Siegelbaum, Steven A.

The hippocampal CA2 region is essential for social memory

Hitti, F. L., & Siegelbaum, S. A. (2014) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 976

Molecular and Functional Heterogeneity of Hyperpolarization-Activated Pacemaker Channels in the Mouse CNS

Santoro, B., Chen, S., Lüthi, A., Pavlidis, P., Shumyatsky, G. P., Tibbs, G. R., & Siegelbaum, S. A. (2000) · The Journal of Neuroscience

Ion channel regulation and functionCardiac electrophysiology and arrhythmias

Cited by 600

Synapses and Memory Storage

Mayford, M., Siegelbaum, S. A., & Kandel, E. R. (2012) · Cold Spring Harbor Perspectives in Biology

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 500

Properties of Hyperpolarization-Activated Pacemaker Current Defined by Coassembly of Hcn1 and Hcn2 Subunits and Basal Modulation by Cyclic Nucleotide

Chen, S., Wang, J., & Siegelbaum, S. A. (2001) · The Journal of General Physiology

Ion channel regulation and functionCardiac electrophysiology and arrhythmias

Cited by 416

Presynaptic BDNF Required for a Presynaptic but Not Postsynaptic Component of LTP at Hippocampal CA1-CA3 Synapses

Zakharenko, S. S., Patterson, S. L., Dragatsis, I., Zeitlin, S. O., Siegelbaum, S. A., Kandel, E. R., & Morozov, A. (2003) · Neuron

Neuroscience and Neuropharmacology ResearchNerve injury and regeneration

Cited by 334

Strong CA2 Pyramidal Neuron Synapses Define a Powerful Disynaptic Cortico-Hippocampal Loop

Chevaleyre, V., & Siegelbaum, S. A. (2010) · Neuron

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 324

A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics

Meira, T., Leroy, F., Buss, E. W., Oliva, A., Park, J., & Siegelbaum, S. A. (2018) · Nature Communications

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 310

Visualization of changes in presynaptic function during long-term synaptic plasticity

Zakharenko, S. S., Zablow, L., & Siegelbaum, S. A. (2001) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 305

Gating of hippocampal activity, plasticity, and memory by entorhinal cortex long-range inhibition

Basu, J., Zaremba, J. D., Cheung, S. K., Hitti, F. L., Zemelman, B. V., Losonczy, A., & Siegelbaum, S. A. (2016) · Science

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 274

Hippocampal CA2 sharp-wave ripples reactivate and promote social memory

Oliva, A., Fernández-Ruiz, A., Leroy, F., & Siegelbaum, S. A. (2020) · Nature

Memory and Neural MechanismsSleep and Wakefulness Research

Cited by 268

Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release

McMahon, H. T., Bolshakov, V. Y., Janz, R., Hammer, R. E., Siegelbaum, S. A., & Südhof, T. C. (1996) · Proceedings of the National Academy of Sciences

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 262

Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation.

Lang, C., Barco, A., Zablow, L., Kandel, E. R., Siegelbaum, S. A., & Zakharenko, S. S. (2004) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 245

Recruitment of New Sites of Synaptic Transmission During the cAMP-Dependent Late Phase of LTP at CA3–CA1 Synapses in the Hippocampus

Bolshakov, V. Y., Golan, H., Kandel, E. R., & Siegelbaum, S. A. (1997) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 219

Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction

Santoro, B., Wainger, B. J., & Siegelbaum, S. A. (2004) · The Journal of Neuroscience

Ion channel regulation and functionNeuroscience and Neuropharmacology Research

Cited by 210

A role for synaptic inputs at distal dendrites: instructive signals for hippocampal long-term plasticity

Dudman, J. T., Tsay, D., & Siegelbaum, S. A. (2007) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 192

HCN hyperpolarization-activated cation channels inhibit EPSPs by interactions with M-type K(+) channels

George, M. S., Abbott, L. F., & Siegelbaum, S. A. (2009) · Nature Neuroscience

Ion channel regulation and functionNeuroscience and Neuropharmacology Research

Cited by 187

Midbrain dopamine neurons bidirectionally regulate CA3-CA1 synaptic drive

Rosen, Z. B., Cheung, S., & Siegelbaum, S. A. (2015) · Nature Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 183

Age-Dependent Specific Changes in Area CA2 of the Hippocampus and Social Memory Deficit in a Mouse Model of the 22q11.2 Deletion Syndrome

Piskorowski, R. A., Nasrallah, K., Diamantopoulou, A., Mukai, J., Hassan, S. I., Siegelbaum, S. A., Gogos, J. A., & Chevaleyre, V. (2016) · Neuron

Schizophrenia research and treatmentMemory and Neural Mechanisms

Cited by 180

Learning-related synaptic plasticity: LTP and LTD

Siegelbaum, S. A., & Kandel, E. R. (1991) · Current Opinion in Neurobiology

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 168

A Cortico-Hippocampal Learning Rule Shapes Inhibitory Microcircuit Activity to Enhance Hippocampal Information Flow

Basu, J., Srinivas, K. V., Cheung, S. K., Taniguchi, H., Huang, Z. J., & Siegelbaum, S. A. (2013) · Neuron

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 122

Coding of social novelty in the hippocampal CA2 region and its disruption and rescue in a 22q11.2 microdeletion mouse model

Donegan, M. L., Stefanini, F., Meira, T., Gordon, J. A., Fusi, S., & Siegelbaum, S. A. (2020) · Nature Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 114

Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory

Leroy, F., Brann, D. H., Meira, T., & Siegelbaum, S. A. (2017) · Neuron

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 91

Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation

Huang, Y.-Y., Zakharenko, S. S., Schoch, S., Kaeser, P. S., Janz, R., Südhof, T. C., Siegelbaum, S. A., & Kandel, E. R. (2005) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 65