Pellerin, Luc

Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization.

Pellerin, L., & Magistretti, P. J. (1994) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 2,927

Reactive astrocyte nomenclature, definitions, and future directions

Escartin, C., Galea, E., Lakatos, A., O’Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., et al. (2021) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 2,513

Oligodendroglia metabolically support axons and contribute to neurodegeneration

Lee, Y., Morrison, B. M., Li, Y., Lengacher, S., Farah, M. H., Hoffman, P. N., Liu, Y., Tsingalia, A., Jin, L., Zhang, P.-W., et al. (2012) · Nature

Multiple Sclerosis Research StudiesAmyotrophic Lateral Sclerosis Research

Cited by 1,664

Energy on demand.

Magistretti, P. J., Pellerin, L., Rothman, D. L., & Shulman, R. G. (1999) · Science

Neuroscience and Neuropharmacology ResearchAdvanced MRI Techniques and Applications

Cited by 1,170

Activity-dependent regulation of energy metabolism by astrocytes: an update

Pellerin, L., Bouzier‐Sore, A., Aubert, A., Serres, S., Merle, M., Costalat, R., & Magistretti, P. J. (2007) · Glia

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 805

Monocarboxylate transporters in the central nervous system: distribution, regulation and function

Pierre, K., & Pellerin, L. (2005) · Journal of Neurochemistry

Drug Transport and Resistance MechanismsBarrier Structure and Function Studies

Cited by 744

The selfish brain: Competition for energy resources

Peters, A., Schweiger, U., Pellerin, L., Hubold, C., Oltmanns, K. M., Conrad, M., Schultes, B., Born, J., & Fehm, H. L. (2004) · Neuroscience & Biobehavioral Reviews

Regulation of Appetite and ObesityStress Responses and Cortisol

Cited by 489

Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain

Bittar, P. G., Charnay, Y., Pellerin, L., Bouras, C., & Magistretti, P. J. (1996) · Journal of Cerebral Blood Flow & Metabolism

Neuroscience and Neuropharmacology ResearchAdvanced MRI Techniques and Applications

Cited by 423

Astrocyte Biomarkers in Alzheimer’s Disease

Carter, S. F., Herholz, K., Rosa-Neto, P., Pellerin, L., Nordberg, A., & Zimmer, E. R. (2019) · Trends in Molecular Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 355

[18F]FDG PET signal is driven by astroglial glutamate transport

Zimmer, E. R., Parent, M. J., Souza, D. G., Leuzy, A., Lecrux, C., Kim, H.-I., Gauthier, S., Pellerin, L., Hamel, E., & Rosa-Neto, P. (2017) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchMedical Imaging Techniques and Applications

Cited by 343

Lactate is a Preferential Oxidative Energy Substrate over Glucose for Neurons in Culture

Bouzier-Sore, A.-K., Voisin, P., Canioni, P., Magistretti, P. J., & Pellerin, L. (2003) · Journal of Cerebral Blood Flow & Metabolism

Neuroscience and Neuropharmacology ResearchCancer, Hypoxia, and Metabolism

Cited by 328

Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study

Bouzier‐Sore, A., Voisin, P., Bouchaud, V., Bezancon, E., Franconi, J., & Pellerin, L. (2006) · European Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchCancer, Hypoxia, and Metabolism

Cited by 265

Transfer of glycogen-derived lactate from astrocytes to axons via specific monocarboxylate transporters supports mouse optic nerve activity

Tekkök, S. B., Brown, A. M., Westenbroek, R., Pellerin, L., & Ransom, B. R. (2005) · Journal of Neuroscience Research

Neuroscience and Neuropharmacology ResearchNeuroprotection in Cerebral Ischemia

Cited by 224

Neurotransmitters regulate energy metabolism in astrocytes: implications for the metabolic trafficking between neural cells

Magistretti, P. J., Sorg, O., Yu, N., Martin, J.-L., & Pellerin, L. (1994) · Developmental Neuroscience

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 205

Unraveling the complex metabolic nature of astrocytes

Bouzier-Sore, A.-K., & Pellerin, L. (2013) · Frontiers in Cellular Neuroscience

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 134

Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-analysis

Bellaver, B., Ferrari-Souza, J. P., Uglione da Ros, L., Carter, S. F., Rodriguez-Vieitez, E., Nordberg, A., Pellerin, L., Rosa-Neto, P., Leffa, D. T., & Zimmer, E. R. (2021) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 123

Differential messenger RNA distribution of lactate dehydrogenase LDH-1 and LDH-5 isoforms in the rat brain

Laughton, J. D., Charnay, Y., Belloir, B., Pellerin, L., Magistretti, P. J., & Bouras, C. (2000) · Neuroscience

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 77

A neuronal MCT2 knockdown in the rat somatosensory cortex reduces both the NMR lactate signal and the BOLD response during whisker stimulation

Mazuel, L., Blanc, J., Repond, C., Bouchaud, V., Raffard, G., Déglon, N., Bonvento, G., Pellerin, L., & Bouzier-Sore, A.-K. (2017) · PLoS ONE

Advanced MRI Techniques and ApplicationsNeuroscience and Neuropharmacology Research

Cited by 44

Clozapine induces astrocyte-dependent FDG-PET hypometabolism

Rocha, A., Bellaver, B., Souza, D. G., Schu, G., Fontana, I. C., Venturin, G. T., Greggio, S., Fontella, F. U., Schiavenin, M. L., Machado, L. S., et al. (2022) · European Journal of Nuclear Medicine and Molecular Imaging

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 31

Comment on “Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases”

Zimmer, E. R., Pascoal, T. A., Rosa-Neto, P., Nordberg, A., & Pellerin, L. (2022) · Science Translational Medicine

Neuroinflammation and Neurodegeneration MechanismsMedical Imaging Techniques and Applications

Cited by 17