Boone, Charles

The Genetic Landscape of a Cell

Costanzo, M., Baryshnikova, A., Bellay, J., Kim, Y., Spear, E. D., Sevier, C. S., Ding, H., Koh, J. L. Y., Toufighi, K., Mostafavi, S., et al. (2010) · Science

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 2,162

Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants

Tong, A. H. Y., Evangelista, M., Parsons, A. B., Xu, H., Bader, G. D., Pagé, N., Robinson, M., Raghibizadeh, S., Hogue, C. W. V., Bussey, H., et al. (2001) · Science

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 2,138

A global genetic interaction network maps a wiring diagram of cellular function

Costanzo, M., VanderSluis, B., Koch, E. N., Baryshnikova, A., Pons, C., Tan, G., Wang, W., Usaj, M., Hanchard, J., Lee, S. D., et al. (2016) · Science

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 1,240

Exploration of the Function and Organization of the Yeast Early Secretory Pathway through an Epistatic Miniarray Profile

Schuldiner, M., Collins, S. R., Thompson, N. J., Denic, V., Bhamidipati, A., Punna, T., Ihmels, J., Andrews, B., Boone, C., Greenblatt, J. F., et al. (2005) · Cell

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 870

Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

Collins, S. R., Miller, K. M., Maas, N. L., Roguev, A., Fillingham, J., Chu, C. S., Schuldiner, M., Gebbia, M., Recht, J., Shales, M., et al. (2007) · Nature

Genomics and Chromatin DynamicsFungal and yeast genetics research

Cited by 869

Navigating the Chaperone Network: An Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone

Zhao, R., Davey, M., Hsu, Y.-C., Kaplanek, P., Tong, A., Parsons, A. B., Krogan, N., Cagney, G., Mai, D., Greenblatt, J., et al. (2005) · Cell

Heat shock proteins researchFungal and yeast genetics research

Cited by 819

Exploring genetic interactions and networks with yeast

Boone, C., Bussey, H., & Andrews, B. J. (2007) · Nature Reviews Genetics

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 661

Exploration of Essential Gene Functions via Titratable Promoter Alleles

Mnaimneh, S., Davierwala, A. P., Haynes, J., Moffat, J., Peng, W.-T., Zhang, W., Yang, X., Pootoolal, J., Chua, G., Lopez, A., et al. (2004) · Cell

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 604

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens

Hart, T., Tong, A. H. Y., Chan, K., Van Leeuwen, J., Seetharaman, A., Aregger, M., Chandrashekhar, M., Hustedt, N., Seth, S., Noonan, A., et al. (2017) · G3 Genes|Genomes|Genetics

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 599

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

Yang, X., Coulombe-Huntington, J., Kang, S., Sheynkman, G. M., Hao, T., Richardson, A., Sun, S., Yang, F., Shen, Y. A., Murray, R. R., et al. (2016) · Cell

RNA Research and SplicingBioinformatics and Genomic Networks

Cited by 583

A Specificity Map for the PDZ Domain Family

Tonikian, R., Zhang, Y., Sazinsky, S. L., Currell, B., Yeh, J.-H., Reva, B., Held, H. A., Appleton, B. A., Evangelista, M., Wu, Y., et al. (2008) · PLoS Biology

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 476

Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

Baryshnikova, A., Costanzo, M., Kim, Y., Ding, H., Koh, J., Toufighi, K., Youn, J.-Y., Ou, J., San Luis, B.-J., Bandyopadhyay, S., et al. (2010) · Nature Methods

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 364

Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae

Reguly, T., Breitkreutz, A., Boucher, L., Breitkreutz, B.-J., Hon, G. C., Myers, C. L., Parsons, A., Friesen, H., Oughtred, R., Tong, A., et al. (2006) · Journal of Biology

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 326

Yeast Proteome Dynamics from Single Cell Imaging and Automated Analysis

Chong, Y. T., Koh, J. L. Y., Friesen, H., Kaluarachchi Duffy, S., Cox, M. J., Moses, A., Moffat, J., Boone, C., & Andrews, B. J. (2015) · Cell

Advanced Fluorescence Microscopy TechniquesAdvanced Proteomics Techniques and Applications

Cited by 274

eSGA: E. coli synthetic genetic array analysis

Butland, G., Babu, M., Díaz-Mejía, J. J., Bohdana, F., Phanse, S., Gold, B., Yang, W., Li, J., Gagarinova, A. G., Pogoutse, O., et al. (2008) · Nature Methods

Bacterial Genetics and BiotechnologyMicrobial Metabolic Engineering and Bioproduction

Cited by 256

Combining biological networks to predict genetic interactions

Wong, S. L., Zhang, L. V., Tong, A. H. Y., Li, Z., Goldberg, D. S., King, O. D., Lesage, G., Vidal, M., Andrews, B., Bussey, H., et al. (2004) · Proceedings of the National Academy of Sciences

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 245

Global Genetic Networks and the Genotype-to-Phenotype Relationship

Costanzo, M., Kuzmin, E., van Leeuwen, J., Mair, B., Moffat, J., Boone, C., & Andrews, B. (2019) · Cell

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 241

The interaction network of the chaperonin CCT

Dekker, C., Stirling, P. C., McCormack, E. A., Filmore, H., Paul, A., Brost, R. L., Costanzo, M., Boone, C., Leroux, M. R., & Willison, K. R. (2008) · The EMBO Journal

Heat shock proteins researchMicrotubule and mitosis dynamics

Cited by 220

Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

Dixon, S. J., Fedyshyn, Y., Koh, J. L. Y., Prasad, T. S. K., Chahwan, C., Chua, G., Toufighi, K., Baryshnikova, A., Hayles, J., Hoe, K.-L., et al. (2008) · Proceedings of the National Academy of Sciences

Fungal and yeast genetics researchBioinformatics and Genomic Networks

Cited by 205

Systems-level antimicrobial drug and drug synergy discovery

Roemer, T., & Boone, C. (2013) · Nature Chemical Biology

Computational Drug Discovery MethodsMicrobial Natural Products and Biosynthesis

Cited by 159

Mode of Selection and Experimental Evolution of Antifungal Drug Resistance in Saccharomyces cerevisiae

Anderson, J. B., Sirjusingh, C., Parsons, A. B., Boone, C., Wickens, C., Cowen, L. E., & Kohn, L. M. (2003) · Genetics

Evolution and Genetic DynamicsFungal and yeast genetics research

Cited by 156

Genetic interactions reveal the evolutionary trajectories of duplicate genes

VanderSluis, B., Bellay, J., Musso, G., Costanzo, M., Papp, B., Vizeacoumar, F. J., Baryshnikova, A., Andrews, B., Boone, C., & Myers, C. L. (2010) · Molecular Systems Biology

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 110

Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell

Magtanong, L., Ho, C. H., Barker, S. L., Jiao, W., Baryshnikova, A., Bahr, S., Smith, A. M., Heisler, L. E., Choy, J. S., Kuzmin, E., et al. (2011) · Nature Biotechnology

Bioinformatics and Genomic NetworksFungal and yeast genetics research

Cited by 108

CYCLoPs: A Comprehensive Database Constructed from Automated Analysis of Protein Abundance and Subcellular Localization Patterns in Saccharomyces cerevisiae

Koh, J. L. Y., Chong, Y. T., Friesen, H., Moses, A., Boone, C., Andrews, B. J., & Moffat, J. (2015) · G3 Genes|Genomes|Genetics

Cell Image Analysis TechniquesFungal and yeast genetics research

Cited by 80