Correia, Bruno E.

Proteome-wide covalent ligand discovery in native biological systems

Backus, K. M., Correia, B. E., Lum, K. M., Forli, S., Horning, B. D., González-Páez, G. E., Chatterjee, S., Lanning, B. R., Teijaro, J. R., Olson, A. J., et al. (2016) · Nature

Click Chemistry and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 940

Macromolecular modeling and design in Rosetta: recent methods and frameworks

Leman, J. K., Weitzner, B. D., Lewis, S. M., Adolf-Bryfogle, J., Alam, N., Alford, R. F., Aprahamian, M., Baker, D., Barlow, K. A., Barth, P., et al. (2020) · Nature Methods

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 888

Proof of principle for epitope-focused vaccine design

Correia, B. E., Bates, J. T., Loomis, R. J., Baneyx, G., Carrico, C., Jardine, J. G., Rupert, P., Correnti, C., Kalyuzhniy, O., Vittal, V., et al. (2014) · Nature

vaccines and immunoinformatics approachesSARS-CoV-2 and COVID-19 Research

Cited by 555

Scaffolding protein functional sites using deep learning

Wang, J., Lisanza, S., Juergens, D., Tischer, D., Watson, J. L., Castro, K. M., Ragotte, R., Saragovi, A., Milles, L. F., Baek, M., et al. (2022) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 487

Global profiling of lysine reactivity and ligandability in the human proteome

Hacker, S. M., Backus, K. M., Lazear, M. R., Forli, S., Correia, B. E., & Cravatt, B. F. (2017) · Nature Chemistry

Click Chemistry and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 485

Ligand and Target Discovery by Fragment-Based Screening in Human Cells

Parker, C. G., Galmozzi, A., Wang, Y., Correia, B. E., Sasaki, K., Joslyn, C. M., Kim, A. S., Cavallaro, C. L., Lawrence, R. M., Johnson, S. R., et al. (2017) · Cell

Click Chemistry and ApplicationsComputational Drug Discovery Methods

Cited by 439

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning

Mason, D. M., Friedensohn, S., Weber, C. R., Jordi, C., Wagner, B., Meng, S. M., Ehling, R. A., Bonati, L., Dahinden, J., Gainza, P., et al. (2021) · Nature Biomedical Engineering

Monoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approaches

Cited by 308

Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold

Azoitei, M. L., Correia, B. E., Ban, Y.-E. A., Carrico, C., Kalyuzhniy, O., Chen, L., Schroeter, A., Huang, P.-S., McLellan, J. S., Kwong, P. D., et al. (2011) · Science

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 224

De novo protein design enables the precise induction of RSV-neutralizing antibodies

Sesterhenn, F., Yang, C., Bonet, J., Cramer, J. T., Wen, X., Wang, Y., Chiang, C.-I., Abriata, L. A., Kucharska, I., Castoro, G., et al. (2020) · Science

vaccines and immunoinformatics approachesProtein Structure and Dynamics

Cited by 191

An atlas of protein homo-oligomerization across domains of life

Schweke, H., Levin, T., Pacesa, M., Goverde, C. A., Kumar, P., Duhoo, Y., Dornfeld, L. J., Dubreuil, B., Georgeon, S., Ovchinnikov, S., et al. (2023) · Cell

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 144

An atlas of protein homo-oligomerization across domains of life

Schweke, H., Pacesa, M., Levin, T., Goverde, C. A., Kumar, P., Duhoo, Y., Dornfeld, L. J., Dubreuil, B., Georgeon, S., Ovchinnikov, S., et al. (2024) · Cell

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 144

A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells

Procko, E., Berguig, G. Y., Shen, B. W., Song, Y., Frayo, S., Convertine, A. J., Margineantu, D., Booth, G., Correia, B. E., Cheng, Y., et al. (2014) · Cell

Cell death mechanisms and regulationChemical Synthesis and Analysis

Cited by 127

De novo protein design by inversion of the AlphaFold structure prediction network

Goverde, C., Wolf, B., Khakzad, H., Rosset, S., & Correia, B. E. (2022) · Protein Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 103

De novo protein design by inversion of the AlphaFold structure prediction network

Goverde, C. A., Wolf, B., Khakzad, H., Rosset, S., & Correia, B. E. (2023) · Protein Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 103

Chemoproteomic profiling and discovery of protein electrophiles in human cells

Matthews, M. L., He, L., Horning, B. D., Olson, E. J., Correia, B. E., Yates, J. R., Dawson, P. E., & Cravatt, B. F. (2017) · Nature Chemistry

Click Chemistry and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 90

Bottom-up de novo design of functional proteins with complex structural features

Yang, C., Sesterhenn, F., Bonet, J., van Aalen, E. A., Scheller, L., Abriata, L. A., Cramer, J. T., Wen, X., Rosset, S., Georgeon, S., et al. (2021) · Nature Chemical Biology

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 84

Assessing and enhancing foldability in designed proteins

Listov, D., Lipsh‐Sokolik, R., Rosset, S., Yang, C., Correia, B. E., & Fleishman, S. J. (2022) · Protein Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 24

A generic framework for hierarchical de novo protein design

Harteveld, Z., Bonet, J., Rosset, S., Yang, C., Sesterhenn, F., & Correia, B. E. (2022) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 21

A generic framework for hierarchical de novo protein design

Harteveld, Z., Bonet, J., Rosset, S., Yang, C., Sesterhenn, F., & Correia, B. E. (2022) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 21

Exploring “dark-matter” protein folds using deep learning

Harteveld, Z., Van Hall-Beauvais, A., Morozova, I., Southern, J., Goverde, C., Georgeon, S., Rosset, S., Defferrard, M., Loukas, A., Vandergheynst, P., et al. (2024) · Cell Systems

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 13

Accurate single-domain scaffolding of three nonoverlapping protein epitopes using deep learning

Castro, K. M., Watson, J. L., Wang, J., Southern, J., Ayardulabi, R., Georgeon, S., Rosset, S., Baker, D., & Correia, B. E. (2026) · Nature Chemical Biology

Protein Structure and Dynamicsvaccines and immunoinformatics approaches

Cited by 13

Exploring “dark matter” protein folds using deep learning

Harteveld, Z., Van Hall-Beauvais, A., Morozova, I., Southern, J., Goverde, C., Georgeon, S., Rosset, S., Defferrard, M., Loukas, A., Vandergheynst, P., et al. (2023) · Cell Systems

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 13

Mapping targetable sites on the human surfaceome for the design of novel binders

Balbi, P. E. M., Sadek, A., Marchand, A., Yu, T.-Y., Damjanovic, J., Georgeon, S., Schmidt, J., Fulle, S., Yang, C., Khakzad, H., et al. (2024) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 6

Mapping targetable sites on the human surfaceome for the design of novel binders

Balbi, P. E. M., Sadek, A., Marchand, A., Yu, T.-Y., Damjanovic, J., Georgeon, S., Schmidt, J., Fulle, S., Yang, C., Khakzad, H., et al. (2026) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsChemical Synthesis and Analysis

Cited by 6