Overholtzer, Michael

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Stockwell, B. R., Friedmann Angeli, J. P., Bayir, H., Bush, A. I., Conrad, M., Dixon, S. J., Fulda, S., Gascón, S., Hatzios, S. K., Kagan, V. E., et al. (2017) · Cell

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 7,695

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 6,680

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

A Nonapoptotic Cell Death Process, Entosis, that Occurs by Cell-in-Cell Invasion

Overholtzer, M., Mailleux, A. A., Mouneimne, G., Normand, G., Schnitt, S. J., King, R. W., Cibas, E. S., & Brugge, J. S. (2007) · Cell

Cell death mechanisms and regulationCellular Mechanics and Interactions

Cited by 748

Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

Kim, S. E., Zhang, L., Ma, K., Riegman, M., Chen, F., Ingold, I., Conrad, M., Turker, M. Z., Gao, M., Jiang, X., et al. (2016) · Nature Nanotechnology

Ferroptosis and cancer prognosisNanoplatforms for cancer theranostics

Cited by 622

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

Florey, O., Kim, S. E., Sandoval, C. P., Haynes, C. M., & Overholtzer, M. (2011) · Nature Cell Biology

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 459

BIM Regulates Apoptosis during Mammary Ductal Morphogenesis, and Its Absence Reveals Alternative Cell Death Mechanisms

Mailleux, A. A., Overholtzer, M., Schmelzle, T., Bouillet, P., Strasser, A., & Brugge, J. S. (2007) · Developmental Cell

Cell death mechanisms and regulationDevelopmental Biology and Gene Regulation

Cited by 255

Competition between human cells by entosis

Sun, Q., Luo, T., Ren, Y., Florey, O., Shirasawa, S., Sasazuki, T., Robinson, D. N., & Overholtzer, M. (2014) · Cell Research

Cellular Mechanics and InteractionsCell death mechanisms and regulation

Cited by 233

Entosis Is Induced by Glucose Starvation

Hamann, J. C., Surcel, A., Chen, R., Teragawa, C., Albeck, J. G., Robinson, D. N., & Overholtzer, M. (2017) · Cell Reports

Cell death mechanisms and regulationCellular Mechanics and Interactions

Cited by 203

The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability

Overholtzer, M., Rao, P. H., Favis, R., Lu, X.-Y., Elowitz, M. B., Barany, F., Ladanyi, M., Gorlick, R., & Levine, A. J. (2003) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysSarcoma Diagnosis and Treatment

Cited by 193

A non-genetic route to aneuploidy in human cancers

Krajcovic, M., Johnson, N. B., Sun, Q., Normand, G., Hoover, N., Yao, E., Richardson, A. L., King, R. W., Cibas, E. S., Schnitt, S. J., et al. (2011) · Nature Cell Biology

Microtubule and mitosis dynamicsCellular Mechanics and Interactions

Cited by 188

WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase

Su, F., Overholtzer, M., Besser, D., & Levine, A. J. (2002) · Genes & Development

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 153

mTOR regulates phagosome and entotic vacuole fission

Krajcovic, M., Krishna, S., Akkari, L., Joyce, J. A., & Overholtzer, M. (2013) · Molecular Biology of the Cell

Cellular transport and secretionAutophagy in Disease and Therapy

Cited by 149

Induction of entosis by epithelial cadherin expression

Sun, Q., Cibas, E. S., Huang, H., Hodgson, L., & Overholtzer, M. (2014) · Cell Research

Cell death mechanisms and regulationCellular Mechanics and Interactions

Cited by 148

PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment

Krishna, S., Palm, W., Lee, Y., Yang, W., Bandyopadhyay, U., Xu, H., Florey, O., Thompson, C. B., & Overholtzer, M. (2016) · Developmental Cell

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 140

Mechanisms and consequences of entosis

Krishna, S., & Overholtzer, M. (2016) · Cellular and Molecular Life Sciences

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 118

Mechanisms of Ploidy Increase in Human Cancers: A New Role for Cell Cannibalism

Krajcovic, M., & Overholtzer, M. (2012) · Cancer Research

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

Cited by 102

Entosis: Cell-in-Cell Formation that Kills Through Entotic Cell Death

Florey, O., Kim, S., & Overholtzer, M. (2015) · Current Molecular Medicine

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 45

Autophagy proteins regulate cell engulfment mechanisms that participate in cancer

Kim, S. E., & Overholtzer, M. (2013) · Seminars in Cancer Biology

Autophagy in Disease and TherapyPhagocytosis and Immune Regulation

Cited by 35