Weissleder, Ralph

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles

Ricklefs, F. L., Alayo, Q., Krenzlin, H., Mahmoud, A. B., Speranza, M. C., Nakashima, H., Hayes, J. L., Lee, K., Balaj, L., Passaro, C., et al. (2018) · Science Advances

Extracellular vesicles in diseaseCancer Immunotherapy and Biomarkers

Cited by 610

Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction

Heidt, T., Courties, G., Dutta, P., Sager, H. B., Sebas, M., Iwamoto, Y., Sun, Y., Da Silva, N., Panizzi, P., van der Laan, A. M., et al. (2014) · Circulation Research

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

Cited by 607

Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis

Nahrendorf, M., Jaffer, F. A., Kelly, K. A., Sosnovik, D. E., Aikawa, E., Libby, P., & Weissleder, R. (2006) · Circulation

Atherosclerosis and Cardiovascular DiseasesCerebrovascular and Carotid Artery Diseases

Cited by 602

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

Lai, C. P., Kim, E. Y., Badr, C. E., Weissleder, R., Mempel, T. R., Tannous, B. A., & Breakefield, X. O. (2015) · Nature Communications

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 574

Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

Nahrendorf, M., Zhang, H., Hembrador, S., Panizzi, P., Sosnovik, D. E., Aikawa, E., Libby, P., Swirski, F. K., & Weissleder, R. (2008) · Circulation

Cardiac Imaging and DiagnosticsRadiopharmaceutical Chemistry and Applications

Cited by 559

Intravital imaging

Pittet, M. J., & Weissleder, R. (2011) · Cell

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

Cited by 466

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

Ji, H., Li, D., Chen, L., Shimamura, T., Kobayashi, S., McNamara, K., Mahmood, U., Mitchell, A., Sun, Y., Al-Hashem, R., et al. (2006) · Cancer Cell

Lung Cancer Treatments and MutationsHER2/EGFR in Cancer Research

Cited by 462

Tumour‐associated macrophages act as a slow‐release reservoir of nano‐therapeutic Pt(IV) pro‐drug

Miller, M. A., Zheng, Y.-R., Gadde, S., Pfirschke, C., Zope, H., Engblom, C., Kohler, R. H., Iwamoto, Y., Yang, K. S., Askevold, B., et al. (2015) · Nature Communications

Nanoparticle-Based Drug DeliveryImmune cells in cancer

Cited by 441

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Theurl, I., Hilgendorf, I., Nairz, M., Tymoszuk, P., Haschka, D., Asshoff, M., He, S., Gerhardt, L. M. S., Holderried, T. A. W., Seifert, M., et al. (2016) · Nature Medicine

Phagocytosis and Immune RegulationIron Metabolism and Disorders

Cited by 412

MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell–Delivered S-TRAIL in Human Gliomas

Corsten, M. F., Miranda, R., Kasmieh, R., Krichevsky, A. M., Weissleder, R., & Shah, K. (2007) · Cancer Research

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 406

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease

Swirski, F. K., Pittet, M. J., Kircher, M. F., Aikawa, E., Jaffer, F. A., Libby, P., & Weissleder, R. (2006) · Proceedings of the National Academy of Sciences

Atherosclerosis and Cardiovascular DiseasesCholesterol and Lipid Metabolism

Cited by 367

DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents

Perez, J. M., O'Loughin, T., Simeone, F. J., Weissleder, R., & Josephson, L. (2002) · Journal of the American Chemical Society

Characterization and Applications of Magnetic NanoparticlesAdvanced biosensing and bioanalysis techniques

Cited by 355

Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease

McAlpine, C. S., Park, J., Griciuc, A., Kim, E., Choi, S. H., Iwamoto, Y., Kiss, M. G., Christie, K. A., Vinegoni, C., Poller, W. C., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 322

Use of magnetic nanoparticles as nanosensors to probe for molecular interactions

Perez, J. M., Josephson, L., & Weissleder, R. (2004) · ChemBioChem

Characterization and Applications of Magnetic NanoparticlesNMR spectroscopy and applications

Cited by 268

Perturbational profiling of nanomaterial biologic activity

Shaw, S. Y., Westly, E. C., Pittet, M. J., Subramanian, A., Schreiber, S. L., & Weissleder, R. (2008) · Proceedings of the National Academy of Sciences

Nanoparticles: synthesis and applicationsImmunotoxicology and immune responses

Cited by 248

Brain motor and fear circuits regulate leukocytes during acute stress

Poller, W. C., Downey, J., Mooslechner, A. A., Khan, N., Li, L., Chan, C. T., McAlpine, C. S., Xu, C., Kahles, F., He, S., et al. (2022) · Nature

Stress Responses and CortisolCancer, Stress, Anesthesia, and Immune Response

Cited by 234

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients

Gaglia, J. L., Guimaraes, A. R., Harisinghani, M., Turvey, S. E., Jackson, R., Benoist, C., Mathis, D., & Weissleder, R. (2011) · Journal of Clinical Investigation

Diabetes and associated disordersPancreatic function and diabetes

Cited by 209

PepBank - a database of peptides based on sequence text mining and public peptide data sources.

Shtatland, T., Guettler, D., Kossodo, M., Pivovarov, M., & Weissleder, R. (2007) · BMC Bioinformatics

Biomedical Text Mining and OntologiesGenomics and Phylogenetic Studies

Cited by 181

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

Dutta, P., Hoyer, F. F., Grigoryeva, L. S., Sager, H. B., Leuschner, F., Courties, G., Borodovsky, A., Novobrantseva, T., Ruda, V. M., Fitzgerald, K., et al. (2015) · Journal of Experimental Medicine

Hematopoietic Stem Cell TransplantationAtherosclerosis and Cardiovascular Diseases

Cited by 180

High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis

Morishige, K., Kacher, D. F., Libby, P., Josephson, L., Ganz, P., Weissleder, R., & Aikawa, M. (2010) · Circulation

Atherosclerosis and Cardiovascular DiseasesCardiac Imaging and Diagnostics

Cited by 168

A Light‐Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis

McCarthy, J. R., Korngold, E., Weissleder, R., & Jaffer, F. A. (2010) · Small

Nanoplatforms for cancer theranosticsPhotodynamic Therapy Research Studies

Cited by 151

Monocytes re-enter the bone marrow during fasting and alter the host response to infection

Janssen, H., Kahles, F., Liu, D., Downey, J., Koekkoek, L. L., Roudko, V., D’Souza, D., McAlpine, C. S., Halle, L., Poller, W. C., et al. (2023) · Immunity

Dietary Effects on HealthImmune responses and vaccinations

Cited by 142

Accurate measurement of pancreatic islet β-cell mass using a second-generation fluorescent exendin-4 analog

Reiner, T., Thurber, G., Gaglia, J., Vinegoni, C., Liew, C. W., Upadhyay, R., Kohler, R. H., Li, L., Kulkarni, R. N., Benoist, C., et al. (2011) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 120

Liver MR imaging with iron oxides: toward consensus and clinical practice

Weissleder, R. (1994) · Radiology

Advanced MRI Techniques and ApplicationsLiver Disease Diagnosis and Treatment

Cited by 101