Takahashi, Joseph S.

Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science

Circadian rhythm and melatoninRegulation of Appetite and Obesity

Cited by 2,485

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninNonlinear Dynamics and Pattern Formation

Cited by 2,329

Central and Peripheral Circadian Clocks in Mammals

Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 2,265

Circadian integration of metabolism and energetics

Bass, J., & Takahashi, J. S. (2010) · Science

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 1,910

Mutagenesis and Mapping of a Mouse Gene, Clock , Essential for Circadian Behavior

Vitaterna, M. H., King, D. P., Chang, A.-M., Kornhauser, J. M., Lowrey, P. L., McDonald, J. D., Dove, W. F., Pinto, L. H., Turek, F. W., & Takahashi, J. S. (1994) · Science

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 1,632

Mop3 is an essential component of the master circadian pacemaker in mammals.

Bunger, M. K., Wilsbacher, L. D., Moran, S. M., Clendenin, C., Radcliffe, L. A., Hogenesch, J. B., Simon, M. C., Takahashi, J. S., & Bradfield, C. A. (2000) · Cell

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 1,621

The genetics of mammalian circadian order and disorder: implications for physiology and disease

Takahashi, J. S., Hong, H.-K., Ko, C. H., & McDearmon, E. L. (2008) · Nature Reviews Genetics

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 1,611

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

Marcheva, B., Ramsey, K. M., Buhr, E. D., Kobayashi, Y., Su, H., Ko, C. H., Ivanova, G., Omura, C., Mo, S., Vitaterna, M. H., et al. (2010) · Nature

Pancreatic function and diabetesCircadian rhythm and melatonin

Cited by 1,525

Transcriptional architecture and chromatin landscape of the core circadian clock in mammals

Koike, N., Yoo, S.-H., Huang, H.-C., Kumar, V., Lee, C., Kim, T.-K., & Takahashi, J. S. (2012) · Science

Circadian rhythm and melatoninGenomics and Chromatin Dynamics

Cited by 1,464

Molecular architecture of the mammalian circadian clock

Partch, C. L., Green, C. B., & Takahashi, J. S. (2014) · Trends in Cell Biology

Circadian rhythm and melatoninPlant Molecular Biology Research

Cited by 1,449

Positional Cloning of the Mouse Circadian Gene

King, D. P., Zhao, Y., Sangoram, A. M., Wilsbacher, L. D., Tanaka, M., Antoch, M. P., Steeves, T. D. L., Vitaterna, M. H., Kornhauser, J. M., Lowrey, P. L., et al. (1997) · Cell

Circadian rhythm and melatoninPlant Molecular Biology Research

Cited by 1,382

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

Welsh, D. K., Takahashi, J. S., & Kay, S. A. (2010) · Annual Review of Physiology

Circadian rhythm and melatoninNonlinear Dynamics and Pattern Formation

Cited by 1,216

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD + Biosynthesis

Ramsey, K. M., Yoshino, J., Brace, C. S., Abrassart, D., Kobayashi, Y., Marcheva, B., Hong, H.-K., Chong, J. L., Buhr, E. D., Lee, C., et al. (2009) · Science

Circadian rhythm and melatoninSirtuins and Resveratrol in Medicine

Cited by 1,126

Mammalian circadian biology: elucidating genome-wide levels of temporal organization

Lowrey, P. L., & Takahashi, J. S. (2004) · Annual Review of Genomics and Human Genetics

Circadian rhythm and melatoninPlant Molecular Biology Research

Cited by 976

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

Buhr, E. D., Yoo, S.-H., & Takahashi, J. S. (2010) · Science

Circadian rhythm and melatoninNonlinear Dynamics and Pattern Formation

Cited by 917

The Meter of Metabolism

Green, C. B., Takahashi, J. S., & Bass, J. (2008) · Cell

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 902

Mania-like behavior induced by disruption of CLOCK

Roybal, K., Theobold, D., Graham, A., DiNieri, J. A., Russo, S. J., Krishnan, V., Chakravarty, S., Peevey, J., Oehrlein, N., Birnbaum, S., et al. (2007) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninBipolar Disorder and Treatment

Cited by 803

Molecular components of the mammalian circadian clock

Buhr, E. D., & Takahashi, J. S. (2013) · Handbook of experimental pharmacology

Circadian rhythm and melatoninLight effects on plants

Cited by 738

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

Welsh, D. K., Yoo, S.-H., Liu, A. C., Takahashi, J. S., & Kay, S. A. (2004) · Current Biology

Circadian rhythm and melatoninNonlinear Dynamics and Pattern Formation

Cited by 726

Differential regulation of mammalian Period genes and circadian rhythmicity by cryptochromes 1 and 2

Vitaterna, M. H., Selby, C. P., Todo, T., Niwa, H., Thompson, C., Fruechte, E. M., Hitomi, K., Thresher, R. J., Ishikawa, T., Miyazaki, J., et al. (1999) · Proceedings of the National Academy of Sciences

Circadian rhythm and melatoninLight effects on plants

Cited by 690

System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock

Kornmann, B., Schaad, O., Bujard, H., Takahashi, J. S., & Schibler, U. (2007) · PLoS Biology

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 658

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

Bookout, A. L., de Groot, M. H. M., Owen, B. M., Lee, S., Gautron, L., Lawrence, H. L., Ding, X., Elmquist, J. K., Takahashi, J. S., Mangelsdorf, D. J., et al. (2013) · Nature Medicine

Fibroblast Growth Factor ResearchCircadian rhythm and melatonin

Cited by 545

Regulation of dopaminergic transmission and cocaine reward by the Clock gene

McClung, C. A., Sidiropoulou, K., Vitaterna, M., Takahashi, J. S., White, F. J., Cooper, D. C., & Nestler, E. J. (2005) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorCircadian rhythm and melatonin

Cited by 493

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

Silva, A. J., Simpson, E. M., Takahashi, J. S., Lipp, H.-P., Nakanishi, S., Wehner, J. M., Giese, K. P., Tully, T., Abel, T., Chapman, P. F., et al. (1997) · Neuron

Animal Genetics and ReproductionMemory and Neural Mechanisms

Cited by 479