Zhang, Kang

Identifying Medical Diagnoses and Treatable Diseases by Image-Based Deep Learning

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Genome-wide methylation profiles reveal quantitative views of human aging rates

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The practical implementation of artificial intelligence technologies in medicine

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Artificial Intelligence in Healthcare and EducationElectronic Health Records Systems

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A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Fritsche, L. G., Igl, W., Bailey, J. N. C., Grassmann, F., Sengupta, S., Bragg-Gresham, J. L., Burdon, K. P., Hebbring, S. J., Wen, C., Gorski, M., et al. (2016) · Nature Genetics

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Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding

Xu, Y., Li, X., Zhu, B., Liang, H., Fang, C., Gong, Y., Guo, Q., Sun, X., Zhao, D., Shen, J., et al. (2020) · Nature Medicine

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

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In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

Suzuki, K., Tsunekawa, Y., Hernandez-Benitez, R., Wu, J., Zhu, J., Kim, E. J., Hatanaka, F., Yamamoto, M., Araoka, T., Li, Z., et al. (2016) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

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DNA methylation aging clocks: challenges and recommendations

Bell, C. G., Lowe, R., Adams, P. D., Baccarelli, A. A., Beck, S., Bell, J. T., Christensen, B. C., Gladyshev, V. N., Heijmans, B. T., Horvath, S., et al. (2019) · Genome Biology

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Seven-Year Outcomes in Ranibizumab-Treated Patients in ANCHOR, MARINA, and HORIZON

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Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

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Clinically Applicable AI System for Accurate Diagnosis, Quantitative Measurements, and Prognosis of COVID-19 Pneumonia Using Computed Tomography

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A Variant of the HTRA1 Gene Increases Susceptibility to Age-Related Macular Degeneration

Yang, Z., Camp, N. J., Sun, H., Tong, Z., Gibbs, D., Cameron, D. J., Chen, H., Zhao, Y., Pearson, E., Li, X., et al. (2006) · Science

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Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

Sun, F., Park, K. K., Belin, S., Wang, D., Lu, T., Chen, G., Zhang, K., Yeung, C., Feng, G., Yankner, B. A., et al. (2011) · Nature

Nerve injury and regenerationNeurogenesis and neuroplasticity mechanisms

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Drusen complement components C3a and C5a promote choroidal neovascularization

Nozaki, M., Raisler, B. J., Sakurai, E., Sarma, J. V., Barnum, S. R., Lambris, J. D., Chen, Y., Zhang, K., Ambati, B. K., Baffi, J. Z., et al. (2006) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsComplement system in diseases

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Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits

Xue, Y., Ouyang, K., Huang, J., Zhou, Y., Ouyang, H., Li, H., Wang, G., Wu, Q., Wei, C., Bi, Y., et al. (2013) · Cell

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Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene ( LIPC )

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Seroprevalence of immunoglobulin M and G antibodies against SARS-CoV-2 in China

Xu, X., Sun, J., Nie, S., Li, H., Kong, Y., Liang, M., Hou, J., Huang, X., Li, D., Ma, T., et al. (2020) · Nature Medicine

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Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

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A transformer-based representation-learning model with unified processing of multimodal input for clinical diagnostics

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Deep-learning models for the detection and incidence prediction of chronic kidney disease and type 2 diabetes from retinal fundus images

Zhang, K., Liu, X., Xu, J., Yuan, J., Cai, W., Chen, T., Wang, K., Gao, Y., Nie, S., Xu, X., et al. (2021) · Nature Biomedical Engineering

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Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector: results of a phase I trial

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CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD

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Toll-like Receptor 3 and Geographic Atrophy in Age-Related Macular Degeneration

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Clinically applicable AI system for accurate diagnosis, quantitative measurements, and prognosis of COVID-19 pneumonia using computed tomography

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Murine Ccl2/Cx3cr1 Deficiency Results in Retinal Lesions Mimicking Human Age-Related Macular Degeneration

Tuo, J., Bojanowski, C. M., Zhou, M., Shen, D., Ross, R. J., Rosenberg, K. I., Cameron, D. J., Yin, C., Kowalak, J. A., Zhuang, Z., et al. (2007) · Investigative Opthalmology & Visual Science

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In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation

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