Wherry, E. John
University of Pennsylvania
58 papers on CoChatORCID 0000-0003-0477-1956
Most cited papers
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Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination
Goel, R. R., Apostolidis, S. A., Painter, M. M., Mathew, D., Pattekar, A., Kuthuru, O., Gouma, S., Hicks, P., Meng, W., Rosenfeld, A. M., et al. (2021) · Science Immunology
SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations
Cited by 655
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Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection
Teijaro, J. R., Turner, D., Pham, Q., Wherry, E. J., Lefrançois, L., & Farber, D. L. (2011) · The Journal of Immunology
T-cell and B-cell ImmunologyInfluenza Virus Research Studies
Cited by 641
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Dynamic T cell migration program provides resident memory within intestinal epithelium
Masopust, D., Choo, D., Vezys, V., Wherry, E. J., Duraiswamy, J., Akondy, R., Wang, J., Casey, K. A., Barber, D. L., Kawamura, K. S., et al. (2010) · Journal of Experimental Medicine
T-cell and B-cell ImmunologyCell Adhesion Molecules Research
Cited by 628
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Heterologous immunity provides a potent barrier to transplantation tolerance
Adams, A. B., Williams, M. A., Jones, T. R., Shirasugi, N., Durham, M. M., Kaech, S. M., Wherry, E. J., Onami, T., Lanier, J. G., Kokko, K. E., et al. (2003) · Journal of Clinical Investigation
T-cell and B-cell ImmunologyTransplantation: Methods and Outcomes
Cited by 616
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Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection
Yao, C., Sun, H.-W., Lacey, N. E., Ji, Y., Moseman, E. A., Shih, H.-Y., Heuston, E. F., Kirby, M., Anderson, S., Cheng, J., et al. (2019) · Nature Immunology
T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers
Cited by 549
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Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
Benci, J. L., Johnson, L. R., Choa, R., Xu, Y., Qiu, J., Zhou, Z., Xu, B., Ye, D., Nathanson, K. L., June, C. H., et al. (2019) · Cell
Cancer Immunotherapy and Biomarkersinterferon and immune responses
Cited by 541
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CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer
Bange, E. M., Han, N. A., Wileyto, P., Kim, J. Y., Gouma, S., Robinson, J., Greenplate, A. R., Hwee, M. A., Porterfield, F., Owoyemi, O., et al. (2021) · Nature Medicine
COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research
Cited by 519
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Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination
Painter, M. M., Mathew, D., Goel, R. R., Apostolidis, S. A., Pattekar, A., Kuthuru, O., Baxter, A. E., Herati, R. S., Oldridge, D. A., Gouma, S., et al. (2021) · Immunity
SARS-CoV-2 and COVID-19 ResearchT-cell and B-cell Immunology
Cited by 499
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Induction of T-cell immunity overcomes complete resistance to PD-1 and CTLA-4 blockade and improves survival in pancreatic carcinoma
Winograd, R., Byrne, K. T., Evans, R. A., Odorizzi, P. M., Meyer, A. R. L., Bajor, D. L., Clendenin, C., Stanger, B. Z., Furth, E. E., Wherry, E. J., et al. (2015) · Cancer Immunology Research
Cancer Immunotherapy and BiomarkersPancreatic and Hepatic Oncology Research
Cited by 459
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Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial
Padrón, L. J., Maurer, D. M., O’Hara, M. H., O’Reilly, E. M., Wolff, R. A., Wainberg, Z. A., Ko, A. H., Fisher, G., Rahma, O., Lyman, J. P., et al. (2022) · Nature Medicine
Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers
Cited by 384
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Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade
Nakamoto, N., Cho, H., Shaked, A., Olthoff, K., Valiga, M. E., Kaminski, M., Gostick, E., Price, D. A., Freeman, G. J., Wherry, E. J., et al. (2009) · PLoS Pathogens
Hepatitis C virus researchCancer Immunotherapy and Biomarkers
Cited by 380
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The enteric nervous system relays psychological stress to intestinal inflammation
Schneider, K. M., Blank, N., Alvarez, Y., Thum, K., Lundgren, P., Litichevskiy, L., Sleeman, M., Bahnsen, K., Kim, J., Kardo, S., et al. (2023) · Cell
Inflammatory Bowel DiseaseGastrointestinal motility and disorders
Cited by 344
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The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs
Virtue, A. T., McCright, S. J., Wright, J. M., Jimenez, M. T., Mowel, W. K., Kotzin, J. J., Joannas, L., Basavappa, M. G., Spencer, S. P., Clark, M. L., et al. (2019) · Science Translational Medicine
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 317
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CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study
O'Hara, M. H., O'Reilly, E. M., Varadhachary, G., Wolff, R. A., Wainberg, Z. A., Ko, A. H., Fisher, G., Rahma, O., Lyman, J. P., Cabanski, C. R., et al. (2021) · The Lancet Oncology
Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers
Cited by 307
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Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics
Giles, J. R., Ngiow, S. F., Manne, S., Baxter, A. E., Khan, O., Wang, P., Staupe, R., Abdel-Hakeem, M. S., Huang, H., Mathew, D., et al. (2022) · Nature Immunology
T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers
Cited by 264
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Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells
Johnson, J. L., Georgakilas, G., Petrovic, J., Kurachi, M., Cai, S., Harly, C., Pear, W. S., Bhandoola, A., Wherry, E. J., & Vahedi, G. (2018) · Immunity
Genomics and Chromatin DynamicsT-cell and B-cell Immunology
Cited by 226
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Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine
Goel, R. R., Painter, M. M., Lundgreen, K. A., Apostolidis, S. A., Baxter, A. E., Giles, J. R., Mathew, D., Pattekar, A., Reynaldi, A., Khoury, D. S., et al. (2022) · Cell
SARS-CoV-2 and COVID-19 ResearchImmune responses and vaccinations
Cited by 207
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Neoadjuvant Selicrelumab, an agonist CD40 antibody, induces changes in the tumor microenvironment in patients with resectable pancreatic cancer
Byrne, K. T., Betts, C. B., Mick, R., Sivagnanam, S., Bajor, D. L., Laheru, D. A., Chiorean, E. G., O'Hara, M. H., Liudahl, S. M., Newcomb, C., et al. (2021) · Clinical Cancer Research
Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers
Cited by 199
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Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals
Lederer, K., Parvathaneni, K., Painter, M. M., Bettini, E., Agarwal, D., Lundgreen, K. A., Weirick, M., Goel, R. R., Xu, X., Drapeau, E. M., et al. (2021) · Cell
SARS-CoV-2 and COVID-19 ResearchT-cell and B-cell Immunology
Cited by 179
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Circulating CXCR5+PD-1+ Response Predicts Influenza Vaccine Antibody Responses in Young Adults but not Elderly Adults
Herati, R. S., Reuter, M. A., Dolfi, D. V., Mansfield, K. D., Aung, H., Badwan, O. Z., Kurupati, R. K., Kannan, S., Ertl, H., Schmader, K. E., et al. (2014) · The Journal of Immunology
Influenza Virus Research StudiesT-cell and B-cell Immunology
Cited by 177
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Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells
Herati, R. S., Muselman, A., Vella, L., Bengsch, B., Parkhouse, K., Del Alcazar, D., Kotzin, J., Doyle, S. A., Tebas, P., Hensley, S. E., et al. (2017) · Science Immunology
T-cell and B-cell ImmunologyInfluenza Virus Research Studies
Cited by 167
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T follicular helper cells in human efferent lymph retain lymphoid characteristics
Vella, L. A., Buggert, M., Manne, S., Herati, R. S., Sayin, I., Kuri-Cervantes, L., Bukh Brody, I., O’Boyle, K. C., Kaprielian, H., Giles, J. R., et al. (2019) · Journal of Clinical Investigation
T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis
Cited by 155
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Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity
Zappasodi, R., Budhu, S., Hellmann, M. D., Postow, M. A., Senbabaoglu, Y., Manne, S., Gasmi, B., Liu, C., Zhong, H., Li, Y., et al. (2018) · Cancer Cell
Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology
Cited by 142
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SARS-CoV-2 seroprevalence among parturient women in Philadelphia
Flannery, D. D., Gouma, S., Dhudasia, M. B., Mukhopadhyay, S., Pfeifer, M. R., Woodford, E. C., Gerber, J. S., Arevalo, C. P., Bolton, M. J., Weirick, M. E., et al. (2020) · Science Immunology
SARS-CoV-2 and COVID-19 ResearchCOVID-19 Impact on Reproduction
Cited by 125
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