Surmeier, D. James

D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons

Surmeier, D. J., Ding, J., Day, M., Wang, Z., & Shen, W. (2007) · Trends in Neurosciences

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 1,203

Dichotomous dopaminergic control of striatal synaptic plasticity

Shen, W., Flajolet, M., Greengard, P., & Surmeier, D. J. (2008) · Science

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 1,190

A translational profiling approach for the molecular characterization of CNS cell types

Heiman, M., Schaefer, A., Gong, S., Peterson, J. D., Day, M., Ramsey, K. E., Suárez-Fariñas, M., Schwarz, C., Stephan, D. A., Surmeier, D. J., et al. (2008) · Cell

RNA and protein synthesis mechanismsNeuroscience and Neuropharmacology Research

Cited by 1,134

Negative feedback control of neuronal activity by microglia

Badimon, A., Strasburger, H. J., Ayata, P., Chen, X., Nair, A., Ikegami, A., Hwang, P., Chan, A. T., Graves, S. M., Uweru, J. O., et al. (2020) · Nature

Neuroinflammation and Neurodegeneration MechanismsAdenosine and Purinergic Signaling

Cited by 979

Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens

Nicola, S. M., Surmeier, D. J., & Malenka, R. C. (2000) · Annual Review of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 931

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

Burbulla, L. F., Song, P., Mazzulli, J. R., Zampese, E., Wong, Y. C., Jeon, S., Santos, D. P., Blanz, J., Obermaier, C. D., Strojny, C., et al. (2017) · Science

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 874

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

Obeso, J. A., Stamelou, M., Goetz, C. G., Poewe, W., Lang, A. E., Weintraub, D., Burn, D., Halliday, G. M., Bezard, E., Przedborski, S., et al. (2017) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsNeurology and Historical Studies

Cited by 859

Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models

Day, M., Wang, Z., Ding, J., An, X., Ingham, C. A., Shering, A. F., Wokosin, D., Ilijic, E., Sun, Z., Sampson, A. R., et al. (2006) · Nature Neuroscience

Parkinson's Disease Mechanisms and TreatmentsNeuroscience and Neuropharmacology Research

Cited by 745

Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

Kelz, M. B., Chen, J., Carlezon, W. A., Whisler, K., Gilden, L., Beckmann, A. M., Steffen, C., Zhang, Y.-J., Marotti, L., Self, D. W., et al. (1999) · Nature

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 641

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease

Cooper, O., Seo, H., Andrabi, S., Guardia-Laguarta, C., Graziotto, J., Sundberg, M., McLean, J. R., Carrillo-Reid, L., Xie, Z., Osborn, T., et al. (2012) · Science Translational Medicine

Parkinson's Disease Mechanisms and TreatmentsPluripotent Stem Cells Research

Cited by 508

D2Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade

Hernández-López, S., Tkatch, T., Perez-Garci, E., Galarraga, E., Bargas, J., Hamm, H., & Surmeier, D. J. (2000) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 443

Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson’s disease

Taverna, S., Ilijic, E., & Surmeier, D. J. (2008) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchDeep Brain Stimulation and Movement Disorders

Cited by 399

Kalirin-7 Controls Activity-Dependent Structural and Functional Plasticity of Dendritic Spines

Xie, Z., Srivastava, D. P., Photowala, H., Kai, L., Cahill, M. E., Woolfrey, K. M., Shum, C. Y., Surmeier, D. J., & Penzes, P. (2007) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 373

Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor Complex

Schaefer, A., Sampath, S. C., Intrator, A., Min, A., Gertler, T. S., Surmeier, D. J., Tarakhovsky, A., & Greengard, P. (2009) · Neuron

Epigenetics and DNA MethylationGenetics and Neurodevelopmental Disorders

Cited by 317

The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease

Surmeier, D. J., Guzman, J. N., Sanchez-Padilla, J., & Schumacker, P. T. (2011) · Neuroscience

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 236

Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington’s disease

Plotkin, J. L., Day, M., Peterson, J. D., Xie, Z., Kress, G. J., Rafalovich, I., Kondapalli, J., Gertler, T. S., Flajolet, M., Greengard, P., et al. (2014) · Neuron

Genetic Neurodegenerative DiseasesNerve injury and regeneration

Cited by 187

Neuronal vulnerability, pathogenesis, and Parkinson's disease

Sulzer, D., & Surmeier, D. J. (2013) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 184

Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes

Cahill, M. E., Xie, Z., Day, M., Photowala, H., Barbolina, M. V., Miller, C. A., Weiss, C., Radulovic, J., Sweatt, J. D., Disterhoft, J. F., et al. (2009) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 170

Muscarinic modulation of striatal function and circuitry

Goldberg, J. A., Ding, J. B., & Surmeier, D. J. (2012) · Handbook of Experimental Pharmacology

Neuroscience and Neuropharmacology ResearchNicotinic Acetylcholine Receptors Study

Cited by 150

Dopaminergic modulation of striatal function and Parkinson’s disease

Zhai, S., Shen, W., Graves, S. M., & Surmeier, D. J. (2019) · Journal of Neural Transmission

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 100

Calcium-Activated SK Channels Influence Voltage-Gated Ion Channels to Determine the Precision of Firing in Globus Pallidus Neurons

Deister, C. A., Chan, C. S., Surmeier, D. J., & Wilson, C. J. (2009) · Journal of Neuroscience

Ion channel regulation and functionstochastic dynamics and bifurcation

Cited by 85

Calcium, Bioenergetics, and Parkinson’s Disease

Zampese, E., & Surmeier, D. J. (2020) · Cells

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

Cited by 79

The pathology roadmap in Parkinson disease

Surmeier, D. J., & Sulzer, D. (2013) · Prion

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 74

Defects in mRNA Translation in LRRK2-Mutant hiPSC-Derived Dopaminergic Neurons Lead to Dysregulated Calcium Homeostasis

Kim, J. W., Yin, X., Jhaldiyal, A., Khan, M. R., Martin, I., Xie, Z., Perez-Rosello, T., Kumar, M., Abalde-Atristain, L., Xu, J., et al. (2020) · Cell Stem Cell

Parkinson's Disease Mechanisms and TreatmentsRNA and protein synthesis mechanisms

Cited by 56