Olson, Eric N.

Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

Lin, J., Wu, H., Tarr, P. T., Zhang, C.-Y., Wu, Z., Boss, O., Michael, L. F., Puigserver, P., Isotani, E., Olson, E. N., et al. (2002) · Nature

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 2,546

Transient Regenerative Potential of the Neonatal Mouse Heart

Porrello, E. R., Mahmoud, A. I., Simpson, E., Hill, J. A., Richardson, J. A., Olson, E. N., & Sadek, H. A. (2011) · Science

Congenital heart defects researchTissue Engineering and Regenerative Medicine

Cited by 2,545

MicroRNAs in Stress Signaling and Human Disease

Mendell, J. T., & Olson, E. N. (2012) · Cell

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 1,673

NFAT Signaling

Crabtree, G. R., & Olson, E. N. (2002) · Cell

Signaling Pathways in DiseaseNuclear Receptors and Signaling

Cited by 1,323

A micropeptide encoded by a putative long noncoding RNA regulates muscle performance

Anderson, D. M., Anderson, K. M., Chang, C.-L., Makarewich, C. A., Nelson, B. R., McAnally, J. R., Kasaragod, P., Shelton, J. M., Liou, J., Bassel-Duby, R., et al. (2015) · Cell

Muscle Physiology and DisordersRNA Research and Splicing

Cited by 1,216

Pervasive roles of microRNAs in cardiovascular biology

Small, E. M., & Olson, E. N. (2011) · Nature

MicroRNA in disease regulationCongenital heart defects research

Cited by 1,180

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

Simsek, T., Kocabas, F., Zheng, J., DeBerardinis, R. J., Mahmoud, A. I., Olson, E. N., Schneider, J. W., Zhang, C. C., & Sadek, H. A. (2010) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationCancer, Hypoxia, and Metabolism

Cited by 1,101

A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance

van Rooij, E., Quiat, D., Johnson, B. A., Sutherland, L. B., Qi, X., Richardson, J. A., Kelm, R. J., & Olson, E. N. (2009) · Developmental Cell

Muscle Physiology and DisordersMicroRNA in disease regulation

Cited by 960

Linking actin dynamics and gene transcription to drive cellular motile functions

Olson, E. N., & Nordheim, A. (2010) · Nature Reviews Molecular Cell Biology

Cellular Mechanics and InteractionsProtein Kinase Regulation and GTPase Signaling

Cited by 958

Hippo pathway effector Yap promotes cardiac regeneration

Xin, M., Kim, Y., Sutherland, L. B., Murakami, M., Qi, X., McAnally, J., Porrello, E. R., Mahmoud, A. I., Tan, W., Shelton, J. M., et al. (2013) · Proceedings of the National Academy of Sciences

Congenital heart defects researchHippo pathway signaling and YAP/TAZ

Cited by 895

MEF2: a central regulator of diverse developmental programs

Potthoff, M. J., & Olson, E. N. (2007) · Development

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 834

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

Molkentin, J. D., Black, B. L., Martin, J. F., & Olson, E. N. (1995) · Cell

Muscle Physiology and DisordersGenomics and Chromatin Dynamics

Cited by 819

Prevention of muscular dystrophy in mice by CRISPR/Cas9–mediated editing of germline DNA

Long, C., McAnally, J. R., Shelton, J. M., Mireault, A. A., Bassel-Duby, R., & Olson, E. N. (2014) · Science

CRISPR and Genetic EngineeringMuscle Physiology and Disorders

Cited by 720

Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21

Hatley, M. E., Patrick, D. M., Garcia, M. R., Richardson, J. A., Bassel-Duby, R., van Rooij, E., & Olson, E. N. (2010) · Cancer Cell

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 626

Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli

Renthal, W., Maze, I., Krishnan, V., Covington, H. E., Xiao, G., Kumar, A., Russo, S. J., Graham, A., Tsankova, N., Kippin, T. E., et al. (2007) · Neuron

Histone Deacetylase Inhibitors ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 599

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

Ye, F., Chen, Y., Hoang, T., Montgomery, R. L., Zhao, X.-H., Bu, H., Hu, T., Taketo, M. M., van Es, J. H., Clevers, H., et al. (2009) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsWnt/β-catenin signaling in development and cancer

Cited by 559

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy

Amoasii, L., Hildyard, J. C. W., Li, H., Sanchez-Ortiz, E., Mireault, A., Caballero, D., Harron, R., Stathopoulou, T.-R., Massey, C., Shelton, J. M., et al. (2018) · Science

Muscle Physiology and DisordersCRISPR and Genetic Engineering

Cited by 546

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

Xin, M., Olson, E. N., & Bassel-Duby, R. (2013) · Nature Reviews Molecular Cell Biology

Congenital heart defects researchTissue Engineering and Regenerative Medicine

Cited by 514

The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors

Acharya, A., Baek, S. T., Huang, G., Eskiocak, B., Goetsch, S., Sung, C. Y., Banfi, S., Sauer, M. F., Olsen, G. S., Duffield, J. S., et al. (2012) · Development

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 498

Molecular Pathways Controlling Heart Development

Olson, E. N., & Srivastava, D. (1996) · Science

Congenital heart defects researchDevelopmental Biology and Gene Regulation

Cited by 478

Regulation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) and mitochondrial function by MEF2 and HDAC5

Czubryt, M. P., McAnally, J., Fishman, G. I., & Olson, E. N. (2003) · Proceedings of the National Academy of Sciences

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 418

Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23∼27∼24 clusters

Zhou, Q., Gallagher, R., Ufret-Vincenty, R., Li, X., Olson, E. N., & Wang, S. (2011) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationAngiogenesis and VEGF in Cancer

Cited by 341

Muscle as a “Mediator” of Systemic Metabolism

Baskin, K. K., Winders, B. R., & Olson, E. N. (2015) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 333

The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3

Kuang, Z., Wang, Y., Li, Y., Ye, C., Ruhn, K. A., Behrendt, C. L., Olson, E. N., & Hooper, L. V. (2019) · Science

Gut microbiota and healthCircadian rhythm and melatonin

Cited by 330