Simpson, Stephen J.

Lifespan and reproduction in Drosophila : New insights from nutritional geometry

Lee, K. P., Simpson, S. J., Clissold, F. J., Brooks, R., Ballard, J. W. O., Taylor, P. W., Soran, N., & Raubenheimer, D. (2008) · Proceedings of the National Academy of Sciences

Genetics, Aging, and Longevity in Model OrganismsNeurobiology and Insect Physiology Research

Cited by 1,032

The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

Solon-Biet, S. M., McMahon, A. C., Ballard, J. W. O., Ruohonen, K., Wu, L. E., Cogger, V. C., Warren, A., Huang, X., Pichaud, N., Melvin, R. G., et al. (2014) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 904

Obesity: the protein leverage hypothesis

Simpson, S. J., & Raubenheimer, D. (2005) · Obesity Reviews

Regulation of Appetite and ObesityObesity, Physical Activity, Diet

Cited by 591

Optimal foraging when regulating intake of multiple nutrients

Simpson, S. J., Sibly, R. M., Lee, K. P., Behmer, S. T., & Raubenheimer, D. (2004) · Animal Behaviour

Insect-Plant Interactions and ControlAnimal Behavior and Reproduction

Cited by 532

Integrative models of nutrient balancing: application to insects and vertebrates

Raubenheimer, D., & Simpson, S. J. (1997) · Nutrition Research Reviews

Animal Nutrition and PhysiologyRuminant Nutrition and Digestive Physiology

Cited by 454

Macronutrient balance, reproductive function, and lifespan in aging mice

Solon-Biet, S. M., Walters, K. A., Simanainen, U. K., McMahon, A. C., Ruohonen, K., Ballard, J. W. O., Raubenheimer, D., Handelsman, D. J., Le Couteur, D. G., & Simpson, S. J. (2015) · Proceedings of the National Academy of Sciences

Genetics, Aging, and Longevity in Model OrganismsAnimal Behavior and Reproduction

Cited by 243

FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism

Hill, C. M., Laeger, T., Dehner, M., Albarado, D. C., Clarke, B., Wanders, D., Burke, S. J., Collier, J. J., Qualls-Creekmore, E., Solon-Biet, S. M., et al. (2019) · Cell Reports

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 229

The Multidimensional Nutritional Niche

Machovsky-Capuska, G. E., Senior, A. M., Simpson, S. J., & Raubenheimer, D. (2016) · Trends in Ecology & Evolution

Isotope Analysis in EcologyEcology and Vegetation Dynamics Studies

Cited by 219

Protein‐leverage in Mice: The Geometry of Macronutrient Balancing and Consequences for Fat Deposition

Sørensen, A., Mayntz, D., Raubenheimer, D., & Simpson, S. J. (2008) · Obesity

Regulation of Appetite and ObesityNutrition, Health and Food Behavior

Cited by 218

Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework

Solon-Biet, S. M., Cogger, V. C., Pulpitel, T., Heblinski, M., Wahl, D., McMahon, A. C., Warren, A., Durrant-Whyte, J., Walters, K. A., Krycer, J. R., et al. (2016) · Cell Metabolism

Fibroblast Growth Factor ResearchDietary Effects on Health

Cited by 212

The impact of low-protein high-carbohydrate diets on aging and lifespan

Le Couteur, D. G., Solon-Biet, S., Cogger, V. C., Mitchell, S. J., Senior, A., de Cabo, R., Raubenheimer, D., & Simpson, S. J. (2016) · Cellular and Molecular Life Sciences

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 209

Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice

Solon-Biet, S. M., Mitchell, S. J., Coogan, S. C. P., Cogger, V. C., Gokarn, R., McMahon, A. C., Raubenheimer, D., de Cabo, R., Simpson, S. J., & Le Couteur, D. G. (2015) · Cell Reports

Dietary Effects on HealthGenetics, Aging, and Longevity in Model Organisms

Cited by 207

Protein leverage and energy intake

Gosby, A. K., Conigrave, A. D., Raubenheimer, D., & Simpson, S. J. (2014) · Obesity Reviews

Regulation of Appetite and ObesityNutrition, Health and Food Behavior

Cited by 196

Diet-Microbiome Interactions in Health Are Controlled by Intestinal Nitrogen Source Constraints

Holmes, A. J., Chew, Y. V., Colakoglu, F., Cliff, J. B., Klaassens, E., Read, M. N., Solon-Biet, S. M., McMahon, A. C., Cogger, V. C., Ruohonen, K., et al. (2017) · Cell Metabolism

Gut microbiota and healthNutritional Studies and Diet

Cited by 183

Dietary protein, aging and nutritional geometry

Simpson, S. J., Le Couteur, D. G., Raubenheimer, D., Solon-Biet, S. M., Cooney, G. J., Cogger, V. C., & Fontana, L. (2017) · Ageing Research Reviews

Genetics, Aging, and Longevity in Model OrganismsDietary Effects on Health

Cited by 169

Geometric analysis of macronutrient selection in the adult domestic cat, Felis catus

Hewson-Hughes, A. K., Hewson-Hughes, V. L., Miller, A. T., Hall, S. R., Simpson, S. J., & Raubenheimer, D. (2011) · Journal of Experimental Biology

Veterinary Medicine and SurgeryAnimal Nutrition and Physiology

Cited by 161

Protein Leverage: Theoretical Foundations and Ten Points of Clarification

Raubenheimer, D., & Simpson, S. J. (2019) · Obesity

Regulation of Appetite and ObesityNutrition, Health and Food Behavior

Cited by 157

Ultra-processed foods, protein leverage and energy intake in the USA

Martínez Steele, E., Raubenheimer, D., Simpson, S. J., Baraldi, L. G., & Monteiro, C. A. (2018) · Public Health Nutrition

Consumer Attitudes and Food LabelingNutrition, Health and Food Behavior

Cited by 144

Geometric analysis of macronutrient selection in the rat

SIMPSON, S. J., & RAUBENHEIMER, D. (1997) · Appetite

Regulation of Appetite and ObesityAnimal Nutrition and Physiology

Cited by 110

Behavioral Microbiomics: A Multi-Dimensional Approach to Microbial Influence on Behavior

Wong, A. C.-N., Holmes, A., Ponton, F., Lihoreau, M., Wilson, K., Raubenheimer, D., & Simpson, S. J. (2015) · Frontiers in Microbiology

Gut microbiota and healthAnimal Behavior and Reproduction

Cited by 61

Raised FGF-21 and triglycerides accompany increased energy intake driven by protein leverage in lean, healthy individuals: a randomised trial

Gosby, A. K., Lau, N. S., Tam, C. S., Iglesias, M. A., Morrison, C. D., Caterson, I. D., Brand-Miller, J., Conigrave, A. D., Raubenheimer, D., & Simpson, S. J. (2016) · PLoS ONE

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 51

Testing the Protein Leverage Hypothesis in a free-living human population

Martinez-Cordero, C., Kuzawa, C. W., Sloboda, D. M., Stewart, J., Simpson, S. J., & Raubenheimer, D. (2012) · Appetite

Regulation of Appetite and ObesityNutrition, Health and Food Behavior

Cited by 50

Three hundred and fifty generations of extreme food specialisation: testing predictions of nutritional ecology

Warbrick‐Smith, J., Raubenheimer, D., Simpson, S. J., & Behmer, S. T. (2009) · Entomologia Experimentalis et Applicata

Insect-Plant Interactions and ControlPhysiological and biochemical adaptations

Cited by 45

Macronutritional consequences of food generalism in an invasive mammal, the wild boar

Senior, A. M., Grueber, C. E., Machovsky-Capuska, G., Simpson, S. J., & Raubenheimer, D. (2016) · Mammalian Biology

Animal Ecology and Behavior StudiesWildlife Ecology and Conservation

Cited by 36