Klunk, William E.

Distinct cytokine profiles in human brains resilient to Alzheimer's pathology

Barroeta-Espar, I., Weinstock, L. D., Perez-Nievas, B. G., Meltzer, A. C., Siao Tick Chong, M., Amaral, A. C., Murray, M. E., Moulder, K. L., Morris, J. C., Cairns, N. J., et al. (2019) · Neurobiology of Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 133

The Long-Term Effects of Conventional and Atypical Antipsychotics in Patients With Probable Alzheimer’s Disease

Lopez, O. L., Becker, J. T., Chang, Y.-F., Sweet, R. A., Aizenstein, H., Snitz, B., Saxton, J., McDade, E., Kamboh, M. I., DeKosky, S. T., et al. (2013) · American Journal of Psychiatry

Dementia and Cognitive Impairment ResearchPharmaceutical Practices and Patient Outcomes

Cited by 129

Utilizing the Centiloid scale in cross-sectional and longitudinal PiB PET studies

Su, Y., Flores, S., Hornbeck, R. C., Speidel, B., Vlassenko, A. G., Gordon, B. A., Koeppe, R. A., Klunk, W. E., Xiong, C., Morris, J. C., et al. (2018) · NeuroImage: Clinical

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 126

Plasma biosignature and brain pathology related to persistent cognitive impairment in late-life depression

Diniz, B. S., Sibille, E., Ding, Y., Tseng, G., Aizenstein, H. J., Lotrich, F., Becker, J. T., Lopez, O. L., Lotze, M. T., Klunk, W. E., et al. (2015) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchTreatment of Major Depression

Cited by 116

Correspondence between in vivo 11C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques

Driscoll, I., Troncoso, J. C., Rudow, G., Sojkova, J., Pletnikova, O., Zhou, Y., Kraut, M. A., Ferrucci, L., Mathis, C. A., Klunk, W. E., et al. (2012) · Acta Neuropathologica

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 104

Reliability of NINDS‐AIREN clinical criteria for the diagnosis of vascular dementia

Lopez, O. L., Larumbe, M. R., Becker, J. T., Rezek, D., Rosen, J., Klunk, W., & DeKosky, S. T. (1994) · Neurology

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 103

In vivo assessment of amyloid‐β deposition in nondemented very elderly subjects

Mathis, C. A., Kuller, L. H., Klunk, W. E., Snitz, B. E., Price, J. C., Weissfeld, L. A., Rosario, B. L., Lopresti, B. J., Saxton, J. A., Aizenstein, H. J., et al. (2013) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 98

Imaging the pathology of Alzheimer's disease: amyloid-imaging with positron emission tomography

Klunk, W. E., Engler, H., Nordberg, A., Bacskai, B. J., Wang, Y., Price, J. C., Bergström, M., Hyman, B. T., Långström, B., & Mathis, C. A. (2003) · Neuroimaging Clinics of North America

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 96

Amyloid-β Imaging in Older Adults Presenting to a Memory Clinic with Subjective Cognitive Decline: A Pilot Study

Snitz, B. E., Lopez, O. L., McDade, E., Becker, J. T., Cohen, A. D., Price, J. C., Mathis, C. A., & Klunk, W. E. (2015) · Journal of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 93

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., et al. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 88

APOE ε4 associates with microglial activation independently of Aβ plaques and tau tangles

Ferrari-Souza, J. P., Lussier, F. Z., Leffa, D. T., Therriault, J., Tissot, C., Bellaver, B., Ferreira, P. C. L., Malpetti, M., Wang, Y.-T., Povala, G., et al. (2023) · Science Advances

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 81

[F‐18]AV‐1451 positron emission tomography retention in choroid plexus: More than “off‐target” binding

Ikonomovic, M. D., Abrahamson, E. E., Price, J. C., Mathis, C. A., & Klunk, W. E. (2016) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 81

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging

(ADNI), F. T. A. D. N. I., Yan, Q., Nho, K., Del-Aguila, J. L., Wang, X., Risacher, S. L., Fan, K.-H., Snitz, B. E., Aizenstein, H. J., Mathis, C. A., et al. (2021) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 73

The road ahead to cure Alzheimer’s disease: development of biological markers and neuroimaging methods for prevention trials across all stages and target populations

Cavedo, E., Lista, S., Khachaturian, Z., Aisen, P., Amouyel, P., Herholz, K., Jack Jr, C. R., Sperling, R., Cummings, J., Blennow, K., et al. (2014) · The Journal of Prevention of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 67

Detection of Brain Tau Pathology in Down Syndrome Using Plasma Biomarkers

Janelidze, S., Christian, B. T., Price, J., Laymon, C., Schupf, N., Klunk, W. E., Lott, I., Silverman, W., Rosas, H. D., Zaman, S., et al. (2022) · JAMA Neurology

Dementia and Cognitive Impairment ResearchDown syndrome and intellectual disability research

Cited by 60

Characterizing the emergence of amyloid and tau burden in Down syndrome

Zammit, M. D., Betthauser, T. J., McVea, A. K., Laymon, C. M., Tudorascu, D. L., Johnson, S. C., Hartley, S. L., Converse, A. K., Minhas, D. S., Zaman, S. H., et al. (2024) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 60

Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer’s Disease: Results from the DIAN Study Group

Su, Y., Blazey, T. M., Owen, C. J., Christensen, J. J., Friedrichsen, K., Joseph-Mathurin, N., Wang, Q., Hornbeck, R. C., Ances, B. M., Snyder, A. Z., et al. (2016) · PLOS ONE

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 56

APOEε4 potentiates amyloid β effects on longitudinal tau pathology

Ferrari-Souza, J. P., Bellaver, B., Ferreira, P. C. L., Benedet, A. L., Povala, G., Lussier, F. Z., Leffa, D. T., Therriault, J., Tissot, C., Soares, C., et al. (2023) · Nature Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 43

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

Wisch, J. K., McKay, N. S., Boerwinkle, A. H., Kennedy, J., Flores, S., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Rafii, M. S., et al. (2024) · The Lancet Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 37

Dendritic Spine Density, Morphology, and Fibrillar Actin Content Surrounding Amyloid-β Plaques in a Mouse Model of Amyloid-β Deposition

Kirkwood, C. M., Ciuchta, J., Ikonomovic, M. D., Fish, K. N., Abrahamson, E. E., Murray, P. S., Klunk, W. E., & Sweet, R. A. (2013) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 35

The effect of amyloid deposition on longitudinal resting-state functional connectivity in cognitively normal older adults

Lin, C., Ly, M., Karim, H. T., Wei, W., Snitz, B. E., Klunk, W. E., & Aizenstein, H. J. (2020) · Alzheimer's Research & Therapy

Functional Brain Connectivity StudiesDementia and Cognitive Impairment Research

Cited by 19