Bonifer, Constanze

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma

Lamprecht, B., Walter, K., Kreher, S., Kumar, R., Hummel, M., Lenze, D., Köchert, K., Bouhlel, M. A., Richter, J., Soler, E., et al. (2010) · Nature Medicine

Genomics and Chromatin DynamicsLymphoma Diagnosis and Treatment

Cited by 376

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

Ptasinska, A., Assi, S. A., Mannari, D., James, S. R., Williamson, D., Dunne, J., Hoogenkamp, M., Wu, M., Care, M., McNeill, H., et al. (2012) · Leukemia

Acute Myeloid Leukemia ResearchChromatin Remodeling and Cancer

Cited by 184

Subtype-specific regulatory network rewiring in acute myeloid leukemia

Assi, S. A., Imperato, M. R., Coleman, D. J. L., Pickin, A., Potluri, S., Ptasinska, A., Chin, P. S., Blair, H., Cauchy, P., James, S. R., et al. (2019) · Nature Genetics

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 179

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Leddin, M., Perrod, C., Hoogenkamp, M., Ghani, S., Assi, S., Heinz, S., Wilson, N. K., Follows, G., Schönheit, J., Vockentanz, L., et al. (2011) · Blood

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 131

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

Ghani, S., Riemke, P., Schönheit, J., Lenze, D., Stumm, J., Hoogenkamp, M., Lagendijk, A., Heinz, S., Bonifer, C., Bakkers, J., et al. (2011) · Blood

Hematopoietic Stem Cell TransplantationMicroRNA in disease regulation

Cited by 123

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

Hoogenkamp, M., Lichtinger, M., Krysinska, H., Lancrin, C., Clarke, D., Williamson, A., Mazzarella, L., Ingram, R., Jorgensen, H., Fisher, A., et al. (2009) · Blood

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 121

Inducible chromatin priming is associated with the establishment of immunological memory in T cells

Bevington, S. L., Cauchy, P., Piper, J., Bertrand, E., Lalli, N., Jarvis, R. C., Gilding, L. N., Ott, S., Bonifer, C., & Cockerill, P. N. (2016) · The EMBO Journal

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 110

A Two-Step, PU.1-Dependent Mechanism for Developmentally Regulated Chromatin Remodeling and Transcription of the c-fms Gene

Krysinska, H., Hoogenkamp, M., Ingram, R., Wilson, N., Tagoh, H., Laslo, P., Singh, H., & Bonifer, C. (2007) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 102

The RUNX1–PU.1 axis in the control of hematopoiesis

Imperato, M. R., Cauchy, P., Obier, N., & Bonifer, C. (2015) · International Journal of Hematology

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 94

The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction.

Tagoh, H., Ingram, R., Wilson, N., Salvagiotto, G., Warren, A. J., Clarke, D., Busslinger, M., & Bonifer, C. (2006) · The EMBO Journal

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 74

How transcription factors program chromatin—Lessons from studies of the regulation of myeloid-specific genes

Bonifer, C., Hoogenkamp, M., Krysinska, H., & Tagoh, H. (2008) · Seminars in Immunology

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 27