Ganz, Tomas

Hepcidin Regulates Cellular Iron Efflux by Binding to Ferroportin and Inducing Its Internalization

Nemeth, E., Tuttle, M. S., Powelson, J., Vaughn, M. B., Donovan, A., Ward, D. M., Ganz, T., & Kaplan, J. (2004) · Science

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 4,803

Defensins: antimicrobial peptides of innate immunity

Ganz, T. (2003) · Nature Reviews Immunology

Antimicrobial Peptides and ActivitiesInvertebrate Immune Response Mechanisms

Cited by 3,066

IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

Nemeth, E., Rivera, S., Gabayan, V., Keller, C., Taudorf, S., Pedersen, B. K., & Ganz, T. (2004) · Journal of Clinical Investigation

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 2,650

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

Park, C. H., Valore, E. V., Waring, A. J., & Ganz, T. (2001) · Journal of Biological Chemistry

Antimicrobial Peptides and ActivitiesIron Metabolism and Disorders

Cited by 2,168

Endogenous Antimicrobial Peptides and Skin Infections in Atopic Dermatitis

Ong, P. Y., Ohtake, T., Brandt, C., Strickland, I., Boguniewicz, M., Ganz, T., Gallo, R. L., & Leung, D. Y. M. (2002) · New England Journal of Medicine

Antimicrobial Peptides and ActivitiesDermatology and Skin Diseases

Cited by 1,960

Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation

Ganz, T. (2003) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 1,544

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

Nemeth, E., Valore, E. V., Territo, M., Schiller, G., Lichtenstein, A., & Ganz, T. (2003) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 1,417

Hepcidin and iron homeostasis

Ganz, T., & Nemeth, E. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 1,282

Anemia of inflammation

Weiss, G., Ganz, T., & Goodnough, L. T. (2019) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 1,219

Identification of erythroferrone as an erythroid regulator of iron metabolism

Kautz, L., Jung, G., Valore, E. V., Rivella, S., Nemeth, E., & Ganz, T. (2014) · Nature Genetics

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 1,127

Systemic Iron Homeostasis

Ganz, T. (2013) · Physiological Reviews

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 1,122

Mutations in HFE2 cause iron overload in chromosome 1q–linked juvenile hemochromatosis

Papanikolaou, G., Samuels, M. E., Ludwig, E. H., MacDonald, M. L. E., Franchini, P. L., Dubé, M.-P., Andres, L., MacFarlane, J., Sakellaropoulos, N., Politou, M., et al. (2004) · Nature Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 974

Hepcidin and iron regulation, 10 years later

Ganz, T. (2011) · Blood

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 962

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

Tanno, T., Bhanu, N. V., Oneal, P. A., Goh, S.-H., Staker, P., Lee, Y. T., Moroney, J. W., Reed, C. H., Luban, N. L., Wang, R.-H., et al. (2007) · Nature Medicine

Iron Metabolism and DisordersHemoglobinopathies and Related Disorders

Cited by 854

Iron homeostasis in host defence and inflammation

Ganz, T., & Nemeth, E. (2015) · Nature Reviews Immunology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 843

Regulation of Iron Metabolism by Hepcidin

Nemeth, E., & Ganz, T. (2006) · Annual Review of Nutrition

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 756

Immunoassay for human serum hepcidin

Ganz, T., Olbina, G., Girelli, D., Nemeth, E., & Westerman, M. (2008) · Blood

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 688

Ironing out Ferroportin

Drakesmith, H., Nemeth, E., & Ganz, T. (2015) · Cell Metabolism

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 638

The Role of Hepcidin in Iron Metabolism

Nemeth, E., & Ganz, T. (2009) · Acta Haematologica

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 607

Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response

Liuzzi, J. P., Lichten, L. A., Rivera, S., Blanchard, R. K., Aydemir, T. B., Knutson, M. D., Ganz, T., & Cousins, R. J. (2005) · Proceedings of the National Academy of Sciences

Trace Elements in HealthIron Metabolism and Disorders

Cited by 594

Anemia of Inflammation

Ganz, T. (2019) · New England Journal of Medicine

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 589

Hepcidin-Ferroportin Interaction Controls Systemic Iron Homeostasis

Nemeth, E., & Ganz, T. (2021) · International Journal of Molecular Sciences

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 540

Suppression of hepcidin during anemia requires erythropoietic activity

Pak, M., Lopez, M. A., Gabayan, V., Ganz, T., & Rivera, S. (2006) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 472

Hepcidin and disorders of iron metabolism

Ganz, T., & Nemeth, E. (2011) · Annual Review of Medicine

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 466