Hu, G., Tang, J., Guo, S., Chen, J., Kriukov, E., et al. (2023) · Cell Reports

Neuroinflammation and Neurodegeneration MechanismsGlaucoma and retinal disorders

Cited by 52

Genetic Control of Interconnected Neuronal Populations in the Mouse Primary Visual System

Seecharan, D. J., Kulkarni, A. L., Lu, L., Rosen, G. D., & Williams, R. W. (2003) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsRetinal Development and Disorders

Cited by 43

Genetic variation of the cutaneous HPA axis: an analysis of UVB-induced differential responses

Skobowiat, C., Nejati, R., Lu, L., Williams, R. W., & Slominski, A. T. (2013) · Gene

Stress Responses and CortisolSkin Protection and Aging

Cited by 42

The Duke Mouse Brain Atlas: MRI and light sheet microscopy stereotaxic atlas of the mouse brain

Mansour, H., Azrak, R., Cook, J. J., Hornburg, K. J., Qi, Y., Tian, Y., Williams, R. W., Yeh, F.-C., White, L. E., & Johnson, G. A. (2025) · Science Advances

Advanced Neuroimaging Techniques and ApplicationsFunctional Brain Connectivity Studies

Cited by 11

A rapid workflow for neuron counting in combined light sheet microscopy and magnetic resonance histology

Tian, Y., Johnson, G. A., Williams, R. W., & White, L. E. (2023) · Frontiers in Neuroscience

Cell Image Analysis TechniquesMedical Image Segmentation Techniques

Cited by 9

Differing susceptibility of C57BL/6J and DBA/2J mice-parents of the murine BXD family, to severe acute respiratory syndrome coronavirus infection

Li, K., Shen, Y., Miller, M. A., Stabenow, J., Williams, R. W., & Lu, L. (2021) · Cell & Bioscience

SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies

Cited by 9