Tonegawa, Susumu

Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

Miyakawa, T., Leiter, L. M., Gerber, D. J., Gainetdinov, R. R., Sotnikova, T. D., Zeng, H., Caron, M. G., & Tonegawa, S. (2003) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentSignaling Pathways in Disease

Cited by 489

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

Silva, A. J., Simpson, E. M., Takahashi, J. S., Lipp, H.-P., Nakanishi, S., Wehner, J. M., Giese, K. P., Tully, T., Abel, T., Chapman, P. F., et al. (1997) · Neuron

Animal Genetics and ReproductionMemory and Neural Mechanisms

Cited by 479

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

Heilig, J. S., & Tonegawa, S. (1986) · Nature

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 448

A clustered plasticity model of long-term memory engrams.

Govindarajan, A., Kelleher, R. J., & Tonegawa, S. (2006) · Nature reviews. Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 355

The Dendritic Branch Is the Preferred Integrative Unit for Protein Synthesis-Dependent LTP

Govindarajan, A., Israely, I., Huang, S.-Y., & Tonegawa, S. (2011) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 349

Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain

Chen, C., & Tonegawa, S. (1997) · Annual Review of Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 300

Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context

Wagatsuma, A., Okuyama, T., Sun, C., Smith, L. M., Abe, K., & Tonegawa, S. (2018) · Proceedings of the National Academy of Sciences

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 283

Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice

Hayashi, M. L., Rao, B. S. S., Seo, J.-S., Choi, H.-S., Dolan, B. M., Choi, S.-Y., Chattarji, S., & Tonegawa, S. (2007) · Proceedings of the National Academy of Sciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 281

Altered Cortical Synaptic Morphology and Impaired Memory Consolidation in Forebrain- Specific Dominant-Negative PAK Transgenic Mice

Hayashi, M. L., Choi, S.-Y., Rao, B. S. S., Jung, H.-Y., Lee, H.-K., Zhang, D., Chattarji, S., Kirkwood, A., & Tonegawa, S. (2004) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 280

t Brain-Derived Neurotrophic Factor Overexpression Induces Precocious Critical Period in Mouse Visual Cortex

Hanover, T. J. L., Huang, Z. J., Tonegawa, S., & Stryker, M. P. (1999) · The Journal of Neuroscience

Visual perception and processing mechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 265

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

Dolan, B. M., Duron, S. G., Campbell, D. A., Vollrath, B., Rao, B. S. S., Ko, H.-Y., Lin, G. G., Govindarajan, A., Choi, S.-Y., & Tonegawa, S. (2013) · Proceedings of the National Academy of Sciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 260

Diversity of γδ T-cell receptors on murine intestinal intraepithelial lymphocytes

Takagaki, Y., DeCloux, A., Bonneville, M., & Tonegawa, S. (1989) · Nature

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 217

Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF

Gianfranceschi, L., Siciliano, R., Walls, J., Morales, B., Kirkwood, A., Huang, Z. J., Tonegawa, S., & Maffei, L. (2003) · Proceedings of the National Academy of Sciences

Visual perception and processing mechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 201

Lack of Self-Administration of Cocaine in Dopamine D 1 Receptor Knock-Out Mice

Caine, S. B., Thomsen, M., Gabriel, K. I., Berkowitz, J. S., Gold, L. H., Koob, G. F., Tonegawa, S., Zhang, J., & Xu, M. (2007) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 183

Hippocampal lesions impair contextual fear conditioning in two strains of mice.

Chen, C., Kim, J. J., Thompson, R. F., & Tonegawa, S. (1996) · Behavioral Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 148

Hippocampal neurons represent events as transferable units of experience

Sun, C., Yang, W., Martin, J., & Tonegawa, S. (2020) · Nature Neuroscience

Memory and Neural MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 135

Entorhinal–hippocampal neuronal circuits bridge temporally discontiguous events

Kitamura, T., Macdonald, C. J., & Tonegawa, S. (2015) · Learning & Memory

Memory and Neural MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 105

CA1 Long-Term Potentiation Is Diminished but Present in Hippocampal Slices from α-CaMKII Mutant Mice

Hinds, H. L., Tonegawa, S., & Malinow, R. (1998) · Learning & Memory

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 86

Control of CA3 Output by Feedforward Inhibition Despite Developmental Changes in the Excitation–Inhibition Balance

Torborg, C. L., Nakashiba, T., Tonegawa, S., & McBain, C. J. (2010) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 76

The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons

Berezovska, O., Frosch, M., McLean, P., Knowles, R., Koo, E., Kang, D., Shen, J., Lu, F. M., Lux, S. E., Tonegawa, S., et al. (1999) · Molecular Brain Research

Alzheimer's disease research and treatmentsDevelopmental Biology and Gene Regulation

Cited by 68

NMDA signaling in CA1 mediates selectively the spatial component of episodic memory

Place, R., Lykken, C., Beer, Z., Suh, J., McHugh, T. J., Tonegawa, S., Eichenbaum, H., & Sauvage, M. M. (2012) · Learning & Memory

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 46