Most cited biochemistry, genetics and molecular biology papers
- Verified
An Eulerian path approach to DNA fragment assembly
Pevzner, P. A., Tang, H., & Waterman, M. S. (2001) · Proceedings of the National Academy of Sciences
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 1,352
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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
Noda, A., Ning, Y., Venable, S. F., Pereira-Smith, O. M., & Smith, J. R. (1994) · Experimental Cell Research
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,351
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Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.
Tian, H., McKnight, S. L., & Russell, D. W. (1997) · Genes & Development
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 1,351
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A copy number variation morbidity map of developmental delay
Cooper, G. M., Coe, B. P., Girirajan, S., Rosenfeld, J. A., Vu, T. H., Baker, C., Williams, C., Stalker, H., Hamid, R., Hannig, V., et al. (2011) · Nature Genetics
Genomic variations and chromosomal abnormalitiesGenomics and Rare Diseases
Cited by 1,351
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Genome-wide analysis of mammalian promoter architecture and evolution
Carninci, P., Sandelin, A., Lenhard, B., Katayama, S., Shimokawa, K., Ponjavic, J., Semple, C. A. M., Taylor, M. S., Engström, P. G., Frith, M. C., et al. (2006) · Nature Genetics
Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies
Cited by 1,350
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Detecting gene–gene interactions that underlie human diseases
Cordell, H. J. (2009) · Nature Reviews Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,350
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Drug delivery systems for RNA therapeutics
Paunovska, K., Loughrey, D., & Dahlman, J. E. (2022) · Nature Reviews Genetics
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 1,349
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Regulation of TORC1 by Rag GTPases in nutrient response
Kim, E., Goraksha-Hicks, P., Li, L., Neufeld, T. P., & Guan, K.-L. (2008) · Nature Cell Biology
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 1,349
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The effect of developmental and environmental factors on secondary metabolites in medicinal plants
Li, Y., Kong, D., Fu, Y., Sussman, M. R., & Wu, H. (2020) · Plant Physiology and Biochemistry
Plant biochemistry and biosynthesisPlant tissue culture and regeneration
Cited by 1,349
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Altered synaptic plasticity in a mouse model of fragile X mental retardation
Huber, K. M., Gallagher, S. M., Warren, S. T., & Bear, M. F. (2002) · Proceedings of the National Academy of Sciences
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 1,349
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Strategies for MMP inhibition in cancer: innovations for the post-trial era
Overall, C. M., & López-Otín, C. (2002) · Nature Reviews Cancer
Protease and Inhibitor MechanismsTGF-β signaling in diseases
Cited by 1,349
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Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions
Hynes, R. O., & Naba, A. (2012) · Cold Spring Harbor Perspectives in Biology
Cellular Mechanics and InteractionsCell Adhesion Molecules Research
Cited by 1,349
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Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
Nishida, K., Arazoe, T., Yachie, N., Banno, S., Kakimoto, M., Tabata, M., Mochizuki, M., Miyabe, A., Araki, M., Hara, K. Y., et al. (2016) · Science
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,349
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Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix
Walensky, L. D., Kung, A. L., Escher, I., Malia, T. J., Barbuto, S., Wright, R. D., Wagner, G., Verdine, G. L., & Korsmeyer, S. J. (2004) · Science
Cell death mechanisms and regulationChemical Synthesis and Analysis
Cited by 1,349
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Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites
Sandberg, R., Neilson, J. R., Sarma, A., Sharp, P. A., & Burge, C. B. (2008) · Science
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 1,349
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Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
Rudolph, K. L., Chang, S., Lee, H.-W., Blasco, M., Gottlieb, G. J., Greider, C., & DePinho, R. A. (1999) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,349
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A proteomic atlas of senescence-associated secretomes for aging biomarker development
Basisty, N., Kale, A., Jeon, O. H., Kuehnemann, C., Payne, T., Rao, C., Holtz, A., Shah, S., Sharma, V., Ferrucci, L., et al. (2020) · PLOS Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,348
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Bayesian approach to single-cell differential expression analysis
Kharchenko, P. V., Silberstein, L., & Scadden, D. T. (2014) · Nature Methods
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 1,348
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HIF prolyl‐hydroxylase 2 is the key oxygen sensor setting low steady‐state levels of HIF‐1α in normoxia
Berra, E., Benizri, E., Ginouvès, A., Volmat, V., Roux, D., & Pouysségur, J. (2003) · The EMBO Journal
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 1,348
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Gut microbiota-derived metabolites as central regulators in metabolic disorders
Agus, A., Clément, K., & Sokol, H. (2021) · Gut
Gut microbiota and healthMetabolomics and Mass Spectrometry Studies
Cited by 1,347
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Cell-signalling dynamics in time and space
Kholodenko, B. N. (2006) · Nature Reviews Molecular Cell Biology
Gene Regulatory Network AnalysisProtein Kinase Regulation and GTPase Signaling
Cited by 1,347
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A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis
Chawla, A., Boisvert, W. A., Lee, C.-H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., et al. (2001) · Molecular Cell
Cholesterol and Lipid MetabolismPeroxisome Proliferator-Activated Receptors
Cited by 1,347
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Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
Sanjuan, M. A., Dillon, C. P., Tait, S. W. G., Moshiach, S., Dorsey, F., Connell, S., Komatsu, M., Tanaka, K., Cleveland, J. L., Withoff, S., et al. (2007) · Nature
Autophagy in Disease and TherapyImmune Response and Inflammation
Cited by 1,347
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Programmable materials and the nature of the DNA bond
Jones, M. R., Seeman, N. C., & Mirkin, C. A. (2015) · Science
Advanced biosensing and bioanalysis techniquesSupramolecular Self-Assembly in Materials
Cited by 1,347
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