Clarke, Iain J.

Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B

Goodman, R. L., Lehman, M. N., Smith, J. T., Coolen, L. M., de Oliveira, C. V. R., Jafarzadehshirazi, M. R., Pereira, A., Iqbal, J., Caraty, A., Ciofi, P., et al. (2007) · Endocrinology

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 692

KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season

Smith, J. T., Clay, C. M., Caraty, A., & Clarke, I. J. (2007) · Endocrinology

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 404

Variation in Kisspeptin and RFamide-Related Peptide (RFRP) Expression and Terminal Connections to Gonadotropin-Releasing Hormone Neurons in the Brain: A Novel Medium for Seasonal Breeding in the Sheep

Smith, J. T., Coolen, L. M., Kriegsfeld, L. J., Sari, I. P., Jaafarzadehshirazi, M. R., Maltby, M., Bateman, K., Goodman, R. L., Tilbrook, A. J., Ubuka, T., et al. (2008) · Endocrinology

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 387

Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation

Roseweir, A. K., Kauffman, A. S., Smith, J. T., Guerriero, K. A., Morgan, K., Pielecka-Fortuna, J., Pineda, R., Gottsch, M. L., Tena-Sempere, M., Moenter, S. M., et al. (2009) · The Journal of Neuroscience

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 379

Kisspeptin synchronizes preovulatory surges in cyclical ewes and causes ovulation in seasonally acyclic ewes

Caraty, A., Smith, J. T., Lomet, D., Ben Saïd, S., Morrissey, A., Cognie, J., Doughton, B., Baril, G., Briant, C., & Clarke, I. J. (2007) · Endocrinology

Hypothalamic control of reproductive hormonesReproductive Physiology in Livestock

Cited by 313

Studies of the Secretion of Corticotropin-Releasing Factor and Arginine Vasopressin into the Hypophysial-Portal Circulation of the Conscious Sheep

Engler, D., Pham, T., Fullerton, M. J., Ooi, G., Funder, J. W., & Clarke, I. J. (2008) · Neuroendocrinology

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 235

Measurement of growth hormone–releasing hormone and somatostatin in hypothalamic–portal plasma of unanesthetized sheep. spontaneous secretion and response to insulin–induced hypoglycemia

Frohman, L. A., Downs, T. R., Clarke, I. J., & Thomas, G. B. (1990) · Journal of Clinical Investigation

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 178

Stress, cortisol, and obesity: A role for cortisol responsiveness in identifying individuals prone to obesity

Hewagalamulage, S. D., Lee, T. K., Clarke, I. J., & Henry, B. A. (2016) · Domestic Animal Endocrinology

Regulation of Appetite and ObesityStress Responses and Cortisol

Cited by 167

Effects on Plasma Luteinizing Hormone and Follicle-Stimulating Hormone of Varying the Frequency and Amplitude of Gonadotropin-Releasing Hormone Pulses in Ovariectomized Ewes with Hypothalamo-Pituitary Disconnection

Clarke, I. J., Cummins, J. T., Findlay, J. K., Burman, K. J., & Doughton, B. W. (2008) · Neuroendocrinology

Hypothalamic control of reproductive hormonesGrowth Hormone and Insulin-like Growth Factors

Cited by 122

Cortisol Reduces Gonadotropin-Releasing Hormone Pulse Frequency in Follicular Phase Ewes: Influence of Ovarian Steroids

Oakley, A. E., Breen, K. M., Clarke, I. J., Karsch, F. J., Wagenmaker, E. R., & Tilbrook, A. J. (2009) · Endocrinology

Hypothalamic control of reproductive hormonesReproductive Physiology in Livestock

Cited by 120

Kisspeptin and seasonality in sheep

Clarke, I. J., Smith, J. T., Caraty, A., Goodman, R. L., & Lehman, M. N. (2009) · Peptides

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 96

Studies of the secretion of corticotropin-releasing factor and arginine vasopressin into the hypophysial-portal circulation of the conscious sheep: II. The central noradrenergic and neuropeptide Y pathways cause immediate and prolonged hypothalamic-pituitary-adrenal activation. Potential involvement in the pseudo-Cushing’s syndrome of endogenous depression and anorexia nervosa

Liu, J. P., Clarke, I. J., Funder, J. W., & Engler, D. (1994) · Journal of Clinical Investigation

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 81

Reconstruction of in vivo time-evolving neuroendocrine dose–response properties unveils admixed deterministic and stochastic elements

Keenan, D. M., Alexander, S., Irvine, C. H. G., Clarke, I., Scott, C., Turner, A., Tilbrook, A. J., Canny, B. J., & Veldhuis, J. D. (2004) · Proceedings of the National Academy of Sciences

Stress Responses and CortisolReceptor Mechanisms and Signaling

Cited by 70

Growth hormone-releasing hormone and somatostatin concentrations in the hypophysial portal blood of conscious sheep during the infusion of growth hormone-releasing peptide-6

Fletcher, T. P., Thomas, G. B., & Clarke, I. J. (1996) · Domestic Animal Endocrinology

Growth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

Cited by 62

Studies of the Regulation of the Hypothalamic-Pituitary-Adrenal Axis in Sheep with Hypothalamic-Pituitary Disconnection. II. Evidence for in Vivo Ultradian Hypersecretion of Proopiomelanocortin Peptides by the Isolated Anterior and Intermediate Pituitary*

ENGLER, D., PHAM, T., LIU, J.-P., FULLERTON, M. J., CLARKE, I. J., & FUNDER, J. W. (1990) · Endocrinology

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 61

GnRH-associated peptide (GAP) is cosecreted with GnRH into the hypophyseal portal blood of ovariectomized sheep

Clarke, I. J., Cummins, J. T., Karsch, F. J., Seeburg, P. H., & Nikolics, K. (1987) · Biochemical and Biophysical Research Communications

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 52

Seasonal and cyclical change in the luteinizing hormone response to kisspeptin in the ewe

Smith, J. T., Saleh, S. N. H., & Clarke, I. J. (2009) · Neuroendocrinology

Hypothalamic control of reproductive hormonesReproductive Physiology in Livestock

Cited by 49

Stress Increases Gonadotropin Inhibitory Hormone Cell Activity and Input to GnRH Cells in Ewes

Clarke, I. J., Bartolini, D., Conductier, G., & Henry, B. A. (2016) · Endocrinology

Hypothalamic control of reproductive hormonesStress Responses and Cortisol

Cited by 45

Effects of vasopressin and elimination of corticotropin–releasing hormone–target cells on pro–opiomelanocortin mRNA levels and adrenocorticotropin secretion in ovine anterior pituitary cells

van de Pavert, S. A., Clarke, I. J., Rao, A., Vrana, K. E., & Schwartz, J. (1997) · Journal of Endocrinology

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 35

Effects of Gonadotropin-Releasing Hormone Pulse-Frequency Modulation on Lutein izing Hormone, Foil icle-Stimu lating Hormone and Testosterone Secretion in H ypothalamo/P ituitary-Disconnected Rams12

Wu, F. C. W., Irby, D. C., Clarke, I. J., Cummins, J. T., & de Kretser, D. M. (1987) · Biology of Reproduction

Hypothalamic control of reproductive hormonesGrowth Hormone and Insulin-like Growth Factors

Cited by 34

The role of noradrenaline in the generation of the preovulatory LH surge in the ewe

Clarke, I. J., Scott, C. J., Pereira, A., & Pompolo, S. (2006) · Domestic Animal Endocrinology

Hypothalamic control of reproductive hormonesReproductive Physiology in Livestock

Cited by 22

Glucagon-like peptide-1 control of GnRH secretion in female sheep

Arbabi, L., Li, Q., Henry, B. A., & Clarke, I. J. (2021) · Journal of Endocrinology

Hypothalamic control of reproductive hormonesNeuropeptides and Animal Physiology

Cited by 19