Koob, George F.

Addiction and Stress: An Allostatic View

Koob, G. F., & Schulkin, J. (2019) · Neuroscience & Biobehavioral Reviews

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 315

Genetic Differences in Response to Novelty and Spatial Memory Using a Two-Trial Recognition Task in Mice

Dellu, F., Contarino, A., Simon, H., Koob, G. F., & Gold, L. H. (2000) · Neurobiology of Learning and Memory

Memory and Neural MechanismsMemory Processes and Influences

Cited by 303

Corticotropin-releasing factor potentiates acoustic startle in rats: Blockade by chlordiazepoxide

Swerdlow, N. R., Geyer, M. A., Vale, W. W., & Koob, G. F. (1986) · Psychopharmacology

Neuropeptides and Animal PhysiologyStress Responses and Cortisol

Cited by 299

Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat.

Caine, S. B., & Koob, G. F. (1994) · The Journal of Pharmacology and Experimental Therapeutics

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 298

Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state

Richardson, H. N., Lee, S. Y., O’Dell, L. E., Koob, G. F., & Rivier, C. L. (2008) · European Journal of Neuroscience

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 294

Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats

Funk, C. K., Zorrilla, E. P., Lee, M.-J., Rice, K. C., & Koob, G. F. (2007) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 276

Septal vasopressin modulates social memory in male rats

Dantzer, R., Koob, G. F., Bluthe´, R.-M., & Le Moal, M. (1988) · Brain Research

Neuroendocrine regulation and behaviorMemory and Neural Mechanisms

Cited by 262

The dark side of food addiction

Parylak, S. L., Koob, G. F., & Zorrilla, E. P. (2011) · Physiology & Behavior

Eating Disorders and BehaviorsNeurotransmitter Receptor Influence on Behavior

Cited by 257

Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function

Ahmed, S. H., & Koob, G. F. (2005) · Psychopharmacology

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 254

Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies

Blednov, Y. A., Ponomarev, I., Geil, C., Bergeson, S., Koob, G. F., & Harris, R. A. (2012) · Addiction Biology

Neurotransmitter Receptor Influence on BehaviorAlcohol Consumption and Health Effects

Cited by 251

CRF–CRF 1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats

George, O., Ghozland, S., Azar, M. R., Cottone, P., Zorrilla, E. P., Parsons, L. H., O'Dell, L. E., Richardson, H. N., & Koob, G. F. (2007) · Proceedings of the National Academy of Sciences

Smoking Behavior and CessationNeuropeptides and Animal Physiology

Cited by 245

Suppression of corticotropin-releasing factor in the amygdala attenuates aversive consequences of morphine withdrawal

Heinrichs, S. C., Menzaghi, F., Schulteis, G., Koob, G. F., & Stinus, L. (1995) · Behavioural Pharmacology

Neuropeptides and Animal PhysiologyNeurotransmitter Receptor Influence on Behavior

Cited by 226

The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat

Hubner, C. B., & Koob, G. F. (1990) · Brain Research

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 218

Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals

Vendruscolo, L. F., Estey, D., Goodell, V., Macshane, L. G., Logrip, M. L., Schlosburg, J. E., McGinn, M. A., Zamora-Martinez, E. R., Belanoff, J. K., Hunt, H. J., et al. (2015) · Journal of Clinical Investigation

Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on Behavior

Cited by 218

Opioids, pain, the brain, and hyperkatifeia: a framework for the rational use of opioids for pain

Shurman, J., Koob, G. F., & Gutstein, H. B. (2010) · Pain Medicine

Opioid Use Disorder TreatmentPain Management and Opioid Use

Cited by 215

The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission

Chuong, V., Farokhnia, M., Khom, S., Pince, C. L., Elvig, S. K., Vlkolinsky, R., Marchette, R. C. N., Koob, G. F., Roberto, M., Vendruscolo, L. F., et al. (2023) · JCI Insight

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 214

Neuroprotective and Abstinence-Promoting Effects of Acamprosate: Elucidating the Mechanism of Action

De Witte, P., Littleton, J., Parot, P., & Koob, G. (2005) · CNS Drugs

Neuroscience and Neuropharmacology ResearchSubstance Abuse Treatment and Outcomes

Cited by 201

Opponent Process Model and Psychostimulant Addiction

Koob, G. F., Caine, S. B., Parsons, L., Markou, A., & Weiss, F. (1997) · Pharmacology Biochemistry and Behavior

Neurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Cited by 196

CRF system recruitment mediates dark side of compulsive eating

Cottone, P., Sabino, V., Roberto, M., Bajo, M., Pockros, L., Frihauf, J. B., Fekete, E. M., Steardo, L., Rice, K. C., Grigoriadis, D. E., et al. (2009) · Proceedings of the National Academy of Sciences

Regulation of Appetite and ObesityEating Disorders and Behaviors

Cited by 192

Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving ΔFosB and Calcium/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell

Robison, A. J., Vialou, V., Mazei-Robison, M., Feng, J., Kourrich, S., Collins, M., Wee, S., Koob, G., Turecki, G., Neve, R., et al. (2013) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 190

High-priority communication I Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence

Valdez, G. R., Zorrilla, E. P., Roberts, A. J., & Koob, G. F. (2003) · Alcohol

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 186

Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems

George, O., Le Moal, M., & Koob, G. F. (2012) · Physiology & Behavior

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 184

Lack of Self-Administration of Cocaine in Dopamine D 1 Receptor Knock-Out Mice

Caine, S. B., Thomsen, M., Gabriel, K. I., Berkowitz, J. S., Gold, L. H., Koob, G. F., Tonegawa, S., Zhang, J., & Xu, M. (2007) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 183

Addiction as a coping response: hyperkatifeia, deaths of despair, and COVID-19

Koob, G. F., Powell, P., & White, A. (2020) · American Journal of Psychiatry

Substance Abuse Treatment and OutcomesNeurotransmitter Receptor Influence on Behavior

Cited by 166