Koob, George F.

Neuropeptide Y in the central nucleus of the amygdala suppresses dependence-induced increases in alcohol drinking

Gilpin, N. W., Misra, K., & Koob, G. F. (2008) · Pharmacology Biochemistry and Behavior

Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior

Cited by 97

PRECLINICAL STUDY: Corticotropin‐releasing factor‐1 receptor antagonists decrease heroin self‐administration in long‐ but not short‐access rats

Greenwell, T. N., Funk, C. K., Cottone, P., Richardson, H. N., Chen, S. A., Rice, K. C., Zorrilla, E. P., & Koob, G. F. (2009) · Addiction Biology

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 87

Refractory dependence on opioid analgesics

Ballantyne, J. C., Sullivan, M. D., & Koob, G. F. (2019) · Pain

Pain Management and Opioid UseOpioid Use Disorder Treatment

Cited by 81

Neurobiology of Addiction

Koob, G. F. (2011) · Focus

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 79

Hypocretin receptor 2 antagonism dose-dependently reduces escalated heroin self-administration in rats

Schmeichel, B. E., Barbier, E., Misra, K. K., Contet, C., Schlosburg, J. E., Grigoriadis, D., Williams, J. P., Karlsson, C., Pitcairn, C., Heilig, M., et al. (2015) · Neuropsychopharmacology

Neurotransmitter Receptor Influence on BehaviorSleep and Wakefulness Research

Cited by 79

Control of craving by the prefrontal cortex

George, O., & Koob, G. F. (2013) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 75

κ opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake

Whitfield, T. W., Schlosburg, J. E., Wee, S., Gould, A., George, O., Grant, Y., Zamora-Martinez, E. R., Edwards, S., Crawford, E., Vendruscolo, L. F., et al. (2015) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 75

Corticotropin-releasing factor induces a place aversion independent of its neuroendocrine role

Cador, M., Ahmed, S. H., Koob, G. F., Le Moal, M., & Stinus, L. (1992) · Brain Research

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 74

A critical evaluation of a nicotine vaccine within a self-administration behavioral model

Moreno, A. Y., Azar, M. R., Warren, N. A., Dickerson, T. J., Koob, G. F., & Janda, K. D. (2010) · Molecular Pharmaceutics

Smoking Behavior and CessationMonoclonal and Polyclonal Antibodies Research

Cited by 73

A Phase 2, Double-Blind, Placebo-Controlled Randomized Trial Assessing the Efficacy of ABT-436, a Novel V1b Receptor Antagonist, for Alcohol Dependence

for the National Institute on Alcohol Abuse and Alcoholism Clinical Investigations Group (NCIG) Study Group, Ryan, M. L., Falk, D. E., Fertig, J. B., Rendenbach-Mueller, B., Katz, D. A., Tracy, K. A., Strain, E. C., Dunn, K. E., Kampman, K., et al. (2017) · Neuropsychopharmacology

Substance Abuse Treatment and OutcomesAlcohol Consumption and Health Effects

Cited by 72

CRF and urocortin decreased brain stimulation reward in the rat: reversal by a CRF receptor antagonist

Macey, D. J., Koob, G. F., & Markou, A. (2000) · Brain Research

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 69

Chronic CRF1receptor blockade reduces heroin intake escalation and dependence‐induced hyperalgesia

Park, P. E., Schlosburg, J. E., Vendruscolo, L. F., Schulteis, G., Edwards, S., & Koob, G. F. (2015) · Addiction Biology

Neuropeptides and Animal PhysiologyOpioid Use Disorder Treatment

Cited by 69

A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans

Aoun, E. G., Jimenez, V. A., Vendruscolo, L. F., Walter, N. A. R., Barbier, E., Ferrulli, A., Haass-Koffler, C. L., Darakjian, P., Lee, M. R., Addolorato, G., et al. (2018) · Molecular Psychiatry

Alcohol Consumption and Health EffectsNeurotransmitter Receptor Influence on Behavior

Cited by 60

Dysregulation of brain stress systems mediates compulsive alcohol drinking

Tunstall, B. J., Carmack, S. A., Koob, G. F., & Vendruscolo, L. F. (2017) · Current Opinion in Behavioral Sciences

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 55

Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks

Repunte-Canonigo, V., Shin, W., Vendruscolo, L. F., Lefebvre, C., van der Stap, L., Kawamura, T., Schlosburg, J. E., Alvarez, M., Koob, G. F., Califano, A., et al. (2015) · Genome Biology

Neurotransmitter Receptor Influence on BehaviorGene Regulatory Network Analysis

Cited by 52

INTERFERON-α AND TRANSFORMING GROWTH FACTOR-β1 REGULATE CORTICOTROPIN-RELEASING FACTOR RELEASE FROM THE AMYGDALA: COMPARISON WITH THE HYPOTHALAMIC RESPONSE**This work was supported by the NIMH AIDS Center, Grant MH 47680, and the Schumacher-Kramer Foundation.

RABER, J., KOOB, G. F., & BLOOM, F. E. (1997) · Neurochemistry International

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 50

Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies

Farokhnia, M., Rentsch, C. T., Chuong, V., McGinn, M. A., Elvig, S. K., Douglass, E. A., Gonzalez, L. A., Sanfilippo, J. E., Marchette, R. C. N., Tunstall, B. J., et al. (2022) · Molecular Psychiatry

Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on Behavior

Cited by 41

Glucocorticoid receptor modulators decrease alcohol self-administration in male rats

McGinn, M. A., Tunstall, B. J., Schlosburg, J. E., Gregory-Flores, A., George, O., de Guglielmo, G., Mason, B. J., Hunt, H. J., Koob, G. F., & Vendruscolo, L. F. (2021) · Neuropharmacology

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 35

PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury

Wagner, J., Park, L. M., Mukhopadhyay, P., Matyas, C., Trojnar, E., Damadzic, R., Jung, J., Bell, A. S., Mavromatis, L. A., Hamandi, A. M., et al. (2024) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsAlcohol Consumption and Health Effects

Cited by 26

Alcoholism, corticotropin-releasing factor, and molecular genetic allostasis

Koob, G. F. (2008) · Biological Psychiatry

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 14

Dissecting compulsive eating behavior into three elements

Moore, C. F., Sabino, V., Koob, G. F., & Cottone, P. (2019) · Compulsive Eating Behavior and Food Addiction

Eating Disorders and BehaviorsRegulation of Appetite and Obesity

Cited by 4