Molecular architecture of the mammalian circadian clock

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Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

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The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator

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Transplanted Suprachiasmatic Nucleus Determines Circadian Period

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Molecular components of the mammalian circadian clock

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Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

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Extensive and divergent circadian gene expression in liver and heart

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Transcriptional architecture and chromatin landscape of the core circadian clock in mammals

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An h <i>Per2</i> Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

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The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

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Circadian Control of the NAD ⁺ Salvage Pathway by CLOCK-SIRT1

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Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock

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Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD ⁺ Biosynthesis

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A Functional Genomics Strategy Reveals Rora as a Component of the Mammalian Circadian Clock

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Physiological significance of a peripheral tissue circadian clock

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Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

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Mammalian circadian biology: elucidating genome-wide levels of temporal organization

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Mammalian genes are transcribed with widely different bursting kinetics

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Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

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Differential Functions of mPer1, mPer2, and mPer3 in the SCN Circadian Clock

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Circadian Regulator CLOCK Is a Histone Acetyltransferase

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Functional consequences of a CKIδ mutation causing familial advanced sleep phase syndrome

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Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

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A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism

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Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network

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Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

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Harmonics of Circadian Gene Transcription in Mammals

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System-Driven and Oscillator-Dependent Circadian Transcription in Mice with a Conditionally Active Liver Clock

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Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

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Rhythms of Mammalian Body Temperature Can Sustain Peripheral Circadian Clocks

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Defining mechanisms that regulate RNA polymerase II transcription in vivo

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Circadian orchestration of the hepatic proteome

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Circadian Mutant Overtime Reveals F-box Protein FBXL3 Regulation of Cryptochrome and Period Gene Expression

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The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification

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SCF Fbxl3 Controls the Oscillation of the Circadian Clock by Directing the Degradation of Cryptochrome Proteins

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Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation

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CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock

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Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver

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The After-Hours Mutant Reveals a Role for Fbxl3 in Determining Mammalian Circadian Period

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Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information

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Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

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A Molecular Mechanism for Circadian Clock Negative Feedback

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The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors

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Mammalian Per-Arnt-Sim Proteins in Environmental Adaptation

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Crystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator Complex

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Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding

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Dissecting the Functions of the Mammalian Clock Protein BMAL1 by Tissue-Specific Rescue in Mice

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Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

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SCFβ-TRCP Controls Clock-dependent Transcription via Casein Kinase 1-dependent Degradation of the Mammalian Period-1 (Per1) Proteinm

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The histone methyltransferase MLL1 permits the oscillation of circadian gene expression

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PERIOD1-Associated Proteins Modulate the Negative Limb of the Mammalian Circadian Oscillator

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Properties, Entrainment, and Physiological Functions of Mammalian Peripheral Oscillators

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Delay in Feedback Repression by Cryptochrome 1 Is Required for Circadian Clock Function

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Cold-Inducible RNA-Binding Protein Modulates Circadian Gene Expression Posttranscriptionally

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Circadian Oscillations of Protein-Coding and Regulatory RNAs in a Highly Dynamic Mammalian Liver Epigenome

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Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

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High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase

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Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillatorsPreprint

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Cell autonomy and synchrony of suprachiasmatic nucleus circadian oscillators

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CKIε/δ-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

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Histone Lysine Demethylase JARID1a Activates CLOCK-BMAL1 and Influences the Circadian Clock

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SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket

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Rhythmic PER Abundance Defines a Critical Nodal Point for Negative Feedback within the Circadian Clock Mechanism

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Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity

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Circadian oscillation of nucleotide excision repair in mammalian brain

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Genome-Wide RNA Polymerase II Profiles and RNA Accumulation Reveal Kinetics of Transcription and Associated Epigenetic Changes During Diurnal Cycles

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Structures of Drosophila Cryptochrome and Mouse Cryptochrome1 Provide Insight into Circadian Function

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Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening

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(Re)inventing the Circadian Feedback Loop

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The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1

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β-TrCP1-Mediated Degradation of PERIOD2 Is Essential for Circadian Dynamics

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Nocturnin, a Deadenylase in Xenopus laevis Retina

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The Polycomb Group Protein EZH2 Is Required for Mammalian Circadian Clock Function

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Feedback Regulation of Transcriptional Termination by the Mammalian Circadian Clock PERIOD Complex

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Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expressionPreprint

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Jumonji domain protein JMJD5 functions in both the plant and human circadian systems

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Genome-Wide Profiling of the Core Clock Protein BMAL1 Targets Reveals a Strict Relationship with Metabolism

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Circadian gene expression is resilient to large fluctuations in overall transcription rates

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The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ

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Biochemical Analysis of the Canonical Model for the Mammalian Circadian Clock

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Brain-Specific Rescue of Clock Reveals System-Driven Transcriptional Rhythms in Peripheral Tissue

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Regulation of alternative splicing by the circadian clock and food related cues

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The BMAL1 C terminus regulates the circadian transcription feedback loop

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Nocturnin Regulates Circadian Trafficking of Dietary Lipid in Intestinal Enterocytes

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Nuclear Receptors, Metabolism, and the Circadian ClockPreprint

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CIPC is a mammalian circadian clock protein without invertebrate homologues

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Stoichiometric Relationship among Clock Proteins Determines Robustness of Circadian Rhythms

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Immediate early response of the circadian polyA ribonuclease nocturnin to two extracellular stimuli

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Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis

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Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function

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Identification of a Novel Cryptochrome Differentiating Domain Required for Feedback Repression in Circadian Clock Function

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Flexible phase adjustment of circadian albumin D site-binding protein (Dbp) gene expression by CRYPTOCHROME1Preprint

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The circadian clock transcriptional complex: metabolic feedback intersects with epigenetic control

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Distinct Roles of DBHS Family Members in the Circadian Transcriptional Feedback Loop

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The mortality of MOP3 deficient mice with a systemic functional failure

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Quantitative Analyses of Cryptochrome-mBMAL1 Interactions

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Origins and consequences of transcriptional discontinuity

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Identification of two Amino Acids in the C-terminal Domain of Mouse CRY2 Essential for PER2 Interaction

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Novel Insights from Genetic and Molecular Characterization of the Human ClockPreprint

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Generation of a Novel Allelic Series of Cryptochrome Mutants via Mutagenesis Reveals Residues Involved in Protein-Protein Interaction and CRY2-Specific Repression

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Structure Function Analysis of Mammalian CryptochromesPreprint

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The Three Rs of Transcription: Recruit, Retain, and Recycle

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Ubiquitin ligases: structure, function, and regulation

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Circadian rhythm disruption and mental health

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Brain disorders? Not really: Why network structures block reductionism in psychopathology research

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Timing of light exposure affects mood and brain circuits

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Core circadian clock genes regulate leukemia stem cells in AML

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The future of rodent models in depression research

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Circadian rhythms, metabolism, and chrononutrition in rodents and humans

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Lung adenocarcinoma distally rewires hepatic circadian homeostasis

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The chronotherapeutic treatment of bipolar disorders: A systematic review and practice recommendations from the ISBD task force on chronotherapy and chronobiology

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Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus

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Modelling changes in sleep timing and duration across the lifespan: changes in circadian rhythmicity or sleep homeostasis?

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Endocrine Effects of Circadian Disruption

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Circadian Clock, Cancer, and Chemotherapy

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Circadian rhythms – from genes to physiology and disease

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The effects of self-selected light-dark cycles and social constraints on human sleep and circadian timing: a modeling approach

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Interactions by disorder – A matter of context

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Disrupted Sleep: From Molecules to Cognition

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Specificity in circadian clock feedback from targeted reconstitution of the NuRD corepressor

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Estrogen Permits Vasopressin Signaling in Preoptic Kisspeptin Neurons in the Female Mouse

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Time-of-day dependent effects of contractile activity on the phase of the skeletal muscle clock

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Circadian Disruption in Psychiatric Disorders

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Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback

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Circadian transcription from beta cell function to diabetes pathophysiology

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GIRK Channels Mediate the Nonphotic Effects of Exogenous Melatonin

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The Molecular Clock and Neurodegenerative Disease: A Stressful Time

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Tissue Biology: In Search of a New Paradigm

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When should I eat: A circadian view on food intake and metabolic regulation

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Chronic Light Exposure in the Middle of the Night Disturbs the Circadian System and Emotional Regulation

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Kidney-specific KO of the circadian clock protein PER1 alters renal Na⁺ handling, aldosterone levels, and kidney/adrenal gene expression

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Vasopressin regulates daily rhythms and circadian clock circuits in a manner influenced by sex

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Parental Exposure to Dim Light at Night Prior to Mating Alters Offspring Adaptive Immunity

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The Liver in the Eyes of a Chronobiologist

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Warming Up Your Tick-Tock: Temperature-Dependent Regulation of Circadian Clocks

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Evolutionary conservations, changes of circadian rhythms and their effect on circadian disturbances and therapeutic approaches

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How have our clocks evolved? Adaptive and demographic history of the out-of-African dispersal told by polymorphic loci in circadian genes

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Plant Circadian Rhythms: An Overview

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Circadian rhythms and physical activity

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Keeping time in the dark: Potato diel and circadian rhythmic gene expression reveals tissue‐specific circadian clocks

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Pharmacological and Genetic Approaches for the Study of Circadian Rhythms in Mammals

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