Tollenaar, Rob A. E. M.
Leiden University Medical Center
21 papers on CoChatORCID 0000-0002-6831-6082
Most cited papers
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Genome-wide association study identifies novel breast cancer susceptibility loci
Easton, D. F., Pooley, K. A., Dunning, A. M., Pharoah, P. D. P., Thompson, D., Ballinger, D. G., Struewing, J. P., Morrison, J., Field, H., Luben, R., et al. (2007) · Nature
Genetic Associations and EpidemiologyBRCA gene mutations in cancer
Cited by 2,319
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Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
Berman, B. P., Weisenberger, D. J., Aman, J. F., Hinoue, T., Ramjan, Z., Liu, Y., Noushmehr, H., Lange, C. P. E., van Dijk, C. M., Tollenaar, R. A. E. M., et al. (2012) · Nature Genetics
Epigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cited by 660
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The Carcinoma–Stromal Ratio of Colon Carcinoma Is an Independent Factor for Survival Compared to Lymph Node Status and Tumor Stage
Mesker, W. E., Junggeburt, J. M. C., Szuhai, K., de Heer, P., Morreau, H., Tanke, H. J., & Tollenaar, R. A. E. M. (2007) · Analytical Cellular Pathology
Colorectal Cancer Surgical TreatmentsColorectal Cancer Treatments and Studies
Cited by 354
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EMT is the dominant program in human colon cancer
Loboda, A., Nebozhyn, M. V., Watters, J. W., Buser, C. A., Shaw, P. M., Huang, P. S., Van't Veer, L., Tollenaar, R. A., Jackson, D. B., Agrawal, D., et al. (2011) · BMC Medical Genomics
Gene expression and cancer classificationCancer Cells and Metastasis
Cited by 274
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Scoring the tumor-stroma ratio in colon cancer: procedure and recommendations
van Pelt, G. W., Kjær-Frifeldt, S., van Krieken, J. H. J. M., Al Dieri, R., Morreau, H., Tollenaar, R. A. E. M., Sørensen, F. B., & Mesker, W. E. (2018) · Virchows Archiv
Colorectal Cancer Surgical TreatmentsColorectal Cancer Treatments and Studies
Cited by 192
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Age- and Tumor Subtype–Specific Breast Cancer Risk Estimates for CH EK 2 *1100delC Carriers
Schmidt, M. K., Hogervorst, F., van Hien, R., Cornelissen, S., Broeks, A., Adank, M. A., Meijers, H., Waisfisz, Q., Hollestelle, A., Schutte, M., et al. (2016) · Journal of Clinical Oncology
BRCA gene mutations in cancerBreast Lesions and Carcinomas
Cited by 173
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Tamoxifen and Risk of Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers
Phillips, K.-A., Milne, R. L., Rookus, M. A., Daly, M. B., Antoniou, A. C., Peock, S., Frost, D., Easton, D. F., Ellis, S., Friedlander, M. L., et al. (2013) · Journal of Clinical Oncology
BRCA gene mutations in cancerMultiple and Secondary Primary Cancers
Cited by 171
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The tumour–stroma ratio in colon cancer: the biological role and its prognostic impact
van Pelt, G. W., Sandberg, T. P., Morreau, H., Gelderblom, H., van Krieken, J. H. J. M., Tollenaar, R. A. E. M., & Mesker, W. E. (2018) · Histopathology
Cancer Cells and MetastasisColorectal Cancer Treatments and Studies
Cited by 155
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Magnetic Resonance Imaging Surveillance Detects Early-Stage Pancreatic Cancer in Carriers of a p16-Leiden Mutation
Vasen, H. F. A., Wasser, M., van Mil, A., Tollenaar, R. A., Konstantinovski, M., Gruis, N. A., Bergman, W., Hes, F. J., Hommes, D. W., Offerhaus, G. J. A., et al. (2011) · Gastroenterology
Pancreatic and Hepatic Oncology ResearchMRI in cancer diagnosis
Cited by 152
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Efficacy of meaning-centered group psychotherapy for cancer survivors: a randomized controlled trial
van der Spek, N., Vos, J., van Uden-Kraan, C. F., Breitbart, W., Cuijpers, P., Holtmaat, K., Witte, B. I., Tollenaar, R. A. E. M., & Verdonck-de Leeuw, I. M. (2017) · Psychological Medicine
Cancer survivorship and careReligion, Spirituality, and Psychology
Cited by 135
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Increased expression of cancer-associated fibroblast markers at the invasive front and its association with tumor-stroma ratio in colorectal cancer
Sandberg, T. P., Stuart, M. P. M. E., Oosting, J., Tollenaar, R. A. E. M., Sier, C. F. M., & Mesker, W. E. (2019) · BMC Cancer
Cancer Cells and MetastasisPancreatic and Hepatic Oncology Research
Cited by 135
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Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers
van den Broek, A. J., van ’t Veer, L. J., Hooning, M. J., Cornelissen, S., Broeks, A., Rutgers, E. J., Smit, V. T. H. B. M., Cornelisse, C. J., van Beek, M., Janssen-Heijnen, M. L., et al. (2016) · Journal of Clinical Oncology
BRCA gene mutations in cancerMultiple and Secondary Primary Cancers
Cited by 104
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Survival benefit in women with BRCA1 mutation or familial risk in the MRI screening study (MRISC)
Saadatmand, S., Obdeijn, I., Rutgers, E. J., Oosterwijk, J. C., Tollenaar, R. A., Woldringh, G. H., Bergers, E., Verhoef, C., Heijnsdijk, E. A., Hooning, M. J., et al. (2015) · International Journal of Cancer
Digital Radiography and Breast ImagingMRI in cancer diagnosis
Cited by 96
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Body mass index and breast cancer survival: a Mendelian randomization analysis
Guo, Q., Burgess, S., Turman, C., Bolla, M. K., Wang, Q., Lush, M., Abraham, J., Aittomäki, K., Andrulis, I. L., Apicella, C., et al. (2017) · International Journal of Epidemiology
Cancer Risks and FactorsGenetic Associations and Epidemiology
Cited by 64
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Effectiveness and cost-effectiveness of meaning-centered group psychotherapy in cancer survivors: protocol of a randomized controlled trial
van der Spek, N., Vos, J., van Uden-Kraan, C. F., Breitbart, W., Cuijpers, P., Knipscheer-Kuipers, K., Willemsen, V., Tollenaar, R. A., van Asperen, C. J., & Verdonck-de Leeuw, I. M. (2014) · BMC Psychiatry
Cancer survivorship and careChildhood Cancer Survivors' Quality of Life
Cited by 52
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Disorganised stroma determined on pre‐treatment breast cancer biopsies is associated with poor response to neoadjuvant chemotherapy: Results from the NEOZOTAC trial
Dekker, T. J. A., Charehbili, A., Smit, V. T. H. B. M., ten Dijke, P., Meershoek-Klein Kranenbarg, E., van de Velde, C. J. H., Nortier, J. W. R., Tollenaar, R. A. E. M., Mesker, W. E., & Kroep, J. R. (2015) · Molecular Oncology
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 36
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Predictive potential of tumour-stroma ratio on benefit from adjuvant bevacizumab in high-risk stage II and stage III colon cancer
Zunder, S. M., van Pelt, G. W., Gelderblom, H. J., Mancao, C., Putter, H., Tollenaar, R. A., & Mesker, W. E. (2018) · British Journal of Cancer
Colorectal Cancer Treatments and StudiesColorectal Cancer Surgical Treatments
Cited by 36
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Self-supervised learning reveals clinically relevant histomorphological patterns for therapeutic strategies in colon cancer
Liu, B., Polack, M., Coudray, N., Claudio Quiros, A., Sakellaropoulos, T., Le, H., Karimkhan, A., Crobach, A. S. L. P., van Krieken, J. H. J. M., Yuan, K., et al. (2025) · Nature Communications
AI in cancer detectionRadiomics and Machine Learning in Medical Imaging
Cited by 25
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Evaluation of the Dutch BRCA1/2 clinical genetic center referral criteria in an unselected early breast cancer population
van den Broek, A. J., de Ruiter, K., van 't Veer, L. J., Tollenaar, R. A. E. M., van Leeuwen, F. E., Verhoef, S., & Schmidt, M. K. (2015) · European Journal of Human Genetics
BRCA gene mutations in cancerBreast Lesions and Carcinomas
Cited by 18
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Regulatory aspects of genetic research with residual human tissue: Effective and efficient data coding
Schmidt, M. K., Vermeulen, E., Tollenaar, R. A. E. M., Veer, L. J. V., & Leeuwen, F. E. V. (2009) · European Journal of Cancer
Ethics in Clinical ResearchBRCA gene mutations in cancer
Cited by 12
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Stromal organization as predictive biomarker for the treatment of colon cancer with adjuvant bevacizumab; a post-hoc analysis of the AVANT trial
Zunder, S., van der Wilk, P., Gelderblom, H., Dekker, T., Mancao, C., Kiialainen, A., Putter, H., Tollenaar, R., & Mesker, W. (2019) · Cellular Oncology
Colorectal Cancer Treatments and StudiesColorectal Cancer Surgical Treatments
Cited by 9
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